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fpl 64176 and Dystonia

fpl 64176 has been researched along with Dystonia in 1 studies

FPL 64176: an activator of L-type calcium channels; structure given in first source
FPL 64176 : 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group.

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"Systemic administration of the L-type calcium channel agonists +/-Bay K 8644 or FPL 64176 causes a characteristic pattern of motor dysfunction in normal C57BL/6J mice that resembles generalized dystonia."3.70Calcium channel agonists and dystonia in the mouse. ( Drew, T; Hess, EJ; Ho, T; Jinnah, HA; Rothstein, JD; Sepkuty, JP; Yitta, S, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jinnah, HA1
Sepkuty, JP1
Ho, T1
Yitta, S1
Drew, T1
Rothstein, JD1
Hess, EJ1

Other Studies

1 other study available for fpl 64176 and Dystonia

ArticleYear
Calcium channel agonists and dystonia in the mouse.
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2000