Page last updated: 2024-10-27

foscarnet and Optic Neuritis

foscarnet has been researched along with Optic Neuritis in 8 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).

Research Excerpts

ExcerptRelevanceReference
" Although he was given enough antiviral treatment against CMV and immunosuppression with high-dose methylprednisolone, the patient's vision showed no improvement, and he has almost total bilateral blindness."3.78Presumed cytomegalovirus-associated retrobulbar optic neuritis in a patient after allogeneic stem cell transplantation. ( Huang, Y; Pan, S; Wang, H; Wang, Z; Yan, H; Zheng, X, 2012)
"The first is the acute retinal necrosis syndrome, which also may be seen in immunocompetent hosts."2.41Aseptic meningitis and optic neuritis preceding varicella-zoster progressive outer retinal necrosis in a patient with AIDS. ( Bellehemeur, T; DiazGranados, C; Franco-Paredes, C; Merchant, A; Rimland, D; Sanghi, P, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rothman, AL1
Walter, SD1
Zheng, X1
Huang, Y1
Wang, Z1
Yan, H1
Pan, S1
Wang, H1
Benz, MS1
Glaser, JS1
Davis, JL1
Nakamoto, BK1
Dorotheo, EU1
Biousse, V1
Tang, RA1
Schiffman, JS1
Newman, NJ1
Patel, SS1
Rutzen, AR1
Marx, JL1
Thach, AB1
Chong, LP1
Rao, NA1
Lee, MS1
Cooney, EL1
Stoessel, KM1
Gariano, RF1
Meenken, C1
van den Horn, GJ1
de Smet, MD1
van der Meer, JT1
Franco-Paredes, C1
Bellehemeur, T1
Merchant, A1
Sanghi, P1
DiazGranados, C1
Rimland, D1

Reviews

2 reviews available for foscarnet and Optic Neuritis

ArticleYear
Progressive outer retinal necrosis presenting with isolated optic neuropathy.
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infection

2004
Aseptic meningitis and optic neuritis preceding varicella-zoster progressive outer retinal necrosis in a patient with AIDS.
    AIDS (London, England), 2002, May-03, Volume: 16, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Ant

2002

Other Studies

6 other studies available for foscarnet and Optic Neuritis

ArticleYear
Optic Nerve Swelling in a Patient With Cancer.
    JAMA ophthalmology, 2018, 10-01, Volume: 136, Issue:10

    Topics: Antiviral Agents; Aqueous Humor; Cytomegalovirus; Cytomegalovirus Retinitis; Diagnosis, Differential

2018
Presumed cytomegalovirus-associated retrobulbar optic neuritis in a patient after allogeneic stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2012, Volume: 14, Issue:2

    Topics: Adult; Antiviral Agents; Blindness; Cytomegalovirus Infections; Foscarnet; Humans; Immunosuppressive

2012
Progressive outer retinal necrosis in immunocompetent patients treated initially for optic neuropathy with systemic corticosteroids.
    American journal of ophthalmology, 2003, Volume: 135, Issue:4

    Topics: Acyclovir; Aged; Antiviral Agents; Aqueous Humor; Blindness; DNA, Viral; Drug Therapy, Combination;

2003
Cytomegalovirus papillitis in patients with acquired immune deficiency syndrome. Visual prognosis of patients treated with ganciclovir and/or foscarnet.
    Ophthalmology, 1996, Volume: 103, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Cytomega

1996
Varicella zoster virus retrobulbar optic neuritis preceding retinitis in patients with acquired immune deficiency syndrome.
    Ophthalmology, 1998, Volume: 105, Issue:3

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cerebrospinal Fluid; Fema

1998
Optic neuritis heralding varicella zoster virus retinitis in a patient with acquired immunodeficiency syndrome.
    Annals of neurology, 1998, Volume: 43, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antivir

1998