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foscarnet and Eye Infections, Viral

foscarnet has been researched along with Eye Infections, Viral in 59 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Eye Infections, Viral: Infections of the eye caused by minute intracellular agents. These infections may lead to severe inflammation in various parts of the eye - conjunctiva, iris, eyelids, etc. Several viruses have been identified as the causative agents. Among these are Herpesvirus, Adenovirus, Poxvirus, and Myxovirus.

Research Excerpts

ExcerptRelevanceReference
"In a controlled trial of foscarnet in the treatment of cytomegalovirus (CMV) retinitis in patients with the acquired immunodeficiency syndrome (AIDS), patients with non-immediately sight-threatening lesions were randomized to receive immediate treatment with foscarnet or foscarnet treatment delayed until the first signs of retinitis progression."9.07Design of a randomized controlled trial of foscarnet in patients with cytomegalovirus retinitis associated with acquired immunodeficiency syndrome. ( Polis, MA, 1992)
"To evaluate foscarnet sodium in treating cytomegalovirus retinitis in patients with AIDS."9.07A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS. ( Baird, BF; Davey, RT; Davis, M; De Smet, MD; Falloon, J; Kovacs, JA; Palestine, AG; Polis, MA; Zunich, KM; Zurlo, JJ, 1991)
"The use of ganciclovir in the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS) is limited by marrow toxicity and by the development of resistance to this agent in CMV strains capable of causing progressive disease."8.78Maintenance therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: foscarnet. ( Jacobson, MA, 1992)
"To report use of intravenous foscarnet or cidofovir for the treatment of refractory acute retinal necrosis (ARN)."7.88Treatment of Refractory Acute Retinal Necrosis with Intravenous Foscarnet or Cidofovir. ( Barshak, MB; Durand, ML; Foster, CS; Kim, IK; Mali, JO; Scott, NL; Stryjewski, TP; Tobin, EH; Young, LH, 2018)
"To study the effects of intravitreal foscarnet and the clinical differences between varicella zoster virus (VZV) and herpes simplex virus (HSV) induced acute retinal necrosis (ARN)."7.76Acute retinal necrosis: the effects of intravitreal foscarnet and virus type on outcome. ( Graham, EM; Laidlaw, DA; Pavesio, CE; Stanford, MR; Williamson, TH; Wong, R, 2010)
"Infections caused by cytomegalovirus (CMV) resistant in vitro to ganciclovir, defined as requiring greater than 6 mumols of ganciclovir for ED50 have developed in some AIDS patients with progressive CMV retinitis despite chronic ganciclovir therapy."7.68Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS. ( Drew, WL; Feinberg, J; Jacobson, MA; Miner, RD; O'Donnell, JJ; Parenti, D; Whitmore, PV, 1991)
"Foscarnet is an investigational antiviral agent that has been used effectively in the treatment of cytomegalovirus (CMV) retinitis in AIDS patients."7.68Successful foscarnet therapy for cytomegalovirus retinitis in an AIDS patient undergoing hemodialysis: rationale for empiric dosing and plasma level monitoring. ( Gambertoglio, JG; Graziani, AL; Grunwald, JE; MacGregor, RR; Weiss, R, 1991)
"Foscarnet has a low solubility and a high degree of ionization at physiologic pH, requiring it to be administered in higher doses and larger volumes."6.38Approaches to the treatment of cytomegalovirus retinitis: ganciclovir and foscarnet. ( Jacobson, MA; O'Donnell, JJ, 1991)
