fosfomycin and Leprosy

fosfomycin has been researched along with Leprosy* in 1 studies

Reviews

1 review(s) available for fosfomycin and Leprosy

ArticleYear
[The control leprous peripheral neuropathy and chemotherapy].
    Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association, 1999, Volume: 68, Issue:2

    Clarithromycin(CAM), Roxithromycin(RXM), Minocycline(MINO) and Fosfomycin(FOM) has anti-inflammatory action and immunomodulatory activity, while the anti-mycobacterium leprae activity is shown. CAM and RXM suppress the rat carrageenin edema, and MINO suppresses the rat adjvant arthritis. There is the immunosuppression on adrenocorticosteroid while the inflammatory cytokine is suppressed. CAM, MINO, FOM suppresses the inflammatory cytokine, while it has the immunomodulatory activity. Fusidic acid(FA) suppresses the inflammatory cytokine with the action of being similar to cyclosporin A, and it has the immunomodulatory activity. New macrolides derivatives, CAM and RXM showed the inflammatory regulation, and MINO showed the anti-inflammatory activity with FA. The combination chemotherapy can be enforced, while peripheral neuropathy is prevented by the control of the leprosy reaction.

    Topics: Adjuvants, Immunologic; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Clarithromycin; Drug Therapy, Combination; Fosfomycin; Fusidic Acid; Humans; Leprostatic Agents; Leprosy; Minocycline; Peripheral Nervous System Diseases; Protein Synthesis Inhibitors; Rats; Roxithromycin

1999