Page last updated: 2024-10-17

fosmidomycin and Tularemia

fosmidomycin has been researched along with Tularemia in 1 studies

fosmidomycin: from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source
fosmidomycin : Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.

Tularemia: A plague-like disease of rodents, transmissible to man. It is caused by FRANCISELLA TULARENSIS and is characterized by fever, chills, headache, backache, and weakness.

Research Excerpts

ExcerptRelevanceReference
"Antibiotic fosmidomycin will know as inhibitor of the nonmevalonate pathway of isoprenoid biosynthesis and as possible antimalarial drug, was shown to possess a certain protective effect on mice experimentally infected with tularemia, tiphus or coli-septicemia."3.72[Effect of fosfidomycin on development of various infections in mice]. ( Bakhteeva, IV; Biketov, SF; Biniukov, VI; Borzenkov, VN; OstrovskiÄ­, DN; Potapov, VD; Titareva, GM; Wiesner, J, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Potapov, VD1
Bakhteeva, IV1
Borzenkov, VN1
Titareva, GM1
Wiesner, J1
Biniukov, VI1
OstrovskiÄ­, DN1
Biketov, SF1

Other Studies

1 other study available for fosmidomycin and Tularemia

ArticleYear
[Effect of fosfidomycin on development of various infections in mice].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2003, Volume: 48, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Escherichia coli Infections; Fosfomycin; Mice;

2003