Page last updated: 2024-10-27

foscarnet and Genital Herpes

foscarnet has been researched along with Genital Herpes in 35 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Research Excerpts

ExcerptRelevanceReference
"A double blind, placebo controlled trial was performed in nine sexually transmitted diseases (STD) clinics in the United Kingdom and the Netherlands to investigate the efficacy of trisodium phosphonoformate (foscarnet) cream in treating recurrent genital herpes simplex virus (HSV) infection."9.06Topical treatment of recurrent genital herpes simplex virus infections with trisodium phosphonoformate (foscarnet): double blind, placebo controlled, multicentre study. ( Barton, SE; Essex-Cater, AJ; Kinghorn, GR; Kuijpers, MH; Munday, PE; Notowicz, A; Rashid, S; Schuller, JL; Stolz, E; van der Meijden, WI, 1986)
"Clinic-initiated topical treatment of recurrent genital herpes with foscarnet cream (concentration, 0."9.06Clinical course of recurrent genital herpes and treatment with foscarnet cream: results of a Canadian multicenter trial. ( Aoki, FY; Bright, C; Kaluski, J; Lawee, D; Poisson, M; Portnoy, J; Sacks, SL; Schlech, W; Tyrrell, DL, 1987)
"Sequential herpes simplex virus (HSV) isolates from AIDS patients receiving foscarnet therapy were evaluated for susceptibility to adefovir."7.71Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy. ( Bestman-Smith, J; Boivin, G, 2002)
"Sequential human-immunodeficiency virus type 1 (HIV-1) isolates from an acquired immunodeficiency syndrome (AIDS) patient on long-term foscarnet and zidovudine therapy were examined for the emergence of foscarnet resistance."7.69Long-term foscarnet therapy not associated with the development of foscarnet-resistant human immunodeficiency virus type 1 in an acquired immunodeficiency syndrome patient. ( Birch, C; Hoy, J; McGavin, K; Tachedjian, G, 1994)
" One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to acyclovir and was intolerant of foscarnet."7.69Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). ( Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G, 1994)
"The activity of phosphonoacetic acid (PAA) and phosphonoformic acid (PFA) against four strains of herpes simplex virus type 1 (HSV-1) and four strains of HSV-2 were compared in tissue culture and in a murine model of genital herpes."7.66A comparison of phosphonoacetic acid and phosphonoformic acid activity in genital herpes simplex virus type 1 and type 2 infections of mice. ( Glasgow, LA; Kern, ER; Overall, JC; Richards, JT, 1981)
"Although initial recurrences of herpes simplex infection after the index lesion had healed tended to be susceptible to acyclovir, acyclovir-resistant infection eventually recurred in every healed patient, a median of 42."6.67A controlled trial comparing foscarnet with vidarabine for acyclovir-resistant mucocutaneous herpes simplex in the acquired immunodeficiency syndrome. The AIDS Clinical Trials Group. ( Chatis, P; Crumpacker, C; Davis, R; Hafner, R; Kessler, HA; Landry, B; Mills, J; Rush, J; Safrin, S, 1991)
"Treatment with foscarnet cream was not associated with any significant side effects."6.66Foscarnet (phosphonoformate sodium) in the treatment of recurrent male genital herpes. ( Doraisingham, S; Lee, CT; Lim, KB; Ling, AE; Tan, T; Thirumoorthy, T, 1986)
"Foscarnet treated men with subpreputial lesions had a shorter period of ulcers (1."6.66Topical treatment of recurrent genital herpes infections with foscarnet. ( Lernestedt, JO; Lycke, E; Ogenstad, S; Wallin, J, 1985)
"Genital herpes is an important cofactor for acquisition of human immunodeficiency virus (HIV) infection, and effective prophylaxis is a helpful strategy to halt both HIV and herpes simplex virus (HSV) transmission."5.48The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase. ( Andrei, G; Gillemot, S; Snoeck, R; Topalis, D, 2018)
