Page last updated: 2024-10-27

foscarnet and Complication, Postoperative

foscarnet has been researched along with Complication, Postoperative in 27 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Research Excerpts

ExcerptRelevanceReference
" We describe a case of a cytomegalovirus (CMV)-seronegative kidney transplant recipient from a CMV-seropositive donor, whose course was complicated during valganciclovir prophylaxis by CMV disease, ultimately progressing to ganciclovir, foscarnet, and cidofovir resistance."7.85Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report. ( Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L, 2017)
"We present the case of a lung transplant recipient with disseminated crystal precipitation, and granulomatous and fibrinous inflammation after therapy with foscarnet (Foscavir; AstraZeneca, Zug, Switzerland) for recurring ganciclovir-resistant cytomegalovirus (CMV) reactivation."7.78Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient. ( Boehler, A; Gaspert, A; Schuurmans, MM; Tischler, V, 2012)
"Although foscarnet is a promising alternative for the treatment of cytomegalovirus (CMV) infection, its toxicity can be significant in patients with advanced age."7.74Reduced dose of foscarnet as preemptive therapy for cytomegalovirus infection following reduced-intensity cord blood transplantation. ( Hori, A; Kami, M; Kato, D; Kusumi, E; Masuoka, K; Matsumura, T; Miyakoshi, S; Morinaga, S; Murashige, N; Narimatsu, H; Shibata, T; Taniguchi, S; Wake, A; Yuji, K, 2007)
"Cytomegalovirus (CMV) disease is a major cause of morbidity and mortality after lung transplantation despite ganciclovir prophylaxis."7.74A single-center experience with ganciclovir-resistant cytomegalovirus in lung transplant recipients: treatment and outcome. ( Hanson, KE; Palmer, SM; Reddy, AJ; Zaas, AK, 2007)
"A case of acyclovir-resistant herpes simplex virus keratouveitis after penetrating keratoplasty is reported."7.68Acyclovir-resistant herpes simplex virus keratouveitis after penetrating keratoplasty. ( Baratz, KH; Cobo, LM; Frothingham, R; Sonkin, PL, 1992)
" We describe a case of a cytomegalovirus (CMV)-seronegative kidney transplant recipient from a CMV-seropositive donor, whose course was complicated during valganciclovir prophylaxis by CMV disease, ultimately progressing to ganciclovir, foscarnet, and cidofovir resistance."3.85Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report. ( Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L, 2017)
"We present the case of a lung transplant recipient with disseminated crystal precipitation, and granulomatous and fibrinous inflammation after therapy with foscarnet (Foscavir; AstraZeneca, Zug, Switzerland) for recurring ganciclovir-resistant cytomegalovirus (CMV) reactivation."3.78Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient. ( Boehler, A; Gaspert, A; Schuurmans, MM; Tischler, V, 2012)
"Although foscarnet is a promising alternative for the treatment of cytomegalovirus (CMV) infection, its toxicity can be significant in patients with advanced age."3.74Reduced dose of foscarnet as preemptive therapy for cytomegalovirus infection following reduced-intensity cord blood transplantation. ( Hori, A; Kami, M; Kato, D; Kusumi, E; Masuoka, K; Matsumura, T; Miyakoshi, S; Morinaga, S; Murashige, N; Narimatsu, H; Shibata, T; Taniguchi, S; Wake, A; Yuji, K, 2007)
"Cytomegalovirus (CMV) disease is a major cause of morbidity and mortality after lung transplantation despite ganciclovir prophylaxis."3.74A single-center experience with ganciclovir-resistant cytomegalovirus in lung transplant recipients: treatment and outcome. ( Hanson, KE; Palmer, SM; Reddy, AJ; Zaas, AK, 2007)
"A case of acyclovir-resistant herpes simplex virus keratouveitis after penetrating keratoplasty is reported."3.68Acyclovir-resistant herpes simplex virus keratouveitis after penetrating keratoplasty. ( Baratz, KH; Cobo, LM; Frothingham, R; Sonkin, PL, 1992)
