frondosin-a and Neoplasms

frondosin-a has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for frondosin-a and Neoplasms

Article	Year
Reactivity of acyclic (pentadienyl)iron(1+) cations: synthetic studies directed toward the frondosins. Organic & biomolecular chemistry, 2011, Oct-26, Volume: 9, Issue:22 A short, 4-step route to the scaffold of frondosin A and B is reported. The [1-methoxycarbonyl-5-(2',5'-dimethoxyphenyl)pentadienyl]Fe(CO)(3)(+) cation was prepared in two steps from (methyl 6-oxo-2,4-hexadienoate)Fe(CO)(3). Reaction of this cation with isopropenyl Grignard or cyclohexenyllithium reagents affords (2-alkenyl-5-aryl-1-methoxycarbonyl-3-pentene-1,5-diyl)Fe(CO)(3) along with other addition products. Oxidative decomplexation of these (pentenediyl)iron complexes, utilizing CuCl(2), affords 6-aryl-3-methoxycarbonyl-1,4-cycloheptadienes via the presumed intermediacy of a cis-divinylcyclopropane. Topics: Alkadienes; Animals; Aquatic Organisms; Autoimmune Diseases; Bridged Bicyclo Compounds; Cations; Chemistry, Pharmaceutical; Ferric Compounds; Humans; Interleukin-8; Iron; Magnetic Resonance Spectroscopy; Models, Molecular; Neoplasms; Oxidation-Reduction; Porifera; Receptors, Interleukin-8	2011

Article

Year

Reactivity of acyclic (pentadienyl)iron(1+) cations: synthetic studies directed toward the frondosins.

Organic & biomolecular chemistry, 2011, Oct-26, Volume: 9, Issue:22

A short, 4-step route to the scaffold of frondosin A and B is reported. The [1-methoxycarbonyl-5-(2',5'-dimethoxyphenyl)pentadienyl]Fe(CO)(3)(+) cation was prepared in two steps from (methyl 6-oxo-2,4-hexadienoate)Fe(CO)(3). Reaction of this cation with isopropenyl Grignard or cyclohexenyllithium reagents affords (2-alkenyl-5-aryl-1-methoxycarbonyl-3-pentene-1,5-diyl)Fe(CO)(3) along with other addition products. Oxidative decomplexation of these (pentenediyl)iron complexes, utilizing CuCl(2), affords 6-aryl-3-methoxycarbonyl-1,4-cycloheptadienes via the presumed intermediacy of a cis-divinylcyclopropane.

Topics: Alkadienes; Animals; Aquatic Organisms; Autoimmune Diseases; Bridged Bicyclo Compounds; Cations; Chemistry, Pharmaceutical; Ferric Compounds; Humans; Interleukin-8; Iron; Magnetic Resonance Spectroscopy; Models, Molecular; Neoplasms; Oxidation-Reduction; Porifera; Receptors, Interleukin-8

2011