fosmidomycin has been researched along with Bacterial Disease in 5 studies
fosmidomycin: from Streptomyces lavendulae; RN given refers to parent cpd; structure in second source
fosmidomycin : Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antibiotic fosmidomycin will know as inhibitor of the nonmevalonate pathway of isoprenoid biosynthesis and as possible antimalarial drug, was shown to possess a certain protective effect on mice experimentally infected with tularemia, tiphus or coli-septicemia." | 3.72 | [Effect of fosfidomycin on development of various infections in mice]. ( Bakhteeva, IV; Biketov, SF; Biniukov, VI; Borzenkov, VN; Ostrovskiĭ, DN; Potapov, VD; Titareva, GM; Wiesner, J, 2003) |
| "The failure to treat everyday bacterial infections is a current threat as pathogens are finding new ways to thwart antibiotics through mechanisms of resistance and intracellular refuge, thus rendering current antibiotic strategies ineffective." | 2.72 | Antibiotic-cell-penetrating peptide conjugates targeting challenging drug-resistant and intracellular pathogenic bacteria. ( Chmielewski, J; Zeiders, SM, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zeiders, SM | 1 |
| Chmielewski, J | 1 |
| Murkin, AS | 1 |
| Manning, KA | 1 |
| Kholodar, SA | 1 |
| Potapov, VD | 1 |
| Bakhteeva, IV | 1 |
| Borzenkov, VN | 1 |
| Titareva, GM | 1 |
| Wiesner, J | 1 |
| Biniukov, VI | 1 |
| Ostrovskiĭ, DN | 1 |
| Biketov, SF | 1 |
| Mine, Y | 1 |
| Kamimura, T | 1 |
| Nonoyama, S | 1 |
| Nishida, M | 1 |
| Goto, S | 1 |
| Kuwahara, S | 1 |
| Poliak, MS | 1 |
3 reviews available for fosmidomycin and Bacterial Disease
| Article | Year |
|---|---|
Antibiotic-cell-penetrating peptide conjugates targeting challenging drug-resistant and intracellular pathogenic bacteria.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Infections; Cell-Penetrating Peptides; Dr | 2021 |
Mechanism and inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Topics: Aldose-Ketose Isomerases; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Disco | 2014 |
[Antibiotics of the phosphonic acid group].
Topics: Alanine; Animals; Anti-Bacterial Agents; Bacterial Infections; Dose-Response Relationship, Drug; Dru | 1987 |
2 other studies available for fosmidomycin and Bacterial Disease
| Article | Year |
|---|---|
[Effect of fosfidomycin on development of various infections in mice].
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Escherichia coli Infections; Fosfomycin; Mice; | 2003 |
In vitro and in vivo antibacterial activities of FR-31564, a new phosphonic acid antibiotic.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Culture Media; Drug Resistance, Micr | 1980 |