"We treated a patient who had acquired immunodeficiency syndrome and cytomegalovirus retinitis of the left eye."5.28Intravitreal foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome. ( Chipont, E; Díaz-Llopis, M; España, E; Menezo, JL; Navea, A; Sanchez, S, 1992)
"After withdrawal from maintenance treatment, a relapse of cytomegalovirus retinitis occurred, which was again successfully treated with ganciclovir."5.282.5 years survival with sequential ganciclovir/foscarnet treatment in a patient with acquired immune deficiency syndrome and cytomegalovirus retinitis. ( Geier, SA; Goebel, FD; Klauss, V; Kronawitter, U; Matuschke, A, 1992)
"In a controlled trial of foscarnet in the treatment of cytomegalovirus (CMV) retinitis in patients with the acquired immunodeficiency syndrome (AIDS), patients with non-immediately sight-threatening lesions were randomized to receive immediate treatment with foscarnet or foscarnet treatment delayed until the first signs of retinitis progression."5.07Design of a randomized controlled trial of foscarnet in patients with cytomegalovirus retinitis associated with acquired immunodeficiency syndrome. ( Polis, MA, 1992)
"To evaluate foscarnet sodium in treating cytomegalovirus retinitis in patients with AIDS."5.07A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS. ( Baird, BF; Davey, RT; Davis, M; De Smet, MD; Falloon, J; Kovacs, JA; Palestine, AG; Polis, MA; Zunich, KM; Zurlo, JJ, 1991)
"The use of ganciclovir in the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS) is limited by marrow toxicity and by the development of resistance to this agent in CMV strains capable of causing progressive disease."4.78Maintenance therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: foscarnet. ( Jacobson, MA, 1992)
"Acute retinal necrosis secondary to HSV-2 tended to have persistent active retinitis with a higher rate of retinal detachment despite similar treatment protocols, suggesting that in some cases combination intravenous acyclovir and adjuvant intravitreal foscarnet injections are not sufficient."4.02ACUTE RETINAL NECROSIS: Difference in Outcome by Viral Type and Options for Antiviral Therapy. ( Botsford, BW; Eller, AW; Nguyen, VQ, 2021)
"To report use of intravenous foscarnet or cidofovir for the treatment of refractory acute retinal necrosis (ARN)."3.88Treatment of Refractory Acute Retinal Necrosis with Intravenous Foscarnet or Cidofovir. ( Barshak, MB; Durand, ML; Foster, CS; Kim, IK; Mali, JO; Scott, NL; Stryjewski, TP; Tobin, EH; Young, LH, 2018)
"To study the effects of intravitreal foscarnet and the clinical differences between varicella zoster virus (VZV) and herpes simplex virus (HSV) induced acute retinal necrosis (ARN)."3.76Acute retinal necrosis: the effects of intravitreal foscarnet and virus type on outcome. ( Graham, EM; Laidlaw, DA; Pavesio, CE; Stanford, MR; Williamson, TH; Wong, R, 2010)
"Sequential visual field testing is an extremely helpful adjunct to ophthalmoscopy and fundus photography in the management of cytomegalovirus (CMV) retinitis with the antiviral agents ganciclovir or foscarnet in patients with the acquired immune deficiency syndrome (AIDS)."3.68Visual field testing in the management of cytomegalovirus retinitis. ( Bachman, DM; Bruni, LM; DiGioia, RA; Harris, PJ; McMackin, CM; Pistole, MC; Thomas, RM; Ward, DJ, 1992)
