foscarnet has been researched along with Graft vs Host Disease in 29 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Over an eight-month period from October 1997 to May 1998, four patients who had received bone marrow transplant (BMT) from unrelated donor presented with severe mucosal cutaneous infections involving acyclovir resistant herpes simplex virus 1 (HSV-1)." | 7.71 | Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation. ( Bordigoni, P; Carret, AS; Corsaro, D; Dauendorffer, JN; Edert, D; Le Faou, A; Venard, V, 2001) |
| "Three marrow transplant patients developed pneumonia due to acyclovir-resistant thymidine-kinase-deficient herpes simplex virus (HSV) type 1." | 7.68 | Acyclovir-resistant herpes simplex virus causing pneumonia after marrow transplantation. ( Ellis, MN; Hackman, RC; Ljungman, P; Meyers, JD; Shepp, DH, 1990) |
| " We report successful BCV use in management of disseminated acyclovir- and cidofovir-resistant varicella zoster virus in an immunocompromised hematopoietic stem cell transplant patient with chronic graft-versus-host disease who was intolerant to foscarnet." | 3.83 | Brincidofovir treatment of acyclovir-resistant disseminated varicella zoster virus infection in an immunocompromised host. ( Hartline, CB; Larson, RA; Mommeja-Marin, H; Mullane, KM; Nuss, C; Prichard, MN; Ridgeway, J; Theusch, J, 2016) |
| "Over an eight-month period from October 1997 to May 1998, four patients who had received bone marrow transplant (BMT) from unrelated donor presented with severe mucosal cutaneous infections involving acyclovir resistant herpes simplex virus 1 (HSV-1)." | 3.71 | Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation. ( Bordigoni, P; Carret, AS; Corsaro, D; Dauendorffer, JN; Edert, D; Le Faou, A; Venard, V, 2001) |
| " The first developed three episodes of cytomegaloviremia requiring anti-viral therapy; the third episode accompanied by cytomegalovirus hepatitis which required prolonged therapy with foscarnet." | 3.69 | Unusual infections following allogeneic bone marrow transplantation for chronic lymphocytic leukemia. ( Brincat, S; Catovsky, D; Iveson, T; Jameson, B; Mehta, J; Paul, B; Powles, R; Singhal, S; Treleaven, J; Zomas, A, 1994) |
| " Cytomegalovirus prophylaxis consisted of acyclovir for SIBs and foscarnet for MUDs." | 3.69 | Bone marrow transplantation for chronic myeloid leukemia (CML) from unrelated and sibling donors: single center experience. ( Bacigalupo, A; Barbanti, M; Corvo, R; Delfino, L; Ferrara, GB; Ficai, G; Frassoni, F; Ghinatti, C; Gualandi, F; Lamparelli, T; Morabito, A; Occhini, D; Pozzi, S; Sacchi, N; Van Lint, MT; Vitale, V; Zikos, P, 1997) |
| "Three marrow transplant patients developed pneumonia due to acyclovir-resistant thymidine-kinase-deficient herpes simplex virus (HSV) type 1." | 3.68 | Acyclovir-resistant herpes simplex virus causing pneumonia after marrow transplantation. ( Ellis, MN; Hackman, RC; Ljungman, P; Meyers, JD; Shepp, DH, 1990) |
