fotemustine has been researched along with Malignant Melanoma in 141 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (1.42) | 18.7374 |
1990's | 65 (46.10) | 18.2507 |
2000's | 44 (31.21) | 29.6817 |
2010's | 27 (19.15) | 24.3611 |
2020's | 3 (2.13) | 2.80 |
Authors | Studies |
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Bonnet, PA; Bressolle, F; David, N; Deleuze-Masquefa, C; Gayraud-Paniagua, S; Khier, S; Moarbess, G; Pinguet, F | 1 |
Franken, MG; Gheorghe, M; Haanen, JBAG; Leeneman, B; Uyl-de Groot, CA; van Baal, PHM | 1 |
Alamodi, A; Gomez, CR; Grada, Z; Haikel, Y; Hassan, M; Hassan, SL; Hassan, SY; Jamal, SME; Megahed, M; Murad, F; Santourlidis, S; Shareef, MA; Wahl, RU | 1 |
Bauer, S; Haubold, J; Ludwig, JM; Richly, H; Schaarschmidt, BM; Siveke, JT; Theysohn, JM; Umutlu, L; Wimmer, J | 1 |
Amato, G; Calabrò, L; Camerini, R; Chiarion-Sileni, V; Covre, A; Cutaia, O; Del Vecchio, M; Di Giacomo, AM; Ferrucci, PF; Giannarelli, D; Guida, M; Guidoboni, M; Maio, M; Mandalà, M; Marchetti, P; Quaglino, P; Valente, M | 1 |
Aprea, P; Ascierto, PA; Botti, G; Caracò, C; Cavalcanti, E; Comella, G; Cossu, A; Daponte, A; Gallo, C; Grimaldi, AM; Lastoria, S; Maiorino, L; Massidda, B; Mozzillo, N; Palmieri, G; Petrillo, A; Signoriello, S; Simeone, E | 1 |
Addeo, R; Caraglia, M; Facchini, S; Luce, A; Zappavigna, S | 1 |
Grosso, M; Pesce, M; Picasso, V; Queirolo, P; Spagnolo, F; Tornari, E | 1 |
Berniard, A; Carita, G; de Montrion, C; de Plater, L; Decaudin, D; Depil, S; Desjardins, L; Geneste, O; Kraus-Berthier, L; Lang, G; Lockhart, B; Némati, F; Pierré, A; Piperno-Neumann, S; Sastre-Garau, X; Vallerand, D | 1 |
Bedane, C; Combemale, P; Cupissol, D; Derrey, S; Dygai-Cochet, I; Lamant, L; Leccia, MT; Lubrano, V; Mazeau-Woynar, V; Mirabel, X; Modiano, P; Mourrégot, A; Planchamp, F; Rougé Bugat, ME; Sassolas, B; Siegrist, S; Thariat, J; Tiffet, O; Truc, G; Verdoni, L | 1 |
Baurain, JF; Durando, X; Gurunath, RK; Jouary, T; Kaempgen, E; Keilholz, U; Leyvraz, S; Marshall, E; Negrier, S; Piperno-Neumann, S; Schadendorf, D; Scheulen, M; Suciu, S; Testori, A; Vermorken, JB; Zdzienicki, M | 1 |
Aigner, B; Artl, M; Niederkorn, A; Richtig, E; Schwantzer, G; Wackernagel, W | 1 |
Annesi, D; Ascierto, PA; Calabrò, L; Danielli, R; Del Vecchio, M; Di Giacomo, AM; Fonsatti, E; Giannarelli, D; Guidoboni, M; Maccalli, C; Maio, M; Maurichi, A; Orgiano, L; Parmiani, G; Pilla, L; Queirolo, P; Ridolfi, R; Santinami, M; Simeone, E; Spadola, G; Testori, A | 1 |
Christmann, M; Kaina, B; Krumm, A; Loquai, C; Merz, S; Quiros, S; Roos, WP; Switzeny, OJ | 1 |
Chi, ZH; Cui, CL; Guo, J; Lian, HY; Si, L; Yuan, XQ | 1 |
Jorda, E; Lopez, V; Marti, N; Monteagudo, C; Pinazo, I | 1 |
Aitini, E; Ballardini, M; Bichisao, E; Fiorentini, G; Freschi, A; Guida, M; Michiara, M; Ridolfi, L; Ridolfi, R | 1 |
Cuttone, G; Iannolo, G; Korićanac, LB; Petrović, IM; Privitera, G; Ristić-Fira, AM; Valastro, LM; Zakula, JJ | 1 |
Ferri-Níguez, B; González-Tortosa, J; Ros de San Pedro, J | 1 |
Bonnet, PA; Bressolle, FM; Cooper, JF; Deleuze-Masquéfa, C; Gattacceca, F; Khier, S; Margout, D; Moarbess, G; Pinguet, F; Solassol, I | 1 |
Bechrakis, N; Foerster, MH; Keilholz, U; Krössin, M; Lindner, M; Schmittel, A; Schuster, R; Thiel, E; Wacker, F | 1 |
Asselain, B; Barillot, E; Bessard, MA; Couturier, J; Dahmani, A; Decaudin, D; Desjardins, L; Donnadieu, MH; Gentien, D; Lantz, O; Laurent, C; Mariani, P; Némati, F; Péguillet, I; Piperno-Neumann, S; Plancher, C; Reyes, C; Robert, D; Roman-Roman, S; Sastre-Garau, X; Saule, S | 1 |
Anichini, A; Bajetta, E; Bedognetti, D; Canova, S; Del Vecchio, M; Di Guardo, L; Morosini, P; Mortarini, R; Perrone, T; Pimpinelli, N; Queirolo, P; Sertoli, MR | 1 |
Colucci, G; Cramarossa, A; Fistola, E; Giudice, G; Guida, M; Lubello, K; Porcelli, M | 1 |
Di Giacomo, AM; Maio, M; Margolin, KA | 1 |
Anastassiou, G; Bornfeld, N; Freistuehler, M; Hilger, RA; Nareyeck, G; Scheulen, ME; Steuhl, KP; Westekemper, H; Zeschnigk, M | 1 |
Cuttone, G; Iannolo, G; Keta, O; Korićanac, L; Petrović, I; Ristić-Fira, A; Žakula, J | 1 |
Amadori, D; Calzolari, F; Farolfi, A; Guidoboni, M; Milandri, C; Ridolfi, L; Ridolfi, R; Scarpi, E | 1 |
Dréno, B; Quéreux, G | 1 |
Allegra, M; Bahadoran, P; Ballotti, R; Bertolotto, C; Deville, A; Giacchero, D; Lacour, JP; Ortonne, JP; Passeron, T; Ségalen, C; Thyss, A | 1 |
Auffret, M; Bertrand, M; Gauthier, S; Mortier, L; Wémeau-Stervinou, L | 1 |
Brocard, L; Daste, A; Durando, X; Gimbergues, P; Magné, N; Mansard, S; Thivat, E | 1 |
Annesi, D; Ascierto, PA; Di Giacomo, AM; Ferrucci, PF; Fonsatti, E; Giannarelli, D; Maio, M; Marasco, A; Nicoletti, SV; Parmiani, G; Pilla, L; Queirolo, P; Ridolfi, R; Rivoltini, L; Santinami, M; Simeone, E; Testori, A | 1 |
Garbe, C | 1 |