"Infections caused by cytomegalovirus (CMV) resistant in vitro to ganciclovir, defined as requiring greater than 6 mumols of ganciclovir for ED50 have developed in some AIDS patients with progressive CMV retinitis despite chronic ganciclovir therapy."3.68Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS. ( Drew, WL; Feinberg, J; Jacobson, MA; Miner, RD; O'Donnell, JJ; Parenti, D; Whitmore, PV, 1991)
"Foscarnet is an investigational antiviral agent that has been used effectively in the treatment of cytomegalovirus (CMV) retinitis in AIDS patients."3.68Successful foscarnet therapy for cytomegalovirus retinitis in an AIDS patient undergoing hemodialysis: rationale for empiric dosing and plasma level monitoring. ( Gambertoglio, JG; Graziani, AL; Grunwald, JE; MacGregor, RR; Weiss, R, 1991)
"Foscarnet has a low solubility and a high degree of ionization at physiologic pH, requiring it to be administered in higher doses and larger volumes."2.38Approaches to the treatment of cytomegalovirus retinitis: ganciclovir and foscarnet. ( Jacobson, MA; O'Donnell, JJ, 1991)
" Myelosuppression may be further exacerbated in AIDS patients by such other agents as zidovudine or trimethoprim/sulfamethoxazole, often necessitating dosage reductions or discontinuation of these agents in patients receiving ganciclovir."2.38Foscarnet sodium. ( Baltz, JK; Minor, JR, 1991)
" While on maintenance dosing of oral valacyclovir, he experienced reactivation in the form of bilateral vasculitis, which was successfully managed once restarting therapeutic oral dosing."1.51Case Report: Varicella-zoster Encephalitis with Acute Retinal Necrosis and Oculomotor Nerve Palsy. ( Quan, SC; Skondra, D, 2019)
" Chronic suppression with oral antiviral therapy after ARN is recommended to prevent involvement of the contralateral eye, though there is no consensus on the duration and dosage of antivirals."1.51Acute retinal necrosis in a patient with remote severe herpes simplex encephalitis. ( Kobayashi, T; Meier, J; Sekar, P; Streit, J, 2019)
"Retinal detachment is the main complication."1.32[Acute retinal necrosis: clinical presentation, treatment, and prognosis in a series of 22 patients]. ( Laroche, L; Larricart, P; Metge, F; Monin, C; Morel, C; Roman, S; Scheer, S, 2004)
"Retinitis was clinically graded by indirect ophthalmoscopy, and the retinitis scores were compared across the treatment and control groups."1.30Treatment of herpes retinitis in an animal model with a sustained delivery antiviral drug, liposomal 1-O-octadecyl-SN-glycerol-3-phosphonoformate. ( Bergeron-Lynn, G; Chaidhawangul, S; Cheng, L; Freeman, WR; Gardner, MF; Hostetler, KY; Mach-Hofacre, B; Mueller, AJ; Ozerdem, U; Severson, GM, 1999)
"We treated a patient who had acquired immunodeficiency syndrome and cytomegalovirus retinitis of the left eye."1.28Intravitreal foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome. ( Chipont, E; Díaz-Llopis, M; España, E; Menezo, JL; Navea, A; Sanchez, S, 1992)
"After withdrawal from maintenance treatment, a relapse of cytomegalovirus retinitis occurred, which was again successfully treated with ganciclovir."1.282.5 years survival with sequential ganciclovir/foscarnet treatment in a patient with acquired immune deficiency syndrome and cytomegalovirus retinitis. ( Geier, SA; Goebel, FD; Klauss, V; Kronawitter, U; Matuschke, A, 1992)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's36 (61.02)18.2507
2000's8 (13.56)29.6817
2010's13 (22.03)24.3611
2020's2 (3.39)2.80

