Page last updated: 2024-10-27

foscarnet and Ulcer

foscarnet has been researched along with Ulcer in 21 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.

Research Excerpts

ExcerptRelevanceReference
"Foscarnet, administered via a central line, was used for the treatment of 18 episodes of cytomegalovirus (CMV) esophageal ulceration in 15 patients, and in the treatment of 27 episodes of CMV colitis in 22 patients."7.68Foscarnet in the treatment of cytomegalovirus infection of the esophagus and colon in patients with the acquired immune deficiency syndrome. ( Connolly, GM; Gazzard, BG; Hawkins, DA; Nelson, MR, 1991)
"Treatment with Foscarnet may be initially effective, but does not eliminate cytomegalovirus infection."6.66Cytomegalovirus colitis and oesophageal ulceration in the context of AIDS: clinical manifestations and preliminary report of treatment with Foscarnet (phosphonoformate). ( Barrison, I; Boylston, A; Forster, S; Jeffries, DJ; Pinching, AJ; Thom, S; Unwin, R; Weber, JN, 1987)
"Foscarnet, administered via a central line, was used for the treatment of 18 episodes of cytomegalovirus (CMV) esophageal ulceration in 15 patients, and in the treatment of 27 episodes of CMV colitis in 22 patients."3.68Foscarnet in the treatment of cytomegalovirus infection of the esophagus and colon in patients with the acquired immune deficiency syndrome. ( Connolly, GM; Gazzard, BG; Hawkins, DA; Nelson, MR, 1991)
"Treatment with Foscarnet may be initially effective, but does not eliminate cytomegalovirus infection."2.66Cytomegalovirus colitis and oesophageal ulceration in the context of AIDS: clinical manifestations and preliminary report of treatment with Foscarnet (phosphonoformate). ( Barrison, I; Boylston, A; Forster, S; Jeffries, DJ; Pinching, AJ; Thom, S; Unwin, R; Weber, JN, 1987)
"Penile ulcers are best managed by stopping the infusion until the ulcers heal; they may be prevented by paying careful attention to personal hygiene."2.40Minimising the dosage-limiting toxicities of foscarnet induction therapy. ( Jayaweera, DT, 1997)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's16 (76.19)18.2507
2000's0 (0.00)29.6817
2010's3 (14.29)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Arnold, JD1
Smith, J1
Manam, SP1
Lewis, FM1
Haouy, S1
Rocher, F1
Poirée, M1
Saint-Paul, MC1
De Smet, S1
Sirvent, A1
Sirvent, N1
Torres, T1
Fernandes, I1
Sanches, M1
Selores, M1
Aguirrebengoa, K1
González, R1
Oñate, J1
Ibáñez de Maeztu, JC1
Ruiz-Irastorza, G1
Montejo, M1
Schiff, TA1
Bodian, AB1
Buchness, MR1
Heinic, GS1
Greenspan, D1
Greenspan, JS1
Moyle, G1
Barton, S1
Gazzard, BG2
Miguélez, M1
Linares Feria, M1
Laynez, P1
Méndez, M1
Caumes, E1
Gatineau, M1
Bricaire, F1
Dohin, E1
Katlama, C1
Gentilini, M1
Len, O1
de Otero, J1
Ribera, E1
Ocaña, I1
Luelmo, J1
Sala, M1
Sasal, M1
Cervantes, M1
Jayaweera, DT1
Swetter, SM1
Hill, EL1
Kern, ER1
Koelle, DM1
Posavad, CM1
Lawrence, W1
Safrin, S1
Wald, A1
Mattson, D1
Schubert, MA1
Saint-Marc, T1
Fournier, F1
Touraine, JL1
Marneff, E1
Van der Pijl, JW2
Nelson, MR1
Connolly, GM1
Hawkins, DA1
Frissen, PH1
Reiss, P1
Hulsebosch, HJ1
Van Den Tweel, JG1
Lange, JM1
Danner, SA1
Gilquin, J1
Weiss, L1
Kazatchkine, MD1
Weber, JN1
Thom, S1
Barrison, I1
Unwin, R1
Forster, S1
Jeffries, DJ1
Boylston, A1
Pinching, AJ1

Reviews

2 reviews available for foscarnet and Ulcer

ArticleYear
Oral CMV lesions and the HIV infected. Early recognition can help prevent morbidity.
    Journal of the American Dental Association (1939), 1993, Volume: 124, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Ganciclovir; HIV Infec

