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foscarnet and Skin Diseases, Viral

foscarnet has been researched along with Skin Diseases, Viral in 9 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Skin Diseases, Viral: Skin diseases caused by viruses.

Research Excerpts

ExcerptRelevanceReference
"Acyclovir-resistant herpes simplex virus (HSV) infection is common in immunocompromised patients, but the course of such infection is little known."7.80Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection. ( Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D, 2014)
"The topical efficacies of foscarnet and acyclovir incorporated into a polyoxypropylene-polyoxyethylene polymer were evaluated and compared to that of 5% acyclovir ointment (Zovirax) by use of a murine model of cutaneous herpes simplex virus type 1 infection."7.70Efficacies of topical formulations of foscarnet and acyclovir and of 5-percent acyclovir ointment (Zovirax) in a murine model of cutaneous herpes simplex virus type 1 infection. ( Bergeron, MG; Désormeaux, A; Gourde, P; Juhász, J; Piret, J, 2000)
"The influence of sodium lauryl sulfate (SLS) on the efficacies of topical gel formulations of foscarnet against herpes simplex virus type 1 (HSV-1) cutaneous infection has been evaluated in mice."7.70Sodium lauryl sulfate increases the efficacy of a topical formulation of foscarnet against herpes simplex virus type 1 cutaneous lesions in mice. ( Bergeron, MG; Cormier, H; Désormeaux, A; Gourde, P; Juhász, J; Lamontagne, J; Piret, J, 2000)
" One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to acyclovir and was intolerant of foscarnet."7.69Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). ( Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G, 1994)
"Acyclovir-resistant herpes simplex virus (HSV) infection is common in immunocompromised patients, but the course of such infection is little known."3.80Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection. ( Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D, 2014)
"The topical efficacies of foscarnet and acyclovir incorporated into a polyoxypropylene-polyoxyethylene polymer were evaluated and compared to that of 5% acyclovir ointment (Zovirax) by use of a murine model of cutaneous herpes simplex virus type 1 infection."3.70Efficacies of topical formulations of foscarnet and acyclovir and of 5-percent acyclovir ointment (Zovirax) in a murine model of cutaneous herpes simplex virus type 1 infection. ( Bergeron, MG; Désormeaux, A; Gourde, P; Juhász, J; Piret, J, 2000)
"The influence of sodium lauryl sulfate (SLS) on the efficacies of topical gel formulations of foscarnet against herpes simplex virus type 1 (HSV-1) cutaneous infection has been evaluated in mice."3.70Sodium lauryl sulfate increases the efficacy of a topical formulation of foscarnet against herpes simplex virus type 1 cutaneous lesions in mice. ( Bergeron, MG; Cormier, H; Désormeaux, A; Gourde, P; Juhász, J; Lamontagne, J; Piret, J, 2000)
" One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to acyclovir and was intolerant of foscarnet."3.69Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). ( Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G, 1994)
"A treatment with foscarnet was administered and clinical improvement was observed as early as the fourth day, with complete reepithelialization 50 days later."1.29[Chronic herpes resistant to acyclovir in a patient with AIDS]. ( About, I; Bernard, P; Capdeville, J; Massip, P, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's4 (44.44)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seang, S1
Boutolleau, D1
Burrel, S1
Regnier, S1
Epelboin, L1
Voujon, D1
Valantin, MA1
Katlama, C1
Agut, H1
Caumes, E1
Brown, TJ1
McCrary, M1
Tyring, SK1
Tan, HH1
Goh, CL1
About, I1
Capdeville, J1
Bernard, P1
Massip, P1
Snoeck, R2
Andrei, G1
Gérard, M1
Silverman, A1
Hedderman, A1
Balzarini, J1
Sadzot-Delvaux, C1
Tricot, G1
Clumeck, N1
De Clercq, E1
Lee, MS1
Cooney, EL1
Stoessel, KM1
Gariano, RF1
Nikkels, AF1
Rentier, B1
Pierard, GE1
Piret, J2
Désormeaux, A2
Gourde, P2
Juhász, J2
Bergeron, MG2
Cormier, H1
Lamontagne, J1

Reviews

3 reviews available for foscarnet and Skin Diseases, Viral

ArticleYear
Antiviral agents: Non-antiretroviral [correction of Nonantiviral] drugs.
    Journal of the American Academy of Dermatology, 2002, Volume: 47, Issue:4

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Chickenpox; Cytomegalovirus Infections; Famciclovir; Fos

2002
Viral infections affecting the skin in organ transplant recipients: epidemiology and current management strategies.
    American journal of clinical dermatology, 2006, Volume: 7, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Ad

2006
Chronic verrucous varicella zoster virus skin lesions: clinical, histological, molecular and therapeutic aspects.
    Clinical and experimental dermatology, 1999, Volume: 24, Issue:5

    Topics: Acyclovir; Antiviral Agents; Drug Resistance, Microbial; Foscarnet; Herpesvirus 3, Human; HIV Infect

1999

Other Studies

6 other studies available for foscarnet and Skin Diseases, Viral

ArticleYear
Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:9

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug

2014
[Chronic herpes resistant to acyclovir in a patient with AIDS].
    Annales de dermatologie et de venereologie, 1994, Volume: 121, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Buttocks; Chronic Disease; Drug Resistance; Fo

1994
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4

    Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1994
Varicella zoster virus retrobulbar optic neuritis preceding retinitis in patients with acquired immune deficiency syndrome.
    Ophthalmology, 1998, Volume: 105, Issue:3

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cerebrospinal Fluid; Fema

1998
Efficacies of topical formulations of foscarnet and acyclovir and of 5-percent acyclovir ointment (Zovirax) in a murine model of cutaneous herpes simplex virus type 1 infection.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:1

    Topics: Acyclovir; Administration, Topical; Animals; Drug Administration Schedule; Female; Foscarnet; Herpes

2000
Sodium lauryl sulfate increases the efficacy of a topical formulation of foscarnet against herpes simplex virus type 1 cutaneous lesions in mice.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:9

    Topics: Administration, Topical; Animals; Antiviral Agents; Cell Survival; Chemistry, Pharmaceutical; Chloro

2000