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foscarnet and Cytomegaloviral Retinitis

foscarnet has been researched along with Cytomegaloviral Retinitis in 191 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Research Excerpts

ExcerptRelevanceReference
"The clinical significance of cytomegalovirus (CMV) foscarnet resistance was studied in patients with acquired immunodeficiency syndrome and CMV retinitis."9.10Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. ( Chou, S; Crumpacker, C; Forman, MS; Jabs, DA; Lurain, NS; Martin, BK; Weinberg, A, 2003)
"Two hundred thirty-four patients with the acquired immunodeficiency syndrome and previously untreated cytomegalovirus retinitis at 11 university centers were randomly assigned to receive intravenously either foscarnet (n = 107) or ganciclovir (n = 127)."9.08Morbidity and toxic effects associated with ganciclovir or foscarnet therapy in a randomized cytomegalovirus retinitis trial. Studies of ocular complications of AIDS Research Group, in collaboration with the AIDS Clinical Trials Group. ( , 1995)
"The Cytomegalovirus Retinitis Retreatment Trial was a multicenter clinical trial designed to evaluate three treatments for the treatment of relapsed CMV retinitis; (1) foscarnet; (2) 'high-dose' ganciclovir, and (3) combination foscarnet and ganciclovir."9.08Design of clinical trials for drug combinations: cytomegalovirus retinitis--foscarnet and ganciclovir. The CMV retinitis retreatment trial. ( Jabs, DA, 1996)
"The use of foscarnet and ganciclovir as a combination treatment for cytomegalovirus retinitis is increasing because of limitations associated with single agent therapy."9.08Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis. ( Aweeka, FT; Emrick, L; Gambertoglio, JG; Jacobson, MA; Jayewardene, A; Kramer, F; Lizak, P; Polsky, B; Tong, W; van der Horst, C, 1995)
" The Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial is a multicenter, randomized, controlled, unmasked, clinical trial that compared ganciclovir and foscarnet as treatments for CMV retinitis in patients with AIDS."9.07Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. 4. Visual outcomes. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. ( , 1994)
"The pharmacodynamic relationship between a range of foscarnet exposure measurements obtained from studying nine patients receiving ongoing maintenance therapy for cytomegalovirus retinitis and a range of efficacy values (days to retinitis progression) obtained by independent examination of serial retinal photographs from the same nine patients was analyzed."9.07Pharmacodynamic relationship of pharmacokinetic parameters of maintenance doses of foscarnet and clinical outcome of cytomegalovirus retinitis. ( Causey, D; Davis, R; Feinberg, J; Heinemann, MH; Jacobson, MA; Kuppermann, BD; Lizak, P; O'Donnell, JJ; Polsky, B; Tong, W, 1994)
"The efficacy and tolerance of high dose intravitreal foscarnet for cytomegalovirus retinitis in patients with AIDS was studied."9.07High dose intravitreal foscarnet in the treatment of cytomegalovirus retinitis in AIDS. ( Cano, J; Chipont, E; Diaz-Llopis, M; España, E; Menezo, JL; Muñoz, G; Navea, A; Romero, FJ, 1994)
"The aim of this study was to investigate peripheral blood polymorphonuclear leukocytes and, whenever possible, aqueous humor from 65 AIDS patients with ophthalmoscopically diagnosed human cytomegalovirus (HCMV) retinitis to determine (i) whether patients consistently carry viral DNA and (ii) to what extent foscarnet induction treatment decreases viral DNA levels."9.07Effect of foscarnet induction treatment on quantitation of human cytomegalovirus (HCMV) DNA in peripheral blood polymorphonuclear leukocytes and aqueous humor of AIDS patients with HCMV retinitis. The Italian Foscarnet Study Group. ( Baldanti, F; Furione, M; Gerna, G; Percivalle, E; Revello, MG; Sarasini, A; Zella, D; Zipeto, D, 1994)
"A patient with systemic cytomegalovirus (CMV), including chorioretinitis, received localized and systemic ganciclovir, systemic cidofovir analog, and localized foscarnet."7.78Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma. ( Chavala, S; Miller, MB; Moss, HB; Say, E, 2012)
"The purpose of this report was to develop solvent-free biodegradable scleral plugs for simultaneous ganciclovir and foscarnet delivery for cytomegalovirus retinitis treatment."7.76Sustained release of ganciclovir and foscarnet from biodegradable scleral plugs for the treatment of cytomegalovirus retinitis. ( Chiou, SH; Liu, SJ; Peng, YJ; Wen, CW, 2010)
"To describe the chronic use of high doses of intravitreal ganciclovir, in combination with foscarnet, for the treatment of cytomegalovirus retinitis."7.71High-dose intravitreal ganciclovir and foscarnet for cytomegalovirus retinitis. ( Chan, CC; Robinson, MR; Roy, CE; Velez, G; Whitcup, SM, 2001)
"We report three pediatric patients with ganciclovir-resistant cytomegalovirus (CMV) retinitis who were successfully treated with foscarnet."7.71Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis after stem cell transplantation: effective monitoring of CMV infection by quantitative analysis of CMV mRNA. ( Amo, K; Aono, T; Hara, J; Kim, JY; Matsuda, Y; Miyagawa, H; Ohta, H; Okada, S; Sashihara, J; Sawada, A; Tanaka-Taya, K; Tano, Y; Tokimasa, S; Yamamoto, S; Yamanishi, K, 2001)
"Three human immunodeficiency virus-infected subjects with progressive cytomegalovirus (CMV) retinitis despite prolonged antiviral therapy had buffy coat CMV isolates that were resistant to both ganciclovir and foscarnet."7.70Mutation in region III of the DNA polymerase gene conferring foscarnet resistance in cytomegalovirus isolates from 3 subjects receiving prolonged antiviral therapy. ( Chou, S; Drew, WL; Gordon, SM; LaVoy, AG; Marousek, G; Miner, RC; Parenti, DM; Ross, JG, 1998)
"Viral resistance to foscarnet or ganciclovir may explain refractory cytomegalovirus retinitis in some patients."7.69Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir. ( Apuzzo, L; Charache, P; Dunn, JP; Forman, MS; Jabs, DA; MacCumber, MW, 1995)
" Administration of foscarnet during two years, recommended as suppressive therapy for a previous cytomegalovirus retinitis, might have caused a sustained reduction in plasma HIV-RNA, contributing to her long-term survival."7.69[Long term survival in an HIV-immunosuppressed patient treated with foscarnet]. ( Bravo, R; González-Lahoz, J; Mas, A; Moreno, V; Soriano, V, 1996)
"These results suggest that while ganciclovir therapy may clinically stabilize CMV retinitis in patients with AIDS, it does not appear to prevent the development of, or be effective in the treatment of, CMV encephalitis."7.69The development of cytomegalovirus encephalitis in AIDS patients receiving ganciclovir. ( Berman, SM; Kim, RC, 1994)
"We treated seven patients (nine eyes) who had cytomegalovirus retinitis with daily intravenous ganciclovir plus foscarnet."7.69Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis. ( Murphy, R; Naughton, K; Weinberg, DV, 1994)
"To determine the efficacy of combined ganciclovir and foscarnet intravitreal injections in controlling clinically resistant cytomegalovirus retinitis in a 37-year-old man with the acquired immunodeficiency syndrome who refused systemic therapy."7.69Treatment of clinically resistant cytomegalovirus retinitis with combined intravitreal injections of ganciclovir and foscarnet. ( Desatnik, HR; Foster, RE; Lowder, CY, 1996)
"This study evaluated intravitreous and plasma ganciclovir and foscarnet concentrations after intravenous administration in AIDS patients with cytomegalovirus (CMV) retinitis and retinal detachment."7.69Intravitreous and plasma concentrations of ganciclovir and foscarnet after intravenous therapy in patients with AIDS and cytomegalovirus retinitis. ( Arevalo, JF; Bergeron-Lynn, G; Capparelli, EV; Connor, JD; Freeman, WR; Gambertoglio, J; Garcia, RF; Gonzalez, C; Kirsch, LS; Quiceno, JI, 1995)
"We report on a 28-year-old AIDS patient who developed a rapidly progressive glomerulonephritis while being treated with foscarnet for cytomegalovirus retinitis."7.69Crescentic glomerulonephritis and crystals within glomerular capillaries in an AIDS patient treated with foscarnet. ( Cahen, R; Cotte, L; Dijoud, F; François, B; Patricot, LM; Trepo, C; Trolliet, P, 1995)
"Foscarnet is a pyrophosphate analogue that possesses substantial activity against human cytomegalovirus (HCMV) in patients with CMV retinitis."7.69In vitro anti-human cytomegalovirus activity of liposome-encapsulated foscarnet. ( Cinatl, J; Doerr, HW; Gümbel, HO; Ohrloff, C; Rabenau, H; Rückert, DG, 1994)
"To assess the clinical response and patient tolerance to daily infusions of both ganciclovir sodium and foscarnet sodium for the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome."7.68Combination ganciclovir and foscarnet in the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. ( Flores-Aguilar, M; Freeman, WR; Kuppermann, BD; Quiceno, JI; Rickman, LS, 1993)
" In both regimens the elimination half-life of foscarnet was 2-3 h."6.68Comparison of pharmacokinetics and dynamics of two dosage regimens of foscarnet in AIDS patients with Cytomegalovirus retinitis. ( Carosi, G; Castelli, F; Hedman, A; Suter, F; Tomasoni, L; Trespi, G; Zeroli, C, 1997)
"Patients were randomized to one of three therapeutic regimens: induction with foscarnet sodium at 90 mg/kg intravenously every 12 hours for 2 weeks, followed by maintenance at a dosage of 120 mg/kg per day (foscarnet group); induction with ganciclovir sodium at 5 mg/kg intravenously every 12 hours for 2 weeks followed by maintenance at 10 mg/kg per day (ganciclovir group); or continuation of previous maintenance therapy plus induction with the other drug (either ganciclovir or foscarnet) for 2 weeks followed by maintenance therapy with both drugs, ganciclovir sodium at 5 mg/kg per day and foscarnet sodium at 90 mg/kg per day (combination therapy group)."6.68Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The Cytomegalovirus Retreatment Trial. The Studies of Ocular Complications of AIDS Research Group in Collaboration ( , 1996)
"Retinal detachment was not associated with the type of anticytomegalovirus therapy (intravenous foscarnet or ganciclovir) to which the patient was assigned."6.68Rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis: the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS (SOCA) Research Group in Collaboration with the AIDS Clinical Trials Group ( , 1997)
" The dosing regimen for induction with the combined therapy was foscarnet (60 mg/kg every 8 hours) and ganciclovir (5 mg/kg daily for 3 weeks)."5.29Combined intravenous ganciclovir and foscarnet for children with recurrent cytomegalovirus retinitis. ( Lewis, LL; Mueller, BU; Nussenblatt, RB; Pizzo, PA; Walton, RC; Whitcup, SM, 1995)
