foscarnet has been researched along with Renal Insufficiency in 5 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although foscarnet is a promising alternative for the treatment of cytomegalovirus (CMV) infection, its toxicity can be significant in patients with advanced age." | 7.74 | Reduced dose of foscarnet as preemptive therapy for cytomegalovirus infection following reduced-intensity cord blood transplantation. ( Hori, A; Kami, M; Kato, D; Kusumi, E; Masuoka, K; Matsumura, T; Miyakoshi, S; Morinaga, S; Murashige, N; Narimatsu, H; Shibata, T; Taniguchi, S; Wake, A; Yuji, K, 2007) |
| "Foscarnet was discontinued due to progressive renal insufficiency in all three patients (days 11, 19, and 21)." | 5.07 | A dose escalation study to determine the toxicity and maximally tolerated dose of foscarnet. ( Koenig, S; Polis, MA; Seidel, EA, 1993) |
| "Although foscarnet is a promising alternative for the treatment of cytomegalovirus (CMV) infection, its toxicity can be significant in patients with advanced age." | 3.74 | Reduced dose of foscarnet as preemptive therapy for cytomegalovirus infection following reduced-intensity cord blood transplantation. ( Hori, A; Kami, M; Kato, D; Kusumi, E; Masuoka, K; Matsumura, T; Miyakoshi, S; Morinaga, S; Murashige, N; Narimatsu, H; Shibata, T; Taniguchi, S; Wake, A; Yuji, K, 2007) |
| "Three acquired immune deficiency syndrome patients given foscarnet to treat cytomegalovirus retinitis developed renal failure with crystal deposits within the renal glomeruli." | 3.70 | Identification of crystals in kidneys of AIDS patients treated with foscarnet. ( Beaufils, H; Daudon, M; Jouanneau, C; Katlama, C; Lacour, B; Maurice-Estepa, L; Sazdovitch, V, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ota, R | 1 |
| Hirata, A | 1 |
| Narimatsu, H | 1 |
| Kami, M | 1 |
| Kato, D | 1 |
| Matsumura, T | 1 |
| Murashige, N | 1 |
| Kusumi, E | 1 |
| Yuji, K | 1 |
| Hori, A | 1 |
| Shibata, T | 1 |
| Masuoka, K | 1 |
| Wake, A | 1 |
| Miyakoshi, S | 1 |
| Morinaga, S | 1 |
| Taniguchi, S | 1 |
| Seidel, EA | 1 |
| Koenig, S | 1 |
| Polis, MA | 1 |
| Zaman, MM | 1 |
| Burney, S | 1 |
| Landman, D | 1 |
| Quale, JM | 1 |
| Maurice-Estepa, L | 1 |
| Daudon, M | 1 |
| Katlama, C | 1 |
| Jouanneau, C | 1 |
| Sazdovitch, V | 1 |
| Lacour, B | 1 |
| Beaufils, H | 1 |
1 trial available for foscarnet and Renal Insufficiency
| Article | Year |
|---|---|
A dose escalation study to determine the toxicity and maximally tolerated dose of foscarnet.
Topics: Acquired Immunodeficiency Syndrome; Adult; Creatinine; Dose-Response Relationship, Drug; Foscarnet; | 1993 |
4 other studies available for foscarnet and Renal Insufficiency
| Article | Year |
|---|---|
Relationship between renal dysfunction and electrolyte abnormalities in hematopoietic stem cell transplant patients treated with foscarnet.
Topics: Adult; Aged; Antiviral Agents; Creatinine; Cytomegalovirus Infections; Electrolytes; Female; Foscarn | 2021 |
Reduced dose of foscarnet as preemptive therapy for cytomegalovirus infection following reduced-intensity cord blood transplantation.
Topics: Adolescent; Adult; Aged; Antigens, Viral; Antiviral Agents; Cord Blood Stem Cell Transplantation; Cy | 2007 |
Rapid development of renal insufficiency with the simultaneous administration of amphotericin B and foscarnet.
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiviral Agents; C | 1996 |
Identification of crystals in kidneys of AIDS patients treated with foscarnet.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; | 1998 |