foscarnet has been researched along with Nervous System Diseases in 5 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The herpesvirus DNA polymerase inhibitor foscarnet, applied topically, and the anti-herpesvirus guanosine analogue buciclovir, given orally, decreased virus replication and disease development in primary skin infections of mice caused by herpes simplex virus type 1 (HSV-1)." | 3.67 | Limited efficacy of inhibitors of herpes simplex virus DNA synthesis in murine models of recrudescent disease. ( Datema, R; Ericson, AC; Kristofferson, A; Sohl-Akerlund, A, 1988) |
| "The initial and maintenance treatment of CMV retinitis must be individualized based on the characteristics of the lesions, including location and extent, specific patient factors, and characteristics of available therapies among others." | 1.30 | Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA. ( Benson, CA; Deutsch, TA; Dieterich, DT; Drew, WL; Feinberg, J; Friedberg, DN; Griffiths, PD; Hardy, WD; Holland, GN; Jabs, DA; Jacobson, MA; Kessler, HA; Polis, MA; Powderly, WG; Spector, SA; Walmsley, S; Whitley, RJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Svennerholm, B | 1 |
| Ziegler, R | 1 |
| Lycke, E | 1 |
| Roullet, E | 1 |
| Assuerus, V | 1 |
| Gozlan, J | 1 |
| Ropert, A | 1 |
| Saïd, G | 1 |
| Baudrimont, M | 1 |
| el Amrani, M | 1 |
| Jacomet, C | 1 |
| Duvivier, C | 1 |
| Gonzales-Canali, G | 1 |
| Whitley, RJ | 1 |
| Jacobson, MA | 1 |
| Friedberg, DN | 1 |
| Holland, GN | 1 |
| Jabs, DA | 1 |
| Dieterich, DT | 1 |
| Hardy, WD | 1 |
| Polis, MA | 1 |
| Deutsch, TA | 1 |
| Feinberg, J | 1 |
| Spector, SA | 1 |
| Walmsley, S | 1 |
| Drew, WL | 1 |
| Powderly, WG | 1 |
| Griffiths, PD | 1 |
| Benson, CA | 1 |
| Kessler, HA | 1 |
| Manji, H | 1 |
| Malin, A | 1 |
| Connolly, S | 1 |
| Kristofferson, A | 1 |
| Ericson, AC | 1 |
| Sohl-Akerlund, A | 1 |
| Datema, R | 1 |
5 other studies available for foscarnet and Nervous System Diseases
| Article | Year |
|---|---|
Neuritic uptake and transport of antiviral drugs modifying herpes simplex virus infection of rat sensory neurons.
Topics: Acyclovir; Animals; Antigens, Viral; Biological Transport; Cells, Cultured; Female; Foscarnet; Gangl | 1984 |
Cytomegalovirus multifocal neuropathy in AIDS: analysis of 15 consecutive cases.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; | 1994 |
Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus | 1998 |
CMV polyradiculopathy in AIDS--suggestions for new strategies in treatment.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus Infections; Foscarnet; Humans; Male; Nerv | 1992 |
Limited efficacy of inhibitors of herpes simplex virus DNA synthesis in murine models of recrudescent disease.
Topics: Acyclovir; Administration, Oral; Administration, Topical; Animals; Antiviral Agents; Disease Models, | 1988 |