"A 41-year-old man with acquired immunodeficiency syndrome (AIDS) developed cytomegalovirus (CMV) retinitis."5.29[Foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome]. ( Fujino, Y; Kimura, S; Mochizuki, M; Mouri, H; Nagata, Y; Oka, S; Ono, A; Shimada, K, 1994)
"Cytomegalovirus retinitis is the leading cause of blindness in adults and children with acquired immunodeficiency syndrome (AIDS)."5.29Combined ganciclovir and foscarnet in pediatric cytomegalovirus retinitis. ( Epps, CH; Rana, SN; Sanders, RJ; Sastry, SM; Walton, RC, 1996)
"The clinical significance of cytomegalovirus (CMV) foscarnet resistance was studied in patients with acquired immunodeficiency syndrome and CMV retinitis."5.10Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. ( Chou, S; Crumpacker, C; Forman, MS; Jabs, DA; Lurain, NS; Martin, BK; Weinberg, A, 2003)
"Two hundred thirty-four patients with the acquired immunodeficiency syndrome and previously untreated cytomegalovirus retinitis at 11 university centers were randomly assigned to receive intravenously either foscarnet (n = 107) or ganciclovir (n = 127)."5.08Morbidity and toxic effects associated with ganciclovir or foscarnet therapy in a randomized cytomegalovirus retinitis trial. Studies of ocular complications of AIDS Research Group, in collaboration with the AIDS Clinical Trials Group. ( , 1995)
"The Cytomegalovirus Retinitis Retreatment Trial was a multicenter clinical trial designed to evaluate three treatments for the treatment of relapsed CMV retinitis; (1) foscarnet; (2) 'high-dose' ganciclovir, and (3) combination foscarnet and ganciclovir."5.08Design of clinical trials for drug combinations: cytomegalovirus retinitis--foscarnet and ganciclovir. The CMV retinitis retreatment trial. ( Jabs, DA, 1996)
"Twenty-six subjects enrolled in a randomized trial that compared foscarnet and ganciclovir for the treatment of cytomegalovirus retinitis."5.08Measuring visual function and quality of life in patients with cytomegalovirus retinitis. Development of a questionnaire. Studies of Ocular Complication of AIDS Research Group. ( Coleson, LC; Holbrook, J; Jabs, DA; Wu, AW, 1996)
"The use of foscarnet and ganciclovir as a combination treatment for cytomegalovirus retinitis is increasing because of limitations associated with single agent therapy."5.08Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis. ( Aweeka, FT; Emrick, L; Gambertoglio, JG; Jacobson, MA; Jayewardene, A; Kramer, F; Lizak, P; Polsky, B; Tong, W; van der Horst, C, 1995)
"The aim of this study was to investigate peripheral blood polymorphonuclear leukocytes and, whenever possible, aqueous humor from 65 AIDS patients with ophthalmoscopically diagnosed human cytomegalovirus (HCMV) retinitis to determine (i) whether patients consistently carry viral DNA and (ii) to what extent foscarnet induction treatment decreases viral DNA levels."5.07Effect of foscarnet induction treatment on quantitation of human cytomegalovirus (HCMV) DNA in peripheral blood polymorphonuclear leukocytes and aqueous humor of AIDS patients with HCMV retinitis. The Italian Foscarnet Study Group. ( Baldanti, F; Furione, M; Gerna, G; Percivalle, E; Revello, MG; Sarasini, A; Zella, D; Zipeto, D, 1994)
"The efficacy and tolerance of high dose intravitreal foscarnet for cytomegalovirus retinitis in patients with AIDS was studied."5.07High dose intravitreal foscarnet in the treatment of cytomegalovirus retinitis in AIDS. ( Cano, J; Chipont, E; Diaz-Llopis, M; España, E; Menezo, JL; Muñoz, G; Navea, A; Romero, FJ, 1994)
"The pharmacodynamic relationship between a range of foscarnet exposure measurements obtained from studying nine patients receiving ongoing maintenance therapy for cytomegalovirus retinitis and a range of efficacy values (days to retinitis progression) obtained by independent examination of serial retinal photographs from the same nine patients was analyzed."5.07Pharmacodynamic relationship of pharmacokinetic parameters of maintenance doses of foscarnet and clinical outcome of cytomegalovirus retinitis. ( Causey, D; Davis, R; Feinberg, J; Heinemann, MH; Jacobson, MA; Kuppermann, BD; Lizak, P; O'Donnell, JJ; Polsky, B; Tong, W, 1994)
" The Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial is a multicenter, randomized, controlled, unmasked, clinical trial that compared ganciclovir and foscarnet as treatments for CMV retinitis in patients with AIDS."5.07Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. 4. Visual outcomes. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. ( , 1994)
"A patient with systemic cytomegalovirus (CMV), including chorioretinitis, received localized and systemic ganciclovir, systemic cidofovir analog, and localized foscarnet."3.78Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma. ( Chavala, S; Miller, MB; Moss, HB; Say, E, 2012)
"The purpose of this report was to develop solvent-free biodegradable scleral plugs for simultaneous ganciclovir and foscarnet delivery for cytomegalovirus retinitis treatment."3.76Sustained release of ganciclovir and foscarnet from biodegradable scleral plugs for the treatment of cytomegalovirus retinitis. ( Chiou, SH; Liu, SJ; Peng, YJ; Wen, CW, 2010)
"We report three pediatric patients with ganciclovir-resistant cytomegalovirus (CMV) retinitis who were successfully treated with foscarnet."3.71Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis after stem cell transplantation: effective monitoring of CMV infection by quantitative analysis of CMV mRNA. ( Amo, K; Aono, T; Hara, J; Kim, JY; Matsuda, Y; Miyagawa, H; Ohta, H; Okada, S; Sashihara, J; Sawada, A; Tanaka-Taya, K; Tano, Y; Tokimasa, S; Yamamoto, S; Yamanishi, K, 2001)
"A 7-year-old HIV-infected male with frosted branch angiitis was refractory to induction doses of intravenous ganciclovir and foscarnet over a 2-month period."3.71Frosted branch angiitis in a child with HIV infection. ( Fine, HF; Murante, BL; Nussenblatt, RB; Robinson, MR; Smith, JA, 2001)
"To describe the chronic use of high doses of intravitreal ganciclovir, in combination with foscarnet, for the treatment of cytomegalovirus retinitis."3.71High-dose intravitreal ganciclovir and foscarnet for cytomegalovirus retinitis. ( Chan, CC; Robinson, MR; Roy, CE; Velez, G; Whitcup, SM, 2001)
"Three acquired immune deficiency syndrome patients given foscarnet to treat cytomegalovirus retinitis developed renal failure with crystal deposits within the renal glomeruli."3.70Identification of crystals in kidneys of AIDS patients treated with foscarnet. ( Beaufils, H; Daudon, M; Jouanneau, C; Katlama, C; Lacour, B; Maurice-Estepa, L; Sazdovitch, V, 1998)
"To determine intraocular toxicity and efficacy of the lipid prodrug of foscarnet, 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA), as a long-acting, nontoxic intravitreous injectable drug delivery system for cytomegalovirus (CMV) retinitis."3.70Intravitreal toxicology in rabbits of two preparations of 1-O-octadecyl-sn-glycerol-3-phosphonoformate, a sustained-delivery anti-CMV drug. ( Avila, CP; Bergeron-Lynn, G; Cheng, L; Freeman, WR; Gardner, MF; Hostetler, KY; Keefe, KS; Wiley, CA, 1999)
"Three human immunodeficiency virus-infected subjects with progressive cytomegalovirus (CMV) retinitis despite prolonged antiviral therapy had buffy coat CMV isolates that were resistant to both ganciclovir and foscarnet."3.70Mutation in region III of the DNA polymerase gene conferring foscarnet resistance in cytomegalovirus isolates from 3 subjects receiving prolonged antiviral therapy. ( Chou, S; Drew, WL; Gordon, SM; LaVoy, AG; Marousek, G; Miner, RC; Parenti, DM; Ross, JG, 1998)
"A patient with AIDS and cytomegalovirus (CMV) retinitis received ganciclovir and foscarnet for 20 and 5 months, respectively, with evidence of periodic disease progression."3.70A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance. ( Chou, S; Drew, WL; Miner, RC, 2000)
"This study evaluated intravitreous and plasma ganciclovir and foscarnet concentrations after intravenous administration in AIDS patients with cytomegalovirus (CMV) retinitis and retinal detachment."3.69Intravitreous and plasma concentrations of ganciclovir and foscarnet after intravenous therapy in patients with AIDS and cytomegalovirus retinitis. ( Arevalo, JF; Bergeron-Lynn, G; Capparelli, EV; Connor, JD; Freeman, WR; Gambertoglio, J; Garcia, RF; Gonzalez, C; Kirsch, LS; Quiceno, JI, 1995)
"These results suggest that while ganciclovir therapy may clinically stabilize CMV retinitis in patients with AIDS, it does not appear to prevent the development of, or be effective in the treatment of, CMV encephalitis."3.69The development of cytomegalovirus encephalitis in AIDS patients receiving ganciclovir. ( Berman, SM; Kim, RC, 1994)
"To determine the efficacy of combined ganciclovir and foscarnet intravitreal injections in controlling clinically resistant cytomegalovirus retinitis in a 37-year-old man with the acquired immunodeficiency syndrome who refused systemic therapy."3.69Treatment of clinically resistant cytomegalovirus retinitis with combined intravitreal injections of ganciclovir and foscarnet. ( Desatnik, HR; Foster, RE; Lowder, CY, 1996)
"To determine the prevalence of cytomegalovirus (CMV) isolates resistant to ganciclovir sodium or foscarnet sodium at the time of diagnosis of CMV retinitis, prior to the initiation of therapy."3.69Cytomegalovirus retinitis and viral resistance. Prevalence of resistance at diagnosis, 1994. Cytomegalovirus Retinitis and Viral Resistance Study Group. ( Bressler, N; Charache, P; Dunn, JP; Enger, C; Forman, M; Jabs, DA, 1996)
"Foscarnet is a pyrophosphate analogue that possesses substantial activity against human cytomegalovirus (HCMV) in patients with CMV retinitis."3.69In vitro anti-human cytomegalovirus activity of liposome-encapsulated foscarnet. ( Cinatl, J; Doerr, HW; Gümbel, HO; Ohrloff, C; Rabenau, H; Rückert, DG, 1994)
" We attempted to detect cytomegalovirus DNA in 19 vitreous samples from patients with the acquired immunodeficiency syndrome (AIDS) who had untreated cytomegalovirus retinitis and in 40 vitreous samples from patients with AIDS who had been treated with systemic ganciclovir or foscarnet, or both."3.69A sensitive and specific polymerase chain reaction-based assay for the diagnosis of cytomegalovirus retinitis. ( Ai, E; Irvine, AR; Kuppermann, BD; Luckie, AP; Margolis, TP; McCann, JD; Schwartz, DM; Wong, MG, 1995)
"We treated seven patients (nine eyes) who had cytomegalovirus retinitis with daily intravenous ganciclovir plus foscarnet."3.69Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis. ( Murphy, R; Naughton, K; Weinberg, DV, 1994)
" Administration of foscarnet during two years, recommended as suppressive therapy for a previous cytomegalovirus retinitis, might have caused a sustained reduction in plasma HIV-RNA, contributing to her long-term survival."3.69[Long term survival in an HIV-immunosuppressed patient treated with foscarnet]. ( Bravo, R; González-Lahoz, J; Mas, A; Moreno, V; Soriano, V, 1996)