"Treatment with foscarnet sodium and hypertonic saline was started with improvement of neurological condition within several days."1.39Severe hyponatremia caused by syndrome of inappropriate secretion of antidiuretic hormone developed as initial manifestation of human herpesvirus-6-associated acute limbic encephalitis after unrelated bone marrow transplantation. ( Abe, D; Iseki, T; Kawaguchi, T; Kawajiri, C; Nagao, Y; Nakaseko, C; Ohwada, C; Sakai, S; Sakaida, E; Shimizu, N; Sugita, Y; Takeda, Y; Takeuchi, M; Tsukamoto, S; Yamazaki, A; Yokote, K, 2013)
"Treatment with foscarnet, an inhibitor of viral-DNA polymerase, in three patients with EBV-associated post-transplant lymphoproliferative disease (PTLD) after heart (n = 2) and heart/kidney transplantation (n = 1), who did not respond to, or were not eligible for reduction of immunosuppression, resulted in complete remission (48+, 27 and 15 months respectively)."1.31Identification of early antigen BZLF1/ZEBRA protein of Epstein-Barr virus can predict the effectiveness of antiviral treatment in patients with post-transplant lymphoproliferative disease. ( Anagnostopoulos, I; Hummel, MW; Jonas, S; Oertel, SH; Riess, HB, 2002)
"Patients with multiple myeloma and lymphoma, possibly owing to a combination of disease-related characteristics and prior immunosuppressive treatment, had high rates of CMV reactivation and may require more frequent diagnostic evaluation and prompt therapeutic intervention."1.31Cytomegalovirus infection and non-neutropenic fever after autologous stem cell transplantation: high rates of reactivation in patients with multiple myeloma and lymphoma. ( Bolaños-Meade, J; Buddharaju, LN; Chen, T; Cottler-Fox, M; Cross, A; Fassas, AB; Lovchik, JC; Rapoport, A; Tricot, G, 2001)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.41)18.7374
1990's6 (22.22)18.2507
2000's13 (48.15)29.6817
2010's5 (18.52)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Kuwatsuka, Y1
Atsuta, Y1
Hirakawa, A1
Uchida, N1
Inamoto, Y1
Najima, Y1
Ikegame, K1
Eto, T1
Ozawa, Y1
Ichinohe, T1
Inoue, M1
Kimura, T1
Okamoto, S1
Miyamura, K1
Fukuda, T1
Bruminhent, J1
Rotjanapan, P1
Watcharananan, SP1
Echenique, IA1
Beltran, D1
Ramirez-Ruiz, L1
Najafian, N1
Agrawal, N1
Cintra-Cabrera, M1
Suárez-Benjumea, A1
Bernal-Blanco, G1
González-Roncero, FM1
Toapanta-Gaibor, NG1
Súñer-Poblet, M1
Pérez-Valdivia, MÁ1
Fernández-Cuenca, F1
Gentil-Govantes, MÁ1
Rocha-Castilla, JL1
Sola, E1
Vega, E1
Gutiérrez, C1
López, V1
Cabello, M1
Burgos, D1
González Molina, M1
Siles, J1
Travi, G1
Pergam, SA1
Xie, H1
Boeckh, MJ1
Tischler, V1
Schuurmans, MM1
Boehler, A1
Gaspert, A1
Kawaguchi, T1
Takeuchi, M1
Kawajiri, C1
Abe, D1
Nagao, Y1
Yamazaki, A1
Sugita, Y1
Tsukamoto, S1
Sakai, S1
Takeda, Y1
Ohwada, C1
Sakaida, E1
Shimizu, N1
Yokote, K1
Iseki, T1
Nakaseko, C1
Oertel, SH1
Anagnostopoulos, I1
Hummel, MW1
Jonas, S1
Riess, HB1
Ronghe, MD1
Foot, AB1
Cornish, JM1
Steward, CG1
Carrington, D1
Goulden, N1
Marks, DI1
Oakhill, A1
Valdez, O1
Gaspar, A1
Dickson, J1
Weigert, A1
Machado, D1
Halkic, N1
Ksontini, R1
Scholl, B1
Blanc, C1
Kovacsovics, T1
Meylan, P1
Muheim, C1
Gillet, M1
Mosimann, F1
Chen, F1
Bando, T1
Hanaoka, N1
Fukuse, T1
Hasegawa, S1
Wada, H1
Narimatsu, H1
Kami, M1
Kato, D1
Matsumura, T1
Murashige, N1
Kusumi, E1
Yuji, K1
Hori, A1
Shibata, T1
Masuoka, K1
Wake, A1
Miyakoshi, S1
Morinaga, S1
Taniguchi, S1
Reddy, AJ1
Zaas, AK1
Hanson, KE1
Palmer, SM1
Le Goff, C1
Hurault de Ligny, B1
Freymuth, F2
Cardineau, E1
Lobbedez, T1
Ryckelynck, JP1
Petitjean, J1
Eugene-Ruelland, G1
Daon, F1
Galateau, F1
Rieux, C1
Gautheret-Dejean, A1
Challine-Lehmann, D1
Kirch, C1
Agut, H1
Vernant, JP1
Cole, PD1
Stiles, J1
Boulad, F1
Small, TN1
O'Reilly, RJ1
George, D1
Szabolcs, P1
Kiehn, TE1
Kernan, NA1
Ketteler, M1
Preuschof, L1
Mertz, A1
Stöffler-Meilicke, M1
Schäfer, H1
Distler, A1
Offermann, G1
Fassas, AB1
Bolaños-Meade, J1
Buddharaju, LN1
Rapoport, A1
Cottler-Fox, M1
Chen, T1
Lovchik, JC1
Cross, A1
Tricot, G1
Crippa, F1
Corey, L1
Chuang, EL1
Sale, G1
Boeckh, M1
Greijer, AE1
Verschuuren, EA1
Dekkers, CA1
Adriaanse, HM1
van der Bij, W1
The, TH1
Middeldorp, JM1
Spratt, PM1
Sonkin, PL1
Baratz, KH1
Frothingham, R1
Cobo, LM1
Larson, A1
Frödin, L1
Tufveson, G1
Larsson, E1
Källander, CF1
Gronowitz, JS1
Gluckman, E1
Keable, H1
Meletis, J1
Bombail, D1
Jolivet, I1
Huart, JJ1
Nebout, T1
Cavazzana, M1
De Castro, H1