Authors

AuthorsStudies
Manikowski, A1
Verri, A1
Lossani, A1
Gebhardt, BM1
Gambino, J1
Focher, F1
Spadari, S1
Wright, GE1
Hafidi, M1
Janin-Manificat, H1
Denis, P1
Charleux, B1
Rabilloud, M1
Boibieux, A1
Burillon, C1
Kodjikian, L1
Frobert, E1
Pockar, S1
Jones, NP1
Chhabra, R1
Steeples, LR1
Botsford, BW1
Nguyen, VQ1
Eller, AW1
Ong, SS1
Postel, EA1
Quan, SC1
Skondra, D1
Kobayashi, T1
Sekar, P1
Meier, J1
Streit, J1
Or, C1
Press, N1
Forooghian, F1
Dokey, AT1
Haug, SJ1
McDonald, HR1
Cunningham, ET1
Lujan, BJ1
Fu, AD1
Jumper, JM1
Weissman, HM1
Biousse, V1
Schechter, MC1
Del Rio, C1
Yeh, S2
Le, TD1
Weisbrod, D1
Mandelcorn, ED1
Xu, K1
Chin, EK1
Mahajan, VB1
Almeida, DR1
Stryjewski, TP1
Scott, NL1
Barshak, MB1
Tobin, EH1
Mali, JO1
Young, LH1
Foster, CS1
Kim, IK1
Durand, ML1
Schoenberger, SD1
Kim, SJ2
Thorne, JE1
Mruthyunjaya, P1
Bakri, SJ1
Ehlers, JP1
Lo, WR1
Wong, R1
Pavesio, CE1
Laidlaw, DA1
Williamson, TH1
Graham, EM1
Stanford, MR1
Meghpara, B1
Sulkowski, G1
Kesen, MR1
Tessler, HH1
Goldstein, DA1
Gain, P1
Chiquet, C1
Thuret, G1
Drouet, E1
Antoine, JC1
Morel, C1
Metge, F1
Roman, S1
Scheer, S1
Larricart, P1
Monin, C1
Laroche, L1
Tran, TH1
Stanescu, D1
Caspers-Velu, L1
Rozenberg, F2
Liesnard, C1
Gaudric, A1
Lehoang, P2
Bodaghi, B2
Oberacher-Velten, IM1
Jonas, JB1
Jünemann, A1
Schmidt, B1
de Schryver, I1
Cassoux, N1
Michelson, S1
Kestelyn, P1
Davis, JL1
Irvine, AR1
Freeman, WR3
Pearson, PA1
Jaffe, GJ1
Ashton, P1
Brockmeyer, NH1
Hengge, UR1
Mertins, L1
Malessa, R1
Steinmetz, R1
Gooss, M1
Flores-Aguilar, M1
Kuppermann, BD1
Quiceno, JI2
Dankner, WM1
Wolf, DG1
Capparelli, EV1
Connor, JD1
Sherwood, CH1
Fullerton, S1
Gambertoglio, JG2
Patel, SS1
Rutzen, AR1
Marx, JL1
Thach, AB1
Chong, LP1
Rao, NA3
Moorthy, RS1
Weinberg, DV1
Teich, SA1
Berger, BB1
Minturn, JT1
Kumar, S1
Fowell, SM1
Loose, IA1
Jampol, LM2
Cheng, L1
Hostetler, KY1
Chaidhawangul, S1
Gardner, MF1
Ozerdem, U1
Bergeron-Lynn, G1
Mach-Hofacre, B1
Mueller, AJ1
Severson, GM1
Chakrabarti, S1
Collingham, KE1
Osman, H1
Fegan, CD1
Milligan, DW1
Healy, B1
Masur, H1
Heinemann, MH1
Polis, MA2
Jacobson, MA4
Jabs, DA1
Salit, IE1
Wilson, RJ1
Keefe, KS1
Peterson, TJ1
Wiley, CA1
Crapotta, J1
Listhaus, AD1
Bachman, DM1
Bruni, LM1
DiGioia, RA1
Harris, PJ1
McMackin, CM1
Pistole, MC1
Thomas, RM1
Ward, DJ1
Díaz-Llopis, M1
Chipont, E1
Sanchez, S1
España, E1
Navea, A1
Menezo, JL1
Geier, SA1
Klauss, V1
Matuschke, A1
Kronawitter, U1
Goebel, FD1
Morinelli, EN1
Dugel, PU1
Lee, M1
Klatt, EC1
Morris, DJ1
Drew, WL1
Feinberg, J1
O'Donnell, JJ2
Whitmore, PV1
Miner, RD1
Parenti, D1
MacGregor, RR1
Graziani, AL1
Weiss, R1
Grunwald, JE1
Palestine, AG1
De Smet, MD1
Baird, BF1
Falloon, J1
Kovacs, JA1
Davey, RT1
Zurlo, JJ1
Zunich, KM1
Davis, M1
Marwick, C1
Nightingale, SL1
Nelson, MR1
Barter, G1
Hawkins, D1
Gazzard, BG1
Henderly, DE1
Minor, JR1
Baltz, JK1
Farese, RV1
Schambelan, M1
Hollander, H1
Stringari, S1
Deray, G1
Katlama, C1
Dohin, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure[NCT00000691]Phase 2156 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for foscarnet and Eye Infections, Viral

ArticleYear
Bilateral central retinal artery occlusion associated with herpes simplex virus-associated acute retinal necrosis and meningitis: case report and literature review.
    Ophthalmic surgery, lasers & imaging retina, 2015, Volume: 46, Issue:2

    Topics: Antibodies, Viral; Antiviral Agents; Aqueous Humor; DNA, Viral; Drug Therapy, Combination; Eye Infec

2015
Diagnosis and Treatment of Acute Retinal Necrosis: A Report by the American Academy of Ophthalmology.
    Ophthalmology, 2017, Volume: 124, Issue:3