"We report on a 28-year-old AIDS patient who developed a rapidly progressive glomerulonephritis while being treated with foscarnet for cytomegalovirus retinitis."3.69Crescentic glomerulonephritis and crystals within glomerular capillaries in an AIDS patient treated with foscarnet. ( Cahen, R; Cotte, L; Dijoud, F; François, B; Patricot, LM; Trepo, C; Trolliet, P, 1995)
"Viral resistance to foscarnet or ganciclovir may explain refractory cytomegalovirus retinitis in some patients."3.69Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir. ( Apuzzo, L; Charache, P; Dunn, JP; Forman, MS; Jabs, DA; MacCumber, MW, 1995)
"Advances in ganciclovir and foscarnet therapies for treating cytomegalovirus retinitis, including ocular implants and injections, alternating use of foscarnet and ganciclovir, oral ganciclovir use, cidofovir treatment, and injecting either ganciclovir or foscarnet directly into affected eyes, are discussed."3.69Advances in treatment for cytomegalovirus retinitis. ( Bowers, M, 1995)
"Cytomegalovirus (CMV) retinitis, a sight-threatening infection common in AIDS patients, can be treated systemically with intravenous ganciclovir, intravenous foscarnet, or oral ganciclovir."3.69Intraocular therapy for cytomegalovirus retinitis. ( Palestine, AG, 1996)
"Foscavir (foscarnet sodium) has been approved by the Food and Drug Administration (FDA) for use in combination with Cytovene (intravenous ganciclovir) for the treatment of recurrent AIDS-related cytomegalovirus retinitis that has been treated previously with either drug alone."3.69Foscavir receives new indication. ( , 1997)
"To assess the clinical response and patient tolerance to daily infusions of both ganciclovir sodium and foscarnet sodium for the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome."3.68Combination ganciclovir and foscarnet in the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. ( Flores-Aguilar, M; Freeman, WR; Kuppermann, BD; Quiceno, JI; Rickman, LS, 1993)
"ACTG 266 was designed as a randomized study to evaluate two doses of the human monoclonal antibody directed against CMV gH (MSL-109) versus placebo, each in combination with standard antiviral therapy for the treatment of newly diagnosed Cytomegalovirus (CMV) retinitis in AIDS patients."2.71A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus re ( Alston, B; Asmuth, DM; Aweeka, F; Borucki, MJ; Caliendo, A; Gnann, J; Hirsch, MS; Hubbard, L; Nadler, PI; Nevin, TT; Nokta, M; Owens, S; Pollard, RB; Sattler, F; Spritzler, J; Waterman, K, 2004)
"Patients were randomized to one of three therapeutic regimens: induction with foscarnet sodium at 90 mg/kg intravenously every 12 hours for 2 weeks, followed by maintenance at a dosage of 120 mg/kg per day (foscarnet group); induction with ganciclovir sodium at 5 mg/kg intravenously every 12 hours for 2 weeks followed by maintenance at 10 mg/kg per day (ganciclovir group); or continuation of previous maintenance therapy plus induction with the other drug (either ganciclovir or foscarnet) for 2 weeks followed by maintenance therapy with both drugs, ganciclovir sodium at 5 mg/kg per day and foscarnet sodium at 90 mg/kg per day (combination therapy group)."2.68Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The Cytomegalovirus Retreatment Trial. The Studies of Ocular Complications of AIDS Research Group in Collaboration ( , 1996)
" In both regimens the elimination half-life of foscarnet was 2-3 h."2.68Comparison of pharmacokinetics and dynamics of two dosage regimens of foscarnet in AIDS patients with Cytomegalovirus retinitis. ( Carosi, G; Castelli, F; Hedman, A; Suter, F; Tomasoni, L; Trespi, G; Zeroli, C, 1997)
" However, patients with positive baseline CMV blood cultures had a significantly more shallow dose-response curve."2.68Relationship between foscarnet exposure, baseline cytomegalovirus (CMV) blood culture and the time to progression of CMV retinitis in HIV-positive patients. ( Aweeka, F; Drusano, GL; Eaton, C; Gambertoglio, J; Jacobson, M; Lane, HC; Martin-Munley, S; Polis, M, 1996)
"Retinal detachment was not associated with the type of anticytomegalovirus therapy (intravenous foscarnet or ganciclovir) to which the patient was assigned."2.68Rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis: the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS (SOCA) Research Group in Collaboration with the AIDS Clinical Trials Group ( , 1997)
"However, it may develop in patients with acute lymphoblastic leukemia (ALL) who have not undergone hematopoietic cell transplantation."2.53Cytomegalovirus Retinitis in Three Pediatric Cases with Acute Lymphoblastic Leukemia: Case Series and Review of the Literature. ( Akkoç, G; Atıcı, S; Bakır, M; Çeliker, H; Demir, SÖ; Kadayifci, EK; Karaaslan, A; Kazokoğlu, H; Koç, A; Şenay, E; Soysal, A; Yakut, N, 2016)
" Valganciclovir, a prodrug of ganciclovir, offers excellent oral bioavailability and is the closest to approval of all the new anti-CMV drugs."2.41Therapeutic developments in cytomegalovirus retinitis. ( Hoffman, VF; Skiest, DJ, 2000)
"CMV-related retinal detachment is treated surgically."2.40Cytomegalovirus retinitis in patients with acquired immune deficiency syndrome. ( Au Eong, KG; Beatty, S; Charles, SJ, 1999)
" Other new methods involve liposomal systems to increase drug contact time, use of longer-acting drugs with less-frequent dosing requirements, and methods to improve quality of life by avoiding intravenous drug delivery."2.40Pharmacologic management of cytomegalovirus retinitis: review of current and future therapeutic modalities. ( Bright, DC, 1997)
"The median number of recurrences up to the observation of foveal-sparing retinitis was two (range one to eight), and five patients had active CMV retinitis despite treatment for at least two continuous months."2.39A foveal-sparing pattern of cytomegalovirus retinitis in the acquired immunodeficiency syndrome. ( Ai, E; Luckie, AP, 1996)
"Foscarnet sodium is an antiviral drug for the treatment of CMV retinitis, currently in the form of twice-weekly intravitreal injection."1.46Foscarnet calcium microcrystals as the intravitreal drug depot. ( Cao, Q; Huang, Y; Sun, Y; Tao, Y, 2017)
"Bilateral recurrence of CMV retinitis occurred on day 89 of life, requiring a second course of intravitreal foscarnet injections and intravenous ganciclovir."1.40Intravitreal foscarnet for recurring CMV retinitis in a congenitally infected premature infant. ( Baumal, CR; Tawse, KL, 2014)
"The incidence of cytomegalovirus retinitis has decreased significantly since the advent of antiretroviral therapy."1.40Management of ganciclovir-resistant cytomegalovirus retinitis in HIV infection in the era of antiretroviral therapy. ( Acheson, RW; Adler, H; Brannigan, ET; De Gascun, CF; Duffy, M; Keegan, DJ; Lambert, JS; McSweeney, F, 2014)
"Cytomegalovirus retinitis is an opportunistic infection found in AIDS patients as well as in bone marrow and solid organ transplant recipients being treated with systemic immunosuppressive drugs."1.39A possible coincidence of cytomegalovirus retinitis and intraocular lymphoma in a patient with systemic non-Hodgkin's lymphoma. ( Brichová, M; Dvořák, J; Heissigerová, J; Kalvodová, B; Ríhová, E; Svozílková, P, 2013)
"Retinal detachment is the main complication."1.32[Acute retinal necrosis: clinical presentation, treatment, and prognosis in a series of 22 patients]. ( Laroche, L; Larricart, P; Metge, F; Monin, C; Morel, C; Roman, S; Scheer, S, 2004)
"An exacerbation of the myelitis, retinitis, encephalitis and colitis was observed and a cytomegalovirus infection diagnosed."1.31CMV complications in common variable immunodeficiency. ( Schmidt, RE; Werwitzke, S; Witte, T, 2000)
"In one eye, the cystoid macular edema was worsened by formation of a dense juxtafoveal epiretinal membrane."1.30Cystoid macular edema associated with cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. ( Cunningham, ET; Jones, MR; Schwartz, D; Silverstein, BE; Smith, JH; Sykes, SO, 1998)
"A mild recurrence developed in one eye when ganciclovir and foscarnet were both tapered to a single daily dose."1.30The progressive outer retinal necrosis syndrome: successful treatment with combination antiviral therapy. ( Ciulla, TA; Duker, JS; Morley, MG; Rutledge, BK, 1998)
"Retinal detachment was seen in 14 patients (relative frequency, 19."1.29Retinal detachment in patients with acquired immunodeficiency syndrome. ( Bogner, JR; Geier, SA; Goebel, FD; Klauss, V; Sadri, I; Schmidt-Kittler, H, 1994)
"CMV viremia was present in 4 patients."1.29Cytomegalovirus ventriculoencephalitis in AIDS patients. ( Fernandez-Viladrich, P; Ferrer, I; Gudiol, F; Perez, JL; Podzamczer, D; Reñe, R; Salazar, A; Santin, M, 1995)
"Sera obtained from AIDS patients with cytomegalovirus (CMV) retinitis before and after treatment with foscarnet, AIDS patients with human immunodeficiency virus (HIV) retinopathy, AIDS patients without retinal disease, and normal healthy controls with and without positive CMV serologies were assayed for the presence of antibodies against the 200-kDa outer, 160-kDa middle, and 68-kDa core subunits of the neurofilament triplet."1.29Antineurofilament and antiretinal antibodies in AIDS patients with cytomegalovirus retinitis. ( Cunningham-Rundles, S; Heinemann, MH; Klein, RF; Polsky, B; Rosberger, DF; Tshering, SL, 1994)
"Approximately one-third of all AIDS patients develop cytomegalovirus (CMV) retinitis."1.29Detecting CMV retinitis: know what to look for. Treatment is effective but not pleasant. ( , 1996)
" The dosing regimen for induction with the combined therapy was foscarnet (60 mg/kg every 8 hours) and ganciclovir (5 mg/kg daily for 3 weeks)."1.29Combined intravenous ganciclovir and foscarnet for children with recurrent cytomegalovirus retinitis. ( Lewis, LL; Mueller, BU; Nussenblatt, RB; Pizzo, PA; Walton, RC; Whitcup, SM, 1995)
"In persons with AIDS (PWAs), cytomegalovirus (CMV) infection can cause a broad spectrum of clinical manifestations."1.29Spectrum and treatment of cytomegalovirus disease in persons with AIDS. ( Spector, SA, 1996)
"A 41-year-old man with acquired immunodeficiency syndrome (AIDS) developed cytomegalovirus (CMV) retinitis."1.29[Foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome]. ( Fujino, Y; Kimura, S; Mochizuki, M; Mouri, H; Nagata, Y; Oka, S; Ono, A; Shimada, K, 1994)
"Cytomegalovirus retinitis is the leading cause of blindness in adults and children with acquired immunodeficiency syndrome (AIDS)."1.29Combined ganciclovir and foscarnet in pediatric cytomegalovirus retinitis. ( Epps, CH; Rana, SN; Sanders, RJ; Sastry, SM; Walton, RC, 1996)
"A patient with Hodgkin's disease presented with an atypical retinitis, vasculitis, and a serous macular detachment."1.29Cytomegalovirus retinitis associated with Hodgkin's disease. ( Jaffe, GJ; Nasir, MA, 1996)