Reviews

2 reviews available for foscarnet and Complication, Postoperative

ArticleYear
Resistant Cytomegalovirus Infection After Renal Transplantation: Literature Review.
    Transplantation proceedings, 2018, Volume: 50, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Antiviral Agents; Basiliximab; Cytomegalovirus;

2018
[Cytomegalovirus infection after transplantation. Virological diagnosis, antiviral treatment].
    Pathologie-biologie, 1993, Volume: 41, Issue:8

    Topics: Antibodies, Viral; Antigens, Viral; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Enzyme-

1993

Other Studies

25 other studies available for foscarnet and Complication, Postoperative

ArticleYear
Use of unapproved or off-label drugs in Japan for the treatment of graft-versus-host disease and post-transplant viral infection.
    International journal of hematology, 2020, Volume: 112, Issue:6

    Topics: Acute Disease; Adult; Beclomethasone; Chronic Disease; Cidofovir; Cytomegalovirus Infections; Etaner

2020
Epidemiology and Outcome of Ganciclovir-Resistant Cytomegalovirus Infection After Solid Organ Transplantation: A Single Transplant Center Experience in Thailand.
    Transplantation proceedings, 2017, Volume: 49, Issue:5

    Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resi

2017
Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report.
    Transplantation proceedings, 2017, Volume: 49, Issue:7

    Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Respo

2017
[Disease by CMV resistant to Ganciclovir. Should plasma valganciclovir levels be monitored in high risk patients?].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2009, Volume: 29, Issue:2

    Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Monitoring; Drug Resistance, Mul

2009
Donor CMV serostatus not predictive of relapse in D-/R- pediatric HCT.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:6

    Topics: Acyclovir; Adolescent; Adult; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Child; Child, Pr

2009
Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2012, Volume: 31, Issue:9

    Topics: Adult; Antiviral Agents; Crystallization; Cytomegalovirus Infections; Foscarnet; Granuloma; Heart Di

2012
Severe hyponatremia caused by syndrome of inappropriate secretion of antidiuretic hormone developed as initial manifestation of human herpesvirus-6-associated acute limbic encephalitis after unrelated bone marrow transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2013, Volume: 15, Issue:2

    Topics: Antiviral Agents; Bone Marrow Transplantation; Diagnosis, Differential; DNA, Viral; Female; Foscarne

2013
Identification of early antigen BZLF1/ZEBRA protein of Epstein-Barr virus can predict the effectiveness of antiviral treatment in patients with post-transplant lymphoproliferative disease.
    British journal of haematology, 2002, Volume: 118, Issue:4

