Page last updated: 2024-08-26

fpl 55712 and Asthma

fpl 55712 has been researched along with Asthma in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199019 (65.52)18.7374
1990's9 (31.03)18.2507
2000's1 (3.45)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kreft, AF; Musser, JH1
Bryant, RW; Kaminski, JJ; Kreutner, W; Lee, JF; McPhail, AT; Sherlock, MH; Tom, WC; Wong, SC1
Kay, AB; Lee, TH; Turner-Warwick, M; Walport, MJ; Wilkinson, AH1
Cade, JF; Clancy, RL; Pain, MC; Walker, SE1
Iwamoto, T; Koda, A; Nagai, H; Nishiyori, T; Takizawa, T; Tsuchiya, H1
Butler, J; Downes, H; Hanifin, JM; Hirshman, CA; Peters, J1
Wang, SM; Wang, SR; Yang, CM1
Ahmed, T; Birch, S; Greenblatt, DW; Marchette, B; Wanner, A1
Wanner, A1
Nishino, K; Ohashi, M; Uno, T1
Aishita, H; Furuya, T; Kobayashi, T; Muryobayashi, K; Nakagawa, N; Nambu, F; Obata, T; Okada, Y; Sawada, M; Terawaki, T1
Holgate, S; Sampson, A1
Young, RN1
Giovanazzi, S; Mezzetti, M; Nicosia, S; Rovati, GE1
Aishita, H; Motoishi, M; Nakagawa, N; Obata, T; Okada, Y; Terawaki, T1
Hashimoto, M; Hayashi, S; Nomura, Y1
Napier, FE; Shearer, MA; Temple, DM1
Ishii, A; Miyamoto, T; Mizushima, Y; Motoishi, M; Nakagawa, T; Nambu, F; Shida, T; Yui, Y1
Hosokawa, T; Irinoda, K; Maruyama, Y; Misawa, M; Mizuno, H; Ohno, H; Sugimoto, K; Takahashi, Y; Yanaura, S; Yoshimura, K1
Kawamura, T; Misawa, M; Takenouchi, K1
Abraham, WM; Garrido, R; Stevenson, JS1
Kohno, S; Ohata, K1
Barnes, N; Costello, J; Evans, J; Piper, P; Zakrzewski, J1
Cloud, ML; Fleisch, JH; Marshall, WS1
Bianco, S; Pasargiklian, M1
Beck, A; Bray, MA; Märki, F; Sallmann, A; Wenk, P1
Bentwich, Z; Berkenstadt, H; Bibi, H; Eliraz, A; Fink, A; Levin, S; Shahin, R1
Barbieri, EJ1
Weiss, EB1

Reviews

4 review(s) available for fpl 55712 and Asthma

ArticleYear
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
    Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines

1992
Discovery of montelukast: a once-a-day oral antagonist of leukotriene D4 for the treatment of chronic asthma.
    Progress in medicinal chemistry, 2001, Volume: 38

    Topics: Acetates; Administration, Oral; Animals; Asthma; Chromones; Chronic Disease; Cyclopropanes; Humans; Leukotriene Antagonists; Leukotriene D4; Lung; Quinolines; Sulfides

2001
Studies of leukotriene antagonists and synthesis inhibitors in man.
    Progress in clinical and biological research, 1988, Volume: 263

    Topics: Acetophenones; Asthma; Chromones; Epoprostenol; Humans; Hydroxyquinolines; Keto Acids; Leukotriene B4; Phenylbutyrates; Quinolines; SRS-A; Sulfones; Tetrazoles

1988
A brief review of preclinical and clinical studies with LY171883 and some comments on newer cysteinyl leukotriene receptor antagonists.
    Annals of the New York Academy of Sciences, 1988, Volume: 524

    Topics: Acetophenones; Animals; Asthma; Azoles; Bronchi; Chromones; Dicarboxylic Acids; Drug Evaluation; Drug Evaluation, Preclinical; Guinea Pigs; Haplorhini; Humans; Indazoles; Leukotriene E4; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Structure-Activity Relationship; Tetrazoles

1988

Trials

2 trial(s) available for fpl 55712 and Asthma

ArticleYear
Abnormal mucociliary transport in allergic patients with antigen-induced bronchospasm: role of slow reacting substance of anaphylaxis.
    The American review of respiratory disease, 1981, Volume: 124, Issue:2