Research

Studies (191)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's142 (74.35)18.2507
2000's27 (14.14)29.6817
2010's20 (10.47)24.3611
2020's2 (1.05)2.80

Authors

AuthorsStudies
Lee, HJ1
Woo, SJ1
Hafidi, M1
Janin-Manificat, H1
Denis, P1
Charleux, B1
Rabilloud, M1
Boibieux, A1
Burillon, C1
Kodjikian, L1
Frobert, E1
Fu, L1
Santhanakrishnan, K1
Al-Aloul, M1
Jones, NP1
Steeples, LR1
Sun, Y1
Tao, Y1
Cao, Q1
Huang, Y1
Rothman, AL1
Walter, SD1
Gupta, S1
Vemulakonda, GA1
Suhler, EB1
Yeh, S3
Albini, TA2
Mandelcorn, E1
Flaxel, CJ2
Schneider, EW1
Elner, SG1
van Kuijk, FJ1
Goldberg, N1
Lieberman, RM2
Eliott, D1
Johnson, MW1
Adler, H1
De Gascun, CF1
McSweeney, F1
Acheson, RW1
Brannigan, ET1
Duffy, M1
Keegan, DJ1
Lambert, JS1
Tawse, KL1
Baumal, CR1
Vishnevskia-Dai, V1
Shapira, Y1
Rahav, G1
Shimoni, A1
Somech, R1
Moisseiev, J1
Churgin, D1
Relhan, N1
Davis, JL1
Timperley, A1
Taha, H1
Das, S1
Demir, SÖ1
Çeliker, H1
Karaaslan, A1
Kadayifci, EK1
Akkoç, G1
Atıcı, S1
Yakut, N1
Şenay, E1
Kazokoğlu, H1
Koç, A1
Bakır, M1
Soysal, A1
Boss, JD1
Rosenberg, K1
Shah, R1
Oshima, K1
Kanda, Y1
Kako, S1
Asano-Mori, Y1
Watanabe, T1
Motokura, T1
Chiba, S1
Shiraki, K1
Kurokawa, M1
Rothova, A1
de Weerdt, O1
Jabs, DA12
Martin, BK3
Forman, MS3
Peng, YJ1
Wen, CW1
Chiou, SH1
Liu, SJ1
Forooghian, F2
Faia, LJ2
Weichel, ED2
Wong, WT1
Sen, HN2
Chan-Kai, BT1
Witherspoon, SR1
Lauer, AK2
Chew, EY1
Nussenblatt, RB4
Fahle, G1
Stout, JT1
Moss, HB1
Chavala, S1
Say, E1
Miller, MB1
Kobayashi, R1
Takanashi, K1
Suzuki, D1
Nasu, T1
Uetake, K1
Matsumoto, Y1
Martínez-Castillo, S1
Marín-Lambíes, C1
Gallego-Pinazo, R1
Arévalo, JF2
Díaz-Llopis, M2
Svozílková, P1
Heissigerová, J1
Brichová, M1
Kalvodová, B1
Dvořák, J1
Ríhová, E1
Larsson, K1
Lönnqvist, B1
Ringdén, O1
Hedquist, B1
Ljungman, P1
Holbrook, JT2
Weinberg, DV2
Lewis, RA1
Davis, MD2
Friedberg, D1
Weinberg, A1
Chou, S3
Lurain, NS1
Crumpacker, C1
Rapp, P1
Pilon, F1
Chiambaretta, F1
Ménérath, JM1
Jacomet, C1
Morel, C1
Metge, F1
Roman, S1
Scheer, S1
Larricart, P1
Monin, C1
Laroche, L1
Borucki, MJ1
Spritzler, J1
Asmuth, DM1
Gnann, J1
Hirsch, MS1
Nokta, M1
Aweeka, F2
Nadler, PI1
Sattler, F1
Alston, B1
Nevin, TT1
Owens, S2
Waterman, K1
Hubbard, L2
Caliendo, A1
Pollard, RB2
Demols, P1
Claes, CA1
Farber, CM1
Rasquin, F1
Nakamoto, BK1
Dorotheo, EU1
Biousse, V1
Tang, RA1
Schiffman, JS1
Newman, NJ1
Ausayakhun, S1
Watananikorn, S1
Ngamtiphakorn, S1
Prasitsilp, J1
Ufret-Vincenty, RL1
Singh, RP1
Lowder, CY3
Kaiser, PK1
Eid, AJ1
Bakri, SJ1
Kijpittayarit, S1
Razonable, RR1
Luckie, AP3
Fitzgerald, E1
Goldman, HM1
Miller, WG1
Purcell, SM1
Gonzalez, C1
Capparelli, EV1
Kirsch, LS1
Garcia, RF1
Quiceno, JI3
Connor, JD1
Gambertoglio, J2
Bergeron-Lynn, G2
Freeman, WR7
Trolliet, P1
Dijoud, F1
Cotte, L1
Cahen, R1
François, B1
Trepo, C1
Patricot, LM1
McCann, JD1
Margolis, TP1
Wong, MG1
Kuppermann, BD4
Schwartz, DM1
Irvine, AR2
Ai, E2
Holida, MD1
Trigg, ME1
Rumelhart, SL1
Lee, NF1
Kook, H1
Peters, C1
Salazar, A1
Podzamczer, D1
Reñe, R1
Santin, M1
Perez, JL1
Ferrer, I1
Fernandez-Viladrich, P1
Gudiol, F1
Engstrom, RE1
Holland, GN3
Thimons, JJ1
Aweeka, FT1
Gambertoglio, JG1
Kramer, F1
van der Horst, C1
Polsky, B4
Jayewardene, A1
Lizak, P2
Emrick, L1
Tong, W2
Jacobson, MA8
Polis, MA1
Masur, H1
Dunn, JP4
MacCumber, MW1
Charache, P2
Apuzzo, L1
Levinson, RD1
Balfour, HH1
Colucciello, M1
Moyle, G1
Gazzard, BG2
Albrecht, H1
Stellbrink, HJ1
Brewster, D1
Greten, H1
Wulfsohn, M1
Feinberg, JE1
Davis, R2
Power, M1
Causey, D2
Heath-Chiozzi, ME1
Murphy, RL1
Cheung, TW1
Nagata, Y1
Fujino, Y1
Ono, A1
Mochizuki, M1
Mouri, H1
Oka, S1
Kimura, S1
Shimada, K1
O'Donnell, JJ1
Heinemann, MH3
Feinberg, J1
Orellana, J1
Melton, RC1
España, E1
Muñoz, G1
Navea, A1
Chipont, E1
Cano, J1
Menezo, JL1
Romero, FJ1
Gerna, G2
Baldanti, F1
Sarasini, A1
Furione, M1
Percivalle, E1
Revello, MG1
Zipeto, D1
Zella, D1
Gümbel, HO1
Rückert, DG1
Cinatl, J2
Rabenau, H1
Doerr, HW1
Ohrloff, C1
Geier, SA2
Klauss, V1
Bogner, JR2
Schmidt-Kittler, H1
Sadri, I2
Goebel, FD2
Berman, SM1
Kim, RC1
Murphy, R1
Naughton, K1
Flores-Aguilar, M2
Rickman, LS1
Leport, C1
Puget, S1
Pepin, JM1
Levy, S1
Perronne, C1
Brun-Vezinet, F1
Vildé, JL1
Ricart Olmos, C1
López Aldeguer, J1
Marino Blanes Juliá, F1
Sinelni, E1
Roarty, JD1
Fisher, EJ1
Nussbaum, JJ1
Friedberg, DN3
Berry, C1
Behette, M1
Fullerton, SC1
Munguia, D1
Spaide, RF1
Young, LH2
Giezendanner, S1
Wirth, HP1
Zala, G1
Weber, R1
Flury, R1
Meyenberger, C1
Rosberger, DF1
Tshering, SL1
Klein, RF1
Cunningham-Rundles, S1
Jayaweera, D1
White, G1
Moreno, J1
Huengsberg, M1
Stevenson, M1
Navarro, JF2
Quereda, C4
Gallego, N1
Antela, A1
Mora, C1
Ortuno, J1
Moreno, A1
Desatnik, HR1
Foster, RE2
Yoshizumi, MO1
Roca, JA1
Lee, DA1
Lee, G1
Gomez, I1
Enger, C3
Forman, M3
Bressler, N1
Hoover, DR1
Peng, Y1
Saah, A1
Semba, R1
Detels, RR1
Rinaldo, CR1
Phair, JP1
Wu, AW1
Coleson, LC1
Holbrook, J1
Dodds, EM1
Avery, RK1
Prayson, RA1
López-Cortés, LF1
Pachón-Díaz, J1
Flaherty, JF1
Hardy, D1
Conn, J1
Colman, P1
Brown, G1
Street, A1
Bate, K1
Zaman, MM1
Burney, S1
Landman, D1
Quale, JM1
Patel, SS1
Rutzen, AR1
Marx, JL1
Thach, AB1
Chong, LP1
Rao, NA1
Nasir, MA1
Jaffe, GJ1
Drusano, GL1
Jacobson, M1
Polis, M1
Lane, HC1
Eaton, C1
Martin-Munley, S1
Sastry, SM1
Epps, CH1
Walton, RC2
Rana, SN1
Sanders, RJ1
Luelmo, J1
Sala, M1
Sasal, M1
Cervantes, M1
Soriano, V1
Mas, A1
Bravo, R1
Moreno, V1
González-Lahoz, J1
Segondy, M1
Montes, B1
Delmas, B1
Leclercq, C1
Janbon, F1
Reynes, J1
Carosi, G2
Castelli, F2
Lernestedt, JO1
Antoniazzi, E1
Breton, G1
Crémieux, AC1
Bright, DC1
Hardy, WD1
Whitcup, SM2
Mueller, BU1
Lewis, LL1
Pizzo, PA1
Mallolas, J1
Gatell, JM1
Gómez-Sirvent, JL1
Buira, E1
Zamora, L1
Alecrim-Andrade, J1
Adán, A1
Morales, M1
Miró, JM1
Lonća, M1
Guelar, A1
Soriano, E1
Moore, DA1
Nelson, MR1
Stalder, N1
Sudre, P1
Olmari, M1
Opravil, M1
Gabriel, V1
Sansonetti, A1
von Overbeck, J1
Herbort, CP1
Hirschel, B1
Mueller, AJ1
Hurwitz, S1
Chuang, EL2
Haidt, SJ1
Kaplan, HJ1
Tomasoni, L1
Zeroli, C1
Suter, F1
Trespi, G1
Hedman, A1
Speyrer, MP1
Katlama, C2
Okamoto, T1
Okada, M1
Mori, A1
Saheki, K1
Takatsuka, H1
Wada, H1
Tamura, A1
Fujimori, Y1
Takemoto, Y1
Kanamaru, A1
Kakishita, E1
Pérez-Blázquez, E1
Traspas, R1
Méndez Marín, I1
Montero, M1
Lalezari, JP2
Usui, N1
Usui, M1
Guembel, HO1
Hofmann, F1
van Even, G1
Makabe, R1
Smith, CL1
Pau, AK1
Silverstein, BE1
Smith, JH1
Sykes, SO1
Jones, MR1
Schwartz, D1
Cunningham, ET1
Tural, C1
Romeu, J1
Sirera, G1
Andreu, D1
Conejero, M1
Ruiz, S1
Jou, A1
Bonjoch, A1
Ruiz, L1
Arnó, A1
Clotet, B1
Ciulla, TA1
Rutledge, BK1
Morley, MG1
Duker, JS1
Schürmann, D1
Bergmann, F1
Grobusch, MP1
Behnsch, M1
Liekfeld, A1
Althaus, C2
Loeffler, KU1
Schimkat, M1
Hudde, T1
Sundmacher, R1
Park, SS1
Girard, B1
Font, RL1
Hauw, JJ1
Ries, E1
Mühlbauer, B1
Ruhswurm, I1
Krepler, K1
Derbolav, A1
Svolba, G1
Rieger, A1
Wedrich, A1
Marousek, G1
Parenti, DM1
Gordon, SM1
LaVoy, AG1
Ross, JG1
Miner, RC2
Drew, WL4
Maurice-Estepa, L1
Daudon, M1
Jouanneau, C1
Sazdovitch, V1
Lacour, B1
Beaufils, H1
Goldfarb, DS1
Coe, FL1
Garcia, CR1
Torriani, FJ1
Barba, R1
Gómez-Rodrigo, J1
Marco, J1
Espejo, M1
Mena, D1
Cherrington, JM1
Fuller, MD1
Lamy, PD1
Miner, R1
Nuessle, S1
Zeichner, SL1
Verbraak, FD1
van den Horn, GJ1
van der Meer, JT1
Paydafar, D1
ten Kate, FJ1
Wertheim-van Dillen, PM1
Kijlstra, A1
Cochereau, I1
Belayachi, N1
Diraison, C1
Matheron, S1
Bouyer, I1
Hoang-Xuan, T1
Saimot, AG1
Coulaud, JP1
Fuchs, AV1
Wolf, E1
Scheider, A1
Jäger, H1
Kampik, A1
Skiest, DJ2
Cheng, L1
Hostetler, KY1
Gardner, MF1
Avila, CP1
Keefe, KS1
Wiley, CA1
Rabkin, CS1
Testa, MA1
Huang, J1
Von Roenn, JH1
Walmsley, S1
Tseng, A1
Hoy, J1
Au Eong, KG1
Beatty, S1
Charles, SJ1
Wutoh, AK1
Hidalgo, J1
Rhee, W1
Bareta, J1
Steidl, S1
Labetoulle, M1
Goujard, C1
Frau, E1
Rogier, H1
Niessen, F1
Furlan, V1
Lantz, O1
Lecointe, D1
Delfraissy, JF1
Offret, H1
Hubbard, LD1
Gilpin, AK1
Meinert, C1
Reshef, DS1
Witte, T1
Werwitzke, S1
Schmidt, RE1
Best, J1
Kersten, A1
Theisen, A1
Gantke, B1
Hoffman, VF1
Crippa, F1
Corey, L1
Sale, G1
Boeckh, M1
Fine, HF1
Smith, JA1
Murante, BL1
Robinson, MR2
Velez, G1
Roy, CE1
Chan, CC1
Blanchet, KD1
Cheng, B1
Woodward, J1
Baker, R1
Bowers, M1
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Spector, SA1
Highleyman, L1
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Veenstra, DL1
Ramsey, SD1
Steger, PJ1
Malinverni, R1
Pleil, AM1
Williamson, T1
Ohta, H1
Matsuda, Y1
Tokimasa, S1
Sawada, A1
Kim, JY1
Sashihara, J1
Amo, K1
Miyagawa, H1
Tanaka-Taya, K1
Yamamoto, S1
Tano, Y1
Aono, T1
Yamanishi, K1
Okada, S1
Hara, J1
Seo, SK1
Regan, A1
Cihlar, T1
Lin, DC1
Boulad, F1
George, D1
Prasad, VK1
Kiehn, TE1
Assi, AC1
Lightman, S1
Williams, IG1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component[NCT00000665]240 participants InterventionalCompleted
A Phase II, Double-Masked, Randomized, Placebo-Controlled Evaluation of Standard Therapy vs. Standard Therapy Combined With Human Monoclonal Anti-Cytomegalovirus Antibody (MSL 109) in the Therapy of AIDS Patients With Cytomegalovirus (CMV) Retinitis[NCT00001061]Phase 2167 participants InterventionalCompleted
Foscarnet-Ganciclovir CMV Retinitis Trial[NCT00000136]Phase 3234 participants (Actual)Interventional1990-03-31Completed
A Phase I Open-Labeled Study of Long Term Combined or Alternating Foscarnet/Ganciclovir Maintenance Therapy for AIDS Patients With CMV Retinitis After Ganciclovir Induction Therapy[NCT00000970]Phase 130 participants InterventionalCompleted
A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure[NCT00000691]Phase 2156 participants InterventionalCompleted
Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome[NCT00000726]Phase 153 participants InterventionalCompleted
Cytomegalovirus Retinitis Retreatment Trial[NCT00000134]Phase 3279 participants (Actual)Interventional1992-12-31Completed
CMV Retinitis Retreatment Trial[NCT00000766]Phase 2300 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mortality