    Topics: Academies and Institutes; Acyclovir; Antiviral Agents; Aqueous Humor; Biomedical Technology; DNA, Vi

2017
Clinical characteristics of acute HSV-2 retinal necrosis.
    American journal of ophthalmology, 2004, Volume: 137, Issue:5

    Topics: Acyclovir; Adult; Antiviral Agents; Aqueous Humor; Child; DNA, Viral; Drug Therapy, Combination; Eye

2004
Retinal disease associated with AIDS.
    Australian and New Zealand journal of ophthalmology, 1993, Volume: 21, Issue:2

    Topics: AIDS-Related Opportunistic Infections; CD4-Positive T-Lymphocytes; Cytomegalovirus Infections; Eye I

1993
Characteristics of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome.
    The American journal of medicine, 1992, Feb-14, Volume: 92, Issue:2A

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Maintenance therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: foscarnet.
    The American journal of medicine, 1992, Feb-14, Volume: 92, Issue:2A

    Topics: Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, Combination; Eye Infections, Viral; Fosc

1992
Cytomegalovirus retinitis in AIDS.
    Journal of the American Optometric Association, 1992, Volume: 63, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Diagnosis, Differe

1992
Approaches to the treatment of cytomegalovirus retinitis: ganciclovir and foscarnet.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4 Suppl 1

    Topics: Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, Combination; Eye Infections, Viral; Fosc

1991
Diagnosis and treatment of cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4 Suppl 1

    Topics: Antiviral Agents; Cytomegalovirus Infections; Diagnosis, Differential; Eye Infections, Viral; Foscar

1991
Foscarnet sodium.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1991

Trials

2 trials available for foscarnet and Eye Infections, Viral

ArticleYear
Design of a randomized controlled trial of foscarnet in patients with cytomegalovirus retinitis associated with acquired immunodeficiency syndrome.
    The American journal of medicine, 1992, Feb-14, Volume: 92, Issue:2A

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Eye Infecti

1992
A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS.
    Annals of internal medicine, 1991, Nov-01, Volume: 115, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Eye Infecti

1991

Other Studies

47 other studies available for foscarnet and Eye Infections, Viral

ArticleYear
Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.
    Journal of medicinal chemistry, 2005, Jun-02, Volume: 48, Issue:11

    Topics: Animals; Antiviral Agents; Cloning, Molecular; Encephalitis, Herpes Simplex; Eye Infections, Viral;

2005
Acute Retinal Necrosis: Virological Features Using Quantitative Polymerase Chain Reaction, Therapeutic Management, and Clinical Outcomes.
    American journal of ophthalmology, 2019, Volume: 208

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Aqueous Humor; Cytomegalovirus Retinitis; DNA, Vir

2019
Detection of Pre-clinical Involvement of the Second Eye in Viral Acute Retinal Necrosis Using Optical Coherence Tomography.
    Ocular immunology and inflammation, 2022, Jan-02, Volume: 30, Issue:1

    Topics: Eye Infections, Viral; Foscarnet; Herpesvirus 3, Human; Humans; Male; Middle Aged; Retinal Necrosis

2022
ACUTE RETINAL NECROSIS: Difference in Outcome by Viral Type and Options for Antiviral Therapy.
    Retina (Philadelphia, Pa.), 2021, Jul-01, Volume: 41, Issue:7

    Topics: Acyclovir; Adult; Aged; Aged, 80 and over; Antiviral Agents; DNA, Viral; Eye Infections, Viral; Fema

2021
Sudden Unilateral Decrease in Vision in a Healthy Middle-aged Man.
    JAMA ophthalmology, 2018, 11-01, Volume: 136, Issue:11

    Topics: Antiviral Agents; Eye Infections, Viral; Fluorescein Angiography; Foscarnet; Herpes Simplex; Herpesv

2018
Case Report: Varicella-zoster Encephalitis with Acute Retinal Necrosis and Oculomotor Nerve Palsy.
    Optometry and vision science : official publication of the American Academy of Optometry, 2019, Volume: 96, Issue:5

    Topics: Aged; Antiviral Agents; Aqueous Humor; Cerebrospinal Fluid; Drug Therapy, Combination; Encephalitis,

