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foscarnet and Necrosis

foscarnet has been researched along with Necrosis in 12 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"To report the use of intravenous (IV) antiviral agents and intravitreal ganciclovir injections in three immunocompetent patients with severe acute retinal necrosis (ARN)."7.72Successful treatment with combination of systemic antiviral drugs and intravitreal ganciclovir injections in the management of severe necrotizing herpetic retinitis. ( Bodaghi, B; Cassoux, N; Chau Tran, TH; Lehoang, P, 2003)
"To report the use of intravenous (IV) antiviral agents and intravitreal ganciclovir injections in three immunocompetent patients with severe acute retinal necrosis (ARN)."3.72Successful treatment with combination of systemic antiviral drugs and intravitreal ganciclovir injections in the management of severe necrotizing herpetic retinitis. ( Bodaghi, B; Cassoux, N; Chau Tran, TH; Lehoang, P, 2003)
"Sera obtained from AIDS patients with cytomegalovirus (CMV) retinitis before and after treatment with foscarnet, AIDS patients with human immunodeficiency virus (HIV) retinopathy, AIDS patients without retinal disease, and normal healthy controls with and without positive CMV serologies were assayed for the presence of antibodies against the 200-kDa outer, 160-kDa middle, and 68-kDa core subunits of the neurofilament triplet."1.29Antineurofilament and antiretinal antibodies in AIDS patients with cytomegalovirus retinitis. ( Cunningham-Rundles, S; Heinemann, MH; Klein, RF; Polsky, B; Rosberger, DF; Tshering, SL, 1994)
" Slit-lamp biomicroscopy revealed no toxic effects for any of the treated eyes."1.29Ocular toxicity of iontophoretic foscarnet in rabbits. ( Equi, RA; Lee, DA; Sarraf, DA; Verdon, W; Yoshizumi, MO, 1995)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's5 (41.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schneider, EW1
Elner, SG1
van Kuijk, FJ1
Goldberg, N1
Lieberman, RM1
Eliott, D1
Johnson, MW1
Okada, S1
Kiyama, T1
Sato, E1
Tanaka, Y1
Oizumi, T1
Kuroishi, T1
Takahashi, T1
Sasaki, K1
Sugawara, S1
Endo, Y1
Ridha, E1
Cookson, H1
Devitt, E1
Nelson, M1
Rapp, P1
Pilon, F1
Chiambaretta, F1
Ménérath, JM1
Jacomet, C1
Chau Tran, TH1
Cassoux, N1
Bodaghi, B1
Lehoang, P1
Demols, P1
Claes, CA1
Farber, CM1
Rasquin, F1
Nakamoto, BK1
Dorotheo, EU1
Biousse, V1
Tang, RA1
Schiffman, JS1
Newman, NJ1
Rosberger, DF1
Tshering, SL1
Polsky, B1
Heinemann, MH1
Klein, RF1
Cunningham-Rundles, S1
Yoshizumi, MO1
Lee, DA1
Sarraf, DA1
Equi, RA1
Verdon, W1
Sanz Moreno, J1
López-Rubio, M1
Calero-García, MA1
Ratia-Jiménez, T1
Arranz-Caso, A1
Martínez-Martínez, J1
Domingo Gordo, B1
Luezas Morcuende, JJ1
Vidal Fernández, P1
Aparicio Hernández-Lastras, MJ1
Suárez Leoz, M1
Ulbricht, A1
Färber, I1
Wutzler, P1

Reviews

1 review available for foscarnet and Necrosis

ArticleYear
Progressive outer retinal necrosis presenting with isolated optic neuropathy.
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infection

2004

Other Studies

11 other studies available for foscarnet and Necrosis

ArticleYear
Chronic retinal necrosis: cytomegalovirus necrotizing retinitis associated with panretinal vasculopathy in non-HIV patients.
    Retina (Philadelphia, Pa.), 2013, Volume: 33, Issue:9

    Topics: Aged; Aged, 80 and over; Antiviral Agents; Aqueous Humor; CD4 Lymphocyte Count; Chronic Disease; Cyt

2013
Inhibition of phosphate transporters ameliorates the inflammatory and necrotic side effects of the nitrogen-containing bisphosphonate zoledronate in mice.
    The Tohoku journal of experimental medicine, 2013, Volume: 231, Issue:2

    Topics: Animals; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Foscarnet; Imidazo

2013
Febrile neutropenia in a HIV positive individual post-chemotherapy.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, Volume: 48, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cyclophosphamide; Cytomegalovirus

2010
[Bilateral uveitis with definitive hypotony caused by systemic cidofovir].
    Journal francais d'ophtalmologie, 2003, Volume: 26, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine;

2003
Successful treatment with combination of systemic antiviral drugs and intravitreal ganciclovir injections in the management of severe necrotizing herpetic retinitis.
    Ocular immunology and inflammation, 2003, Volume: 11, Issue:2

    Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Foscarnet; Gancic

2003
Macular CMV retinitis: a case report.
    Bulletin de la Societe belge d'ophtalmologie, 2004, Issue:293

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Fatal Out

2004
Antineurofilament and antiretinal antibodies in AIDS patients with cytomegalovirus retinitis.
    Clinical and diagnostic laboratory immunology, 1994, Volume: 1, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antibodies; Antiviral Agents; Cytomegalovirus Retinitis; Foscarn

1994
Ocular toxicity of iontophoretic foscarnet in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Summer, Volume: 11, Issue:2

    Topics: Animals; Antiviral Agents; Choroid; Electroretinography; Foscarnet; Iontophoresis; Microscopy, Elect

1995
Acute abdomen and intestinal necrosis produced by varicella-zoster virus in an immunocompromised host.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:5

    Topics: Abdomen, Acute; Aged; Antiviral Agents; Chickenpox; Fatal Outcome; Female; Foscarnet; Herpesvirus 3,

1996
[Bilateral acute retinal necrosis due to herpes simplex virus in inmunocompetent people and acyclovir resistance].
    Archivos de la Sociedad Espanola de Oftalmologia, 2002, Volume: 77, Issue:6

    Topics: Acute Disease; Acyclovir; Adult; Antiviral Agents; Diagnosis, Differential; Drug Therapy, Combinatio

2002
Herpes simplex virus hepatitis in mice: effects of treatment with trisodium phosphonoformate.
    Acta virologica, 1985, Volume: 29, Issue:6

    Topics: Animals; Antiviral Agents; Disease Models, Animal; Foscarnet; Hepatitis, Viral, Animal; Herpes Simpl

1985