Page last updated: 2024-10-17

fosmidomycin and E coli Infections

fosmidomycin has been researched along with E coli Infections in 2 studies

fosmidomycin: from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source
fosmidomycin : Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.

Research Excerpts

ExcerptRelevanceReference
"Antibiotic fosmidomycin will know as inhibitor of the nonmevalonate pathway of isoprenoid biosynthesis and as possible antimalarial drug, was shown to possess a certain protective effect on mice experimentally infected with tularemia, tiphus or coli-septicemia."3.72[Effect of fosfidomycin on development of various infections in mice]. ( Bakhteeva, IV; Biketov, SF; Biniukov, VI; Borzenkov, VN; Ostrovskiĭ, DN; Potapov, VD; Titareva, GM; Wiesner, J, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tritsch, D1
Zinglé, C1
Rohmer, M1
Grosdemange-Billiard, C1
Potapov, VD1
Bakhteeva, IV1
Borzenkov, VN1
Titareva, GM1
Wiesner, J1
Biniukov, VI1
Ostrovskiĭ, DN1
Biketov, SF1

Other Studies

2 other studies available for fosmidomycin and E coli Infections

ArticleYear
Flavonoids: true or promiscuous inhibitors of enzyme? The case of deoxyxylulose phosphate reductoisomerase.
    Bioorganic chemistry, 2015, Volume: 59

    Topics: Aldose-Ketose Isomerases; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; Flavonoi

2015
[Effect of fosfidomycin on development of various infections in mice].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2003, Volume: 48, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Escherichia coli Infections; Fosfomycin; Mice;

2003