| "We report a 34-year-old woman with acute lymphoblastic leukemia underwent allogenic bone marrow transplant (BMT)." | 1.31 | Giant cell lichenoid dermatitis within herpes zoster scars in a bone marrow recipient. ( Bartolomé, B; Córdoba, S; Fernández-Herrera, J; Fraga, J; García-Díez, A, 2000) |
| " Continued induction dosing or re-induction may protect against early breakthrough CMV disease and CMV-related death among patients with rising antigenemia on preemptive therapy." | 1.31 | Rising pp65 antigenemia during preemptive anticytomegalovirus therapy after allogeneic hematopoietic stem cell transplantation: risk factors, correlation with DNA load, and outcomes. ( Boeckh, M; Corey, L; Davis, C; Drew, WL; Gooley, T; Huang, M; Miner, R; Nichols, WG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 16 (55.17) | 29.6817 |
| 2010's | 7 (24.14) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Kuwatsuka, Y | 1 |
| Atsuta, Y | 1 |
| Hirakawa, A | 1 |
| Uchida, N | 1 |
| Inamoto, Y | 1 |
| Najima, Y | 1 |
| Ikegame, K | 1 |
| Eto, T | 2 |
| Ozawa, Y | 1 |
| Ichinohe, T | 1 |
| Inoue, M | 1 |
| Kimura, T | 1 |
| Okamoto, S | 1 |
| Miyamura, K | 1 |
| Fukuda, T | 2 |
| El Jurdi, N | 1 |
| Rogosheske, J | 1 |
| DeFor, T | 1 |
| Bejanyan, N | 1 |
| Arora, M | 1 |
| Bachanova, V | 1 |
| Betts, B | 1 |
| He, F | 1 |
| Holtan, S | 1 |
| Janakiram, M | 1 |
| Larson, S | 1 |
| Maakaron, J | 1 |
| Rashidi, A | 1 |
| Warlick, E | 1 |
| Wagner, JE | 1 |
| Young, JH | 1 |
| Weisdorf, D | 1 |
| Brunstein, CG | 1 |
| Ogata, M | 1 |
| Takano, K | 1 |
| Moriuchi, Y | 1 |
| Kondo, T | 1 |
| Ueki, T | 1 |
| Nakano, N | 1 |
| Mori, T | 1 |
| Uoshima, N | 1 |
| Nagafuji, K | 1 |
| Yamasaki, S | 1 |
| Shibasaki, Y | 1 |
| Sakai, R | 1 |
| Kato, K | 1 |
| Choi, I | 1 |
| Jo, Y | 1 |
| Kako, S | 1 |
| Oshima, K | 1 |
| Baghban, A | 1 |
| Malinis, M | 1 |
| Didsbury, MS | 1 |
| Mackie, FE | 1 |
| Kennedy, SE | 1 |
| Gutierrez, C | 1 |
| Kebriaei, P | 1 |
| Turner, KA | 1 |
| Yemelyanova, A | 1 |
| Ariza-Heredia, EJ | 1 |
| Foo, WC | 1 |
| Mullane, KM | 1 |
| Nuss, C | 1 |
| Ridgeway, J | 1 |
| Prichard, MN | 1 |
| Hartline, CB | 1 |
| Theusch, J | 1 |
| Mommeja-Marin, H | 1 |
| Larson, RA | 1 |
| Shimizu, R | 1 |
| Ohwada, C | 1 |
| Nagao, Y | 1 |
| Togasaki, E | 1 |
| Kawajiri, C | 1 |
| Muto, T | 1 |
| Tsukamoto, S | 1 |
| Sakai, S | 1 |
| Takeda, Y | 1 |
| Mimura, N | 1 |
| Takeuchi, M | 1 |
| Sakaida, E | 1 |
| Iseki, T | 1 |
| Nakaseko, C | 1 |
| Travi, G | 1 |
| Pergam, SA | 1 |
| Xie, H | 1 |
| Boeckh, MJ | 1 |
| Guo, Z | 1 |
| Chen, HR | 1 |
| Liu, XD | 1 |
| Bian, JM | 1 |
| He, XP | 1 |
| Lou, JX | 1 |
| Chen, P | 1 |
| Yang, K | 1 |
| Liu, D | 1 |
| Zhang, Y | 1 |
| Aoyama, Y | 1 |
| Yamamura, R | 1 |
| Shima, E | 1 |
| Nakamae, H | 1 |
| Makita, K | 1 |
