foscarnet has been researched along with Disease Models, Animal in 16 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of sodium lauryl sulfate (SLS) on the efficacies of topical gel formulations of foscarnet against herpes simplex virus type 1 (HSV-1) cutaneous infection has been evaluated in mice." | 7.70 | Sodium lauryl sulfate increases the efficacy of a topical formulation of foscarnet against herpes simplex virus type 1 cutaneous lesions in mice. ( Bergeron, MG; Cormier, H; Désormeaux, A; Gourde, P; Juhász, J; Lamontagne, J; Piret, J, 2000) |
| "The influence of sodium lauryl sulfate (SLS) on the efficacies of topical gel formulations of foscarnet against herpes simplex virus type 1 (HSV-1) cutaneous infection has been evaluated in mice." | 3.70 | Sodium lauryl sulfate increases the efficacy of a topical formulation of foscarnet against herpes simplex virus type 1 cutaneous lesions in mice. ( Bergeron, MG; Cormier, H; Désormeaux, A; Gourde, P; Juhász, J; Lamontagne, J; Piret, J, 2000) |
| "The herpesvirus DNA polymerase inhibitor foscarnet, applied topically, and the anti-herpesvirus guanosine analogue buciclovir, given orally, decreased virus replication and disease development in primary skin infections of mice caused by herpes simplex virus type 1 (HSV-1)." | 3.67 | Limited efficacy of inhibitors of herpes simplex virus DNA synthesis in murine models of recrudescent disease. ( Datema, R; Ericson, AC; Kristofferson, A; Sohl-Akerlund, A, 1988) |
| "Retinitis was clinically graded by indirect ophthalmoscopy, and the retinitis scores were compared across the treatment and control groups." | 1.30 | Treatment of herpes retinitis in an animal model with a sustained delivery antiviral drug, liposomal 1-O-octadecyl-SN-glycerol-3-phosphonoformate. ( Bergeron-Lynn, G; Chaidhawangul, S; Cheng, L; Freeman, WR; Gardner, MF; Hostetler, KY; Mach-Hofacre, B; Mueller, AJ; Ozerdem, U; Severson, GM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Uwai, Y | 1 |
| Kondo, R | 1 |
| Suzuki, T | 1 |
| Kawasaki, T | 1 |
| Nabekura, T | 1 |
| Hsu, YJ | 1 |
| Hsu, SC | 1 |
| Huang, SM | 1 |
| Lee, HS | 1 |
| Lin, SH | 1 |
| Tsai, CS | 1 |
| Shih, CC | 1 |
| Lin, CY | 1 |
| Zeng, M | 1 |
| Wang, X | 2 |
| Zhao, X | 1 |
| Andrei, G | 1 |
| Fiten, P | 1 |
| Froeyen, M | 1 |
| De Clercq, E | 1 |
| Opdenakker, G | 1 |
| Snoeck, R | 1 |
| Lucia, HL | 1 |
| Griffith, BP | 1 |
| Hsiung, GD | 1 |
| Loghman-Adham, M | 1 |
| Motock, GT | 1 |
| Brooks, DP | 1 |
| Ali, SM | 1 |
| Contino, LC | 1 |
| Stack, E | 1 |
| Fredrickson, TA | 1 |
| Feild, J | 1 |
| Edwards, RM | 1 |
| Awan, AR | 2 |
| Harmenberg, J | 2 |
| Kristofferson, A | 2 |
| Field, HJ | 2 |
| Flink, O | 1 |
| Cheng, L | 1 |
| Hostetler, KY | 1 |
| Chaidhawangul, S | 1 |
| Gardner, MF | 1 |
| Ozerdem, U | 1 |
| Bergeron-Lynn, G | 1 |
| Mach-Hofacre, B | 1 |
| Mueller, AJ | 1 |
| Severson, GM | 1 |
| Freeman, WR | 1 |
| Piret, J | 1 |
| Désormeaux, A | 1 |
| Cormier, H | 1 |
| Lamontagne, J | 1 |
| Gourde, P | 1 |
| Juhász, J | 1 |
| Bergeron, MG | 1 |
| Bernstein, DI | 1 |
| Ireland, J | 1 |
| Bourne, N | 1 |
| Debs, RJ | 1 |
| Montgomery, AB | 1 |
| Brunette, EN | 1 |
| DeBruin, M | 1 |
| Shanley, JD | 1 |
| Ericson, AC | 2 |
| Sohl-Akerlund, A | 1 |
| Datema, R | 2 |
| Ulbricht, A | 1 |
| Färber, I | 1 |
| Wutzler, P | 1 |
| van Genderen, J | 1 |
| Wolthuis, OL | 1 |
| Ariens, AT | 1 |
16 other studies available for foscarnet and Disease Models, Animal
| Article | Year |
|---|---|
Potent Inhibition of Biphasic Tubular Reabsorption of Lithium by Acetazolamide and Foscarnet in Rats.
