Page last updated: 2024-11-05

fr 74366 and Diabetic Neuropathies

fr 74366 has been researched along with Diabetic Neuropathies in 9 studies

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's6 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shimoshige, Y2
Minoura, K2
Matsuoka, N1
Takakura, S4
Mutoh, S2
Kamijo, M1
Oka, M1
Kato, N1
Bird, SJ1
Brown, MJ1
Spino, C1
Watling, S1
Foyt, HL1
Greene, DA2
Arezzo, JC1
Brown, MB1
Stevens, MJ1
Feldman, EL1
Ikuma, K1
Yamamoto, T2
Kawamura, I3
Seki, J2
Goto, T2
Kihara, M1
Mitsui, Y1
Shioyama, M1
Hasegawa, T1
Takahashi, M1
Ao, S1
Shingu, Y1
Kikuchi, C1
Takano, Y1
Nomura, K1
Fujiwara, T1
Ohkubo, Y1
Notsu, Y1
Yamaguchi, I1

Reviews

2 reviews available for fr 74366 and Diabetic Neuropathies

ArticleYear
Aldose reductase inhibitors.
    Journal of enzyme inhibition, 2001, Volume: 16, Issue:6

    Topics: Aldehyde Reductase; Binding Sites; Clinical Trials as Topic; Crystallography, X-Ray; Diabetic Neurop

2001
Diabetic neuropathy: scope of the syndrome.
    The American journal of medicine, 1999, Aug-30, Volume: 107, Issue:2B

    Topics: Aldehyde Reductase; Animals; Chronic Disease; Controlled Clinical Trials as Topic; Diabetic Foot; Di

1999

Trials

1 trial available for fr 74366 and Diabetic Neuropathies

ArticleYear
Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy. Zenarestat Study Group.
    Neurology, 1999, Aug-11, Volume: 53, Issue:3

    Topics: Action Potentials; Aldehyde Reductase; Biopsy; Diabetic Neuropathies; Double-Blind Method; Female; H

1999

Other Studies

6 other studies available for fr 74366 and Diabetic Neuropathies

ArticleYear
Thirteen-month inhibition of aldose reductase by zenarestat prevents morphological abnormalities in the dorsal root ganglia of streptozotocin-induced diabetic rats.
    Brain research, 2009, Jan-09, Volume: 1247

    Topics: Aldehyde Reductase; Animals; Axons; Cell Death; Diabetes Mellitus, Experimental; Diabetic Neuropathi

2009
Value of repeated measures of nerve conduction and quantitative sensory testing in a diabetic neuropathy trial.
    Muscle & nerve, 2006, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Aldehyde Reductase; Algorithms; Cold Temperature; Data Interpretation, Stat

2006
The effects of zenarestat, an aldose reductase inhibitor, on peripheral neuropathy in Zucker diabetic fatty rats.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:11

    Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Neuropa

2000
The effects of zenarestat, an aldose reductase inhibitor, on minimal F-wave latency and nerve blood flow in streptozotocin-induced diabetic rats.
    Life sciences, 2001, Feb-09, Volume: 68, Issue:12

    Topics: Aldehyde Reductase; Animals; Blood Flow Velocity; Diabetes Mellitus, Experimental; Diabetic Neuropat

2001
Effect of zenarestat, an aldose reductase inhibitor, on endoneurial blood flow in experimental diabetic neuropathy of rat.
    Neuroscience letters, 2001, Sep-14, Volume: 310, Issue:2-3

    Topics: Aldehyde Reductase; Animals; Diabetic Neuropathies; Enzyme Inhibitors; Hydrogen; Male; Microelectrod

2001
Characterization of a novel aldose reductase inhibitor, FR74366, and its effects on diabetic cataract and neuropathy in the rat.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:1

    Topics: Aldehyde Reductase; Animals; Cataract; Diabetic Neuropathies; Diabetic Retinopathy; Female; Kinetics

1991