Beitzke, D; Berzaczy, D; Edelhauser, G; Funovics, M; Höeller, C; Lammer, J; Schicher, N | 1 |
Campello, C; Meunier, L; Renard, D; Stoebner, P | 1 |
Geissler, A; Gruss, C; Landthaler, M; Schalke, B; Stolz, W | 1 |
Foletto, M; Lise, M; Mocellin, S; Pilati, P; Rossi, CR | 1 |
Becker, JC; Bröcker, EB; Kämpgen, E; Lieb, W; Neumann, C; Schadendorf, D; Steinmann, A; Terheyden, P; Wagner, S; Wittenberg, G | 1 |
Aglione, S; Bajetta, E; Bernard-Marty, C; Buzzoni, R; Del Vecchio, M; Khayat, D; Nova, P; Rixe, O; Taillibert, S; Vitali, M | 1 |
Gschwendt, B; Helmbach, H; Kioschis, P; Korn, B; Lichter, P; Mollenhauer, J; Münstermann, E; Nessling, M; Poustka, A; Salowsky, R; Schadendorf, D; Schick, M; Will, RD; Wittig, R | 1 |
Bensadoun, RJ; Bonneterre, ME; Bourdin, S; Bui, BN; Clavel, M; Cupissol, D; De Gislain, C; Delaunay, MM; Guillot, B; Hauschild, A; Lesimple, T; Mohr, P; Mornex, F; Mousseau, M; Thomas, L; Tilgen, W; Ulrich, J | 1 |
Dréno, B; Wallon-Dumont, G | 1 |
Binder, B; Cerroni, L; Kerl, H; Richtig, E; Smolle, J; Wolf, IH | 1 |
Bensadoun, JR; Bonneterre, J; Bourdin, S; Clavel, M; Cupissol, D; de Gislain, C; Delaunay, MM; Guillot, B; Hauschild, A; Lesimple, T; Mohr, P; Mornex, F; Mousseau, M; Nguyen, BB; Thomas, L; Tilgen, W; Ulrich, J | 1 |
Bouissière, JL; Cuq, P; Evrard, A; Montero, JL; Montero, V; Passagne, I; Winum, JY | 1 |
De Salvo, GL; Foletto, M; Lejeune, FJ; Lise, M; Lopes, M; Mocellin, S; Pilati, PL; Pontes, L; Ribeiro, M; Rossi, CR | 1 |
Cupissol, D; Cuq, P; Depeille, P; Evrard, A; Montero, JL; Passagne, I; Vian, L; Winum, JY | 1 |
Aamdal, S; Avril, MF; Bieber, T; Bonerandi, JJ; Bonneterre, J; Fra, J; Gilde, K; Gonzalez Larriba, JL; Grob, JJ; Guillem Porta, V; Hauschild, A; Kamanabrou, D; Menu, Y; Mohr, P; Neuber, K; Pehamberger, H; Saïag, P; Scherrer, A; Sufliarsky, J; Weichenthal, M | 1 |
Eigentler, TK; Garbe, C | 1 |
Friedlander, M; Kurtovic, J; Riordan, SM; Singh-Grewal, I; Webster, GJ | 1 |
Bonenkamp, JJ; de Faria Lima, R; de Wilt, JH; Doubrovsky, A; Kam, PC; Thompson, JF | 1 |
Grange, JD; Kodjikian, L; Rivoire, M | 1 |
Acquati, M; Eggermont, AM; Kirkwood, JM; Queirolo, P; Rocca, A; Testori, A | 1 |
Karpenko, LG | 1 |
Carlander, B; Guillot, B; Khalil, Z; Pageot, N | 1 |
Bosshard, W; Fiorentini, G; Gillet, M; Humblet, Y; Keilholz, U; Leyvraz, S; Lotem, M; Pampallona, S; Peters, S; Piperno-Neumann, S; Popescu, R; Stupp, R; Voelter, V; Weitzen, R; Zografos, L | 1 |
Akimov, MA; Bogdanova, NV; Gershanovich, ML; Konstantinova, MM; Nosov, DA | 1 |
Clerico, MA; Marinozzi, C; Sozzi, P; Turrisi, G | 1 |
Bembenek, A; Hauschild, A; Kähler, KC; Kettelhack, C; Schlag, PM; Siegel, R | 1 |
Cuttone, G; Korićanac, LB; Petrović, IM; Privitera, G; Ristić-Fira, AM; Todorović, DV; Valastro, LM | 1 |
Amadori, D; Bonafe, M; Brigliadori, G; Fabbri, F; Rosetti, M; Storci, G; Tesei, A; Ulivi, P; Vannini, I; Zoli, W | 1 |
Bajetta, E; Canova, S; Del Vecchio, M; Messina, A | 1 |
Gill, S; Prince, HM; Shapiro, J; Westerman, D | 1 |
Camlica, H; Tas, F; Topuz, E | 1 |
Avril, MF | 1 |
Denys, A; Goitein, G; Halkic, N; Leyvraz, S; Pampallona, S; Peters, S; Schalenbourg, A; Voelter, V; Zografos, L | 1 |
Algermissen, B; Czarnetzki, BM; Kohlmus, CM; Schadendorf, D; Worm, M | 1 |
Bröcker, EB; Engel, E; Gérard, B; Glabbeke, MV; Israels, P; Kennes, C; Kleeberg, UR; Lejeune, F; Lentz, MA; Tilgen, W | 1 |
Barbé, V; Berlion, M; Berrile, J; Bizzari, JP; Fischel, JL; Formento, P; Milano, G | 2 |
Gerard, B; Punt, CJ; Tytgat, JH; van Liessum, PA | 1 |
A'Hern, R; Atkinson, H; Chang, J; Gore, ME; Lorentzos, A | 1 |
Falkson, CI; Falkson, G; Falkson, HC | 1 |
Berille, J; Bertrand, P; Bizzari, JP; Cour, V; Gerard, B; Giroux, B; Khayat, D; Sarkany, M | 1 |
Boaziz, C; Breau, JL; Israël, L; Mazeron, JJ; Morere, JF | 1 |
Bureau, B; Célérier, P; Dreno, B; Litoux, P | 1 |
Chaitchik, S; Merimsky, O | 1 |
Aliaga, A; Bizzari, JP; Cour, V; Lopez Lopez, JJ; Oliver, V; Perez, E; Ponchon, A | 1 |
Dougal, M; Lee, SM; Margison, GP; Thatcher, N | 1 |
Aamdal, S; Bizzari, JP; D'Incalci, M; Gerard, B; Lee, SM; Leyvraz, S; Lucas, C | 1 |
Lee, SM; Margison, GP; Thatcher, N; Woodcock, AA | 1 |
Antoine, E; Auclerc, G; Benhammouda, A; Bizzari, JP; Borel, C; Paraiso, D; Petit, T; Rixe, O; Soubrane, C; Weil, M | 1 |
Avril, MF; Borel, C; Giroux, B; Khayat, D; Monnier, A; Petit, T; Rixe, O; Weil, M | 1 |
Benoit, F; Bertheas, MF; Cambazard, F; Graille, MC; Guy, C; Lanthier, K; Perrot, JL | 1 |
Anderson, CM; Buzaid, AC; Legha, SS | 1 |
Bohndorf, W; Bröcker, EB; Engenhart, K; Flentje, M; Kämpgen, E; Messer, P; Tilgen, W; Trcka, J | 1 |
Bauer, J; Dorval, T; Gillet, M; Lejeune, F; Leyvraz, S; Meuli, R; Pampallona, S; Salmon, R; Spataro, V; Zografos, L | 1 |
Bartley, J; Eaglesham, GK; Hayes, MT; Parsons, PG; Prakash, AS | 1 |