| Hasegawa, T | 1 |
| Sakamoto, C | 1 |
| Terada, Y | 1 |
| Kho, G | 1 |
| Ohta, K | 1 |
| Yamane, T | 1 |
| Takubo, T | 1 |
| Hino, M | 1 |
| Boeckh, M | 3 |
| Nichols, WG | 2 |
| Papanicolaou, G | 1 |
| Rubin, R | 1 |
| Wingard, JR | 1 |
| Zaia, J | 1 |
| Avery, RK | 1 |
| Bolwell, BJ | 1 |
| Yen-Lieberman, B | 1 |
| Lurain, N | 1 |
| Waldman, WJ | 1 |
| Longworth, DL | 1 |
| Taege, AJ | 1 |
| Mossad, SB | 1 |
| Kohn, D | 1 |
| Long, JR | 1 |
| Curtis, J | 1 |
| Kalaycio, M | 1 |
| Pohlman, B | 1 |
| Williams, JW | 1 |
| Shereck, EB | 1 |
| Cooney, E | 1 |
| van de Ven, C | 1 |
| Della-Lotta, P | 1 |
| Cairo, MS | 1 |
| Matsumura, T | 1 |
| Narimatsu, H | 1 |
| Kami, M | 1 |
| Yuji, K | 1 |
| Kusumi, E | 1 |
| Hori, A | 1 |
| Murashige, N | 1 |
| Tanaka, Y | 1 |
| Masuoka, K | 1 |
| Wake, A | 1 |
| Miyakoshi, S | 1 |
| Kanda, Y | 1 |
| Taniguchi, S | 1 |
| Pöhlmann, C | 1 |
| Schetelig, J | 1 |
| Reuner, U | 1 |
| Bornhäuser, M | 1 |
| Illmer, T | 1 |
| Kiani, A | 1 |
| Ehninger, G | 1 |
| Jacobs, E | 1 |
| Rohayem, J | 1 |
| Chamberlain, MC | 1 |
| Chowdhary, S | 1 |
| Zomas, A | 1 |
| Mehta, J | 1 |
| Powles, R | 1 |
| Treleaven, J | 1 |
| Iveson, T | 1 |
| Singhal, S | 1 |
| Jameson, B | 1 |
| Paul, B | 1 |
| Brincat, S | 1 |
| Catovsky, D | 1 |
| Lamparelli, T | 1 |
| Van Lint, MT | 1 |
| Gualandi, F | 1 |
| Occhini, D | 1 |
| Barbanti, M | 1 |
| Sacchi, N | 1 |
| Ficai, G | 1 |
| Ghinatti, C | 1 |
| Ferrara, GB | 1 |
| Delfino, L | 1 |
| Pozzi, S | 1 |
| Morabito, A | 1 |
| Zikos, P | 1 |
| Vitale, V | 1 |
| Corvo, R | 1 |
| Frassoni, F | 1 |
| Bacigalupo, A | 1 |
| Ljungman, P | 2 |
| Aschan, J | 1 |
| Lewensohn-Fuchs, I | 1 |
| Carlens, S | 1 |
| Larsson, K | 1 |
| Lönnqvist, B | 1 |
| Mattsson, J | 1 |
| Sparrelid, E | 1 |
| Winiarski, J | 1 |
| Ringdén, O | 1 |
| Tiacci, E | 1 |
| Luppi, M | 1 |
| Barozzi, P | 1 |
| Gurdo, G | 1 |
| Tabilio, A | 1 |
| Ballanti, S | 1 |
| Torelli, G | 1 |
| Aversa, F | 1 |
| Córdoba, S | 1 |
| Fraga, J | 1 |
| Bartolomé, B | 1 |
| García-Díez, A | 1 |
| Fernández-Herrera, J | 1 |
| Corey, L | 2 |
| Gooley, T | 1 |
| Drew, WL | 1 |
| Miner, R | 1 |
| Huang, M | 1 |
| Davis, C | 1 |
| Crippa, F | 1 |
| Chuang, EL | 1 |
| Sale, G | 1 |
| Venard, V | 1 |
| Dauendorffer, JN | 1 |
| Carret, AS | 1 |
| Corsaro, D | 1 |
| Edert, D | 1 |
| Bordigoni, P | 1 |
| Le Faou, A | 1 |
| Hambach, L | 1 |
| Eder, M | 1 |
| Dammann, E | 1 |
| Battmer, K | 1 |
| Stucki, A | 1 |
| Heil, G | 1 |
| Ganser, A | 1 |
| Hertenstein, B | 1 |
| Arnulf, B | 1 |
| Chebbi, F | 1 |
| Lefrere, F | 1 |
| Ait Arkoub, Z | 1 |
| Varet, B | 1 |
| Fillet, AM | 1 |
| Chakrabarti, S | 1 |
| Collingham, KE | 1 |
| Osman, H | 1 |
| Fegan, CD | 1 |
| Milligan, DW | 1 |
| Ellis, MN | 1 |
| Hackman, RC | 1 |
| Shepp, DH | 1 |