2019
Acute retinal necrosis in a patient with remote severe herpes simplex encephalitis.
    BMJ case reports, 2019, May-27, Volume: 12, Issue:5

    Topics: Acute Disease; Acyclovir; Antiviral Agents; Diagnosis, Differential; Encephalitis, Herpes Simplex; E

2019
Acute retinal necrosis secondary to cytomegalovirus following successful treatment of cytomegalovirus anterior uveitis in an immunocompetent adult.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2013, Volume: 48, Issue:2

    Topics: Antiviral Agents; Aqueous Humor; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Drug Thera

2013
Acute retinal necrosis secondary to multidrug-resistant herpes simplex virus 2 in an immunocompetent adolescent.
    Retinal cases & brief reports, 2014,Fall, Volume: 8, Issue:4

    Topics: Adolescent; Antiviral Agents; Drug Resistance, Viral; Eye Infections, Viral; Foscarnet; Herpes Simpl

2014
Chorioretinitis with exudative retinal detachment secondary to varicella zoster virus.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2015, Volume: 50, Issue:5

    Topics: Acyclovir; Administration, Oral; Antiviral Agents; Chorioretinitis; Drug Combinations; Exudates and

2015
Intravitreal Foscarnet With Concurrent Silicone Oil Tamponade for Rhegmatogenous Retinal Detachment Secondary to Viral Retinitis.
    Retina (Philadelphia, Pa.), 2016, Volume: 36, Issue:11

    Topics: Antiviral Agents; Combined Modality Therapy; Endotamponade; Eye Infections, Viral; Foscarnet; Humans

2016
Treatment of Refractory Acute Retinal Necrosis with Intravenous Foscarnet or Cidofovir.
    Ocular immunology and inflammation, 2018, Volume: 26, Issue:2

    Topics: Aged; Aged, 80 and over; Antiviral Agents; Cidofovir; Cytosine; Eye Infections, Viral; Foscarnet; He

2018
Acute retinal necrosis.
    Ophthalmology, 2008, Volume: 115, Issue:6

    Topics: Acyclovir; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Eye Infections, Viral; Foscarnet

2008
Acute retinal necrosis: the effects of intravitreal foscarnet and virus type on outcome.
    Ophthalmology, 2010, Volume: 117, Issue:3

    Topics: Acyclovir; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Eye Infections, Vira

2010
Long-term follow-up of acute retinal necrosis.
    Retina (Philadelphia, Pa.), 2010, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Aged; Antiviral Agents; Child; Cytomegalovirus; Cytomegalovirus Infections; Drug

2010
Herpes simplex virus type 1 encephalitis associated with acute retinal necrosis syndrome in an immunocompetent patient.
    Acta ophthalmologica Scandinavica, 2002, Volume: 80, Issue:5

    Topics: Adult; Antiviral Agents; Aqueous Humor; Cerebrospinal Fluid; DNA, Viral; Encephalitis, Herpes Simple

2002
[Acute retinal necrosis: clinical presentation, treatment, and prognosis in a series of 22 patients].
    Journal francais d'ophtalmologie, 2004, Volume: 27, Issue:1

    Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Combi

2004
Bilateral optic neuropathy and unilateral tonic pupil associated with acute human herpesvirus 6 infection: a case report.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2005, Volume: 243, Issue:2

    Topics: Adult; Antibodies, Viral; Antiviral Agents; Eye Infections, Viral; Foscarnet; Herpesvirus 6, Human;

2005
Diagnosis and treatment of cytomegalovirus iridocyclitis without retinal necrosis.
    The British journal of ophthalmology, 2006, Volume: 90, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Chronic Disease; Cytomegalovirus; Cyto

2006
Intraocular sustained drug release devices.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Delayed-Action Preparations; Drug

1995
Intravitreal foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome.
    American journal of ophthalmology, 1993, May-15, Volume: 115, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Eye Infections, Viral; Foscarnet;

1993
Foscarnet treatment in various cytomegalovirus infections.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Colitis; Cytomegalovirus Infections; Eye Infections, Viral; Fiss

1993
Pathophysiology and treatment of clinically resistant cytomegalovirus retinitis.
    Ophthalmology, 1993, Volume: 100, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus; Cytomegalovirus Infections; Drug Resi

