Page last updated: 2024-09-02

fr 139317 and Disease Models, Animal

fr 139317 has been researched along with Disease Models, Animal in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (70.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Chen, HI; Hsieh, NK; Liu, DD; Yang, YL1
Bratz, IN; Damron, DS; Guarini, G; Haney, RM; Meszaros, JG; Ohanyan, VA; Raman, P; Talasila, PK; Thodeti, CK1
Ishiye, M; Kosuge, K; Nakashima, M; Umemura, K1
Hamada, K; Nirei, H; Notsu, Y; Ono, T; Shoubo, M; Sogabe, K1
Fujita, K; Matsumura, Y; Miyazaki, Y; Morimoto, S; Takaoka, M2
Aarhus, LL; Burnett, JC; Clavell, AL; Heublein, DM; Mattingly, MT; Nir, A; Stevens, TL; Wright, S1
Ando, T; Fujishima, M; Fukuda, K; Okuda, S; Tamaki, K; Yanagida, T1
Burke, SE; Nelson, RA1

Other Studies

10 other study(ies) available for fr 139317 and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Endothelin and gelatinases in renal changes following blockade of nitric oxide synthase in hypertensive rats.
    The Chinese journal of physiology, 2008, Jun-30, Volume: 51, Issue:3

    Topics: Animals; Azepines; Blood Urea Nitrogen; Collagen; Creatinine; Cyclic GMP; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gelatinases; Glomerular Filtration Rate; Hypertension; Indoles; Kidney; Matrix Metalloproteinases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Tissue Inhibitor of Metalloproteinase-2

2008
Endothelin-mediated in vivo pressor responses following TRPV1 activation.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Azepines; Biphenyl Compounds; Blood Pressure; Capsaicin; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Femoral Artery; Indoles; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Receptor, Endothelin A; Receptor, Endothelin B; TRPV Cation Channels; Vasoconstriction; Vasoconstrictor Agents

2011
Effect of combination of a tissue-type plasminogen activator and an endothelin receptor antagonist, FR139317, in the rat cerebral infarction model.
    European journal of pharmacology, 1995, Feb-24, Volume: 275, Issue:1

    Topics: Animals; Azepines; Blood Platelets; Brain; Cell Adhesion; Cerebral Arterial Diseases; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Indoles; Intracranial Embolism and Thrombosis; Male; Radioimmunoassay; Rats; Rats, Wistar; Tissue Plasminogen Activator

1995
An endothelin ETA receptor antagonist, FR139317, ameliorates cerebral vasospasm in dogs.
    Life sciences, 1993, Volume: 52, Issue:23

    Topics: Animals; Azepines; Basilar Artery; Blood Pressure; Disease Models, Animal; Dogs; Endothelin Receptor Antagonists; Heart Rate; Indoles; Ischemic Attack, Transient; Male; Radiography; Subarachnoid Hemorrhage

1993
Role of endothelin-1 in hypertension induced by long-term inhibition of nitric oxide synthase.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: Administration, Oral; Analysis of Variance; Animals; Arginine; Azepines; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Hypertension; Indoles; Injections, Intravenous; Kidney; Male; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A

1995
Angiotensin converting enzyme inhibition modulates endogenous endothelin in chronic canine thoracic inferior vena caval constriction.
    The Journal of clinical investigation, 1996, Mar-01, Volume: 97, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Azepines; Disease Models, Animal; Dogs; Endothelins; Heart Failure; Hemodynamics; Indoles; Male; Vena Cava, Inferior

1996
Role of endothelin as a mitogen in experimental glomerulonephritis in rats.
    Kidney international, 1996, Volume: 49, Issue:5

    Topics: Animals; Azepines; Base Sequence; Cell Division; Disease Models, Animal; DNA Primers; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; In Situ Hybridization; Indoles; Macrophages; Male; Mitogens; Molecular Sequence Data; Monocytes; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; RNA, Messenger

1996
Effects of the endothelin ETA-receptor antagonist FR139317 on development of hypertension and cardiovascular hypertrophy in deoxycorticosterone acetate-salt hypertensive rats.
    Japanese journal of pharmacology, 1996, Volume: 70, Issue:4

    Topics: Analysis of Variance; Animals; Aorta, Thoracic; Azepines; Blood Pressure; Cardiomegaly; Desoxycorticosterone; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Hypertension; Indoles; Male; Mesenteric Arteries; Rats; Rats, Sprague-Dawley

1996
Endothelin-receptor antagonist FR 139317 reduces infarct size in a rabbit model when given before, but not after, coronary artery occlusion.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:1

    Topics: Animals; Azepines; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Heart; Indoles; Male; Myocardial Infarction; Rabbits; Time Factors

1997