Topics: Acetazolamide; Animals; Antiviral Agents; Disease Models, Animal; Diuretics; Drug Interactions; Fosc | 2020 |
Hyperphosphatemia induces protective autophagy in endothelial cells through the inhibition of Akt/mTOR signaling.
Topics: Adenine; Animals; Autophagy; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; En | 2015 |
Effects of phosphonoformic acid and renagel on renal type IIa sodium-dependent phosphate cotransporter mRNA expression in hyperphosphatemia rats.
Topics: Animals; Chelating Agents; Disease Models, Animal; Follow-Up Studies; Foscarnet; Gene Expression Reg | 2012 |
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
Topics: Adenine; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Anima | 2007 |
Effect of acyclovir and phosphonoformate on cytomegalovirus infection in guinea pigs.
Topics: Acyclovir; Animals; Antiviral Agents; Cytomegalovirus Infections; Disease Models, Animal; Foscarnet; | 1984 |
Use of phosphonoformic acid to induce phosphaturia in chronic renal failure in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Disease Models, Animal; Foscarnet; Glomerular F | 1996 |
Phosphate excretion and phosphate transporter messenger RNA in uremic rats treated with phosphonoformic acid.
Topics: Animals; Carrier Proteins; Disease Models, Animal; Foscarnet; Kidney Diseases; Male; Nephrectomy; Ph | 1997 |
Herpes simplex virus zosteriform lesions with adoptive transfer of immune cells: a murine model which mimics human recurrent disease.
Topics: Administration, Topical; Adoptive Transfer; Animals; Antiviral Agents; Cell Line; Cricetinae; Diseas | 1998 |
Combinations of antiviral and anti-inflammatory preparations for the topical treatment of herpes simplex virus assessed using a murine zosteriform infection model.
Topics: Administration, Topical; Adoptive Transfer; Animals; Anti-Inflammatory Agents; Antiviral Agents; Dis | 1998 |
Treatment of herpes retinitis in an animal model with a sustained delivery antiviral drug, liposomal 1-O-octadecyl-SN-glycerol-3-phosphonoformate.
Topics: Animals; Antiviral Agents; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Eye I | 1999 |
Sodium lauryl sulfate increases the efficacy of a topical formulation of foscarnet against herpes simplex virus type 1 cutaneous lesions in mice.
Topics: Administration, Topical; Animals; Antiviral Agents; Cell Survival; Chemistry, Pharmaceutical; Chloro | 2000 |
Pathogenesis of acyclovir-resistant herpes simplex type 2 isolates in animal models of genital herpes: models for antiviral evaluations.
Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Disease Models, Animal; Drug Resistance, | 2000 |
Aerosol administration of antiviral agents to treat lung infection due to murine cytomegalovirus.
Topics: Acyclovir; Administration, Oral; Aerosols; Animals; Antiviral Agents; Cytomegalovirus Infections; Di | 1988 |
Limited efficacy of inhibitors of herpes simplex virus DNA synthesis in murine models of recrudescent disease.
Topics: Acyclovir; Administration, Oral; Administration, Topical; Animals; Antiviral Agents; Disease Models, | 1988 |
Herpes simplex virus hepatitis in mice: effects of treatment with trisodium phosphonoformate.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Foscarnet; Hepatitis, Viral, Animal; Herpes Simpl | 1985 |
The effects of topical foscarnet in a new model of herpes simplex skin infection.
Topics: Administration, Cutaneous; Animals; Antiviral Agents; Disease Models, Animal; Foscarnet; Herpes Simp | 1987 |