(NCT00000136)
Timeframe: All patients enrolled will be followed until a common study closing date, which was chosen to provide a minimum of 1 year of follow-up for all patients enrolled in the trial.

Interventionparticipants (Number)
Foscarnet107
Ganciclovir127

Morbidity

To determine the best therapeutic regimen, using currently approved drugs, for treatment of relapsed cytomegalovirus (CMV) retinitis. (NCT00000134)
Timeframe: Patients will be seen at baseline, monthly for six months, and then every three months until death or termination of the trial

Interventionparticipants (Number)
Intravenous Foscarnet88
Intravenous Ganciclovir93
Combination Therapy93

Reviews

32 reviews available for foscarnet and Cytomegaloviral Retinitis

ArticleYear
Management of Ganciclovir Resistant Cytomegalovirus Retinitis in a Solid Organ Transplant Recipient: A Review of Current Evidence and Treatment Approaches.
    Ocular immunology and inflammation, 2020, Oct-02, Volume: 28, Issue:7

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans;

2020
Cytomegalovirus Retinitis in Three Pediatric Cases with Acute Lymphoblastic Leukemia: Case Series and Review of the Literature.
    Japanese journal of infectious diseases, 2016, Nov-22, Volume: 69, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Antiviral Agents; Child; Child, Presc

2016
Progressive outer retinal necrosis presenting with isolated optic neuropathy.
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infection

2004
Cytomegalovirus retinitis in patients with AIDS: current status.
    The Medical journal of Australia, 1995, Nov-06, Volume: 163, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Ganci

1995
Local therapy for cytomegalovirus retinopathy.
    American journal of ophthalmology, 1995, Volume: 120, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents, Local; Cytomegalovirus Retinitis; Dela

1995
CMV retinitis treatment.
    Optometry and vision science : official publication of the American Academy of Optometry, 1995, Volume: 72, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Humans

1995
Promising new treatments for cytomegalovirus retinitis.
    JAMA, 1995, May-10, Volume: 273, Issue:18

    Topics: AIDS-Related Opportunistic Infections; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants

1995
Current management of cytomegalovirus disease in patients with AIDS.
    AIDS research and human retroviruses, 1994, Volume: 10, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Therapy, Combination; Foscarn

1994
Cytomegalovirus retinitis in persons with AIDS. Selecting therapy for a sight-threatening disease.
    Postgraduate medicine, 1995, Volume: 97, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Humans; Mu

1995
Controversies in the treatment of cytomegalovirus retinitis: foscarnet versus ganciclovir.
    Infectious agents and disease, 1995, Volume: 4, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus R

1995
Nephrogenic diabetes insipidus and renal tubular acidosis secondary to foscarnet therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 27, Issue:3

    Topics: Acidosis, Renal Tubular; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalov

1996
A foveal-sparing pattern of cytomegalovirus retinitis in the acquired immunodeficiency syndrome.
    Australian and New Zealand journal of ophthalmology, 1996, Volume: 24, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease P

1996
Current management of cytomegalovirus retinitis in AIDS update on ganciclovir and foscarnet for CMV infections.
    Advances in experimental medicine and biology, 1996, Volume: 394

    Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cytomegalovirus Retinitis; Foscarn

1996
[Treatment of cytomegalovirus infections in HIV infection].
    Presse medicale (Paris, France : 1983), 1996, Dec-14, Volume: 25, Issue:39

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Cytomegalovirus

1996
Pharmacologic management of cytomegalovirus retinitis: review of current and future therapeutic modalities.
    Journal of the American Optometric Association, 1997, Volume: 68, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Ganci

1997
Cytomegalovirus retinitis: diagnosis and status of systemic therapy.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Diagnosis, Diffe

1997
Management strategies for patients with cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalo

1997
Therapeutic options for resistant cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus

1997
Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
    The New England journal of medicine, 1997, Jul-10, Volume: 337, Issue:2

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalo

1997
Management of CMV retinitis in HIV infected patients.
    Genitourinary medicine, 1997, Volume: 73, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytome

1997
New treatment options for CMV retinitis in AIDS.
    Advance for nurse practitioners, 1997, Volume: 5, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Co

1997
[Cytomegalovirus retinitis].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retin

1998
Local therapy for cytomegalovirus retinitis.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:2

    Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; C

1998
Cidofovir in the treatment of cytomegalovirus (CMV) retinitis.
    Ocular immunology and inflammation, 1998, Volume: 6, Issue:3

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclo

1998
Clinically resistant cytomegalovirus retinitis.
    Seminars in ophthalmology, 1995, Volume: 10, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis;

1995
Cytomegalovirus retinitis in the era of highly active antiretroviral therapy (HAART).
    The American journal of the medical sciences, 1999, Volume: 317, Issue:5

    Topics: Antiviral Agents; Biomarkers; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Diagnosis, Differentia

1999
Comparative tolerability of therapies for cytomegalovirus retinitis.
    Drug safety, 1999, Volume: 21, Issue:3

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; HIV Infections; Humans

1999
Management of CMV infections in HIV-infected patients.
    Advances in experimental medicine and biology, 1999, Volume: 458

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytos

1999
Cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
    Postgraduate medical journal, 1999, Volume: 75, Issue:888

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ga

1999
Therapeutic developments in cytomegalovirus retinitis.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:2

    Topics: Adenine; Antibodies, Monoclonal; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; D

2000
Economic evaluation of systemic treatments for cytomegalovirus retinitis in patients with AIDS.
    PharmacoEconomics, 2001, Volume: 19, Issue:5 Pt 2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis

2001
Management of CMV disease in HIV infection.
    International journal of STD & AIDS, 1999, Volume: 10, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto

1999

Trials

28 trials available for foscarnet and Cytomegaloviral Retinitis

ArticleYear
Visual loss in patients with cytomegalovirus retinitis and acquired immunodeficiency syndrome before widespread availability of highly active antiretroviral therapy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Monoclonal; Antiretroviral Therapy, Highly

2003
Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis.
    The Journal of infectious diseases, 2003, Mar-01, Volume: 187, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cohort Studies; Cytomegalovirus; Cyt

2003
A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus re
    Antiviral research, 2004, Volume: 64, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Monoclonal; Antiviral Agents; Cytomegalovi

2004
Antiviral effects of foscarnet and ganciclovir therapy on human immunodeficiency virus p24 antigen in patients with AIDS and cytomegalovirus retinitis. Studies of Ocular Complications of AIDS Research Group in collaboration with AIDS Clinical Trials Group
    The Journal of infectious diseases, 1995, Volume: 172, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antigen-Antibody Complex; Cytomegalovirus Retinitis; Female;

1995
Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis.
    Clinical pharmacology and therapeutics, 1995, Volume: 57, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Administration Schedul

1995
Dose-related difference in progression rates of cytomegalovirus retinopathy during foscarnet maintenance therapy. AIDS Clinical Trials Group Protocol 915 Team.
    American journal of ophthalmology, 1995, Volume: 119, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Re

1995
Morbidity and toxic effects associated with ganciclovir or foscarnet therapy in a randomized cytomegalovirus retinitis trial. Studies of ocular complications of AIDS Research Group, in collaboration with the AIDS Clinical Trials Group.
    Archives of internal medicine, 1995, Jan-09, Volume: 155, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retin

1995
Foscarnet or ganciclovir for treatment of AIDS and CMV retinitis.
    The American journal of medicine, 1995, Volume: 98, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Clinical Trials as Topic; Cytomegalovirus Retinitis; Foscarne

1995
Phase II dose-ranging trial of foscarnet salvage therapy for cytomegalovirus retinitis in AIDS patients intolerant of or resistant to ganciclovir (ACTG protocol 093). AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases.
    AIDS (London, England), 1994, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Resi

1994
Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. 4. Visual outcomes. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group.
    Ophthalmology, 1994, Volume: 101, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Female; Foscarnet; Fundus O

1994
Pharmacodynamic relationship of pharmacokinetic parameters of maintenance doses of foscarnet and clinical outcome of cytomegalovirus retinitis.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Chromatography, High Pressure Liquid; C

1994
High dose intravitreal foscarnet in the treatment of cytomegalovirus retinitis in AIDS.
    The British journal of ophthalmology, 1994, Volume: 78, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Female; Foscarnet; Humans;

1994
Effect of foscarnet induction treatment on quantitation of human cytomegalovirus (HCMV) DNA in peripheral blood polymorphonuclear leukocytes and aqueous humor of AIDS patients with HCMV retinitis. The Italian Foscarnet Study Group.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Aqueous Humor; Cytomegalovirus; Cytomegalovirus Retini

1994
Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The Cytomegalovirus Retreatment Trial. The Studies of Ocular Complications of AIDS Research Group in Collaboration
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Ther

1996
Controversies in the treatment of cytomegalovirus retinitis: foscarnet versus ganciclovir.
    Infectious agents and disease, 1995, Volume: 4, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus R

1995
Assessment of cytomegalovirus retinitis. Clinical evaluation vs centralized grading of fundus photographs. Studies of Ocular Complications of AIDS Research Group, AIDS Clinical Trials Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease P

1996
Measuring visual function and quality of life in patients with cytomegalovirus retinitis. Development of a questionnaire. Studies of Ocular Complication of AIDS Research Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cross-Sectional Studies; Cytomegalov

1996
Clinical vs photographic assessment of treatment of cytomegalovirus retinitis. Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial Report 8. Studies of Ocular Complications of AIDS Research Group, AIDS Clinical Trials Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet

1996
CMV retinitis: ganciclovir/monoclonal antibody.
    Antiviral research, 1996, Volume: 29, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antibodies, Monoclonal; Antiviral Agents; Cytomegalovirus Retini

1996
Design of clinical trials for drug combinations: cytomegalovirus retinitis--foscarnet and ganciclovir. The CMV retinitis retreatment trial.
    Antiviral research, 1996, Volume: 29, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Retinitis; Disease Progression

1996
Relationship between foscarnet exposure, baseline cytomegalovirus (CMV) blood culture and the time to progression of CMV retinitis in HIV-positive patients.
    AIDS (London, England), 1996, Volume: 10, Issue:10

    Topics: Analysis of Variance; Antiviral Agents; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Disea

1996
Convenient twice daily foscarnet in induction therapy of AIDS-associated cytomegalovirus retinitis. The Foscarnet Italian Study Group.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Admi

1997
[Prophylaxis secondary to retinitis by CMV in patients with AIDS: the efficacy of an intermittent schedule of 3 days/week].
    Enfermedades infecciosas y microbiologia clinica, 1997, Volume: 15, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Admi

1997
Rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis: the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS (SOCA) Research Group in Collaboration with the AIDS Clinical Trials Group
    American journal of ophthalmology, 1997, Volume: 124, Issue:1

    Topics: Adolescent; Adult; Age Factors; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphoc

1997
Comparison of pharmacokinetics and dynamics of two dosage regimens of foscarnet in AIDS patients with Cytomegalovirus retinitis.
    European journal of clinical pharmacology, 1997, Volume: 52, Issue:5

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Calcium; Cytomegalovirus

1997
Cytomegalovirus retinitis in advanced HIV-infected patients treated with protease inhibitors: incidence and outcome over 2 years.
    Journal of acquired immune deficiency syndromes (1999), 1999, Nov-01, Volume: 22, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Drug

1999
Risk factors for advancement of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. Studies of Ocular Complications of AIDS Research Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2000, Volume: 118, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD8-Positive T-Lymphocytes; Cytomegalovirus

2000
New trial for CMV retinitis.
    Treatment review, 1995, Issue:no 20

    Topics: Antibodies; Antiviral Agents; Combined Modality Therapy; Cytomegalovirus Retinitis; Foscarnet; Ganci

1995

Other Studies

132 other studies available for foscarnet and Cytomegaloviral Retinitis

ArticleYear
Efficacy of ganciclovir versus foscarnet in ganciclovir-resistant cytomegalovirus retinitis: A case report.
    European journal of ophthalmology, 2023, Volume: 33, Issue:5

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Humans; Male; Middle Aged; Trea

2023
Acute Retinal Necrosis: Virological Features Using Quantitative Polymerase Chain Reaction, Therapeutic Management, and Clinical Outcomes.
    American journal of ophthalmology, 2019, Volume: 208

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Aqueous Humor; Cytomegalovirus Retinitis; DNA, Vir

2019
Foscarnet calcium microcrystals as the intravitreal drug depot.
    Chemical communications (Cambridge, England), 2017, May-04, Volume: 53, Issue:37

    Topics: Animals; Antiviral Agents; Crystallization; Cytomegalovirus Retinitis; Foscarnet; Intravitreal Injec

2017
Optic Nerve Swelling in a Patient With Cancer.
    JAMA ophthalmology, 2018, 10-01, Volume: 136, Issue:10

    Topics: Antiviral Agents; Aqueous Humor; Cytomegalovirus; Cytomegalovirus Retinitis; Diagnosis, Differential

2018
Cytomegalovirus retinitis in the absence of AIDS.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2013, Volume: 48, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; DNA, V

2013
Chronic retinal necrosis: cytomegalovirus necrotizing retinitis associated with panretinal vasculopathy in non-HIV patients.
    Retina (Philadelphia, Pa.), 2013, Volume: 33, Issue:9

    Topics: Aged; Aged, 80 and over; Antiviral Agents; Aqueous Humor; CD4 Lymphocyte Count; Chronic Disease; Cyt

2013
Management of ganciclovir-resistant cytomegalovirus retinitis in HIV infection in the era of antiretroviral therapy.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:11

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; HIV I

2014
Intravitreal foscarnet for recurring CMV retinitis in a congenitally infected premature infant.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2014, Volume: 18, Issue:1

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Female; Foscarnet; Ganciclovir; Gestational Age; Humans

2014
Cytomegalovirus retinitis in HIV-negative patients: a practical management approach.
    Ophthalmology, 2015, Volume: 122, Issue:4

    Topics: Adult; Aged; Antigens, Viral; Antiviral Agents; Child, Preschool; Cytomegalovirus; Cytomegalovirus R

2015
Perivascular hypofluorescence in frosted branch angiitis.
    Ophthalmic surgery, lasers & imaging retina, 2015, Volume: 46, Issue:3

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count;

2015
Management of cytomegalovirus retinitis in HIV infection in the era of highly active antiretroviral therapy.
    International journal of STD & AIDS, 2015, Volume: 26, Issue:10

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Human

2015
Dual Intravitreal Injections With Foscarnet and Ganciclovir for Ganciclovir-Resistant Recurrent Cytomegalovirus Retinitis in a Congenitally Infected Infant.
    Journal of pediatric ophthalmology and strabismus, 2016, Oct-22, Volume: 53

    Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resistance, Viral; Drug Therapy,