"A double blind, placebo controlled trial was performed in nine sexually transmitted diseases (STD) clinics in the United Kingdom and the Netherlands to investigate the efficacy of trisodium phosphonoformate (foscarnet) cream in treating recurrent genital herpes simplex virus (HSV) infection."5.06Topical treatment of recurrent genital herpes simplex virus infections with trisodium phosphonoformate (foscarnet): double blind, placebo controlled, multicentre study. ( Barton, SE; Essex-Cater, AJ; Kinghorn, GR; Kuijpers, MH; Munday, PE; Notowicz, A; Rashid, S; Schuller, JL; Stolz, E; van der Meijden, WI, 1986)
"Clinic-initiated topical treatment of recurrent genital herpes with foscarnet cream (concentration, 0."5.06Clinical course of recurrent genital herpes and treatment with foscarnet cream: results of a Canadian multicenter trial. ( Aoki, FY; Bright, C; Kaluski, J; Lawee, D; Poisson, M; Portnoy, J; Sacks, SL; Schlech, W; Tyrrell, DL, 1987)
"Recurrent anogenital herpes simplex virus infections are common in patients with human immunodeficiency virus (HIV), of whom approximately 5% develop resistance to acyclovir."3.85Surgical excision for recurrent herpes simplex virus 2 (HSV-2) anogenital infection in a patient with human immunodeficiency virus (HIV). ( Arinze, F; Raffanti, S; Shaver, A, 2017)
"Sequential herpes simplex virus (HSV) isolates from AIDS patients receiving foscarnet therapy were evaluated for susceptibility to adefovir."3.71Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy. ( Bestman-Smith, J; Boivin, G, 2002)
"Sequential human-immunodeficiency virus type 1 (HIV-1) isolates from an acquired immunodeficiency syndrome (AIDS) patient on long-term foscarnet and zidovudine therapy were examined for the emergence of foscarnet resistance."3.69Long-term foscarnet therapy not associated with the development of foscarnet-resistant human immunodeficiency virus type 1 in an acquired immunodeficiency syndrome patient. ( Birch, C; Hoy, J; McGavin, K; Tachedjian, G, 1994)
" One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to acyclovir and was intolerant of foscarnet."3.69Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). ( Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G, 1994)
"A rapid screening test for antiviral susceptibility to acyclovir and foscarnet was evaluated in 320 herpes simplex virus (HSV) isolates from 197 patients."3.69A rapid screen test for in vitro susceptibility of clinical herpes simplex virus isolates. ( Elbeik, T; Mills, J; Safrin, S, 1994)
"In an AIDS patient who had repeated successful treatment with acyclovir in his history, erosive herpes perianalis with herpes proctitis appeared, which persisted over several weeks."3.68[Chronic erosive, therapy-resistant perianal herpes (type II) with herpes proctitis in AIDS]. ( Bratzke, B; Ehlers, G; Orfanos, CE; Stavermann, T, 1991)
"The activity of phosphonoacetic acid (PAA) and phosphonoformic acid (PFA) against four strains of herpes simplex virus type 1 (HSV-1) and four strains of HSV-2 were compared in tissue culture and in a murine model of genital herpes."3.66A comparison of phosphonoacetic acid and phosphonoformic acid activity in genital herpes simplex virus type 1 and type 2 infections of mice. ( Glasgow, LA; Kern, ER; Overall, JC; Richards, JT, 1981)
"Although initial recurrences of herpes simplex infection after the index lesion had healed tended to be susceptible to acyclovir, acyclovir-resistant infection eventually recurred in every healed patient, a median of 42."2.67A controlled trial comparing foscarnet with vidarabine for acyclovir-resistant mucocutaneous herpes simplex in the acquired immunodeficiency syndrome. The AIDS Clinical Trials Group. ( Chatis, P; Crumpacker, C; Davis, R; Hafner, R; Kessler, HA; Landry, B; Mills, J; Rush, J; Safrin, S, 1991)
"Treatment with foscarnet cream was not associated with any significant side effects."2.66Foscarnet (phosphonoformate sodium) in the treatment of recurrent male genital herpes. ( Doraisingham, S; Lee, CT; Lim, KB; Ling, AE; Tan, T; Thirumoorthy, T, 1986)