| Meyers, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II, Multicentric, Prospective and Opened Clinical Trial of Advance Valganciclovir Treatment of CMV in Allogenic Hematopoietic Progenitors Transplant[NCT00386412] | Phase 2 | 132 participants (Anticipated) | Interventional | 2005-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for foscarnet and Graft vs Host Disease
| Article | Year |
|---|---|
Ganciclovir and foscarnet dual-therapy for cytomegalovirus encephalitis: A case report and review of the literature.
Topics: Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, Combination; Encephalitis, Viral; Female | 2018 |
A systematic review of acute kidney injury in pediatric allogeneic hematopoietic stem cell recipients.
Topics: Acute Kidney Injury; Adolescent; Amphotericin B; Biomarkers; Child; Cyclosporine; Foscarnet; Glomeru | 2015 |
Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies.
Topics: Acyclovir; Antigens, CD34; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscar | 2003 |
Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bone Marrow Transplantation | 2001 |
2 trials available for foscarnet and Graft vs Host Disease
| Article | Year |
|---|---|
Effects of Prophylactic Foscarnet on Human Herpesvirus-6 Reactivation and Encephalitis in Cord Blood Transplant Recipients: A Prospective Multicenter Trial with an Historical Control Group.
Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Encephalitis, Viral; Female; Fetal Blood; Fos | 2018 |
A pilot phase II study of alternate day ganciclovir and foscarnet in preventing cytomegalovirus (CMV) infections in at-risk pediatric and adolescent allogeneic stem cell transplant recipients.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cytomegalovirus Infections; Drug Admin | 2007 |
23 other studies available for foscarnet and Graft vs Host Disease
| Article | Year |
|---|---|
Use of unapproved or off-label drugs in Japan for the treatment of graft-versus-host disease and post-transplant viral infection.
Topics: Acute Disease; Adult; Beclomethasone; Chronic Disease; Cidofovir; Cytomegalovirus Infections; Etaner | 2020 |
Prophylactic Foscarnet for Human Herpesvirus 6: Effect on Hematopoietic Engraftment after Reduced-Intensity Conditioning Umbilical Cord Blood Transplantation.
Topics: Cord Blood Stem Cell Transplantation; Foscarnet; Graft vs Host Disease; Hematopoietic Stem Cell Tran | 2021 |
A unique presentation of acute liver failure from herpes simplex virus hepatitis.
Topics: Acyclovir; Adrenal Cortex Hormones; Antiviral Agents; Bone Marrow Transplantation; Drug Resistance, | 2016 |
Brincidofovir treatment of acyclovir-resistant disseminated varicella zoster virus infection in an immunocompromised host.
Topics: Acyclovir; Adult; Antibiotic Prophylaxis; Antineoplastic Agents; Antiviral Agents; Cytosine; Drug Re | 2016 |
The Successful Treatment of a Cord Blood Transplant Recipient with Varicella Zoster Virus Meningitis, Radiculitis and Myelitis with Foscarnet.
