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foscarnet and Wiskott-Aldrich Syndrome

foscarnet has been researched along with Wiskott-Aldrich Syndrome in 1 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Wiskott-Aldrich Syndrome: A rare, X-linked immunodeficiency syndrome characterized by ECZEMA; LYMPHOPENIA; and, recurrent pyogenic infection. It is seen exclusively in young boys. Typically, IMMUNOGLOBULIN M levels are low and IMMUNOGLOBULIN A and IMMUNOGLOBULIN E levels are elevated. Lymphoreticular malignancies are common.

Research Excerpts

ExcerptRelevanceReference
" The patient had a history of acyclovir (ACV)-resistant (ACV(r)) herpes simplex virus type 1 (HSV-1) infections prior to BMT."7.71Bone marrow transplantation in a child with Wiskott-Aldrich syndrome latently infected with acyclovir-resistant (ACV(r)) herpes simplex virus type 1: emergence of foscarnet-resistant virus originating from the ACV(r) virus. ( De Clercq, E; Kato, S; Kurane, I; Maeda, A; Morikawa, S; Niikura, M; Saijo, M; Suzutani, T; Yabe, H; Yasuda, Y, 2002)
" The patient had a history of acyclovir (ACV)-resistant (ACV(r)) herpes simplex virus type 1 (HSV-1) infections prior to BMT."3.71Bone marrow transplantation in a child with Wiskott-Aldrich syndrome latently infected with acyclovir-resistant (ACV(r)) herpes simplex virus type 1: emergence of foscarnet-resistant virus originating from the ACV(r) virus. ( De Clercq, E; Kato, S; Kurane, I; Maeda, A; Morikawa, S; Niikura, M; Saijo, M; Suzutani, T; Yabe, H; Yasuda, Y, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saijo, M1
Yasuda, Y1
Yabe, H1
Kato, S1
Suzutani, T1
De Clercq, E1
Niikura, M1
Maeda, A1
Kurane, I1
Morikawa, S1

Other Studies

1 other study available for foscarnet and Wiskott-Aldrich Syndrome

ArticleYear
Bone marrow transplantation in a child with Wiskott-Aldrich syndrome latently infected with acyclovir-resistant (ACV(r)) herpes simplex virus type 1: emergence of foscarnet-resistant virus originating from the ACV(r) virus.
    Journal of medical virology, 2002, Volume: 68, Issue:1

    Topics: Acyclovir; Adolescent; Animals; Antiviral Agents; Base Sequence; Bone Marrow Transplantation; Cell L

2002