fosmidomycin has been researched along with Disease Models, Animal in 1 studies
fosmidomycin: from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source
fosmidomycin : Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The drug has been used successfully to treat malaria patients in clinical studies, thus validating IspC as an antimalarial target." | 1.42 | Prodrugs of reverse fosmidomycin analogues. ( Bacher, A; Behrendt, C; Brücher, K; Fischer, M; Gräwert, T; Held, J; Illarionov, B; Konzuch, S; Kurz, T; Lienau, C; Maes, L; Mordmüller, B; Wittlin, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brücher, K | 1 |
| Gräwert, T | 1 |
| Konzuch, S | 1 |
| Held, J | 1 |
| Lienau, C | 1 |
| Behrendt, C | 1 |
| Illarionov, B | 1 |
| Maes, L | 1 |
| Bacher, A | 1 |
| Wittlin, S | 1 |
| Mordmüller, B | 1 |
| Fischer, M | 1 |
| Kurz, T | 1 |
1 other study available for fosmidomycin and Disease Models, Animal
| Article | Year |
|---|---|
Prodrugs of reverse fosmidomycin analogues.
Topics: Animals; Antimalarials; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Fos | 2015 |