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chromones; Cilia; Ethers; Female; Functional Residual Capacity; Humans; Male; Middle Aged; Mucus; Respiratory Function Tests; SRS-A; Trachea

1981
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evaluation; Drug Evaluation, Preclinical; Dust; Guinea Pigs; Histamine; Humans; Immunization, Passive; Indomethacin; Male; Ovalbumin; Pyrilamine; SRS-A

1991

Other Studies

23 other study(ies) available for fpl 55712 and Asthma

ArticleYear
Antiallergy agents. 1. Substituted 1,8-naphthyridin-2(1H)-ones as inhibitors of SRS-A release.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:11

    Topics: Animals; Asthma; Guinea Pigs; Histamine H1 Antagonists; Lung; Naphthyridines; SRS-A; Structure-Activity Relationship

1988
Slow-reacting substance of anaphylaxis antagonist FPL 55712 in chronic asthma.
    Lancet (London, England), 1981, Aug-08, Volume: 2, Issue:8241

    Topics: Adult; Asthma; Chromones; Chronic Disease; Ethers; Female; Humans; Male; Middle Aged; Respiratory Therapy; SRS-A

1981
Slow-reacting substance from alveolar macrophages--a mechanism of asthma?
    The Australian journal of experimental biology and medical science, 1981, Volume: 59, Issue:4

    Topics: Animals; Asthma; Atropine; Autacoids; Chromones; Cimetidine; Ethers; Guinea Pigs; Indomethacin; Macrophages; Methysergide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Trachea

1981
Pharmacological studies on newly synthesized anti-allergic agents, 2-methyl-3-piperidino-beta-propionaphtone hydrochloride (KZ-111) and 3-isobutyryl-2-isopropylpyrazole-[1, 5-a] pyridine (KC-404).
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:6

    Topics: Animals; Asthma; Chromones; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Hypersensitivity; In Vitro Techniques; Male; Muscle Contraction; Passive Cutaneous Anaphylaxis; Piperidines; Pyridines; Rats; Rats, Inbred Strains; SRS-A

1983
Role of mediators in allergic and nonallergic asthma in dogs with hyperreactive airways.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 54, Issue:4

    Topics: Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Chromones; Citrates; Citric Acid; Dogs; Guinea Pigs; Histamine; Hypersensitivity; Lung Compliance; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Respiratory Tract Diseases; Tissue Extracts

1983
[Characterization of slow reacting substance of anaphylaxis in asthmatic sputum].
    Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology, 1984, Volume: 17, Issue:1

    Topics: Adult; Animals; Arylsulfatases; Asthma; Chromones; Diphenhydramine; Female; Guinea Pigs; Histamine; Hot Temperature; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Sputum; SRS-A

1984
Alteration of tracheal mucociliary transport in airway disease. Effect of pharmacologic agents.
    Chest, 1981, Volume: 80, Issue:6 Suppl

    Topics: Animals; Asthma; Bronchitis; Bronchodilator Agents; Chromones; Cilia; Cystic Fibrosis; Dogs; Humans; Mucus; Polytetrafluoroethylene; Sheep; Smoking

1981
Effect of ibudilast, a novel antiasthmatic agent, on anaphylactic bronchoconstriction: predominant involvement of endogenous slow reacting substance of anaphylaxis.
    International archives of allergy and immunology, 1993, Volume: 101, Issue:3

    Topics: Acetylcholine; Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Asthma; Bronchoconstriction; Bronchodilator Agents; Calcimycin; Chromones; Guinea Pigs; Male; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pyrazoles; Pyridines; SRS-A

1993
Effect of a peptide leukotriene receptor antagonist, ONO-1078, on guinea-pig models of asthma.
    European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3

    Topics: Acetylcholine; Acute-Phase Reaction; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Chromones; Disease Models, Animal; Guinea Pigs; Hypersensitivity; Immunization; Male; Ovalbumin; Phthalazines; Pulmonary Eosinophilia; Pyrilamine; SRS-A

1993
Leukotriene modifiers in the treatment of asthma. Look promising across the board of asthma severity.
    BMJ (Clinical research ed.), 1998, Apr-25, Volume: 316, Issue:7140

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chromones; Humans; Leukotriene Antagonists; Lipoxygenase Inhibitors; Quinolines