Topics: Acyclovir; Antiviral Agents; Foscarnet; Graft vs Host Disease; Hematopoietic Stem Cell Transplantati | 2017 |
Donor CMV serostatus not predictive of relapse in D-/R- pediatric HCT.
Topics: Acyclovir; Adolescent; Adult; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Child; Child, Pr | 2009 |
[Clinical analysis of cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation].
Topics: Adolescent; Adult; Child; Child, Preschool; Cytomegalovirus Infections; Female; Foscarnet; Ganciclov | 2012 |
[Successful treatment with foscarnet for disseminated varicella-zoster infection after reduced intensity stem cell transplantation in a case of relapsed refractory central nervous system lymphoma].
Topics: Acyclovir; Adult; Antiviral Agents; Central Nervous System Neoplasms; Drug Resistance, Viral; Foscar | 2003 |
Use of leflunomide in an allogeneic bone marrow transplant recipient with refractory cytomegalovirus infection.
Topics: Bone Marrow Transplantation; Cytomegalovirus Infections; Drug Resistance, Viral; Drug Therapy, Combi | 2004 |
Cytomegalovirus infections following umbilical cord blood transplantation using reduced intensity conditioning regimens for adult patients.
Topics: Adolescent; Adult; Aged; Cord Blood Stem Cell Transplantation; Cytomegalovirus; Cytomegalovirus Infe | 2007 |
Cidofovir and foscarnet for treatment of human herpesvirus 6 encephalitis in a neutropenic stem cell transplant recipient.
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Encephalitis, Viral; Foscarnet; Gr | 2007 |
Post-transplant acute limbic encephalitis: clinical features and relationship to HHV6.
Topics: Antiviral Agents; Brain; Confusion; Diagnosis, Differential; DNA, Viral; Female; Foscarnet; Ganciclo | 2008 |
Unusual infections following allogeneic bone marrow transplantation for chronic lymphocytic leukemia.
Topics: Adult; Anti-Bacterial Agents; Bone Marrow Transplantation; Cytomegalovirus Infections; Drug Therapy, | 1994 |
Bone marrow transplantation for chronic myeloid leukemia (CML) from unrelated and sibling donors: single center experience.
Topics: Acyclovir; Adolescent; Adult; Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Cause | 1997 |
Results of different strategies for reducing cytomegalovirus-associated mortality in allogeneic stem cell transplant recipients.
Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Transplantation; Child; Chi | 1998 |
Fatal herpesvirus-6 encephalitis in a recipient of a T-cell-depleted peripheral blood stem cell transplant from a 3-loci mismatched related donor.
Topics: Cytomegalovirus Infections; DNA, Viral; Encephalitis, Viral; Fatal Outcome; Foscarnet; Ganciclovir; | 2000 |
Giant cell lichenoid dermatitis within herpes zoster scars in a bone marrow recipient.
Topics: Acyclovir; Adult; Antiviral Agents; Bone Marrow Transplantation; Cicatrix; Dermatitis; Female; Fosca | 2000 |
Rising pp65 antigenemia during preemptive anticytomegalovirus therapy after allogeneic hematopoietic stem cell transplantation: risk factors, correlation with DNA load, and outcomes.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antigens, Viral; Antiviral Agents; Cause of Death; | 2001 |
Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation.
Topics: Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cyt | 2001 |
Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation.
Topics: Acute Disease; Acyclovir; Adolescent; Amino Acid Substitution; Antiviral Agents; Bone Marrow Transpl | 2001 |
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofov | 2001 |
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections.
Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytos | 2001 |
Acyclovir-resistant herpes simplex virus causing pneumonia after marrow transplantation.
Topics: Acyclovir; Adult; Animals; Antiviral Agents; Bone Marrow Transplantation; Cells, Cultured; Drug Resi | 1990 |