Caponigro, F; Casaretti, R; Comella, G; Comella, P; Daponte, A; Fiore, F; Frasci, G; Gravina, A; Ionna, F; Mozzillo, N; Parziale, AP; Presutti, F | 1 |
Azevedo, MC; Lopes, M; Pontes, L; Ribeiro, M; Santos, JG | 1 |
Altenhoff, J; Breitbart, EW; Hossfeld, DK; Kowalzick, L; Marseille, A; Mohr, P; Sarkany, M; Stephan, U; Weichenthal, M | 1 |
Bartley, J; Hayes, MT; Parsons, PG | 1 |
Asselain, B; Desjardins, L; Dorval, T; Levy, C; Leyvraz, S; Plancher, C; Pouillart, P; Salmon, RJ; Schlienger, P; Servois, V | 1 |
Breitbart, E; Makki, A; Mohr, P; Schadendorf, D | 1 |
Bassères, N; Bizzari, JP; Bonerandi, JJ; Gérard, B; Grob, JJ; Richard, MA; Zarrour, H | 1 |
Casella, G; di Bonito, M; Fortuna, G; Iodice, F; Stellato, G; Tramontana, R; Tramontana, S | 1 |
Bröcker, EB; Göring, HD; Kämpgen, E; Kröning, Y; Trebing, D; Zierner, A | 1 |
Bauer, J; Biollaz, J; Buclin, T; Decosterd, LA; Gander, M; Lejeune, F; Leyvraz, S; Marzolini, C; Shen, F | 1 |
Bonerandi, JJ; Delaunay, M; Grob, JJ; Koeppel, MC; Laurans, R; Murraciole, X; Paul, K; Perragut, JC; Regis, J; Souteyrand, P; Wolkenstein, P | 1 |
Becker, JC; Bröcker, EB; Kämpgen, E; Rünger, TM; Terheyden, P | 1 |
Aamdal, S; Bohmann, T; Gerard, B; Lucas, C; Semb, KA | 1 |
Ablett, E; Dannoy, PA; Parsons, PG; Pedley, J; Sturm, RA | 1 |
Christmann, M; Dietel, M; Kaina, B; Kern, MA; Lage, H; Pick, M; Schadendorf, D | 1 |
Binder, M; Pehamberger, H; Seeber, A; Steiner, A; Wolff, K | 1 |
Belanich, M; Biollaz, J; Bonfanti, M; Colella, G; D'Incalci, M; Decosterd, L; Gander, M; Lejeune, F; Leyvraz, S; Liénard, D; Marzolini, C; Perey, L; Shen, F; Yarosh, D | 1 |
Comella, P; Daponte, A | 1 |
Gademann, G; Gollnick, H; Ulrich, J | 1 |
Diem, C; Emmert, S; Epe, B; Hellfritsch, D; Rünger, TM; Schadendorf, D | 1 |
Kern, MA; Lichter, P; Nessling, M; Schadendorf, D | 1 |
Becker, JC; Bröcker, EB; Kämpgen, E; Terheyden, P | 1 |
Ascierto, PA; Cellerino, R; Comella, G; Comella, P; Daponte, A; DeLena, M; Gravina, A; Marini, G; Melucci, MT; Palmieri, G | 1 |
Bock, M; Deichmann, M; Jäckel, A; Näher, H; Waldmann, V | 1 |
Christmann, M; Kaina, B; Lage, H; Pick, M; Schadendorf, D | 1 |
Egerer, G; Ho, AD; Keilholz, U; Lehnert, T; Max, R; Naeher, H | 1 |
Berlion, M; Marchal, S; Merlin, JL; Poullain, MG; Ramacci, C | 1 |
Chaitchik, S; Inbar, M; Kovner, F; Merimsky, O; Reider-Groswasser, I | 1 |
Chaitchik, S; Gerard, B; Inbar, M; Merimsky, O | 1 |
Elgren, TE; Hogenkamp, HP; MacFarlan, S; Nelson, LS; Schallreuter, KU; Yan-Sze, I | 1 |
Boaziz, C | 1 |
Avril, MF; Bonneterre, J; Cupissol, D; Fargeot, P; Fumoleau, P; Grob, JJ; Israel, L; Kalis, B; Kerbrat, P; Lambert, D | 1 |
Binder, M; Dorffner, R; Glebowski, E; Pehamberger, H; Winkler, A; Wolff, K | 1 |
Avril, MF; Bertrand, P; Bizzari, JP; Cour, V; Gerard, B; Khayat, D | 1 |
Chaitchik, S; Inbar, M; Merimsky, O | 1 |
Aamdal, S; Bohman, T; D'Incalci, M; Gerard, B | 1 |
Ring, J; Schallreuter, KU | 1 |
Berger, J; Brassow, FW; Breitbart, EW; Schallreuter, KU; Teichmann, W; Wenzel, E | 1 |
Breitbart, EW; Mensing, H; Schallreuter, KU; Wood, JM | 1 |
Lee, SM; Margison, GP; Thatcher, N | 1 |
Chaitchik, S; Inbar, M; Merimsky, O; Reider-Groswasser, I | 1 |
Boaziz, C; Breau, JL; Israël, L; Morere, JF | 1 |
Aigner, K; Auclerc, G; Bizzari, JP; Borel, C; Bousquet, JC; Buthiau, D; Cohen-Alloro, G; Cour, V; Khayat, D; Weil, M | 1 |
Aapro, M; Ardizzoni, A; Becquart, D; Calabresi, F; Dirix, L; Gerard, B; Wils, J | 1 |
Schallreuter, KU; Wood, JM | 1 |
Avril, MF; Banzet, P; Bonerandi, JJ; Bonneterre, J; Fumoleau, P; Jacquillat, C; Kerbrat, P; Khayat, D; Namer, M; Weil, M | 2 |
Avril, MF; Bonneterre, J; Bugat, R; Cupissol, D; Delaunay, M; Fumoleua, P; Grosshans, E; Israel, L; Kerbrat, P; Namer, M | 1 |
Bizzari, JP; Deloffre, P; Etienne, MC; Fischel, JL; Formento, P; Frenay, M; Gioanni, J; Milano, G | 1 |
Beerblock, K; Bizzari, JP; Deloffre, P; Lokiec, F; Lucas, C | 1 |
Banzet, P; Bizzari, JP; Frenay, M; Goupil, A; Jacquillat, C; Khayat, D; Naman, H; Namer, M; Rouesse, J; Weil, M | 1 |
20 review(s) available for fotemustine and Malignant Melanoma
Article | Year |
---|---|
A systematic literature review and network meta-analysis of effectiveness and safety outcomes in advanced melanoma.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azetidines; Benzimidazoles; Cancer Vaccines; Carboplatin; Dacarbazine; gp100 Melanoma Antigen; Humans; Hydrazines; Imidazoles; Interleukin-2; Ipilimumab; Lenalidomide; Melanoma; Network Meta-Analysis; Nitrosourea Compounds; Nivolumab; Organophosphorus Compounds; Oximes; Paclitaxel; Piperidines; Progression-Free Survival; Proportional Hazards Models; Pyridones; Pyrimidinones; Skin Neoplasms; Sorafenib; Survival Rate; Temozolomide; Treatment Outcome; Vemurafenib | 2019 |
Chemotherapy in the management of brain metastases: the emerging role of fotemustine for patients with melanoma and NSCLC.