1993
Cytomegalovirus papillitis in patients with acquired immune deficiency syndrome. Visual prognosis of patients treated with ganciclovir and/or foscarnet.
    Ophthalmology, 1996, Volume: 103, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Cytomega

1996
Management of varicella zoster virus retinitis in AIDS.
    The British journal of ophthalmology, 1997, Volume: 81, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; AIDS-Related Opportunistic Infections; Analysi

1997
Drugs for non-HIV viral infections.
    The Medical letter on drugs and therapeutics, 1997, Aug-01, Volume: 39, Issue:1006

    Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cont

1997
Treatment of herpes retinitis in an animal model with a sustained delivery antiviral drug, liposomal 1-O-octadecyl-SN-glycerol-3-phosphonoformate.
    Retina (Philadelphia, Pa.), 1999, Volume: 19, Issue:4

    Topics: Animals; Antiviral Agents; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Eye I

1999
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections.
    Bone marrow transplantation, 2001, Volume: 28, Issue:9

    Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytos

2001
From the National Institutes of Health.
    JAMA, 1992, Jan-08, Volume: 267, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Arthr

1992
Foscarnet.
    The Medical letter on drugs and therapeutics, 1992, Jan-10, Volume: 34, Issue:861

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Clinical implications of herpesvirus infections in patients with AIDS. Introduction.
    The American journal of medicine, 1992, Feb-14, Volume: 92, Issue:2A

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Treatment of cytomegalovirus retinitis--1992.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Why was treatment of cytomegalovirus retinitis randomized?
    Annals of internal medicine, 1992, Apr-01, Volume: 116, Issue:7

    Topics: Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Viral; Foscarnet; Ganciclovir; Humans;

1992
Atypical healing of cytomegalovirus retinitis. Significance of persistent border opacification.
    Ophthalmology, 1992, Volume: 99, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections

1992
Visual field testing in the management of cytomegalovirus retinitis.
    Ophthalmology, 1992, Volume: 99, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Eye Infe

1992
Intravitreal foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome.
    American journal of ophthalmology, 1992, Dec-15, Volume: 114, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus Infections; Eye Infections, Viral; Follow

1992
2.5 years survival with sequential ganciclovir/foscarnet treatment in a patient with acquired immune deficiency syndrome and cytomegalovirus retinitis.
    German journal of ophthalmology, 1992, Volume: 1, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Cataract Extraction; Cytomegalovirus Infections; Drug Adminis

1992
Opportunistic intraocular infections in AIDS.
    Transactions of the American Ophthalmological Society, 1992, Volume: 90

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Choroiditis; Cyto

1992
Treatment of CMV retinitis.
    Lancet (London, England), 1992, Jan-25, Volume: 339, Issue:8787

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS.
    The Journal of infectious diseases, 1991, Volume: 163, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infect

1991
Successful foscarnet therapy for cytomegalovirus retinitis in an AIDS patient undergoing hemodialysis: rationale for empiric dosing and plasma level monitoring.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adult; Antiviral Agents; Cytomegalovirus In

1991
National Eye Institute issues clinical alert about CMV retinitis in AIDS.
    JAMA, 1991, Nov-20, Volume: 266, Issue:19

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1991
From the Food and Drug Administration.
    JAMA, 1991, Dec-18, Volume: 266, Issue:23

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1991
Simultaneous treatment of cytomegalovirus retinitis with ganciclovir and foscarnet.
    Lancet (London, England), 1991, Jul-27, Volume: 338, Issue:8761

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Eye Infecti

1991
Seeing the way forward for treatment of CMV retinitis.
    Lancet (London, England), 1991, Dec-14, Volume: 338, Issue:8781

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Infe

1991
Nephrogenic diabetes insipidus associated with foscarnet treatment of cytomegalovirus retinitis.
    Annals of internal medicine, 1990, Jun-15, Volume: 112, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Diabetes In

1990
Prevention of foscarnet nephrotoxicity.
    Annals of internal medicine, 1990, Aug-15, Volume: 113, Issue:4

    Topics: Adult; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Viral; Female; Fluid Therapy; F

1990