Page last updated: 2024-10-27

foscarnet and Esophagitis

foscarnet has been researched along with Esophagitis in 7 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Esophagitis: INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"Although several uncontrolled studies have shown that the response rate to ganciclovir and foscarnet for all forms of cytomegalovirus (CMV) infection in immunocompromised patients is almost similar, to date, no controlled clinical trial has been specifically designed to compare these two agents in the treatment of CMV esophagitis."9.08Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group. ( Bianchi Porro, G; Parente, F, 1998)
"CMV esophagitis has a favorable response to induction ganciclovir therapy, and a long-term remission may occur after induction therapy alone."7.69Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome. ( Schwartz, DA; Straub, RF; Wilcox, CM, 1995)
"A 41-year-old recipient of matched unrelated BMT acquired a severe mucocutaneous herpes simplex virus (HSV) type I infection during acyclovir prophylaxis."7.68Successful foscarnet therapy for acyclovir-resistant mucocutaneous infection with herpes simplex virus in a recipient of allogeneic BMT. ( Cornelissen, JJ; de Gast, GC; Dekker, AW; Lepoutre, J; Rozenberg-Arska, M; Smit, J; Verdonck, LF, 1993)
"Although several uncontrolled studies have shown that the response rate to ganciclovir and foscarnet for all forms of cytomegalovirus (CMV) infection in immunocompromised patients is almost similar, to date, no controlled clinical trial has been specifically designed to compare these two agents in the treatment of CMV esophagitis."5.08Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group. ( Bianchi Porro, G; Parente, F, 1998)
"CMV esophagitis has a favorable response to induction ganciclovir therapy, and a long-term remission may occur after induction therapy alone."3.69Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome. ( Schwartz, DA; Straub, RF; Wilcox, CM, 1995)
"A 41-year-old recipient of matched unrelated BMT acquired a severe mucocutaneous herpes simplex virus (HSV) type I infection during acyclovir prophylaxis."3.68Successful foscarnet therapy for acyclovir-resistant mucocutaneous infection with herpes simplex virus in a recipient of allogeneic BMT. ( Cornelissen, JJ; de Gast, GC; Dekker, AW; Lepoutre, J; Rozenberg-Arska, M; Smit, J; Verdonck, LF, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wilcox, CM1
Straub, RF1
Schwartz, DA1
Poles, MA1
McMeeking, AA1
Scholes, JV1
Dieterich, DT1
Verdonck, LF1
Cornelissen, JJ1
Smit, J1
Lepoutre, J1
de Gast, GC1
Dekker, AW1
Rozenberg-Arska, M1
Nelson, MR1
Hawkins, DA1
Gazzard, BG1
Brown, DL1
Sather, S1
Cheitlin, MD1
Len, O1
de Otero, J1
Ribera, E1
OcaƱa, I1
Parente, F1
Bianchi Porro, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005228]0 participants Observational1988-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for foscarnet and Esophagitis

ArticleYear
Foscarnet in the treatment of cytomegalovirus esophagitis.
    The American journal of medicine, 1993, Volume: 94, Issue:4

    Topics: Cytomegalovirus Infections; Esophagitis; Foscarnet; HIV Seropositivity; HIV-1; Humans

1993
Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Biopsy; Cytomegalovirus Infections; Esophagitis; Foscarnet; G

1998

Other Studies

5 other studies available for foscarnet and Esophagitis

ArticleYear
Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome.
    The American journal of medicine, 1995, Volume: 98, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Drug Administration Schedu

1995
Actinomyces infection of a cytomegalovirus esophageal ulcer in two patients with acquired immunodeficiency syndrome.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:9

    Topics: Actinomycosis; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Esophageal

1994
Successful foscarnet therapy for acyclovir-resistant mucocutaneous infection with herpes simplex virus in a recipient of allogeneic BMT.
    Bone marrow transplantation, 1993, Volume: 11, Issue:2

    Topics: Acyclovir; Adult; Animals; Bone Marrow Transplantation; Chlorocebus aethiops; Esophagitis; Foscarnet

1993
Reversible cardiac dysfunction associated with foscarnet therapy for cytomegalovirus esophagitis in an AIDS patient.
    American heart journal, 1993, Volume: 125, Issue:5 Pt 1

    Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; AIDS-Related Opportunistic Infections; Cyt

1993
[Ulcer in the urethral meatus and HIV infection].
    Enfermedades infecciosas y microbiologia clinica, 1995, Volume: 13, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Drug Eru

1995