Page last updated: 2024-10-27

foscarnet and Skin Ulcer

foscarnet has been researched along with Skin Ulcer in 10 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Skin Ulcer: An ULCER of the skin and underlying tissues.

Research Excerpts

ExcerptRelevanceReference
"The efficacy and toxicity of foscarnet cream for the treatment of mucocutaneous herpes simplex virus lesions or lesions that were clinically unresponsive to systemic acyclovir treatment (median, 30."9.09Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study. ( Bryson, Y; Grafford, K; Hardy, WD; Javaly, K; Kalayjian, R; Klein, T; Martin-Munley, S; Wohlfeiler, M, 1999)
"Acyclovir-resistant herpes simplex virus (HSV) infection is common in immunocompromised patients, but the course of such infection is little known."7.80Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection. ( Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D, 2014)
"The efficacy and toxicity of foscarnet cream for the treatment of mucocutaneous herpes simplex virus lesions or lesions that were clinically unresponsive to systemic acyclovir treatment (median, 30."5.09Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study. ( Bryson, Y; Grafford, K; Hardy, WD; Javaly, K; Kalayjian, R; Klein, T; Martin-Munley, S; Wohlfeiler, M, 1999)
"Acyclovir-resistant herpes simplex virus (HSV) infection is common in immunocompromised patients, but the course of such infection is little known."3.80Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection. ( Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D, 2014)
"We describe a 28-year-old HIV-infected woman with AIDS, defined by cerebral toxoplasmosis and a CD4-count of less than 10 x 10(6) cells/I, who, after several eruptions of genital herpes and typical dermatomal herpes zoster, all successfully treated with acyclovir, developed chronic cutaneous ulcerating lesions on a finger and on the tibia."3.69Chronic ulcerating acyclovir-resistant varicella zoster lesions in an AIDS patient. ( Bernhard, P; Obel, N, 1995)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (90.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seang, S1
Boutolleau, D1
Burrel, S1
Regnier, S1
Epelboin, L1
Voujon, D1
Valantin, MA1
Katlama, C1
Agut, H1
Caumes, E1
Fitzgerald, E1
Goldman, HM1
Miller, WG1
Purcell, SM1
Gross, AS1
Dretler, RH1
Bernhard, P1
Obel, N1
Papini, M1
Bruni, PL1
Pechère, M1
Wunderli, W1
Trellu-Toutous, L1
Harms, M1
Saura, JH1
Krischer, J1
Javaly, K1
Wohlfeiler, M1
Kalayjian, R1
Klein, T1
Bryson, Y1
Grafford, K1
Martin-Munley, S1
Hardy, WD1
Evans, LM1
Grossman, ME1
Lacey, HB1
Ness, A1
Mandal, BK1

Reviews

1 review available for foscarnet and Skin Ulcer

ArticleYear
Foscarnet-induced penile ulcer.
    Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Foscarnet;

1992

Trials

1 trial available for foscarnet and Skin Ulcer

ArticleYear
Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study.
    Journal of acquired immune deficiency syndromes (1999), 1999, Aug-01, Volume: 21, Issue:4

    Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1999

Other Studies

8 other studies available for foscarnet and Skin Ulcer

ArticleYear
Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:9

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug

2014
A penile ulceration in a patient with the acquired immunodeficiency syndrome. Foscarnet-induced penile ulceration.
    Archives of dermatology, 1995, Volume: 131, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; H

1995
Foscarnet-induced penile ulcer in an uncircumcised patient with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 17, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Foscarnet; Humans; Male; Penile Diseases; Skin Ulcer

1993
Chronic ulcerating acyclovir-resistant varicella zoster lesions in an AIDS patient.
    Scandinavian journal of infectious diseases, 1995, Volume: 27, Issue:6

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Chronic Disease; Drug Res

1995
[A case for diagnosis: penile ulcer induced by foscarnet].
    Annales de dermatologie et de venereologie, 1996, Volume: 123, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Foscarnet; Humans; In Vitro Techniques;

1996
Treatment of acyclovir-resistant herpetic ulceration with topical foscarnet and antiviral sensitivity analysis.
    Dermatology (Basel, Switzerland), 1998, Volume: 197, Issue:3

    Topics: Acyclovir; Administration, Topical; Antiviral Agents; Drug Resistance, Microbial; Female; Foscarnet;

1998
Vulval ulceration associated with foscarnet.
    Genitourinary medicine, 1992, Volume: 68, Issue:3

    Topics: Adult; Antiviral Agents; Female; Foscarnet; Humans; Phosphonoacetic Acid; Skin Ulcer; Vulvar Disease

1992
Penile ulcerations with foscarnet.
    Lancet (London, England), 1990, Mar-03, Volume: 335, Issue:8688

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Foscarnet;

1990