2016
Case report: persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes.
    Journal of medical virology, 2008, Volume: 80, Issue:10

    Topics: Alemtuzumab; Anemia, Refractory, with Excess of Blasts; Antibodies, Monoclonal; Antibodies, Monoclon

2008
Cytomegalovirus retinitis.
    Ophthalmology, 2009, Volume: 116, Issue:4

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antibo

2009
Mortality associated with resistant cytomegalovirus among patients with cytomegalovirus retinitis and AIDS.
    Ophthalmology, 2010, Volume: 117, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agent

2010
Sustained release of ganciclovir and foscarnet from biodegradable scleral plugs for the treatment of cytomegalovirus retinitis.
    Biomaterials, 2010, Volume: 31, Issue:7

    Topics: Animals; Biocompatible Materials; Chromatography, High Pressure Liquid; Conjunctiva; Cytomegalovirus

2010
Fundus autofluorescence changes in cytomegalovirus retinitis.
    Retina (Philadelphia, Pa.), 2010, Volume: 30, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antiviral Agents; Cytomegalovirus Retinitis; Drug Implants; Femal

2010
Polymerase chain reaction-based ganciclovir resistance testing of ocular fluids for cytomegalovirus retinitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Volume: 130, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Aqueous Humor; Cytomegalovirus; Cytomegalovirus Retinitis; DNA-Direct

2012
Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma.
    Journal of clinical microbiology, 2012, Volume: 50, Issue:5

    Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral

2012
Retinitis from cytomegalovirus during maintenance treatment for acute lymphoblastic leukemia.
    Pediatrics international : official journal of the Japan Pediatric Society, 2012, Volume: 54, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antiviral Agents; Child; Cytomegalovirus Retinitis; Drug Therapy, C

2012
Crystallization after intravitreous foscarnet injections.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Volume: 130, Issue:5

    Topics: Antiviral Agents; Crystallization; Cytomegalovirus Retinitis; Female; Foscarnet; Humans; Intravitrea

2012
A possible coincidence of cytomegalovirus retinitis and intraocular lymphoma in a patient with systemic non-Hodgkin's lymphoma.
    Virology journal, 2013, Jan-07, Volume: 10

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antiviral Agents; Cytomegalovirus; Cy

2013
CMV retinitis after allogeneic bone marrow transplantation: a report of five cases.
    Transplant infectious disease : an official journal of the Transplantation Society, 2002, Volume: 4, Issue:2

    Topics: Acyclovir; Adult; Antiviral Agents; Bone Marrow Transplantation; Cytomegalovirus Retinitis; Female;

2002
[Bilateral uveitis with definitive hypotony caused by systemic cidofovir].
    Journal francais d'ophtalmologie, 2003, Volume: 26, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine;

2003
[Acute retinal necrosis: clinical presentation, treatment, and prognosis in a series of 22 patients].
    Journal francais d'ophtalmologie, 2004, Volume: 27, Issue:1

    Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Combi

2004
Macular CMV retinitis: a case report.
    Bulletin de la Societe belge d'ophtalmologie, 2004, Issue:293

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Fatal Out

2004
Intravitreal foscarnet for cytomegalovirus retinitis in patients with AIDS.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88, Issue:1

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Fem

2005
FDA notifications. FDA approves generic foscarnet sodium injection.
    AIDS alert, 2005, Volume: 20, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Approval; F

2005
Cytomegalovirus retinitis after fluocinolone acetonide (Retisert) implant.
    American journal of ophthalmology, 2007, Volume: 143, Issue:2

    Topics: Aged; Antiviral Agents; Behcet Syndrome; Cytomegalovirus Retinitis; Drug Implants; Fluocinolone Acet

2007
Clinical features and outcomes of cytomegalovirus retinitis after transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2008, Volume: 10, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Cytomegalovirus Retinitis; Female; Foscarnet; Ganciclovir; Hematopoie

2008
A penile ulceration in a patient with the acquired immunodeficiency syndrome. Foscarnet-induced penile ulceration.
    Archives of dermatology, 1995, Volume: 131, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; H

1995
Intravitreous and plasma concentrations of ganciclovir and foscarnet after intravenous therapy in patients with AIDS and cytomegalovirus retinitis.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus Retinitis; Drug Therapy, Combination; Fem

1995
Crescentic glomerulonephritis and crystals within glomerular capillaries in an AIDS patient treated with foscarnet.
    American journal of nephrology, 1995, Volume: 15, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Crystallization; Cytomegalovirus Retinitis; Foscarnet;

1995
A sensitive and specific polymerase chain reaction-based assay for the diagnosis of cytomegalovirus retinitis.
    American journal of ophthalmology, 1995, Volume: 120, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Base Sequence; Cytomegalovirus; Cytomegalovirus Retinitis; DN

1995
Cytomegalovirus encephalitis resistant to anti-cytomegalovirus therapy.
    AIDS (London, England), 1995, Volume: 9, Issue:5

    Topics: Bone Marrow Transplantation; Child, Preschool; Cytomegalovirus Infections; Cytomegalovirus Retinitis

1995
Cytomegalovirus ventriculoencephalitis in AIDS patients.
    Scandinavian journal of infectious diseases, 1995, Volume: 27, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Autopsy; Brain; Cerebral Ventricles; Cerebrospinal Flu

1995
Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir.
    American journal of ophthalmology, 1995, Volume: 119, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus; Cytomegalovirus Retinitis; Disease Pr

1995
Intraocular sustained drug release devices.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Delayed-Action Preparations; Drug

1995
Phosphonoformate for CMV retinitis in AIDS.
    The American journal of medicine, 1995, Volume: 98, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Administration Schedule; Fosc

1995
Resolution of oral hairy leukoplakia during treatment with foscarnet.
    AIDS (London, England), 1994, Volume: 8, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Herpesviridae In

1994
[Foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome].
    Nippon Ganka Gakkai zasshi, 1994, Volume: 98, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Re

1994
Efficacy of intravitreal foscarnet in a patient with AIDS.
    The New England journal of medicine, 1994, Mar-24, Volume: 330, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Humans; Injections; Mal

1994
In vitro anti-human cytomegalovirus activity of liposome-encapsulated foscarnet.
    German journal of ophthalmology, 1994, Volume: 3, Issue:1

    Topics: Cells, Cultured; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Carriers; Fibroblasts; Foscarnet;

1994
Retinal detachment in patients with acquired immunodeficiency syndrome.
    German journal of ophthalmology, 1994, Volume: 3, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Follow-Up Studie

1994
The development of cytomegalovirus encephalitis in AIDS patients receiving ganciclovir.
    The American journal of medicine, 1994, Volume: 96, Issue:5

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Cerebral Ventricles; Confusion; Cytomegalovirus

1994
Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis.
    American journal of ophthalmology, 1994, Jun-15, Volume: 117, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Administration Schedul

1994
Combination ganciclovir and foscarnet in the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Resistance, Microbial;

1993
Cytomegalovirus resistant to foscarnet: clinicovirologic correlation in a patient with human immunodeficiency virus.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:5

    Topics: Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resistance, Microbial; Foscarnet; Ganciclovir; HIV

1993
[Herpes zoster during foscarnet treatment in an AIDS patient].
    Medicina clinica, 1993, Oct-16, Volume: 101, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis

1993
Long-term visual morbidity of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
    Ophthalmology, 1993, Volume: 100, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Hum

1993
Risk factors for development of rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis.
    American journal of ophthalmology, 1993, Dec-15, Volume: 116, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Follow-Up Studies; Foscarnet; Ganc

1993
Ganciclovir intraocular device and patient survival.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1994, Volume: 112, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis

1994
Ganciclovir intraocular device and patient survival.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1994, Volume: 112, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis

1994
Therapy for cytomegalovirus retinitis: still no silver lining.
    JAMA, 1996, Jan-10, Volume: 275, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus R

1996
[Clinical manifestations and course of cytomegalovirus colitis in AIDS patients].
    Schweizerische medizinische Wochenschrift, 1995, Dec-16, Volume: 125, Issue:50

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cohort Studies; Colitis; Colonoscopy

1995
Antineurofilament and antiretinal antibodies in AIDS patients with cytomegalovirus retinitis.
    Clinical and diagnostic laboratory immunology, 1994, Volume: 1, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antibodies; Antiviral Agents; Cytomegalovirus Retinitis; Foscarn

1994
Pre-treatment with hydration and electrolytes may prevent dose limiting toxicities during foscarnet induction therapy.
    Genitourinary medicine, 1995, Volume: 71, Issue:6

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Electrolytes; Foscarnet; Humans; Premedication; Prospec

1995
Ganciclovir in cytomegalovirus retinitis.
    The Journal of infection, 1995, Volume: 31, Issue:3

    Topics: Adult; Antiviral Agents; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Drug Therapy, Combin

1995
Renal tubular acidosis following treatment with foscarnet.
    AIDS (London, England), 1995, Volume: 9, Issue:12

    Topics: Acidosis, Renal Tubular; Adult; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; HIV Seroposi

1995
Treatment of clinically resistant cytomegalovirus retinitis with combined intravitreal injections of ganciclovir and foscarnet.
    American journal of ophthalmology, 1996, Volume: 122, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Ret

1996
Ocular iontophoretic supplementation of intravenous foscarnet therapy.
    American journal of ophthalmology, 1996, Volume: 122, Issue:1

    Topics: Animals; Antiviral Agents; Biological Availability; Chromatography, High Pressure Liquid; Cytomegalo

1996
Cytomegalovirus retinitis and viral resistance. Prevalence of resistance at diagnosis, 1994. Cytomegalovirus Retinitis and Viral Resistance Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Cytomegalovirus; Cytomega

1996
Occurrence of cytomegalovirus retinitis after human immunodeficiency virus immunosuppression.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lympho

1996
Serous retinal detachments in a patient with clinically resistant cytomegalovirus retinitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomega

1996
New developments in the treatment of CMV retinitis.
    Ophthalmology, 1996, Volume: 103, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytos

1996
[Current status of the management of cytomegalovirus retinitis in patients with AIDS].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Ganciclo

1996
Current and experimental therapeutic options for cytomegalovirus disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Apr-15, Volume: 53, Issue:8 Suppl 2

    Topics: Administration, Oral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cyto

1996
Current management of cytomegalovirus infection: treatment and prophylaxis.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Apr-15, Volume: 53, Issue:8 Suppl 2

    Topics: Administration, Oral; Anti-Bacterial Agents; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Reti

1996
Nephrogenic diabetes insipidus associated with foscarnet--a case report.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1996
Rapid development of renal insufficiency with the simultaneous administration of amphotericin B and foscarnet.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiviral Agents; C

1996
Cytomegalovirus papillitis in patients with acquired immune deficiency syndrome. Visual prognosis of patients treated with ganciclovir and/or foscarnet.
    Ophthalmology, 1996, Volume: 103, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Cytomega

