Page last updated: 2024-10-27

foscarnet and EBV Infections

foscarnet has been researched along with EBV Infections in 9 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Research Excerpts

ExcerptRelevanceReference
" Herpes simplex virus (HSV) reactivations are usually prevented by acyclovir (ACV) prophylaxis, whereas cidofovir (CDV) has been used off indication to manage AdV infections."7.83Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation. ( Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S, 2016)
"The lymphoproliferative disorders are usually treated with a combination of cytotoxic drugs, and virustatic medication is thought to be ineffective."5.31Regression of Epstein-Barr virus-associated lymphoproliferative disorders in patients with acquired immunodeficiency syndrome during therapy with foscarnet. ( Delecluse, HJ; Huhn, D; Ruhnke, M; Schneider, U; Stein, H, 2000)
" Herpes simplex virus (HSV) reactivations are usually prevented by acyclovir (ACV) prophylaxis, whereas cidofovir (CDV) has been used off indication to manage AdV infections."3.83Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation. ( Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S, 2016)
"EBV retinitis was diagnosed based on EBV-positive (9."1.62Effects of intraocular treatments for Epstein-Barr virus (EBV) retinitis: A case report. ( Komoto, T; Mushiga, Y; Nagai, N; Ozawa, Y, 2021)
"Chronic active EBV infections (CAEBV) are often causative of malignant lymphoproliferative disorders, such as natural killer (NK) cell-lineage granular lymphocyte proliferative disorders (NK-GLPD), which are refractory to several conventional chemotherapies and usually show a poor prognosis."1.32Possibility of preventive treatment for EBV-associated NK cell-lineage proliferative disorders. ( Ishii, M; Ishii, T; Kawase, I; Kimura, H; Mori, KL; Morishima, T; Ohshima, S; Saeki, Y; Yamaguchi, N, 2003)
"Treatment with foscarnet, an inhibitor of viral-DNA polymerase, in three patients with EBV-associated post-transplant lymphoproliferative disease (PTLD) after heart (n = 2) and heart/kidney transplantation (n = 1), who did not respond to, or were not eligible for reduction of immunosuppression, resulted in complete remission (48+, 27 and 15 months respectively)."1.31Identification of early antigen BZLF1/ZEBRA protein of Epstein-Barr virus can predict the effectiveness of antiviral treatment in patients with post-transplant lymphoproliferative disease. ( Anagnostopoulos, I; Hummel, MW; Jonas, S; Oertel, SH; Riess, HB, 2002)
" Long-term administration (>1 year) of high-dose acyclovir or similar agents with anti-EBV activity may prevent NHL in patients with AIDS."1.31Value of long-term administration of acyclovir and similar agents for protecting against AIDS-related lymphoma: case-control and historical cohort studies. ( Fong, IW; Fong, MW; Ho, J; Lo, B; Toy, C, 2000)
"The lymphoproliferative disorders are usually treated with a combination of cytotoxic drugs, and virustatic medication is thought to be ineffective."1.31Regression of Epstein-Barr virus-associated lymphoproliferative disorders in patients with acquired immunodeficiency syndrome during therapy with foscarnet. ( Delecluse, HJ; Huhn, D; Ruhnke, M; Schneider, U; Stein, H, 2000)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (77.78)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Mushiga, Y1
Komoto, T1
Nagai, N1
Ozawa, Y1
Voigt, S1
Hofmann, J1
Edelmann, A1
Sauerbrei, A1
Kühl, JS1
Oertel, SH1
Anagnostopoulos, I1
Hummel, MW1
Jonas, S1
Riess, HB1
Ishii, M1
Yamaguchi, N1
Ohshima, S1
Ishii, T1
Mori, KL1
Kimura, H1
Morishima, T1
Kawase, I1
Saeki, Y1
Tan, HH1
Goh, CL1
Zhang, SH1
Zhou, XG1
Yu, XM1
Wang, C1
Huang, SF1
Fong, IW1
Ho, J1
Toy, C1
Lo, B1
Fong, MW1
Schneider, U1
Ruhnke, M1
Delecluse, HJ1
Stein, H1
Huhn, D1
Schramm, C1
Schlaak, JF1
Galle, PR1

Reviews

1 review available for foscarnet and EBV Infections

ArticleYear
Viral infections affecting the skin in organ transplant recipients: epidemiology and current management strategies.
    American journal of clinical dermatology, 2006, Volume: 7, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Ad

2006

Other Studies

8 other studies available for foscarnet and EBV Infections

ArticleYear
Effects of intraocular treatments for Epstein-Barr virus (EBV) retinitis: A case report.
    Medicine, 2021, Dec-03, Volume: 100, Issue:48

    Topics: Adult; Epstein-Barr Virus Infections; Female; Foscarnet; Herpesvirus 4, Human; Humans; Methotrexate;

2021
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5

    Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Chi

2016
Identification of early antigen BZLF1/ZEBRA protein of Epstein-Barr virus can predict the effectiveness of antiviral treatment in patients with post-transplant lymphoproliferative disease.
    British journal of haematology, 2002, Volume: 118, Issue:4

    Topics: Adult; Antiviral Agents; DNA-Binding Proteins; Epstein-Barr Virus Infections; Foscarnet; Gene Rearra

2002
Possibility of preventive treatment for EBV-associated NK cell-lineage proliferative disorders.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:3

    Topics: Adolescent; Animals; Antiviral Agents; Cell Division; Chronic Disease; Culicidae; Epstein-Barr Virus

2003
[Post-transplant lymphoproliferative disorders following allogenic bone marrow transplantation].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2005, Volume: 34, Issue:12

    Topics: Adult; Antigens, CD20; Antiviral Agents; Bone Marrow Transplantation; CD3 Complex; Epstein-Barr Viru

2005
Value of long-term administration of acyclovir and similar agents for protecting against AIDS-related lymphoma: case-control and historical cohort studies.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:5

    Topics: Acyclovir; Adult; Antiviral Agents; Case-Control Studies; Cohort Studies; Drug Therapy, Combination;

2000
Regression of Epstein-Barr virus-associated lymphoproliferative disorders in patients with acquired immunodeficiency syndrome during therapy with foscarnet.
    Annals of hematology, 2000, Volume: 79, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Epstein-Barr Virus Infections; Foscarne

2000
Rapid development of Epstein-Barr virus-associated Hodgkin's disease after cessation of foscarnet therapy in an HIV-infected patient.
    International journal of STD & AIDS, 2000, Volume: 11, Issue:9

    Topics: Antiviral Agents; Epstein-Barr Virus Infections; Foscarnet; HIV Infections; Hodgkin Disease; Humans;

2000