fosmidomycin has been researched along with Infections, Chlamydia in 1 studies
fosmidomycin: from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source
fosmidomycin : Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bactoprenol is a critical isoprenoid required for peptidoglycan precursor assembly." | 1.51 | Fosmidomycin, an inhibitor of isoprenoid synthesis, induces persistence in Chlamydia by inhibiting peptidoglycan assembly. ( Brockett, M; Liechti, GW; Maurelli, AT; Singh, R; Slade, JA, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Slade, JA | 1 |
| Brockett, M | 1 |
| Singh, R | 1 |
| Liechti, GW | 1 |
| Maurelli, AT | 1 |
1 other study available for fosmidomycin and Infections, Chlamydia
| Article | Year |
|---|---|
Fosmidomycin, an inhibitor of isoprenoid synthesis, induces persistence in Chlamydia by inhibiting peptidoglycan assembly.
Topics: Aldose-Ketose Isomerases; Anti-Bacterial Agents; Cell Line, Tumor; Chlamydia Infections; Chlamydia t | 2019 |