foscarnet has been researched along with Necrosis in 12 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report the use of intravenous (IV) antiviral agents and intravitreal ganciclovir injections in three immunocompetent patients with severe acute retinal necrosis (ARN)." | 7.72 | Successful treatment with combination of systemic antiviral drugs and intravitreal ganciclovir injections in the management of severe necrotizing herpetic retinitis. ( Bodaghi, B; Cassoux, N; Chau Tran, TH; Lehoang, P, 2003) |
| "To report the use of intravenous (IV) antiviral agents and intravitreal ganciclovir injections in three immunocompetent patients with severe acute retinal necrosis (ARN)." | 3.72 | Successful treatment with combination of systemic antiviral drugs and intravitreal ganciclovir injections in the management of severe necrotizing herpetic retinitis. ( Bodaghi, B; Cassoux, N; Chau Tran, TH; Lehoang, P, 2003) |
| "Sera obtained from AIDS patients with cytomegalovirus (CMV) retinitis before and after treatment with foscarnet, AIDS patients with human immunodeficiency virus (HIV) retinopathy, AIDS patients without retinal disease, and normal healthy controls with and without positive CMV serologies were assayed for the presence of antibodies against the 200-kDa outer, 160-kDa middle, and 68-kDa core subunits of the neurofilament triplet." | 1.29 | Antineurofilament and antiretinal antibodies in AIDS patients with cytomegalovirus retinitis. ( Cunningham-Rundles, S; Heinemann, MH; Klein, RF; Polsky, B; Rosberger, DF; Tshering, SL, 1994) |
| " Slit-lamp biomicroscopy revealed no toxic effects for any of the treated eyes." | 1.29 | Ocular toxicity of iontophoretic foscarnet in rabbits. ( Equi, RA; Lee, DA; Sarraf, DA; Verdon, W; Yoshizumi, MO, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schneider, EW | 1 |
| Elner, SG | 1 |
| van Kuijk, FJ | 1 |
| Goldberg, N | 1 |
| Lieberman, RM | 1 |
| Eliott, D | 1 |
| Johnson, MW | 1 |
| Okada, S | 1 |
| Kiyama, T | 1 |
| Sato, E | 1 |
| Tanaka, Y | 1 |
| Oizumi, T | 1 |
| Kuroishi, T | 1 |
| Takahashi, T | 1 |
| Sasaki, K | 1 |
| Sugawara, S | 1 |
| Endo, Y | 1 |
| Ridha, E | 1 |
| Cookson, H | 1 |
| Devitt, E | 1 |
| Nelson, M | 1 |
| Rapp, P | 1 |
| Pilon, F | 1 |
| Chiambaretta, F | 1 |
| Ménérath, JM | 1 |
| Jacomet, C | 1 |
| Chau Tran, TH | 1 |
| Cassoux, N | 1 |
| Bodaghi, B | 1 |
| Lehoang, P | 1 |
| Demols, P | 1 |
| Claes, CA | 1 |
| Farber, CM | 1 |
| Rasquin, F | 1 |
| Nakamoto, BK | 1 |
| Dorotheo, EU | 1 |
| Biousse, V | 1 |
| Tang, RA | 1 |
| Schiffman, JS | 1 |
| Newman, NJ | 1 |
| Rosberger, DF | 1 |
| Tshering, SL | 1 |
| Polsky, B | 1 |
| Heinemann, MH | 1 |
| Klein, RF | 1 |
| Cunningham-Rundles, S | 1 |
| Yoshizumi, MO | 1 |
| Lee, DA | 1 |
| Sarraf, DA | 1 |
| Equi, RA | 1 |
| Verdon, W | 1 |
| Sanz Moreno, J | 1 |
| López-Rubio, M | 1 |
| Calero-García, MA | 1 |
| Ratia-Jiménez, T | 1 |
| Arranz-Caso, A | 1 |
| Martínez-Martínez, J | 1 |
| Domingo Gordo, B | 1 |
| Luezas Morcuende, JJ | 1 |
| Vidal Fernández, P | 1 |
| Aparicio Hernández-Lastras, MJ | 1 |
| Suárez Leoz, M | 1 |
| Ulbricht, A | 1 |
| Färber, I | 1 |
| Wutzler, P | 1 |
1 review available for foscarnet and Necrosis
| Article | Year |
|---|---|
Progressive outer retinal necrosis presenting with isolated optic neuropathy.
Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infection | 2004 |
11 other studies available for foscarnet and Necrosis
| Article | Year |
|---|---|
Chronic retinal necrosis: cytomegalovirus necrotizing retinitis associated with panretinal vasculopathy in non-HIV patients.
Topics: Aged; Aged, 80 and over; Antiviral Agents; Aqueous Humor; CD4 Lymphocyte Count; Chronic Disease; Cyt | 2013 |
Inhibition of phosphate transporters ameliorates the inflammatory and necrotic side effects of the nitrogen-containing bisphosphonate zoledronate in mice.
Topics: Animals; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Foscarnet; Imidazo | 2013 |
Febrile neutropenia in a HIV positive individual post-chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cyclophosphamide; Cytomegalovirus | 2010 |
[Bilateral uveitis with definitive hypotony caused by systemic cidofovir].
Topics: AIDS-Related Opportunistic Infections; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; | 2003 |
Successful treatment with combination of systemic antiviral drugs and intravitreal ganciclovir injections in the management of severe necrotizing herpetic retinitis.
Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Foscarnet; Gancic | 2003 |
Macular CMV retinitis: a case report.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Fatal Out | 2004 |
Antineurofilament and antiretinal antibodies in AIDS patients with cytomegalovirus retinitis.
Topics: Acquired Immunodeficiency Syndrome; Antibodies; Antiviral Agents; Cytomegalovirus Retinitis; Foscarn | 1994 |
Ocular toxicity of iontophoretic foscarnet in rabbits.
Topics: Animals; Antiviral Agents; Choroid; Electroretinography; Foscarnet; Iontophoresis; Microscopy, Elect | 1995 |
Acute abdomen and intestinal necrosis produced by varicella-zoster virus in an immunocompromised host.
Topics: Abdomen, Acute; Aged; Antiviral Agents; Chickenpox; Fatal Outcome; Female; Foscarnet; Herpesvirus 3, | 1996 |
[Bilateral acute retinal necrosis due to herpes simplex virus in inmunocompetent people and acyclovir resistance].
Topics: Acute Disease; Acyclovir; Adult; Antiviral Agents; Diagnosis, Differential; Drug Therapy, Combinatio | 2002 |
Herpes simplex virus hepatitis in mice: effects of treatment with trisodium phosphonoformate.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Foscarnet; Hepatitis, Viral, Animal; Herpes Simpl | 1985 |