Page last updated: 2024-10-27

foscarnet and Thrombopenia

foscarnet has been researched along with Thrombopenia in 3 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Research Excerpts

ExcerptRelevanceReference
"Foscarnet is a reasonable first line anti CMV agent in this setting."6.46CMV-related thrombocytopenia treated with foscarnet: a case series and review of the literature. ( Chajek-Shaul, T; Hershcovici, T; Koslowsky, B; Wolf, D; Yaari, S, 2010)
"During study treatment, severe neutropenia (< 0."2.70Randomized multicenter trial of foscarnet versus ganciclovir for preemptive therapy of cytomegalovirus infection after allogeneic stem cell transplantation. ( Cordonnier, C; Einsele, H; Engelhard, D; Finke, J; Lee, J; Link, H; Ljungman, P; Reusser, P; Rovira, M; Volin, L, 2002)
"Foscarnet is a reasonable first line anti CMV agent in this setting."2.46CMV-related thrombocytopenia treated with foscarnet: a case series and review of the literature. ( Chajek-Shaul, T; Hershcovici, T; Koslowsky, B; Wolf, D; Yaari, S, 2010)
"Neutropenia was the most frequent and serious side-effect of ganciclovir, 76% patients having neutrophil counts less than 1."1.28Cytomegalovirus infection in AIDS. Patterns of disease, response to therapy and trends in survival. ( Anderson, S; Beck, EJ; Coker, R; Coleman, D; Harris, JR; Main, J; Migdal, C; Peters, BS; Pinching, AJ, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yaari, S1
Koslowsky, B1
Wolf, D1
Chajek-Shaul, T1
Hershcovici, T1
Reusser, P1
Einsele, H1
Lee, J1
Volin, L1
Rovira, M1
Engelhard, D1
Finke, J1
Cordonnier, C1
Link, H1
Ljungman, P1
Peters, BS1
Beck, EJ1
Anderson, S1
Coleman, D1
Coker, R1
Main, J1
Migdal, C1
Harris, JR1
Pinching, AJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II, Multicentric, Prospective and Opened Clinical Trial of Advance Valganciclovir Treatment of CMV in Allogenic Hematopoietic Progenitors Transplant[NCT00386412]Phase 2132 participants (Anticipated)Interventional2005-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for foscarnet and Thrombopenia

ArticleYear
CMV-related thrombocytopenia treated with foscarnet: a case series and review of the literature.
    Platelets, 2010, Volume: 21, Issue:6

    Topics: Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Therapy, Combination; Fem

2010

Trials

1 trial available for foscarnet and Thrombopenia

ArticleYear
Randomized multicenter trial of foscarnet versus ganciclovir for preemptive therapy of cytomegalovirus infection after allogeneic stem cell transplantation.
    Blood, 2002, Feb-15, Volume: 99, Issue:4

    Topics: Adolescent; Adult; Antiviral Agents; Child; Cytomegalovirus Infections; Disease-Free Survival; Drug

2002

Other Studies

1 other study available for foscarnet and Thrombopenia

ArticleYear
Cytomegalovirus infection in AIDS. Patterns of disease, response to therapy and trends in survival.
    The Journal of infection, 1991, Volume: 23, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Colitis; Cytomegalovirus Infections; Female; F

1991