"Foscarnet treated men with subpreputial lesions had a shorter period of ulcers (1."2.66Topical treatment of recurrent genital herpes infections with foscarnet. ( Lernestedt, JO; Lycke, E; Ogenstad, S; Wallin, J, 1985)
"The mechanism of recurrence is yet not fully elucidated and therapy still remains a problem."2.36[Herpes simplex]. ( Fanta, D, 1981)
"Genital herpes is an important cofactor for acquisition of human immunodeficiency virus (HIV) infection, and effective prophylaxis is a helpful strategy to halt both HIV and herpes simplex virus (HSV) transmission."1.48The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase. ( Andrei, G; Gillemot, S; Snoeck, R; Topalis, D, 2018)
"The foscarnet resistance was associated with an S725G mutation in a conserved region (region II) of the herpesvirus DNA pol gene."1.31Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient. ( Birch, C; Chibo, D; Doherty, R; Mijch, A, 2002)
" In a comparative study with this 3-day dosage schedule, the efficacy of daily doses of 50 mg of FMAU per kg was greater than that of the same doses of FIAC and FIAU, in that order; all these were more effective than daily doses of 50, 100, or 200 mg of acyclovir or of 500 mg of phosphonoformic acid per kg."1.27Treatment of primary acute genital herpes in guinea pigs by intraperitoneal administration of fluoropyrimidines. ( Hsiung, GD; Mayo, DR, 1984)
"Using a guinea pig model of genital herpes simplex virus (HSV) type 2 infection, phosphonoformate treatment initiated after the onset of symptoms had a therapeutic effect on the outcome of disease."1.27Effect of phosphonoformate on symptomatic genital herpes simplex virus type 2 infection of guinea pigs. ( Hsiung, GD; Lucia, HL; Mayo, DR, 1983)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199010 (28.57)18.7374
1990's14 (40.00)18.2507
2000's9 (25.71)29.6817
2010's2 (5.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arinze, F1
Shaver, A1
Raffanti, S1
Andrei, G2
Gillemot, S1
Topalis, D1
Snoeck, R2
Yudin, MH1
Kaul, R1
Brown, TJ1
McCrary, M1
Tyring, SK1
Chibo, D1
Mijch, A1
Doherty, R1
Birch, C2
Brummitt, CF1
Ghislanzoni, M1
Cusini, M1
Zerboni, R1
Alessi, E1
Mayo, DR2
Hsiung, GD2
Kern, ER1
Richards, JT1
Overall, JC1
Glasgow, LA1
Fanta, D1
Lucia, HL1
Li, YY1
Minagawa, H1
Tanaka, S1
Mori, R1
Tachedjian, G1
Hoy, J1
McGavin, K1
Gérard, M1
Silverman, A1
Hedderman, A1
Balzarini, J1
Sadzot-Delvaux, C1
Tricot, G1
Clumeck, N1
De Clercq, E1
Safrin, S3
Elbeik, T1
Mills, J2
Kemmerly, S1
Plotkin, B1
Smith, T1
Weissbach, N1
De Veranez, D1
Phan, LD1
Cohn, D1
Baumann, R1
Wunderli, W2
Riess, C1
Vogt, M1
Beasley, KL1
Cooley, GE1
Kao, GF1
Lowitt, MH1
Burnett, JW1
Aurelian, L1
Scoular, A1
Barton, S1
Pechère, M1
Trellu-Toutous, L1
Harms, M1
Saura, JH1
Krischer, J1
Alvarez-McLeod, A1
Havlik, J1
Drew, KE1
Bernstein, DI1
Ireland, J1
Bourne, N1
Arnulf, B1
Chebbi, F1
Lefrere, F1
Ait Arkoub, Z1
Varet, B1
Fillet, AM1
Aoki, FY2
Bestman-Smith, J1
Boivin, G1
Crumpacker, C1
Chatis, P1
Davis, R1
Hafner, R1
Rush, J1
Kessler, HA1
Landry, B1
Bratzke, B1
Orfanos, CE1
Stavermann, T1
Ehlers, G1
Spitzbart, H1
Seyffert, C1
Thust, U1
Chatis, PA1
Miller, CH1
Schrager, LE1
Crumpacker, CS1
Youle, MM1
Hawkins, DA1
Collins, P1
Shanson, DC1
Evans, R1
Oliver, N1
Lawrence, A1
Barton, SE1
Munday, PE1
Kinghorn, GR1
van der Meijden, WI1
Stolz, E1
Notowicz, A1
Rashid, S1
Schuller, JL1
Essex-Cater, AJ1
Kuijpers, MH1
Sacks, SL1
Portnoy, J1
Lawee, D1
Schlech, W1
Tyrrell, DL1
Poisson, M1
Bright, C1
Kaluski, J1
Lim, KB1
Doraisingham, S1
Thirumoorthy, T1
Lee, CT1
Ling, AE1
Tan, T1
Wallin, J1
Lernestedt, JO1
Ogenstad, S1
Lycke, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Infection in Patients With the Acquired Immunodeficiency Syndrome: A Randomized Multicenter Study of Foscarnet Versus Vidarabine[NCT00000985]Phase 326 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for foscarnet and Genital Herpes

