fr 110302 has been researched along with Bronchial Hyperreactivity in 3 studies
*Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asano, M; Hiroi, J; Imai, T; Inamura, N; Inoue, H; Masunaga, T; Nakahara, K; Notsu, Y; Takishima, T; Yatabe, T | 1 |
| Kawai, Y; Kayakiri, H; Oku, T; Tanaka, H; Yatabe, T | 1 |
| Asano, M; Hamada, K; Inamura, N; Isono, T; Kohsaka, M; Nagayoshi, A; Nakahara, K; Notsu, Y; Oku, T; Ono, T | 1 |
3 other study(ies) available for fr 110302 and Bronchial Hyperreactivity
| Article | Year |
|---|---|
A 5-lipoxygenase inhibitor, FR110302, inhibits ozone-induced airway hyperresponsiveness in guinea pigs and dogs.
Topics: Acetylcholine; Administration, Oral; Airway Resistance; Animals; Bronchial Hyperreactivity; Dogs; Guinea Pigs; Lipoxygenase Inhibitors; Naphthols; Ozone; Quinolines | 1993 |
Studies on 5-lipoxygenase inhibitors. II. Discovery, optical resolution and enantioselective synthesis of FR110302, a highly potent non-redox type 5-lipoxygenase inhibitor.
Topics: Anaphylaxis; Animals; Blood Platelets; Bronchial Hyperreactivity; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene C4; Lipoxygenase Inhibitors; Male; Naphthols; Neutrophils; Optical Rotation; Quinolines; Rats; Rats, Sprague-Dawley; SRS-A; Stereoisomerism | 1998 |
A 5-lipoxygenase inhibitor, FR110302, suppresses airway hyperresponsiveness and lung eosinophilia induced by Sephadex particles in rats.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chromones; Dextrans; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Microspheres; Naphthols; Platelet Activating Factor; Prednisolone; Pulmonary Eosinophilia; Pyridines; Quinolines; Rats; Rats, Inbred Strains; SRS-A; Thiazoles | 1992 |