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foscarnet and Leukodystrophy, Metachromatic

foscarnet has been researched along with Leukodystrophy, Metachromatic in 1 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Leukodystrophy, Metachromatic: An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.

Research Excerpts

ExcerptRelevanceReference
"Foscarnet was discontinued because of concern about its potential central nervous system toxicity."5.31Ganciclovir-resistant cytomegalovirus encephalitis in a bone marrow transplant recipient. ( Balfour, HH; Clark, HB; Holman, CJ; Julin, JE; Krivit, W; van Burik, JH; Webb, C, 2002)
"Foscarnet was discontinued because of concern about its potential central nervous system toxicity."1.31Ganciclovir-resistant cytomegalovirus encephalitis in a bone marrow transplant recipient. ( Balfour, HH; Clark, HB; Holman, CJ; Julin, JE; Krivit, W; van Burik, JH; Webb, C, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Julin, JE1
van Burik, JH1
Krivit, W1
Webb, C1
Holman, CJ1
Clark, HB1
Balfour, HH1

Other Studies

1 other study available for foscarnet and Leukodystrophy, Metachromatic

ArticleYear
Ganciclovir-resistant cytomegalovirus encephalitis in a bone marrow transplant recipient.
    Transplant infectious disease : an official journal of the Transplantation Society, 2002, Volume: 4, Issue:4

    Topics: Adult; Antiviral Agents; Bone Marrow Transplantation; Cytomegalovirus; Cytomegalovirus Infections; D

2002