ArticleYear
Antiviral agents: Non-antiretroviral [correction of Nonantiviral] drugs.
    Journal of the American Academy of Dermatology, 2002, Volume: 47, Issue:4

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Chickenpox; Cytomegalovirus Infections; Famciclovir; Fos

2002
[Herpes simplex].
    Wiener klinische Wochenschrift, 1981, Dec-25, Volume: 93, Issue:24

    Topics: Adolescent; Adult; Amantadine; Antigens, Viral; Cell Transformation, Viral; Female; Foscarnet; Herpe

1981
Management of genital herpes in HIV-infected patients.
    Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:2

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral A

2001

Trials

5 trials available for foscarnet and Genital Herpes

ArticleYear
A controlled trial comparing foscarnet with vidarabine for acyclovir-resistant mucocutaneous herpes simplex in the acquired immunodeficiency syndrome. The AIDS Clinical Trials Group.
    The New England journal of medicine, 1991, Aug-22, Volume: 325, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Drug Resistance, Microbial;

1991
Topical treatment of recurrent genital herpes simplex virus infections with trisodium phosphonoformate (foscarnet): double blind, placebo controlled, multicentre study.
    Genitourinary medicine, 1986, Volume: 62, Issue:4

    Topics: Administration, Topical; Clinical Trials as Topic; Double-Blind Method; Female; Foscarnet; Herpes Ge

1986
Clinical course of recurrent genital herpes and treatment with foscarnet cream: results of a Canadian multicenter trial.
    The Journal of infectious diseases, 1987, Volume: 155, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Antiviral Agents; Clinical Trials as Topic; Double-Blind

1987
Foscarnet (phosphonoformate sodium) in the treatment of recurrent male genital herpes.
    Annals of the Academy of Medicine, Singapore, 1986, Volume: 15, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antiviral Agents; Clinical Trials as Topic; Double

1986
Topical treatment of recurrent genital herpes infections with foscarnet.
    Scandinavian journal of infectious diseases, 1985, Volume: 17, Issue:2

    Topics: Administration, Topical; Adult; Clinical Trials as Topic; Double-Blind Method; Erythema; Female; Fos

1985

Other Studies

27 other studies available for foscarnet and Genital Herpes

ArticleYear
Surgical excision for recurrent herpes simplex virus 2 (HSV-2) anogenital infection in a patient with human immunodeficiency virus (HIV).
    Infection, 2017, Volume: 45, Issue:5

    Topics: Acyclovir; Antiviral Agents; Drug Resistance, Viral; Foscarnet; Herpes Genitalis; Herpesvirus 2, Hum

2017
The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase.
    The Journal of infectious diseases, 2018, 02-14, Volume: 217, Issue:5

    Topics: Acyclovir; Amino Acid Substitution; Antiviral Agents; Cells, Cultured; DNA Mutational Analysis; DNA-

2018
Progressive hypertrophic genital herpes in an HIV-infected woman despite immune recovery on antiretroviral therapy.
    Infectious diseases in obstetrics and gynecology, 2008, Volume: 2008

    Topics: Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Aminoquinolines; Antineoplast

2008
Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2002, Volume: 25, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; DNA-Directed DNA Polymera

2002
Imiquimod 5% cream for the treatment of recurrent, acyclovir-resistant genital herpes.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Feb-15, Volume: 42, Issue:4

    Topics: Acyclovir; Administration, Topical; Aged; Aminoquinolines; Antiviral Agents; Arthritis, Rheumatoid;

2006
Chronic hypertrophic acyclovir-resistant genital herpes treated with topical cidofovir and with topical foscarnet at recurrence in an HIV-positive man.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20, Issue:7

    Topics: Acyclovir; Administration, Topical; Antiretroviral Therapy, Highly Active; Antiviral Agents; Chronic

2006
Treatment of primary acute genital herpes in guinea pigs by intraperitoneal administration of fluoropyrimidines.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cytarabine; Female; Foscarnet; Guinea

1984
A comparison of phosphonoacetic acid and phosphonoformic acid activity in genital herpes simplex virus type 1 and type 2 infections of mice.
    Antiviral research, 1981, Volume: 1, Issue:4

    Topics: Animals; Antiviral Agents; Drug Evaluation, Preclinical; Female; Foscarnet; Ganglia, Spinal; Herpes