Topics: Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds | 2013 |
[Cerebellopontine angle meningeal melanocytoma: a benign tumor?].
Topics: Antineoplastic Agents, Alkylating; Cerebellar Neoplasms; Cerebellopontine Angle; Diagnosis, Differential; Disease Progression; Fatal Outcome; Gait Disorders, Neurologic; Hearing Loss, Sensorineural; Humans; Magnetic Resonance Imaging; Male; Melanocytes; Melanoma; Meningeal Neoplasms; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neurilemmoma; Nevus; Nitrosourea Compounds; Organophosphorus Compounds | 2009 |
Brain metastasis in melanoma: clinical activity of CTLA-4 antibody therapy.
Topics: Antibodies, Monoclonal; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; CTLA-4 Antigen; Dacarbazine; Humans; Ipilimumab; Italy; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Survival Analysis; Temozolomide; United States | 2010 |
Fotemustine for the treatment of melanoma.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Humans; Melanoma; Molecular Structure; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Treatment Outcome | 2011 |
[Therapeutic strategies and systemic treatment of brain melanoma metastases].
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans; Immunotherapy; Indoles; Ipilimumab; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Palliative Care; Radiosurgery; Radiotherapy; Skin Neoplasms; Sulfonamides; Temozolomide; Vemurafenib | 2013 |
Isolated limb perfusion in locally advanced cutaneous melanoma.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Genetic Therapy; Humans; Melanoma; Melphalan; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Remission Induction; Reproducibility of Results; Skin Neoplasms; Tumor Necrosis Factor-alpha | 2002 |
Metastatic melanoma: chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Cisplatin; Clinical Trials as Topic; Cytokines; Dacarbazine; Genetic Therapy; Humans; Immunotherapy; Interferon-alpha; Interleukin-2; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Paclitaxel; Tamoxifen; Taxoids; Thalidomide | 2002 |
[Treatment of melanoma].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cell- and Tissue-Based Therapy; Cells, Cultured; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dacarbazine; Drug Therapy, Combination; Forecasting; Humans; Immunization, Passive; Immunotherapy; Immunotherapy, Active; Interferon-alpha; Interleukin-2; Lymph Node Excision; Lymphatic Metastasis; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; T-Lymphocytes, Cytotoxic; Temozolomide; Time Factors | 2003 |
[Therapy of malignant melanoma at the stage of distant metastasis].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dacarbazine; Disease Progression; Humans; Immunotherapy; Interferon-alpha; Interleukin-2; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Melanoma; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Palliative Care; Prognosis; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Skin Neoplasms; Temozolomide; Time Factors; Tomography, X-Ray Computed; Vindesine | 2004 |
Update: current management issues in malignant melanoma.
Topics: Chemotherapy, Adjuvant; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds | 2005 |
Fotemustine in the treatment of brain primary tumors and metastases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Glioma; Humans; Lung Neoplasms; Melanoma; Middle Aged; Multicenter Studies as Topic; Nitrosourea Compounds; Organophosphorus Compounds | 1994 |
[Malignant melanoma of the uvea].
Topics: Antineoplastic Agents; Brachytherapy; Combined Modality Therapy; Eye Enucleation; Female; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Uveal Neoplasms | 1993 |
Systemic treatments for advanced cutaneous melanoma.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine; Humans; Immunotherapy, Active; Interferon-alpha; Interleukin-2; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Remission Induction; Skin Neoplasms; Survival Rate; Temozolomide | 1995 |
[Immunochemotherapy of metastatic uveal melanoma with interferon alfa-2b, interleukin-2 and fotemustine. Case reports and review of the literature].
Topics: Antineoplastic Agents; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Interferon alpha-2; Interferon-alpha; Interleukin-2; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Treatment Outcome; Uveal Neoplasms | 1998 |
[Therapy of metastatic malignant uveal melanoma].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemoembolization, Therapeutic; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Male; Melanoma; Middle Aged; Multicenter Studies as Topic; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Prognosis; Skin Neoplasms; Time Factors; Uveal Neoplasms | 2001 |
[Contribution of a new nitrosourea compound: fotemustine].
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dacarbazine; Drug Therapy, Combination; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds | 1992 |
Fotemustine: an overview of its clinical activity in disseminated malignant melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Humans; Immunologic Factors; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Remission Induction; Vindesine | 1992 |
[Brain metastases of malignant melanomas].
Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Dacarbazine; Humans; Interleukin-2; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Semustine | 1991 |
Fotemustine (S 10036) in the intra-arterial treatment of liver metastasis from malignant melanoma. A phase II Study.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Evaluation; Female; Hematologic Diseases; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Remission Induction | 1991 |
45 trial(s) available for fotemustine and Malignant Melanoma
Article | Year |
---|---|
Primary Analysis and 4-Year Follow-Up of the Phase III NIBIT-M2 Trial in Melanoma Patients With Brain Metastases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Female; Follow-Up Studies; Humans; Ipilimumab; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Nivolumab; Organophosphorus Compounds; Skin Neoplasms; Survival Rate; Time Factors; Young Adult | 2021 |
Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Humans; Interferon alpha-2; Interferon-alpha; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Survival Analysis | 2013 |
Hepatic intra-arterial versus intravenous fotemustine in patients with liver metastases from uveal melanoma (EORTC 18021): a multicentric randomized trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Disease-Free Survival; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Prospective Studies; Survival Analysis; Uveal Neoplasms; Young Adult | 2014 |
Three-year follow-up of advanced melanoma patients who received ipilimumab plus fotemustine in the Italian Network for Tumor Biotherapy (NIBIT)-M1 phase II study.
Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Biological Therapy; Brain Neoplasms; Female; Follow-Up Studies; Humans; Ipilimumab; Male; Melanoma; Middle Aged; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Prognosis; Skin Neoplasms; Survival Rate | 2015 |
[Hepatic intra-arterial bio-chemotherapy for the treatment of melanoma patients with liver metastasis: a phase II clinical study].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytokine-Induced Killer Cells; Dacarbazine; Disease-Free Survival; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Hepatic Artery; Humans; Immunotherapy, Adoptive; Infusions, Intra-Arterial; Interleukin-2; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Remission Induction; Survival Rate; Thrombocytopenia; Young Adult | 2008 |
Multicentre, open, noncomparative Phase II trial to evaluate the efficacy and tolerability of fotemustine, cisplatin, alpha-interferon and interleukin-2 in advanced melanoma patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Disease Progression; Female; Humans; Immunologic Factors; Immunotherapy; Interferon-alpha; Interleukin-2; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Salvage Therapy; Skin Neoplasms; Survival Analysis | 2009 |
Bevacizumab plus fotemustine as first-line treatment in metastatic melanoma patients: clinical activity and modulation of angiogenesis and lymphangiogenesis factors.
Topics: Adult; Aged; Angiogenic Proteins; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Cells, Cultured; Female; Humans; Lymphangiogenesis; Male; Melanoma; Middle Aged; Neoadjuvant Therapy; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor C; Young Adult | 2010 |
Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial.
Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease-Free Survival; Female; Hematologic Diseases; Humans; Ipilimumab; Male; Melanoma; Middle Aged; Neoplasm Grading; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 2012 |
Treatment of disseminated ocular melanoma with sequential fotemustine, interferon alpha, and interleukin 2.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; Combined Modality Therapy; Female; Hepatic Artery; Humans; Immunotherapy; Infusions, Intra-Arterial; Interferon-alpha; Interleukin-2; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Prospective Studies; Survival Rate; Treatment Outcome; Uveal Neoplasms | 2002 |
A prospective randomized multicentre phase III trial of fotemustine plus whole brain irradiation versus fotemustine alone in cerebral metastases of malignant melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Disease Progression; Disease-Free Survival; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Prospective Studies; Skin Neoplasms; Survival Rate; Treatment Outcome | 2003 |
[Randomised phase III trial of fotemustine versus fotemustine plus whole brain irradiation in cerebral metastases of melanoma].
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow Diseases; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Disease Progression; Female; Humans; Life Tables; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Prospective Studies; Survival Analysis; Treatment Outcome | 2003 |
Phase I-II study on isolation antiblastic fotemustine perfusion after dacarbazine chemosensitization for advanced melanoma of the extremities.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Dacarbazine; Extremities; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Treatment Outcome | 2003 |
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Europe; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Quality of Life; Skin Neoplasms; Statistics, Nonparametric; Survival Analysis | 2004 |
[Effectiveness and safety of combined mustoforan, cisplatin and tamoxifen for disseminated cutaneous melanoma (results of the IC4-10036-46-RU trial)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Tamoxifen; Treatment Outcome | 2005 |
Hepatic arterial Fotemustine chemotherapy in patients with liver metastases from cutaneous melanoma is as effective as in ocular melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Eye Neoplasms; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Survival Analysis | 2007 |
Temozolomide in combination with fotemustine in patients with metastatic melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease-Free Survival; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Temozolomide | 2008 |
Adjuvant intra-arterial hepatic fotemustine for high-risk uveal melanoma patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Risk; Secondary Prevention; Survival Analysis; Uveal Neoplasms | 2008 |
Palliative therapy of melanoma patients with fotemustine. Inverse relationship between tumour load and treatment effectiveness. A multicentre phase II trial of the EORTC-Melanoma Cooperative Group (MCG).
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Palliative Care; Treatment Outcome | 1995 |
Fotemustine and tamoxifen combination therapy in metastatic malignant melanoma. A phase II study.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Tamoxifen | 1995 |
A phase II study of the sequential administration of dacarbazine and fotemustine in the treatment of cerebral metastases from malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Thrombocytopenia; Treatment Outcome | 1994 |
Phase II trial of fotemustine in patients with metastatic malignant melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Nausea; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Thrombocytopenia; Treatment Failure | 1994 |
Sequential administration of varying doses of dacarbazine and fotemustine in advanced malignant melanoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Melanoma; Middle Aged; Neutropenia; Nitrosourea Compounds; Organophosphorus Compounds; Respiratory Distress Syndrome; Thrombocytopenia | 1993 |
Fotemustine, dacarbazine, vindesine combination chemotherapy in advanced malignant melanoma: a phase II study of 43 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Remission Induction; Risk; Salvage Therapy; Survival Rate; Treatment Outcome; Vindesine | 1995 |
Complete remission seven years after treatment for metastatic malignant melanoma.
Topics: Antineoplastic Agents; Disease-Free Survival; Follow-Up Studies; Humans; Lymph Nodes; Lymphatic Metastasis; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Remission Induction; Splenic Neoplasms | 1996 |
Fotemustine given simultaneously with total brain irradiation in multiple brain metastases of malignant melanoma: report on a pilot study.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Radiotherapy Dosage; Treatment Outcome | 1996 |
Treatment of ocular melanoma metastatic to the liver by hepatic arterial chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Catheters, Indwelling; Eye Neoplasms; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Prospective Studies; Survival Analysis; Treatment Outcome | 1997 |
Fotemustine and dacarbazine plus recombinant interferon alpha 2a in thetreatment of advanced melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Survival Rate | 1997 |
Isolated limb perfusion with fotemustine after chemosensitization with dacarbazine in melanoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Arm; Chemotherapy, Cancer, Regional Perfusion; Dacarbazine; Female; Humans; Leg; Male; Melanoma; Middle Aged; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Skin Neoplasms | 1997 |
Fotemustine and interferon alpha2b in metastatic malignant melanoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Humans; Interferon-alpha; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Treatment Outcome | 1998 |
Combined treatment of stage IV melanoma patients with amifostine and fotemustine--a pilot study.
Topics: Amifostine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Drug Administration Schedule; Humans; Leukopenia; Melanoma; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Skin Neoplasms; Thrombocytopenia | 1998 |
Combined treatment with dacarbazine, cisplatin, fotemustine and tamoxifen in metastatic malignant melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine; Humans; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Survival Rate; Tamoxifen | 1998 |
Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Female; Glioma; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Temozolomide | 1998 |
Clinical experience of fotemustine, cisplatin and high dose tamoxifen in patients with metastatic malignant melanoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Tamoxifen; Time Factors | 1998 |
Sequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Glioma; Humans; Lymphocytes; Male; Melanoma; Middle Aged; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Temozolomide | 1999 |
Sequential interferon-alpha2b, interleukin-2 and fotemustine for patients with metastatic melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease-Free Survival; Female; Humans; Interferon alpha-2; Interferon-alpha; Interleukin-2; Lung Neoplasms; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Skin Neoplasms; Survival Rate | 2000 |
Cisplatin, dacarbazine, and fotemustine plus interferon alpha in patients with advanced malignant melanoma. A multicenter phase II study of the Italian Cooperative Oncology Group.
Topics: Adult; Aged; Anemia; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; CD146 Antigen; Cisplatin; Dacarbazine; Female; Fever; Follow-Up Studies; Humans; Interferon-alpha; Male; MART-1 Antigen; Melanoma; Melanoma-Specific Antigens; Membrane Glycoproteins; Middle Aged; Monophenol Monooxygenase; Nausea; Neoplasm Proteins; Neural Cell Adhesion Molecules; Neutropenia; Nitrosourea Compounds; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vomiting | 2000 |
Pilot study of hepatic intraarterial fotemustine chemotherapy for liver metastases from uveal melanoma: a single-center experience with seven patients.
Topics: Adult; Antineoplastic Agents; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Survival Analysis; Treatment Outcome; Uveal Neoplasms | 2001 |
Fotemustine--an advance in the treatment of metastatic malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 1992 |
Fotemustine: an overview of its clinical activity in disseminated malignant melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Humans; Immunologic Factors; Interferon alpha-2; Interferon-alpha; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Remission Induction; Vindesine | 1992 |
Fotemustine and DTIC combination in patients with disseminated malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Prospective Studies; Remission Induction | 1992 |
Fotemustine (S 10036) in the intra-arterial treatment of liver metastasis from malignant melanoma. A phase II Study.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Evaluation; Female; Hematologic Diseases; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Remission Induction | 1991 |
Multicenter phase II trial of the single agent fotemustine in patients with advanced malignant melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Evaluation; Europe; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 1991 |
Final report of the French multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Drug Evaluation; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds | 1990 |
Combination chemotherapy of dacarbazine and fotemustine in disseminated malignant melanoma. Experience of the French Study Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds | 1990 |
Chemotherapy by fotemustine in cerebral metastases of disseminated malignant melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Melanoma; Middle Aged; Multicenter Studies as Topic; Nitrosourea Compounds; Organophosphorus Compounds; Remission Induction; Tomography, X-Ray Computed | 1990 |
78 other study(ies) available for fotemustine and Malignant Melanoma
Article | Year |
---|---|
New imidazo[1,2-a]quinoxaline derivatives: synthesis and in vitro activity against human melanoma.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Imidazoles; Melanoma; Quinoxalines; Structure-Activity Relationship | 2009 |
Melanoma stem cell maintenance and chemo-resistance are mediated by CD133 signal to PI3K-dependent pathways.