1993
Minimising the dosage-limiting toxicities of foscarnet induction therapy.
    Drug safety, 1997, Volume: 16, Issue:4

    Topics: Animals; Antiviral Agents; Cytomegalovirus Infections; Dose-Response Relationship, Drug; Female; Fos

1997

Trials

1 trial available for foscarnet and Ulcer

ArticleYear
Cytomegalovirus colitis and oesophageal ulceration in the context of AIDS: clinical manifestations and preliminary report of treatment with Foscarnet (phosphonoformate).
    Gut, 1987, Volume: 28, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Clinical Trials as Topic; Colitis; Cytomegalovirus Infect

1987

Other Studies

18 other studies available for foscarnet and Ulcer

ArticleYear
Foscarnet-Induced Penile Ulceration.
    JAMA dermatology, 2023, 10-01, Volume: 159, Issue:10

    Topics: Antiviral Agents; Foscarnet; Humans; Male; Penile Diseases; Penis; Skin Diseases; Ulcer

2023
Superficial ulceration on the vulva.
    Cutis, 2017, Volume: 99, Issue:1

    Topics: Antiviral Agents; Female; Foscarnet; Humans; Ulcer; Vulvar Diseases; Young Adult

2017
Isolated esophageal ulcerations in immunocompromised patients: mycophenolate mofetil or foscarnet, who is guilty?
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:8

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cytomegalovirus Infections; E

2011
Foscarnet-induced penile ulceration.
    Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2011, Volume: 20, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Foscarnet; Humans; Male; Penile Disease

2011
[Foscarnet related vulvar ulcers. Description of 2 AIDS patients].
    Enfermedades infecciosas y microbiologia clinica, 1995, Volume: 13, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Female; Foscarnet; Humans; Ulcer; Vulvar Diseases

1995
Foscarnet-induced penile ulceration.
    International journal of dermatology, 1993, Volume: 32, Issue:7

    Topics: Adult; Foscarnet; Humans; Male; Penile Diseases; Ulcer

1993
Penile ulceration with foscarnet therapy.
    AIDS (London, England), 1993, Volume: 7, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Humans; Male; Penile D

1993
[Foscarnet and genital lesions].
    Medicina clinica, 1993, May-08, Volume: 100, Issue:18

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Humans; Male; P

1993
Foscarnet-induced vulvar erosion.
    Journal of the American Academy of Dermatology, 1993, Volume: 28, Issue:5 Pt 1

    Topics: Adult; Female; Foscarnet; HIV Infections; Humans; Retinal Necrosis Syndrome, Acute; Ulcer; Vulvar Di

1993
[Ulcer in the urethral meatus and HIV infection].
    Enfermedades infecciosas y microbiologia clinica, 1995, Volume: 13, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Drug Eru

1995
[Genital ulcers from foscarnet: three cases].
    Medicina clinica, 1996, Sep-14, Volume: 107, Issue:8

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Genital Diseases, Male; Humans; Male; Ulcer

1996
Chronic vulvar ulceration in an immunocompetent woman due to acyclovir-resistant, thymidine kinase-deficient herpes simplex virus.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:3

    Topics: Acyclovir; Antiviral Agents; Chronic Disease; Drug Resistance, Microbial; Female; Foscarnet; Humans;

1998
Photo quiz. Foscarnet-induced genital ulcers.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 28, Issue:1

    Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Female; Foscarnet; Genital Diseases,

1999
Uvula and oesophageal ulcerations with foscarnet.
    Lancet (London, England), 1992, Oct-17, Volume: 340, Issue:8825

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Esophagus; Foscarnet; Huma

1992
[Prevention of genital ulcerations during treatment with foscarnet].
    Presse medicale (Paris, France : 1983), 1992, Feb-29, Volume: 21, Issue:8

    Topics: Antiviral Agents; Female; Foscarnet; Genital Diseases, Female; Genital Diseases, Male; Humans; Male;

1992
Foscarnet in the treatment of cytomegalovirus infection of the esophagus and colon in patients with the acquired immune deficiency syndrome.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Colitis; Cytomegalovirus Infections; Es

1991
Foscarnet and penile ulceration.
    Lancet (London, England), 1990, Feb-03, Volume: 335, Issue:8684

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Herpes

1990
Genital and oral erosions induced by foscarnet.
    Lancet (London, England), 1990, Feb-03, Volume: 335, Issue:8684

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Foscarnet; Genital Diseases, Male; Huma

1990