foscarnet has been researched along with Esophagitis in 7 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Esophagitis: INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although several uncontrolled studies have shown that the response rate to ganciclovir and foscarnet for all forms of cytomegalovirus (CMV) infection in immunocompromised patients is almost similar, to date, no controlled clinical trial has been specifically designed to compare these two agents in the treatment of CMV esophagitis." | 9.08 | Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group. ( Bianchi Porro, G; Parente, F, 1998) |
| "CMV esophagitis has a favorable response to induction ganciclovir therapy, and a long-term remission may occur after induction therapy alone." | 7.69 | Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome. ( Schwartz, DA; Straub, RF; Wilcox, CM, 1995) |
| "A 41-year-old recipient of matched unrelated BMT acquired a severe mucocutaneous herpes simplex virus (HSV) type I infection during acyclovir prophylaxis." | 7.68 | Successful foscarnet therapy for acyclovir-resistant mucocutaneous infection with herpes simplex virus in a recipient of allogeneic BMT. ( Cornelissen, JJ; de Gast, GC; Dekker, AW; Lepoutre, J; Rozenberg-Arska, M; Smit, J; Verdonck, LF, 1993) |
| "Although several uncontrolled studies have shown that the response rate to ganciclovir and foscarnet for all forms of cytomegalovirus (CMV) infection in immunocompromised patients is almost similar, to date, no controlled clinical trial has been specifically designed to compare these two agents in the treatment of CMV esophagitis." | 5.08 | Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group. ( Bianchi Porro, G; Parente, F, 1998) |
| "CMV esophagitis has a favorable response to induction ganciclovir therapy, and a long-term remission may occur after induction therapy alone." | 3.69 | Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome. ( Schwartz, DA; Straub, RF; Wilcox, CM, 1995) |
| "A 41-year-old recipient of matched unrelated BMT acquired a severe mucocutaneous herpes simplex virus (HSV) type I infection during acyclovir prophylaxis." | 3.68 | Successful foscarnet therapy for acyclovir-resistant mucocutaneous infection with herpes simplex virus in a recipient of allogeneic BMT. ( Cornelissen, JJ; de Gast, GC; Dekker, AW; Lepoutre, J; Rozenberg-Arska, M; Smit, J; Verdonck, LF, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilcox, CM | 1 |
| Straub, RF | 1 |
| Schwartz, DA | 1 |
| Poles, MA | 1 |
| McMeeking, AA | 1 |
| Scholes, JV | 1 |
| Dieterich, DT | 1 |
| Verdonck, LF | 1 |
| Cornelissen, JJ | 1 |
| Smit, J | 1 |
| Lepoutre, J | 1 |
| de Gast, GC | 1 |
| Dekker, AW | 1 |
| Rozenberg-Arska, M | 1 |
| Nelson, MR | 1 |
| Hawkins, DA | 1 |
| Gazzard, BG | 1 |
| Brown, DL | 1 |
| Sather, S | 1 |
| Cheitlin, MD | 1 |
| Len, O | 1 |
| de Otero, J | 1 |
| Ribera, E | 1 |
| Ocaña, I | 1 |
| Parente, F | 1 |
| Bianchi Porro, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00005228] | 0 participants | Observational | 1988-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for foscarnet and Esophagitis
| Article | Year |
|---|---|
Foscarnet in the treatment of cytomegalovirus esophagitis.
Topics: Cytomegalovirus Infections; Esophagitis; Foscarnet; HIV Seropositivity; HIV-1; Humans | 1993 |
Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group.
Topics: AIDS-Related Opportunistic Infections; Biopsy; Cytomegalovirus Infections; Esophagitis; Foscarnet; G | 1998 |
5 other studies available for foscarnet and Esophagitis
| Article | Year |
|---|---|
Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome.
Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Drug Administration Schedu | 1995 |
Actinomyces infection of a cytomegalovirus esophageal ulcer in two patients with acquired immunodeficiency syndrome.
Topics: Actinomycosis; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Esophageal | 1994 |
Successful foscarnet therapy for acyclovir-resistant mucocutaneous infection with herpes simplex virus in a recipient of allogeneic BMT.
Topics: Acyclovir; Adult; Animals; Bone Marrow Transplantation; Chlorocebus aethiops; Esophagitis; Foscarnet | 1993 |
Reversible cardiac dysfunction associated with foscarnet therapy for cytomegalovirus esophagitis in an AIDS patient.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; AIDS-Related Opportunistic Infections; Cyt | 1993 |
[Ulcer in the urethral meatus and HIV infection].
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Drug Eru | 1995 |