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foscarnet and Myelodysplastic Syndromes

foscarnet has been researched along with Myelodysplastic Syndromes in 4 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Myelodysplastic Syndromes: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.

Research Excerpts

ExcerptRelevanceReference
" Herpes simplex virus (HSV) reactivations are usually prevented by acyclovir (ACV) prophylaxis, whereas cidofovir (CDV) has been used off indication to manage AdV infections."7.83Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation. ( Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S, 2016)
" Herpes simplex virus (HSV) reactivations are usually prevented by acyclovir (ACV) prophylaxis, whereas cidofovir (CDV) has been used off indication to manage AdV infections."3.83Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation. ( Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S, 2016)
" Although prompt treatment with foscarnet stabilized encephalitis and there were no serious neurological sequelae, the patient developed both hyponatremia and natriuresis 11 days after intravenous administration of foscarnet."3.74[Salt-wasting nephropathy induced by foscarnet treatment for HHV-6 encephalitis in a hematopoietic stem cell transplant]. ( Akiyama, H; Ando, M; Koshida, A; Najima, Y; Ohashi, K; Sakamaki, H; Yamashita, T, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gutierrez, C1
Kebriaei, P1
Turner, KA1
Yemelyanova, A1
Ariza-Heredia, EJ1
Foo, WC1
Voigt, S1
Hofmann, J1
Edelmann, A1
Sauerbrei, A1
Kühl, JS1
Najima, Y1
Ohashi, K1
Ando, M1
Koshida, A1
Yamashita, T1
Akiyama, H1
Sakamaki, H1
Kiehl, MG1
Basara, N1

Trials

1 trial available for foscarnet and Myelodysplastic Syndromes

ArticleYear
Cidofovir for cytomegalovirus-preemptive therapy in stem cell transplant recipients.
    Blood, 2001, Sep-01, Volume: 98, Issue:5

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance,

2001

Other Studies

3 other studies available for foscarnet and Myelodysplastic Syndromes

ArticleYear
A unique presentation of acute liver failure from herpes simplex virus hepatitis.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:4

    Topics: Acyclovir; Adrenal Cortex Hormones; Antiviral Agents; Bone Marrow Transplantation; Drug Resistance,

2016
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5

    Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Chi

2016
[Salt-wasting nephropathy induced by foscarnet treatment for HHV-6 encephalitis in a hematopoietic stem cell transplant].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:1

    Topics: Antiviral Agents; Encephalitis, Viral; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; H

2008