Topics: AC133 Antigen; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Dual Specificity Phosphatase 1; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Stem Cells | 2020 |
Predictive impact of the inflammation-based indices in uveal melanoma liver metastases treated with transarterial hepatic chemoperfusion.
Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Biomarkers, Tumor; Blood Platelets; C-Reactive Protein; Chemotherapy, Cancer, Regional Perfusion; Female; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lymphocytes; Male; Melanoma; Melphalan; Middle Aged; Neutrophils; Nitrosourea Compounds; Organophosphorus Compounds; Prognosis; Proportional Hazards Models; Retrospective Studies; Tumor Burden; Uveal Neoplasms | 2021 |
Treatment of metastatic uveal melanoma with intravenous fotemustine.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Retrospective Studies; Survival Rate; Treatment Outcome; Uveal Neoplasms | 2013 |
Targeting Bcl-2/Bcl-XL induces antitumor activity in uveal melanoma patient-derived xenografts.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Cell Proliferation; Fluorescence Polarization; Heterocyclic Compounds, 3-Ring; Humans; Immunohistochemistry; Melanoma; Mice; Mice, SCID; Molecular Targeted Therapy; Myeloid Cell Leukemia Sequence 1 Protein; Nitrosourea Compounds; Organophosphorus Compounds; Peptides; Protein Binding; Sulfonamides; Survival Analysis; Uveal Neoplasms; Xenograft Model Antitumor Assays | 2014 |
[Management of patients with metastatic cutaneous melanoma: French national guidelines. French National Cancer Institute].
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Management; France; Humans; Indoles; Ipilimumab; Liver Neoplasms; Lung Neoplasms; Melanoma; Molecular Targeted Therapy; Neoplasm Staging; Nitrosourea Compounds; Oncogenes; Organophosphorus Compounds; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Sulfonamides; Temozolomide; Vemurafenib | 2014 |
Response of patients with metastatic uveal melanoma to combined treatment with fotemustine and sorafenib.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Liver Neoplasms; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Staging; Niacinamide; Nitrosourea Compounds; Organophosphorus Compounds; Phenylurea Compounds; Retrospective Studies; Sorafenib; Survival Rate; Uveal Neoplasms | 2014 |
B-Raf inhibitor vemurafenib in combination with temozolomide and fotemustine in the killing response of malignant melanoma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dacarbazine; Drug Synergism; Humans; Indoles; Melanoma; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Proto-Oncogene Proteins B-raf; Sulfonamides; Temozolomide; Vemurafenib | 2014 |
Follicular hyperplasia on the face subsequent to therapy with sorafenib. A new skin side effect.
Topics: Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Humans; Hyperplasia; Lung Neoplasms; Male; Melanoma; Niacinamide; Nitrosourea Compounds; Organophosphorus Compounds; Phenylurea Compounds; Pyridines; Skin; Skin Diseases; Skin Neoplasms; Sorafenib | 2009 |
Effects of fotemustine or dacarbasine on a melanoma cell line pretreated with therapeutic proton irradiation.
Topics: Cell Line, Tumor; Cell Survival; Dacarbazine; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Protons | 2009 |
Pharmacology of EAPB0203, a novel imidazo[1,2-a]quinoxaline derivative with anti-tumoral activity on melanoma.
Topics: Aminoquinolines; Animals; Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Imidazoles; Imiquimod; Injections, Intraperitoneal; Injections, Intravenous; Male; Melanoma; Mice; Mice, Nude; Nitrosourea Compounds; Organophosphorus Compounds; Quinoxalines; Rats; Skin Neoplasms; Xenograft Model Antitumor Assays | 2010 |
Transarterial chemoembolization of liver metastases from uveal melanoma after failure of systemic therapy: toxicity and outcome.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemoembolization, Therapeutic; Cisplatin; Disease-Free Survival; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Randomized Controlled Trials as Topic; Remission Induction; Treatment Outcome; Uveal Neoplasms | 2010 |
Establishment and characterization of a panel of human uveal melanoma xenografts derived from primary and/or metastatic tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Dacarbazine; Female; Gene Expression Profiling; Humans; In Situ Hybridization, Fluorescence; Male; Melanoma; Mice; Mice, SCID; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Oligonucleotide Array Sequence Analysis; Organophosphorus Compounds; Polymorphism, Single Nucleotide; Temozolomide; Tumor Cells, Cultured; Uveal Neoplasms; Xenograft Model Antitumor Assays | 2010 |
High activity of sequential low dose chemo-modulating Temozolomide in combination with Fotemustine in metastatic melanoma. A feasibility study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dose-Response Relationship, Drug; Feasibility Studies; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Temozolomide | 2010 |
Chemosensitivity of conjunctival melanoma cell lines to chemotherapeutic agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Conjunctival Neoplasms; Humans; Melanoma; Mitomycin; Nitrosourea Compounds; Organophosphorus Compounds; Tretinoin | 2011 |
Proton inactivation of melanoma cells enhanced by fotemustine.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Proton Therapy; Radiation Tolerance; Radiotherapy, Conformal | 2011 |
Liver metastases from melanoma: hepatic intra-arterial chemotherapy. A retrospective study.
Topics: Adult; Aged; Antineoplastic Agents; Carboplatin; Drug Delivery Systems; Drug Monitoring; Electronic Health Records; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Retrospective Studies; Survival Analysis; Uveal Neoplasms; Young Adult | 2011 |
Signalling and chemosensitivity assays in melanoma: is mutated status a prerequisite for targeted therapy?
Topics: Adolescent; Antineoplastic Agents; Benzenesulfonates; Butadienes; Cell Survival; Dacarbazine; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; Fatal Outcome; Female; Genes, ras; Humans; Melanoma; Molecular Targeted Therapy; Mutation; Niacinamide; Nitriles; Nitrosourea Compounds; Organophosphorus Compounds; Phenylurea Compounds; Phosphorylation; Precision Medicine; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-kit; Pyridines; Signal Transduction; Sorafenib; Treatment Outcome | 2011 |
[New toxicity of fotemustine: diffuse interstitial lung disease].
Topics: Aged, 80 and over; Antineoplastic Agents; Humans; Lung Diseases, Interstitial; Male; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 2012 |
Ipilimumab with fotemustine in metastatic melanoma.
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Female; Humans; Ipilimumab; Male; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 2012 |
Fotemustine chemoembolization of hepatic metastases from uveal melanoma: a retrospective single-center analysis.
Topics: Adult; Aged; Antineoplastic Agents; Chemoembolization, Therapeutic; Contrast Media; Ethiodized Oil; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Proportional Hazards Models; Retrospective Studies; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome; Uveal Neoplasms | 2012 |
Fotemustine-related leukoencephalopathy.
Topics: Aged; Antineoplastic Agents; Brain; Female; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Tomography Scanners, X-Ray Computed | 2013 |
Severe neurological disabilities after complete remission of advanced malignant melanoma following fotemustine therapy in combination with total brain irradiation.
Topics: Antineoplastic Agents, Alkylating; Atrophy; Brain; Brain Damage, Chronic; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dementia; Humans; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Palliative Care; Quality of Life; Radiotherapy, High-Energy; Remission Induction | 2002 |
Candidate genes for cross-resistance against DNA-damaging drugs.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Northern; Cisplatin; Cluster Analysis; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Nitrosourea Compounds; Nucleic Acid Hybridization; Organophosphorus Compounds; Tumor Cells, Cultured | 2002 |
Topical imiquimod in the treatment of metastatic melanoma to skin.
Topics: Adjuvants, Immunologic; Administration, Cutaneous; Aged; Aged, 80 and over; Aminoquinolines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Dacarbazine; Female; Humans; Imiquimod; Interferon alpha-2; Interferon-alpha; Knee; Leg; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Scalp; Skin Neoplasms; Treatment Outcome | 2003 |
Synthesis and biological evaluation of Fotemustine analogues on human melanoma cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatography, Thin Layer; Colony-Forming Units Assay; Coloring Agents; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Melanoma; Neutral Red; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds | 2003 |
Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression.
Topics: Antineoplastic Agents; Apoptosis; Carmustine; DNA Damage; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Guanine; Humans; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Tumor Cells, Cultured | 2003 |
Prevention of hepatotoxicity but loss of antimelanoma effect with combined fotemustine and anti-oxidant treatment.
Topics: Acetylcysteine; Adult; Antineoplastic Agents; Antioxidants; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Treatment Outcome | 2004 |
Isolated limb infusion with fotemustine after dacarbazine chemosensitisation for inoperable loco-regional melanoma recurrence.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Chemotherapy, Cancer, Regional Perfusion; Dacarbazine; Follow-Up Studies; Humans; Limb Salvage; Lower Extremity; Melanoma; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Remission Induction; Salvage Therapy; Skin Neoplasms; Treatment Outcome | 2004 |
Prolonged survival after resection of liver metastases from uveal melanoma and intra-arterial chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Dacarbazine; Fatal Outcome; Female; Follow-Up Studies; Hepatectomy; Humans; Injections, Intra-Arterial; Liver Neoplasms; Melanoma; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Survival Rate; Time Factors; Uveal Neoplasms | 2005 |
[Experience with use of mustoforan at the Clinical Oncological Dispensary of the Republic of Tatarstan].
Topics: Antineoplastic Agents; Cancer Care Facilities; Disease Progression; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Retrospective Studies; Russia; Skin Neoplasms; Treatment Outcome | 2005 |
Neurological toxicity during metastatic melanoma treatment with fotemustine.
Topics: Antineoplastic Agents; Brain Neoplasms; Female; Humans; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds | 2005 |
Intra-arterial hepatic fotemustine for the treatment of liver metastases from uveal melanoma: experience in 101 patients.
Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Injections, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Uveal Neoplasms | 2006 |
Persistent thrombocytopenia during melanoma treatment with fotemustine.
Topics: Aged; Antineoplastic Agents; Humans; Male; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Thrombocytopenia | 2006 |
Viability of a human melanoma cell after single and combined treatment with fotemustine, dacarbazine, and proton irradiation.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Dacarbazine; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Proton Therapy | 2007 |
Short interfering RNA directed against the SLUG gene increases cell death induction in human melanoma cell lines exposed to cisplatin and fotemustine.
Topics: Antineoplastic Agents; Cell Cycle; Cell Death; Cell Line, Tumor; Cisplatin; DNA Mutational Analysis; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; RNA, Small Interfering; Snail Family Transcription Factors; Transcription Factors; Tumor Suppressor Protein p53 | 2007 |
Impressive objective response in a patient with extensive metastatic melanoma including the brain.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Female; Humans; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Tomography, X-Ray Computed | 2007 |
Long-term survival and secondary acute leukemia after fotemustine therapy for metastatic melanoma.
Topics: Antineoplastic Agents; Humans; Leukemia, Myeloid; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Survival Analysis; Tomography, X-Ray Computed | 2007 |
[Fotemustine: muphoran].
Topics: Antineoplastic Agents; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 2007 |
Chemosensitivity testing of human malignant melanoma. A retrospective analysis of clinical response and in vitro drug sensitivity.
Topics: Antineoplastic Agents; Bleomycin; Carboplatin; Carmustine; Cisplatin; Dacarbazine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluorouracil; Forecasting; Humans; In Vitro Techniques; Lymphatic Metastasis; Melanoma; Methotrexate; Nitrosourea Compounds; Organophosphorus Compounds; Pilot Projects; Remission Induction; Retrospective Studies; Skin Neoplasms; Tumor Cells, Cultured; Vindesine | 1994 |
[Tamoxifen increases cytotoxic effects of fotemustine. Experimental results on cell lines of human melanoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; In Vitro Techniques; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1994 |
Tamoxifen enhances the cytotoxic effects of the nitrosourea fotemustine. Results on human melanoma cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1993 |
[Combination of fotemustine-dacarbazine and interferon alpha in the treatment of metastatic malignant melanoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Interferon-alpha; Karnofsky Performance Status; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Treatment Outcome | 1993 |
Fotemustine-dacarbazine combinations in the treatment of metastatic melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Humans; Liver Neoplasms; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds | 1993 |
Long-term complete remissions in patients with disseminated melanoma treated by fotemustine and dacarbazine.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Remission Induction | 1993 |
Dosage and cycle effects of dacarbazine (DTIC) and fotemustine on O6-alkylguanine-DNA alkyltransferase in human peripheral blood mononuclear cells.
Topics: Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Humans; Leukocytes, Mononuclear; Melanoma; Methyltransferases; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds | 1993 |
Activity and unexpected lung toxicity of the sequential administration of two alkylating agents--dacarbazine and fotemustine--in patients with melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Lung; Lung Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Respiratory Distress Syndrome | 1993 |
[Acquired myelodysplastic syndromes after treatment of melanoma with fotemustine and dacarbazine].
Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Fatal Outcome; Female; Humans; Melanoma; Middle Aged; Myelodysplastic Syndromes; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 1995 |
Mechanism of action of fotemustine, a new chloroethylnitrosourea anticancer agent: evidence for the formation of two DNA-reactive intermediates contributing to cytotoxicity.
Topics: Antineoplastic Agents; Cell Survival; DNA Adducts; DNA Methylation; DNA Repair; Dose-Response Relationship, Drug; Drug Stability; Guanine; HeLa Cells; Humans; Mass Spectrometry; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Tumor Cells, Cultured | 1997 |
In vitro evaluation of fotemustine as a potential agent for limb perfusion in melanoma.
Topics: Adenoviridae; Antineoplastic Agents; Carcinogens; Cell Cycle; Cell Survival; DNA, Neoplasm; Drug Evaluation; Humans; Hyperthermia, Induced; Melanoma; Methylnitronitrosoguanidine; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Perfusion; Skin Neoplasms; Tumor Cells, Cultured; Virus Replication | 1998 |
Treatment of liver metastases from uveal melanoma by combined surgery-chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Chemotherapy, Adjuvant; Cisplatin; Female; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Prospective Studies; Survival Analysis; Treatment Outcome; Uveal Neoplasms | 1998 |
Primary malignant melanoma of the vagina: case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Dacarbazine; Female; Follow-Up Studies; Humans; Interferon alpha-2; Interferon-alpha; Liver Neoplasms; Lymph Node Excision; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Recombinant Proteins; Vaginal Neoplasms | 1998 |
Effective combined immunochemotherapy with dinitrochlorobenzene and fotemustine in skin and brain metastases of melanoma.
Topics: Allergens; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Humans; Immunotherapy; Irritants; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Remission Induction; Salvage Therapy; Skin Neoplasms | 1998 |
Radiosurgery without whole brain radiotherapy in melanoma brain metastases. Club de Cancérologie Cutanée.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Humans; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Palliative Care; Radiosurgery; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome | 1998 |
UVB-specific regulation of gene expression in human melanocytic cells: cell cycle effects and implication in the generation of melanoma.
Topics: Antineoplastic Agents; beta-Galactosidase; Cell Cycle; Cisplatin; Demecolcine; Genes, fos; Genes, p53; HeLa Cells; HIV Long Terminal Repeat; Humans; Hydroxyurea; Inosine; Melanocytes; Melanoma; Methylnitronitrosoguanidine; Neoplasms, Radiation-Induced; Nitrosourea Compounds; Organophosphorus Compounds; Proto-Oncogene Proteins c-fos; Recombinant Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Ultraviolet Rays | 1998 |
Expression of DNA repair proteins hMSH2, hMSH6, hMLH1, O6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in melanoma cells with acquired drug resistance.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Carrier Proteins; Cisplatin; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Drug Resistance, Multiple; Etoposide; Humans; Melanoma; MutL Protein Homolog 1; MutS Homolog 2 Protein; N-Glycosyl Hydrolases; Neoplasm Proteins; Nitrosourea Compounds; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Promoter Regions, Genetic; Proto-Oncogene Proteins; RNA, Messenger; Transcription, Genetic; Vindesine | 1999 |
Treatment of metastatic malignant melanoma with dacarbazine plus fotemustine.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Treatment Outcome | 1998 |
Comments on: Treatment of metastatic malignant melanoma with dacarbazine plus fotemustine, Seeber, et al., Eur J Cancer 1998, 34, 2129-2131.
Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds | 1999 |
Management of cerebral metastases from malignant melanoma: results of a combined, simultaneous treatment with fotemustine and irradiation.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; Humans; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Retrospective Studies; Survival Analysis | 1999 |
Alterations of DNA repair in melanoma cell lines resistant to cisplatin, fotemustine, or etoposide.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cisplatin; DNA Repair; DNA, Neoplasm; Drug Resistance; Etoposide; Humans; Melanoma; Microsatellite Repeats; Nitrosourea Compounds; Organophosphorus Compounds; Oxygen; Tumor Cells, Cultured; Ultraviolet Rays | 2000 |
Association of genomic imbalances with resistance to therapeutic drugs in human melanoma cell lines.
Topics: Aneuploidy; Antineoplastic Agents; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 9; Cisplatin; DNA Mutational Analysis; DNA Probes; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Etoposide; Genome, Human; Humans; Melanoma; Nitrosourea Compounds; Nucleic Acid Hybridization; Organophosphorus Compounds; Selection, Genetic; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Vindesine | 1999 |
Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT.
Topics: Antineoplastic Agents; Azacitidine; Blotting, Southern; DNA Methylation; DNA Repair; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Enzyme Reactivators; Gene Amplification; Gene Expression; Guanine; Humans; Melanoma; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Promoter Regions, Genetic; Tumor Cells, Cultured | 2001 |
Enhancement of fotemustine (Muphoran) cytotoxicity by amifostine in malignant melanoma cell lines.
Topics: Amifostine; Antineoplastic Agents; Cell Survival; Drug Synergism; Humans; Inhibitory Concentration 50; Melanoma; Mercaptoethylamines; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Radiation-Protective Agents; Tumor Cells, Cultured | 2002 |
Cerebral metastatic melanoma: correlation between clinical and CT findings.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Tomography, X-Ray Computed | 1992 |
Ribonucleotide diphosphate reductase from human metastatic melanoma.
Topics: Antineoplastic Agents; Cell-Free System; Electron Spin Resonance Spectroscopy; Humans; Hydroxyurea; Kinetics; Macromolecular Substances; Melanoma; Models, Structural; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Ribonucleoside Diphosphate Reductase | 1992 |
Fotemustine plus dacarbazine for malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Evaluation; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Thrombocytopenia | 1992 |
Fotemustine plus dacarbazine in advanced stage III malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Leukopenia; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Thrombocytopenia | 1992 |
Sequential administration of dacarbazine and fotemustine in patients with disseminated malignant melanoma--an effective combination with unexpected toxicity.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Pneumonia | 1992 |
A probable mechanism for hyperpigmentation by fotemustine.
Topics: Antineoplastic Agents; Humans; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Pigmentation Disorders; Thioredoxin-Disulfide Reductase | 1992 |
Positive phase II study in the treatment of advanced malignant melanoma with fotemustine.
Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms; Time Factors | 1991 |
Local treatment of cutaneous and subcutaneous metastatic malignant melanoma with fotemustine.
Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Injections, Intralesional; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 1991 |
O6-alkylguanine-DNA alkyltransferase depletion and regeneration in human peripheral lymphocytes following dacarbazine and fotemustine.
Topics: Adenosine Triphosphatases; Adult; Aged; Antineoplastic Agents; Dacarbazine; Female; Humans; Kinetics; Lymphocytes; Male; Melanoma; Methyltransferases; Middle Aged; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds | 1991 |
Fotemustine with or without dacarbazine for brain metastases of malignant melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Evaluation; Humans; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds | 1991 |
Sensitivity and resistance in human metastatic melanoma to the new chloroethylnitrosourea anti-tumor drug Fotemustine.
Topics: Antineoplastic Agents; Cell Membrane; Chromatography, High Pressure Liquid; Drug Resistance; Glutathione Reductase; Humans; Kinetics; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Thioredoxin-Disulfide Reductase | 1991 |
[Fotemustine in the treatment of metastatic malignant melanoma. Overall analysis of results].
Topics: Antineoplastic Agents; Dacarbazine; Drug Synergism; Drug Therapy, Combination; Humans; Melanoma; Neoplasm Metastasis; Nitrosourea Compounds; Organophosphorus Compounds; Skin Neoplasms | 1990 |
In vitro chemosensitivity testing of Fotemustine (S 10036), a new antitumor nitrosourea.
Topics: Antineoplastic Agents; Carmustine; Cell Division; Cisplatin; Dacarbazine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Lomustine; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Thymidine; Tumor Cells, Cultured | 1990 |
[Study of the clinical pharmacokinetics of fotemustine in various tumor indications].
Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Male; Melanoma; Metabolic Clearance Rate; Middle Aged; Neoplasm Metastasis; Neoplasms; Nitrosourea Compounds; Organophosphorus Compounds | 1989 |
Interim report of phase II study of new nitrosourea S 10036 in disseminated malignant melanoma.
Topics: Antineoplastic Agents; Drug Evaluation; Female; Humans; Male; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds | 1988 |