fpl 64176 has been researched along with Dystonia in 1 studies
FPL 64176: an activator of L-type calcium channels; structure given in first source
FPL 64176 : 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Systemic administration of the L-type calcium channel agonists +/-Bay K 8644 or FPL 64176 causes a characteristic pattern of motor dysfunction in normal C57BL/6J mice that resembles generalized dystonia." | 3.70 | Calcium channel agonists and dystonia in the mouse. ( Drew, T; Hess, EJ; Ho, T; Jinnah, HA; Rothstein, JD; Sepkuty, JP; Yitta, S, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jinnah, HA | 1 |
| Sepkuty, JP | 1 |
| Ho, T | 1 |
| Yitta, S | 1 |
| Drew, T | 1 |
| Rothstein, JD | 1 |
| Hess, EJ | 1 |
1 other study available for fpl 64176 and Dystonia
| Article | Year |
|---|---|
Calcium channel agonists and dystonia in the mouse.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2000 |