fp 83 has been researched along with Allodynia in 2 studies
FP 83: structure given in first source
Excerpt | Relevance | Reference |
---|---|---|
"Postoperative pain was managed by sufentanil titration in the postanesthetic care unit, followed by sufentanil infusion via patient-controlled analgesia." | 2.84 | Preoperative But Not Postoperative Flurbiprofen Axetil Alleviates Remifentanil-induced Hyperalgesia After Laparoscopic Gynecological Surgery: A Prospective, Randomized, Double-blinded, Trial. ( Li, Y; Shu, R; Wang, C; Wang, G; Wang, H; Yu, Y; Zhang, L; Zhao, Q, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Zhang, L | 2 |
Shu, R | 2 |
Zhao, Q | 2 |
Li, Y | 2 |
Wang, C | 1 |
Wang, H | 1 |
Yu, Y | 2 |
Wang, G | 2 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Postoperative Hyperalgesia Induced by Remifentanil in Patients Undergoing Lower Abdomimal Surgery[NCT02043366] | 180 participants (Actual) | Interventional | 2014-02-28 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The mechanical hyperalgesia threshold was defined as the lowest force (g) necessary to bend a Von Frey filament, which was perceived to be painful by the patient and measured by Von Frey filament at 24 hours postoperatively (NCT02043366)
Timeframe: 24 hours after surgery
Intervention | g (Mean) |
---|---|
Normal Saline | 60.57 |
Flurbiprofen AxetilⅠ | 78.29 |
Flurbiprofen AxetilⅡ | 68.50 |
Butorphanol | 79.7 |
Butorphanol-Flurbiprofen Axetil | 81.64 |
Sufentanil | 89.5 |
The skin around the incision is stimulated in steps of 5 mm at intervals of 1 s starting outside of the hyperalgesic area in the direction of the incision. The distance from the incision to the first point where a 'painful', 'sore' or 'sharper' feeling occurred is measured and noted. This measurement is repeated at predefined radial lines around the incision. To eliminate the variable length of incision, this length is subtracted from the longer diameter leaving four radial distances from the end and from the middle of the incision. The normalized area of hyperalgesia is calculated by summing up the areas of the remaining four triangles measured by and Von Frey filament. (NCT02043366)
Timeframe: 24 hours after surgery
Intervention | cm^2 (Mean) |
---|---|
Normal Saline | 60.46 |
Flurbiprofen AxetilⅠ | 53.64 |
Flurbiprofen AxetilⅡ | 56.57 |
Butorphanol | 54.00 |
Butorphanol-Flurbiprofen Axetil | 52.5 |
Sufentanil | 49.89 |
2 trials available for fp 83 and Allodynia
Article | Year |
---|---|
Preoperative But Not Postoperative Flurbiprofen Axetil Alleviates Remifentanil-induced Hyperalgesia After Laparoscopic Gynecological Surgery: A Prospective, Randomized, Double-blinded, Trial.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Female | 2017 |
Preoperative butorphanol and flurbiprofen axetil therapy attenuates remifentanil-induced hyperalgesia after laparoscopic gynaecological surgery: a randomized double-blind controlled trial.
Topics: Adult; Butorphanol; Double-Blind Method; Drug Therapy, Combination; Female; Flurbiprofen; Gynecologi | 2016 |