Page last updated: 2024-10-27

foscarnet and Encephalitis, Herpes Simplex

foscarnet has been researched along with Encephalitis, Herpes Simplex in 10 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Encephalitis, Herpes Simplex: An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)

Research Excerpts

ExcerptRelevanceReference
"Acyclovir resistance is rarely seen in herpes simplex virus (HSV) type I encephalitis."7.85Acyclovir resistance in herpes simplex virus type I encephalitis: a case report. ( Beer, R; Bergmann, M; Helbok, R; Kofler, M; Pfausler, B; Schmutzhard, E, 2017)
"Foscarnet treatment was initiated in place of acyclovir and his consciousness improved, with a slight improvement in visual acuity."6.55Acyclovir resistant acute herpes simplex encephalitis associated with acute retinal necrosis: A case report and review of the literature. ( Aoki, M; Fukae, J; Kimura, S; Nabeshima, K; Ogura, H; Tsuboi, Y, 2017)
"Acyclovir resistance is rarely seen in herpes simplex virus (HSV) type I encephalitis."3.85Acyclovir resistance in herpes simplex virus type I encephalitis: a case report. ( Beer, R; Bergmann, M; Helbok, R; Kofler, M; Pfausler, B; Schmutzhard, E, 2017)
"Foscarnet treatment was initiated in place of acyclovir and his consciousness improved, with a slight improvement in visual acuity."2.55Acyclovir resistant acute herpes simplex encephalitis associated with acute retinal necrosis: A case report and review of the literature. ( Aoki, M; Fukae, J; Kimura, S; Nabeshima, K; Ogura, H; Tsuboi, Y, 2017)
"Acyclovir is the treatment of choice of HSE since the 1980s."1.51Acyclovir Unresponsive Herpes Simplex Encephalitis in a child successfully treated with the addition of Foscarnet: Case report. ( Aydin Teke, T; Gayretli Aydin, ZG; Genc Sel, C; Kaman, A; Tanir, G; Tasci Yıldız, Y, 2019)
" Chronic suppression with oral antiviral therapy after ARN is recommended to prevent involvement of the contralateral eye, though there is no consensus on the duration and dosage of antivirals."1.51Acute retinal necrosis in a patient with remote severe herpes simplex encephalitis. ( Kobayashi, T; Meier, J; Sekar, P; Streit, J, 2019)
"We present a patient with polymorphic ventricular tachycardia and subsequent ventricular fibrillation with acquired long QT syndrome secondary to herpes encephalitis."1.38Polymorphic ventricular tachycardia in a patient with herpes encephalitis. ( Blaschke, D; Boldt, LH; Haverkamp, W; Huemer, M; Parwani, A; Rolf, S; Wutzler, A, 2012)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Manikowski, A1
Verri, A1
Lossani, A1
Gebhardt, BM1
Gambino, J1
Focher, F1
Spadari, S1
Wright, GE1
Toro, J1
Rivera, JS1
Moutran-Barroso, H1
Valencia-Enciso, N1
Sagnier, S1
Poli, M1
Debruxelles, S1
Renou, P1
Rouanet, F1
Sibon, I1
Ogura, H1
Fukae, J1
Kimura, S1
Aoki, M1
Nabeshima, K1
Tsuboi, Y1
Gayretli Aydin, ZG1
Tanir, G1
Genc Sel, C1
Tasci Yıldız, Y1
Aydin Teke, T1
Kaman, A1
Kobayashi, T1
Sekar, P1
Meier, J1
Streit, J1
Schepers, K1
Hernandez, A1
Andrei, G1
Gillemot, S1
Fiten, P1
Opdenakker, G1
Bier, JC1
David, P1
Delforge, ML1
Jacobs, F1
Snoeck, R1
Bergmann, M1
Beer, R1
Kofler, M1
Helbok, R1
Pfausler, B1
Schmutzhard, E1
Huemer, M1
Boldt, LH1
Wutzler, A1
Parwani, A1
Rolf, S1
Blaschke, D1
Haverkamp, W1
Gain, P1
Chiquet, C1
Thuret, G1
Drouet, E1
Antoine, JC1

Reviews

1 review available for foscarnet and Encephalitis, Herpes Simplex

ArticleYear
Acyclovir resistant acute herpes simplex encephalitis associated with acute retinal necrosis: A case report and review of the literature.
    Rinsho shinkeigaku = Clinical neurology, 2017, 05-27, Volume: 57, Issue:5

    Topics: Acute Disease; Acyclovir; Antiviral Agents; Disease Progression; Drug Resistance, Viral; Encephaliti

2017

Other Studies

9 other studies available for foscarnet and Encephalitis, Herpes Simplex

ArticleYear
Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.
    Journal of medicinal chemistry, 2005, Jun-02, Volume: 48, Issue:11

    Topics: Animals; Antiviral Agents; Cloning, Molecular; Encephalitis, Herpes Simplex; Eye Infections, Viral;

2005
Acute HSV and anti-NMDA encephalitis occurring as a neurosurgical complication.
    BMJ case reports, 2021, May-26, Volume: 14, Issue:5

    Topics: Acyclovir; Adult; Antiviral Agents; Encephalitis, Herpes Simplex; Foscarnet; Humans; Male; Neoplasm

2021
High-dose acyclovir combined with foscavir (foscarnet) in the management of severe herpes simplex virus meningoencephalitis.
    Revue neurologique, 2017, Volume: 173, Issue:4

    Topics: Acyclovir; Adolescent; Antiviral Agents; Brain; Drug Therapy, Combination; Encephalitis, Herpes Simp

2017
Acyclovir Unresponsive Herpes Simplex Encephalitis in a child successfully treated with the addition of Foscarnet: Case report.
    Archivos argentinos de pediatria, 2019, 02-01, Volume: 117, Issue:1

    Topics: Acyclovir; Antiviral Agents; Child; Drug Combinations; Drug Resistance, Viral; Encephalitis, Herpes

2019
Acute retinal necrosis in a patient with remote severe herpes simplex encephalitis.
    BMJ case reports, 2019, May-27, Volume: 12, Issue:5

    Topics: Acute Disease; Acyclovir; Antiviral Agents; Diagnosis, Differential; Encephalitis, Herpes Simplex; E

2019
Acyclovir-resistant herpes simplex encephalitis in a patient treated with anti-tumor necrosis factor-α monoclonal antibodies.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2014, Volume: 59, Issue:1

    Topics: Acyclovir; Adalimumab; Antibodies, Monoclonal, Humanized; Cerebrospinal Fluid; Drug Resistance, Vira

2014
Acyclovir resistance in herpes simplex virus type I encephalitis: a case report.
    Journal of neurovirology, 2017, Volume: 23, Issue:2

    Topics: Acyclovir; Antiviral Agents; Disease Progression; Drug Resistance, Viral; Drug Substitution; Encepha

2017
Polymorphic ventricular tachycardia in a patient with herpes encephalitis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012, Volume: 19, Issue:3

    Topics: Acute Disease; Acyclovir; Antiviral Agents; Defibrillators, Implantable; Electrocardiography; Enceph

2012
Herpes simplex virus type 1 encephalitis associated with acute retinal necrosis syndrome in an immunocompetent patient.
    Acta ophthalmologica Scandinavica, 2002, Volume: 80, Issue:5

    Topics: Adult; Antiviral Agents; Aqueous Humor; Cerebrospinal Fluid; DNA, Viral; Encephalitis, Herpes Simple

2002