1996
Cytomegalovirus retinitis associated with Hodgkin's disease.
    Retina (Philadelphia, Pa.), 1996, Volume: 16, Issue:4

    Topics: Adult; Antiviral Agents; Biopsy; Cytomegalovirus; Cytomegalovirus Retinitis; DNA, Viral; Fluorescein

1996
Combined ganciclovir and foscarnet in pediatric cytomegalovirus retinitis.
    Journal of the National Medical Association, 1996, Volume: 88, Issue:10

    Topics: Child, Preschool; Cytomegalovirus Retinitis; Drug Therapy, Combination; Enzyme Inhibitors; Female; F

1996
[Genital ulcers from foscarnet: three cases].
    Medicina clinica, 1996, Sep-14, Volume: 107, Issue:8

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Genital Diseases, Male; Humans; Male; Ulcer

1996
[Long term survival in an HIV-immunosuppressed patient treated with foscarnet].
    Anales de medicina interna (Madrid, Spain : 1984), 1996, Volume: 13, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cytomegaloviru

1996
Changes in HIV-1 RNA plasma level in patients treated with foscarnet.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Jan-01, Volume: 14, Issue:1

    Topics: Anti-HIV Agents; Cytomegalovirus Retinitis; Foscarnet; HIV Infections; HIV-1; Humans; RNA, Viral

1997
Combined intravenous ganciclovir and foscarnet for children with recurrent cytomegalovirus retinitis.
    Ophthalmology, 1995, Volume: 102, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Cytomegalovirus Re

1995
Central venous line infections in AIDS.
    The Journal of infection, 1997, Volume: 34, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1997
Cytomegalovirus retinitis: decreased risk of bilaterality with increased use of systemic treatment. Swiss HIV Cohort Study Group.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:4

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Drug Therapy, Combination;

1997
Re-evaluation of time to progression of foscarnet salvage therapy for cytomegalovirus retinitis in AIDS patients clinically resistant to ganciclovir.
    AIDS (London, England), 1997, Volume: 11, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease Progress

1997
Identification and treatment of cytomegalovirus retinitis in patients with AIDS.
    Journal of the American Academy of Nurse Practitioners, 1997, Volume: 9, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retin

1997
Successful treatment of severe cytomegalovirus retinitis with foscarnet and intraocular injection of ganciclovir in a myelosuppressed unrelated bone marrow transplant patient.
    Bone marrow transplantation, 1997, Volume: 20, Issue:9

    Topics: Adult; Antiviral Agents; Aqueous Humor; Bone Marrow Transplantation; Cytomegalovirus Retinitis; Fema

1997
Intravitreal ganciclovir treatment in progressive outer retinal necrosis.
    American journal of ophthalmology, 1997, Volume: 124, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease P

1997
Therapy with a combination of intravitreal foscarnet and intravenous ganciclovir in clinically resistant cytomegalovirus retinitis and patients with acquired immunodeficiency syndrome.
    German journal of ophthalmology, 1996, Volume: 5, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus R

1996
New issues in the management of cytomegalovirus retinitis in AIDS patients.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Feb-15, Volume: 55, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytos

1998
Cystoid macular edema associated with cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
    American journal of ophthalmology, 1998, Volume: 125, Issue:3

    Topics: Acetazolamide; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents, Non-Steroidal

1998
Long-lasting remission of cytomegalovirus retinitis without maintenance therapy in human immunodeficiency virus-infected patients.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cytomegalovirus

1998
The progressive outer retinal necrosis syndrome: successful treatment with combination antiviral therapy.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:3

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis

1998
Lack of efficacy of cidofovir in treating AIDS-related cytomegalovirus retinitis after long-term treatment with ganciclovir.
    AIDS (London, England), 1998, Apr-16, Volume: 12, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytomegalovirus Retinitis;

1998
Prophylactic argon laser coagulation for rhegmatogenous retinal detachment in AIDS patients with cytomegalovirus retinitis.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1998, Volume: 236, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Fundu

1998
Immunohistochemical localization of ganciclovir in the human retina.
    Current eye research, 1998, Volume: 17, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Delayed-A

1998
Evaluation of cytomegalovirus retinitis management. Outcome of four years of cytomegalovirus therapy.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1998, Volume: 212, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Body Fluids; CD4 Lymphocyte Count; Cytomega

1998
Mutation in region III of the DNA polymerase gene conferring foscarnet resistance in cytomegalovirus isolates from 3 subjects receiving prolonged antiviral therapy.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Alanine; Antiviral Agents; Cytomegalovirus; Cytomegalo

1998
Incidence of foscarnet resistance and cidofovir resistance in patients treated for cytomegalovirus retinitis. The Cytomegalovirus Retinitis and Viral Resistance Study Group.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:9

    Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Resistance; Female; Fo

1998
Identification of crystals in kidneys of AIDS patients treated with foscarnet.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 32, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1998
Foscarnet crystal deposition and renal failure.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 32, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Crystallization; Cytomegalovirus Retinitis;

1998
Cytomegalovirus retinitis and viral resistance: 3. Culture results. CMV Retinitis and Viral Resistance Study Group.
    American journal of ophthalmology, 1998, Volume: 126, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Blood; Cidofovir; Cytomeg

1998
Transient foscarnet-induced hypercalcaemia.
    AIDS (London, England), 1998, Oct-01, Volume: 12, Issue:14

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Female; F

1998
In vitro antiviral susceptibilities of isolates from cytomegalovirus retinitis patients receiving first- or second-line cidofovir therapy: relationship to clinical outcome.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:6

    Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance,

1998
Foscarnet.
    Pediatrics in review, 1998, Volume: 19, Issue:12

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Herpesviridae Infections; Humans

1998
Risk of developing CMV retinitis following non-ocular CMV end organ disease in AIDS patients.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Biopsy; Cytomegalovirus Infections;

1998
[Treatment of CMV retinitis with intravitreal foscarnet].
    Journal francais d'ophtalmologie, 1998, Volume: 21, Issue:10

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease Progress

1998
[Cytomegalovirus (CMV) retinitis in AIDS. Gancilovir implantation in comparison with systemic therapy].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1999, Volume: 96, Issue:1

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cyto

1999
Intravitreal toxicology in rabbits of two preparations of 1-O-octadecyl-sn-glycerol-3-phosphonoformate, a sustained-delivery anti-CMV drug.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:7

    Topics: Animals; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Delayed-Action Preparations;

1999
Kaposi's sarcoma and non-Hodgkin's lymphoma incidence trends in AIDS Clinical Trial Group study participants.
    Journal of acquired immune deficiency syndromes (1999), 1999, Aug-01, Volume: 21 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Clinical Trials as Topic;

1999
Survival differences associated with treatment of cytomegalovirus retinitis in Maryland patients with AIDS, 1987-1994.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Jul-01, Volume: 56, Issue:13

    Topics: Adult; Age Factors; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cytome

1999
Cidofovir: new preparation. Of help in CMV retinitis.
    Prescrire international, 1998, Volume: 7, Issue:37

    Topics: Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclo

1998
Ganciclovir resistance: a matter of time and titre.
    Lancet (London, England), 2000, Aug-19, Volume: 356, Issue:9230

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; C

2000
CMV complications in common variable immunodeficiency.
    Immunobiology, 2000, Volume: 202, Issue:2

    Topics: Adult; Antiviral Agents; Azathioprine; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lym

2000
[Stopping secondary prevention in AIDS patients with inactive CMV retinitis treated with HAART (highly active antiretroviral therapy)].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2000, Volume: 97, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cido

2000
A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Re

2000
Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jan-15, Volume: 32, Issue:2

    Topics: Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cyt

2001
Frosted branch angiitis in a child with HIV infection.
    American journal of ophthalmology, 2001, Volume: 131, Issue:3

    Topics: Antiviral Agents; Child; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Glucocorticoids; HIV Inf

2001
High-dose intravitreal ganciclovir and foscarnet for cytomegalovirus retinitis.
    American journal of ophthalmology, 2001, Volume: 131, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Ther

2001
CMV retinitis: a clinical management update.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Algorithms; Antiviral Agents; Cidofovir; Clinical Protocols;

1996
Support for new foscarnet indication for AIDS-related CMV retinitis is mixed.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Combination

1997
Advances in the treatment of CMV.
    PI perspective, 1995, Issue:no 16

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topi

1995
New developments in the delivery of ganciclovir for cytomegalovirus (CMV retinitis).
    STEP perspective, 1995,Summer, Volume: 7, Issue:2

    Topics: Administration, Oral; Cytomegalovirus Retinitis; Drug Costs; Drug Implants; Foscarnet; Ganciclovir;

1995
New drug applications sought.
    AIDS alert, 1995, Volume: 10, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Clarithromycin; Cytomegalovirus Retinitis; Drug Approval; Dru

1995
Medicare may not reimburse for certain AIDS and cancer drugs.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1995

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Hu

1995
Advances in treatment for cytomegalovirus retinitis.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1995

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Antiviral Agents; Cytomegalovirus Retiniti

1995
Combination therapy improves CMV treatment.
    AIDS alert, 1996, Volume: 11, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Combi

1996
Detecting CMV retinitis: know what to look for. Treatment is effective but not pleasant.
    AIDS alert, 1996, Volume: 11, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Antiviral Agents; Cytomegalovirus Retiniti

1996
CMV: the other virus.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:3

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retin

1996
Intraocular therapy for cytomegalovirus retinitis.
    Journal of the International Association of Physicians in AIDS Care, 1996, Volume: 2, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Dr

1996
Spectrum and treatment of cytomegalovirus disease in persons with AIDS.
    Journal of the International Association of Physicians in AIDS Care, 1996, Volume: 2, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Central Nervous System Diseases; Cy

1996
Two-drug treatment effective against recurrent CMV retinitis.
    NIAID AIDS agenda, 1996

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Co

1996
Foscavir receives new indication.
    AIDS alert, 1997, Volume: 12, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Co

1997
Fomivirsen.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytome

1998
Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis after stem cell transplantation: effective monitoring of CMV infection by quantitative analysis of CMV mRNA.
    Bone marrow transplantation, 2001, Volume: 27, Issue:11

    Topics: Adolescent; Antiviral Agents; Child; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resistance, Vi

2001
Cytomegalovirus ventriculoencephalitis in a bone marrow transplant recipient receiving antiviral maintenance: clinical and molecular evidence of drug resistance.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Nov-01, Volume: 33, Issue:9

    Topics: Antiviral Agents; Bone Marrow Transplantation; Cerebral Ventricles; Child; Cidofovir; Cytomegaloviru

2001
Clinicopathologic reports, case reports, and small case series: cytomegalovirus retinitis in patients with Good syndrome.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2002, Volume: 120, Issue:4

    Topics: Agammaglobulinemia; Aged; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; DNA, Viral;

2002