1998
Heterogeneity of binding sites for ICI 198,615 in human lung parenchyma.
    Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7

    Topics: Asthma; Binding Sites; Chromones; Dicarboxylic Acids; Humans; Indazoles; Kinetics; Lung; Receptors, Immunologic; Receptors, Leukotriene; Software; SRS-A; Thiazoles

1992
In vitro antagonism of ONO-1078, a newly developed anti-asthma agent, against peptide leukotrienes in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Binding, Competitive; Chromones; Guinea Pigs; In Vitro Techniques; Leukotriene Antagonists; Lung; Male; Membranes; Prostaglandin-Endoperoxide Synthases; Radioligand Assay; SRS-A; Thromboxane-A Synthase; Trachea

1992
Inhibitory effect of methylprednisolone suleptanate (U-67590A) on anaphylactic bronchoconstriction in guinea pigs.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:3

    Topics: Anaphylaxis; Animals; Antigens; Asthma; Bronchial Diseases; Chromones; Constriction, Pathologic; Dose-Response Relationship, Drug; Guinea Pigs; Male; Methylprednisolone; Ovalbumin; SRS-A; Time Factors

1992
Nedocromil sodium inhibits antigen-induced contraction of human lung parenchymal and bronchial strips, and the release of sulphidopeptide-leukotriene and histamine from human lung fragments.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Asthma; Bronchi; Chromones; Histamine Release; Humans; In Vitro Techniques; Leukotrienes; Lung; Mites; Muscle Contraction; Muscle, Smooth; Nedocromil; Quinolones; SRS-A

1990
[Effects of flutropium bromide, a new antiasthma drug, on mediator release from mast cells and actions of mediators].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 91, Issue:2

    Topics: Animals; Asthma; Atropine; Atropine Derivatives; Chromones; Dogs; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Male; Mast Cells; Rats; Rats, Inbred Strains; Serotonin Antagonists; SRS-A

1988
A new bronchial asthma model using calcium ionophore A23187 in guinea pigs.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:3

    Topics: Administration, Inhalation; Animals; Asthma; Calcimycin; Chlorpheniramine; Chromones; Disease Models, Animal; Guinea Pigs; Injections, Intravenous; Male; SRS-A

1989
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles

1989
[Progress of therapeutic agents for asthma--3) Trends in the development of leukotriene inhibitory agents].
    Nihon rinsho. Japanese journal of clinical medicine, 1987, Volume: 45, Issue:8

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Asthma; Chromones; Dogs; Fatty Acids, Unsaturated; Guinea Pigs; Rats; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A

1987
Perspectives in the treatment of reversible airway obstruction.
    Respiration; international review of thoracic diseases, 1986, Volume: 50 Suppl 2

    Topics: Adrenal Cortex Hormones; Adrenergic alpha-Agonists; Ascorbic Acid; Asthma; Bronchitis; Calcium Channel Blockers; Chromones; Cromolyn Sodium; Humans; Lung Diseases, Obstructive; Prostaglandins E

1986
CGP 35949, an LTD4 antagonist with phospholipase inhibitory activity: a new approach to the treatment of asthma.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B

    Topics: Asthma; Azoles; Chromones; Humans; In Vitro Techniques; Phospholipases A; SRS-A; Structure-Activity Relationship; Tetrazoles

1987
Interferon modulates the leukotriene C4-induced non-adherence properties of leukocytes: acquisition of an asthmatic phenotype.
    Immunology letters, 1985, Volume: 10, Issue:3-4

    Topics: Adult; Asthma; Cell Adhesion; Cells, Cultured; Chromones; Cycloheximide; Humans; Interferon Type I; Leukocytes; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A

1985
Leukotriene antagonists: new antiasthmatic drugs.
    American family physician, 1987, Volume: 36, Issue:1

    Topics: Asthma; Bronchodilator Agents; Chromones; Humans; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A

1987
Toxic oxygen products alter calcium homeostasis in an asthma model.
    The Journal of allergy and clinical immunology, 1985, Volume: 75, Issue:6

    Topics: Anaphylaxis; Animals; Asthma; Calcium; Catalase; Chromones; Disease Models, Animal; Free Radicals; Guinea Pigs; Homeostasis; Muscle Relaxation; Muscle, Smooth; Oxygen; SRS-A; Superoxide Dismutase

1985