1981
Effect of phosphonoformate on symptomatic genital herpes simplex virus type 2 infection of guinea pigs.
    Intervirology, 1983, Volume: 19, Issue:1

    Topics: Animals; Antiviral Agents; Drug Evaluation, Preclinical; Female; Foscarnet; Ganglia, Spinal; Guinea

1983
Suppression of infectious virus spread to the liver by foscarnet following lethal infection of acyclovir-resistant herpes simplex virus type 2 in mice.
    Antiviral research, 1995, Volume: 27, Issue:1-2

    Topics: Acyclovir; Animals; Arabinonucleosides; Brain; Chlorocebus aethiops; Drug Resistance, Microbial; Fos

1995
Long-term foscarnet therapy not associated with the development of foscarnet-resistant human immunodeficiency virus type 1 in an acquired immunodeficiency syndrome patient.
    Journal of medical virology, 1994, Volume: 42, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Fo

1994
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4

    Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1994
A rapid screen test for in vitro susceptibility of clinical herpes simplex virus isolates.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:4

    Topics: Acyclovir; Animals; Drug Resistance, Microbial; Evaluation Studies as Topic; Foscarnet; Herpes Genit

1994
Foscarnet-resistant herpes simplex virus infection in patients with AIDS.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Drug Resistance, Microbial; Drug Therapy, C

1994
[Acyclovir-resistant Herpes simplex viruses in HIV-infected patients].
    Schweizerische medizinische Wochenschrift, 1993, Dec-28, Volume: 123, Issue:51-52

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Drug Resistance, Microbial; Female; Foscarn

1993
Herpes simplex vegetans: atypical genital herpes infection in a patient with common variable immunodeficiency.
    Journal of the American Academy of Dermatology, 1997, Volume: 37, Issue:5 Pt 2

    Topics: Acyclovir; Adult; Biopsy; Common Variable Immunodeficiency; Drug Resistance, Microbial; Female; Feta

1997
Therapy for genital herpes in immunocompromised patients: a national survey. The Herpes Simplex Advisory Panel.
    Genitourinary medicine, 1997, Volume: 73, Issue:5

    Topics: 2-Aminopurine; Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Drug Resistance,

1997
Treatment of acyclovir-resistant herpetic ulceration with topical foscarnet and antiviral sensitivity analysis.
    Dermatology (Basel, Switzerland), 1998, Volume: 197, Issue:3

    Topics: Acyclovir; Administration, Topical; Antiviral Agents; Drug Resistance, Microbial; Female; Foscarnet;

1998
Foscarnet treatment of genital infection due to acyclovir-resistant herpes simplex virus type 2 in a pregnant patient with AIDS: case report.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 29, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Drug Resistance; Female; Fos

1999
Pathogenesis of acyclovir-resistant herpes simplex type 2 isolates in animal models of genital herpes: models for antiviral evaluations.
    Antiviral research, 2000, Volume: 47, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Disease Models, Animal; Drug Resistance,

2000
Herpes study and resources.
    Treatment review, 1997, Issue:No 25

    Topics: 2-Aminopurine; Acyclovir; Adult; Antiviral Agents; Biopolymers; Catechin; Clinical Trials as Topic;

1997
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
    Bone marrow transplantation, 2001, Volume: 28, Issue:8

    Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofov

2001
Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy.
    Journal of medical virology, 2002, Volume: 67, Issue:1

    Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Foscarnet; Herpes Genitalis; Herpes

2002
[Chronic erosive, therapy-resistant perianal herpes (type II) with herpes proctitis in AIDS].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1991, Volume: 42, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Dose-Response Relationship,

1991
[Triapten ointment in the treatment of herpes genitalis in the female].
    Zentralblatt fur Gynakologie, 1990, Volume: 112, Issue:17

    Topics: Antiviral Agents; Female; Foscarnet; Herpes Genitalis; Humans; Ointments; Phosphonoacetic Acid; Uter

1990
Successful treatment with foscarnet of an acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with acquired immunodeficiency syndrome.
    The New England journal of medicine, 1989, Feb-02, Volume: 320, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Drug Resistance, Microbial;

1989
Acyclovir-resistant herpes in AIDS treated with foscarnet.
    Lancet (London, England), 1988, Aug-06, Volume: 2, Issue:8606

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Drug Resistance, Microbial; Female; Foscarnet;

1988