fpl 64176 has been researched along with Muscle Contraction in 4 studies
FPL 64176: an activator of L-type calcium channels; structure given in first source
FPL 64176 : 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flunarizine was ineffective except against contractions to low concentrations of noradrenaline." | 1.36 | Comparative effects of T-type and L-type Ca(2+)-antagonists against noradrenaline-induced contractions of human vas deferens. ( Amobi, N; Guillebaud, J; Smith, CH, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amobi, N | 2 |
| Guillebaud, J | 3 |
| Smith, IC | 2 |
| Smith, CH | 1 |
| Amobi, NI | 1 |
| Usowicz, MM | 1 |
| Gigg, M | 1 |
| Jones, LM | 1 |
| Cheung, CW | 1 |
| Hartley, SA | 1 |
4 other studies available for fpl 64176 and Muscle Contraction
| Article | Year |
|---|---|
Contractile actions of L-type Ca2+ agonists in human vas deferens and effects of structurally different Ca2+ antagonists.
Topics: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Humans; In Vitro Techn | 2010 |
Comparative effects of T-type and L-type Ca(2+)-antagonists against noradrenaline-induced contractions of human vas deferens.
Topics: Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Ty | 2010 |
Perspective on the role of P2X-purinoceptor activation in human vas deferens contractility.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Amides; Apamin; Calcium Channel Agonists; Calcium Channels, | 2012 |
Allosteric interactions at L-type calcium channels between FPL 64176 and the enantiomers of the dihydropyridine Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |