Page last updated: 2024-08-26

fotemustine and Glioma

fotemustine has been researched along with Glioma in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (26.09)18.2507
2000's8 (34.78)29.6817
2010's9 (39.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gaviani, P; Lamperti, E; Salmaggi, A; Silvani, A; Simonetti, G1
Bellu, L; Cecchin, D; Della Puppa, A; Farina, P; Lombardi, G; Pambuku, A; Zagonel, V1
Carapella, CM; Carosi, MA; Cognetti, F; Fabi, A; Giannarelli, D; Marucci, L; Metro, G; Pace, A; Piludu, F; Pompili, A; Telera, S; Vaccaro, V; Vari, S; Vidiri, A; Villani, V1
Agolli, L; Caporello, P; Enrici, RM; Esposito, V; Falco, T; Lanzetta, G; Minniti, G; Osti, MF; Scaringi, C1
Benavides, M; Berros, JP; Cano, JM; Ceballos, I; Covela, M; Fernández, I; Fuster, J; García Bueno, JM; García, A; Manneh, R; Moreno, V; Pérez-Segura, P; Quintanar, T; Sepúlveda, J; Vaz, MA1
Bartolotti, M; Brandes, AA; Franceschi, E; Tosoni, A1
Carapella, CM; Carosi, M; Cognetti, F; Fabi, A; Jandolo, B; Maschio, M; Metro, G; Mirri, MA; Pace, A; Russillo, M; Sperduti, I; Telera, S; Vidiri, A1
Beauchesne, PD; Bernier, V; Carnin, C; Taillandier, L1
Carapella, CM; Carosi, M; Cognetti, F; Fabi, A; Lanzetta, G; Maschio, M; Metro, G; Pace, A; Russillo, M; Sperduti, I; Telera, S; Vidiri, A1
Bonizzoni, E; Detti, B; Fabrini, MG; Lolli, I; Paccapelo, A; Perrone, F; Perrone, T; Santoni, M; Savio, G; Scoccianti, S; Silvano, G1
Codacci-Pisanelli, G; Della Rocca, C; Frati, L; Gulino, A; Lo Russo, G; Miele, E; Miscusi, M; Papa, A; Petrozza, V; Spinelli, GP; Tomao, S1
Branle, F; Camby, I; Geurts-Moespot, A; Jeuken, J; Kiss, R; Lefranc, F; Salmon, I; Sprenger, S; Sweep, F1
Akdemir, H; Altinbas, M; Cihan, Y; Coskun, HS; Er, O; Kaplan, B; Karahacioglu, E; Kontas, O; Menku, A; Ozkan, M1
Kobiakov, GL1
Berille, J; Bertrand, P; Bizzari, JP; Cour, V; Gerard, B; Giroux, B; Khayat, D; Sarkany, M1
Biron, P; Evene, E; Giroux, B; Gordon, B; Lucas, C; Mornex, F; Richards, R; Roux, N; Solere, P; Tranchand, B1
Boland, I; Gouyette, A; Lacroix, C; Lellouch-Tubiana, A; Margison, GP; Morizet, J; Parker, F; Pierre-Kahn, A; Poullain, MG; Terrier-Lacombe, MJ; Vassal, G; Vénuat, AM; Watson, AJ1
Bauer, J; Biollaz, J; Buclin, T; Decosterd, LA; Gander, M; Lejeune, F; Leyvraz, S; Marzolini, C; Shen, F1
Belanich, M; Biollaz, J; Bonfanti, M; Colella, G; D'Incalci, M; Decosterd, L; Gander, M; Lejeune, F; Leyvraz, S; Liénard, D; Marzolini, C; Perey, L; Shen, F; Yarosh, D1
Frenay, M; Lebrun, C; Lonjon, M; Marcy, PY; Paquis, P1
Bourg, V; Chichmanian, RM; Frenay, M; Lebrun, C; Thomas, P1
Berger, E; Boiardi, A; Ciusani, E; Giroux, B; Lucas, C; Margison, G; Silvani, A; Watson, A1
Derlon, JM; Frenay, M; Giroux, B; Khoury, S; Namer, M1

Reviews

5 review(s) available for fotemustine and Glioma

ArticleYear
An overview of fotemustine in high-grade gliomas: from single agent to association with bevacizumab.
    BioMed research international, 2014, Volume: 2014

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Drug Therapy, Combination; Glioma; Humans; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Young Adult

2014
Nitrosoureas in the Management of Malignant Gliomas.
    Current neurology and neuroscience reports, 2016, Volume: 16, Issue:2

    Topics: Dacarbazine; Glioma; Humans; Lomustine; Nitrosourea Compounds; Organophosphorus Compounds; Procarbazine; Temozolomide; Vincristine

2016
Chemotherapy and target therapy in the management of adult high- grade gliomas.
    Current cancer drug targets, 2012, Volume: 12, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Central Nervous System Neoplasms; Cetuximab; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; ErbB Receptors; Erlotinib Hydrochloride; Glioma; Humans; Nitrosourea Compounds; Organophosphorus Compounds; Promoter Regions, Genetic; Quinazolines; Temozolomide; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins

2012
[Clinical significance of mustoforan in management of malignant glioma].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carmustine; Clinical Trials as Topic; Disease-Free Survival; Female; Glioblastoma; Glioma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; Nitrosourea Compounds; Oligodendroglioma; Organophosphorus Compounds; Semustine; Survival Analysis; Treatment Outcome

2007
Fotemustine in the treatment of brain primary tumors and metastases.
    Cancer investigation, 1994, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Glioma; Humans; Lung Neoplasms; Melanoma; Middle Aged; Multicenter Studies as Topic; Nitrosourea Compounds; Organophosphorus Compounds

1994

Trials

8 trial(s) available for fotemustine and Glioma

ArticleYear
Safety of second-line chemotherapy with non-conventional fotemustine schedule in recurrent high grade gliomas: a single institution experience.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Prognosis; Prospective Studies; Salvage Therapy; Survival Rate; Young Adult

2013
Activity and safety of bevacizumab plus fotemustine for recurrent malignant gliomas.
    BioMed research international, 2014, Volume: 2014

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Disease-Free Survival; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Survival Rate

2014
Concurrent radiotherapy: fotemustine combination for newly diagnosed malignant glioma patients, a phase II study.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Progression; Female; Glioma; Hematologic Diseases; Humans; Male; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Prospective Studies; Stereotaxic Techniques; Supratentorial Neoplasms; Survival Rate

2009
Low-dose fotemustine for recurrent malignant glioma: a multicenter phase II study.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Female; Glioma; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Promoter Regions, Genetic; Tumor Suppressor Proteins

2010
Phase I pharmacokinetics study of high-dose fotemustine and its metabolite 2-chloroethanol in patients with high-grade gliomas.
    Cancer chemotherapy and pharmacology, 1993, Volume: 32, Issue:1

    Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Ethylene Chlorohydrin; Female; Glioma; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds

1993
Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Female; Glioma; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Melanoma; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Temozolomide

1998
Sequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumours.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Glioma; Humans; Lymphocytes; Male; Melanoma; Middle Aged; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Temozolomide

1999
Fotemustine combined with procarbazine in recurrent malignant gliomas: a phase I study with evaluation of lymphocyte 06-alkylguanine-DNA alkyltransferase activity.
    Journal of neuro-oncology, 2001, Volume: 52, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Female; Glioma; Humans; Lymphocytes; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Procarbazine

2001

Other Studies

10 other study(ies) available for fotemustine and Glioma

ArticleYear
Hypofractionated stereotactic radiotherapy in combination with bevacizumab or fotemustine for patients with progressive malignant gliomas.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Female; Glioma; Humans; Karnofsky Performance Status; Male; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Radiation Dose Hypofractionation; Radiosurgery; Retrospective Studies

2015
GEINOFOTE: efficacy and safety of fotemustine in patients with high-grade recurrent gliomas and poor performance status.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2016, Volume: 18, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Female; Glioma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Retrospective Studies; Treatment Outcome; Young Adult

2016
Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation.
    BMC cancer, 2009, Mar-31, Volume: 9

    Topics: Adult; Aged; Antineoplastic Agents; DNA Methylation; Dose-Response Relationship, Drug; Follow-Up Studies; Glioma; Humans; Karnofsky Performance Status; Middle Aged; Multivariate Analysis; Nausea; Neoplasm Recurrence, Local; Neutropenia; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Promoter Regions, Genetic; Retrospective Studies; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vomiting

2009
A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy.
    Journal of translational medicine, 2012, May-14, Volume: 10

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Retrospective Studies; Risk Factors; Temozolomide; Time Factors; Treatment Failure

2012
Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy.
    Cancer, 2002, Aug-01, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromosome Deletion; Chromosomes, Human, Pair 1; Combined Modality Therapy; Dacarbazine; DNA Fingerprinting; DNA, Neoplasm; Glioma; Glutathione Transferase; Humans; Immunohistochemistry; Intermediate Filament Proteins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Neoplasms, Experimental; Nerve Tissue Proteins; Nestin; Nitrosourea Compounds; Nucleic Acid Hybridization; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Survival Analysis; Temozolomide; Treatment Outcome; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vimentin; Xenograft Model Antitumor Assays

2002
Post-operative sequential chemo-radiotherapy in high-grade cerebral gliomas with fotemustine.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:3

    Topics: Adult; Brain Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Staging; Nitrosourea Compounds; Organophosphorus Compounds; Probability; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Risk Assessment; Survival Analysis

2004
Activity of fotemustine in medulloblastoma and malignant glioma xenografts in relation to O6-alkylguanine-DNA alkyltransferase and alkylpurine-DNA N-glycosylase activity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cerebellar Neoplasms; DNA Glycosylases; DNA Repair; Drug Screening Assays, Antitumor; Female; Glioma; Humans; Male; Medulloblastoma; Mice; Middle Aged; N-Glycosyl Hydrolases; Neoplasm Transplantation; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Transplantation, Heterologous; Tumor Cells, Cultured

1998
[Chemotherapy of malignant inoperable gliomas. The association of fotemustine-cisplatine-etoposide as neoadjuvants].
    Revue neurologique, 2000, Volume: 156, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cisplatin; Etoposide; Female; Glioma; Humans; Male; Middle Aged; Neoadjuvant Therapy; Nitrosourea Compounds; Organophosphorus Compounds; Treatment Outcome

2000
Nitroso-urea-cisplatin-based chemotherapy associated with valproate: increase of haematologic toxicity.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Drug Interactions; Epilepsy; Etoposide; Female; Glioma; Hematologic Tests; Humans; Male; Middle Aged; Neutropenia; Nitrosourea Compounds; Organophosphorus Compounds; Retrospective Studies; Thrombocytopenia; Valproic Acid

2001
Phase II study of fotemustine in recurrent supratentorial malignant gliomas.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain; Drug Evaluation; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Organophosphorus Compounds; Supratentorial Neoplasms

1991