    Topics: Adult; Antiviral Agents; DNA-Binding Proteins; Epstein-Barr Virus Infections; Foscarnet; Gene Rearra

2002
The impact of transfusion of leucodepleted platelet concentrates on cytomegalovirus disease after allogeneic stem cell transplantation.
    British journal of haematology, 2002, Volume: 118, Issue:4

    Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cytomegalovirus Infections;

2002
Cytomegalovirus infection resistant to ganciclovir in a renal transplant patient.
    Transplantation proceedings, 2003, Volume: 35, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Antiviral Agents; Cadaver; Candidiasis; Cytomegalov

2003
Recurrent cytomegalovirus disease, visceral leishmaniosis, and Legionella pneumonia after liver transplantation: a case report.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:1

    Topics: Anti-Bacterial Agents; Antimony Sodium Gluconate; Antiviral Agents; Bone and Bones; Clarithromycin;

2004
Early onset of ganciclovir-resistant cytomegalovirus infection in a lung-transplant recipient.
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 2005, Volume: 53, Issue:10

    Topics: Adult; Antiviral Agents; Cytomegalovirus Infections; Drug Resistance, Viral; Female; Foscarnet; Ganc

2005
Reduced dose of foscarnet as preemptive therapy for cytomegalovirus infection following reduced-intensity cord blood transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2007, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Antigens, Viral; Antiviral Agents; Cord Blood Stem Cell Transplantation; Cy

2007
A single-center experience with ganciclovir-resistant cytomegalovirus in lung transplant recipients: treatment and outcome.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2007, Volume: 26, Issue:12

    Topics: Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Drug Resistance, Viral; Drug T

2007
[Quantitative cytomegaloviral leukocytic antigenemia. Clinical aspects].
    Presse medicale (Paris, France : 1983), 1995, Mar-18, Volume: 24, Issue:11

    Topics: Antigens, Viral; Cytomegalovirus; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Humans; Kidney

1995
Human herpesvirus-6 meningoencephalitis in a recipient of an unrelated allogeneic bone marrow transplantation.
    Transplantation, 1998, May-27, Volume: 65, Issue:10

    Topics: Acute Disease; Adult; Antiviral Agents; Bone Marrow Transplantation; Female; Foscarnet; Ganciclovir;

1998
Successful treatment of human herpesvirus 6 encephalitis in a bone marrow transplant recipient.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:3

    Topics: Adolescent; Antiviral Agents; Bone Marrow Transplantation; Encephalitis, Viral; Female; Foscarnet; H

1998
Fatal cytomegalovirus pneumonia after preemptive antiviral therapy in a renal transplant recipient.
    Clinical nephrology, 2000, Volume: 54, Issue:5

    Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine;

2000
Cytomegalovirus infection and non-neutropenic fever after autologous stem cell transplantation: high rates of reactivation in patients with multiple myeloma and lymphoma.
    British journal of haematology, 2001, Volume: 112, Issue:1

    Topics: Adult; Aged; Antigens, Viral; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Female;

2001
Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jan-15, Volume: 32, Issue:2

    Topics: Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cyt

2001
Expression dynamics of human cytomegalovirus immune evasion genes US3, US6, and US11 in the blood of lung transplant recipients.
    The Journal of infectious diseases, 2001, Aug-01, Volume: 184, Issue:3

    Topics: Antigens, Viral; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; DNA Primers; DNA Pro

2001
Transplantation of the heart and lung.
    The Medical journal of Australia, 1992, Oct-05, Volume: 157, Issue:7

    Topics: Australia; Coronary Artery Disease; Costs and Cost Analysis; Cytomegalovirus Infections; Foscarnet;

1992
Acyclovir-resistant herpes simplex virus keratouveitis after penetrating keratoplasty.
    Ophthalmology, 1992, Volume: 99, Issue:12

    Topics: Acyclovir; Administration, Oral; Animals; Drug Resistance, Microbial; Foscarnet; Humans; Keratitis,

1992
Deoxythymidine kinase, a possible marker for monitoring activity of cytomegalovirus infection after renal transplantation.
    Scandinavian journal of urology and nephrology, 1986, Volume: 20, Issue:1

    Topics: Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Humans; Kidney Transplantation; Male; Middl

1986
[Prevention and treatment of cytomegalovirus infections after graft of allogenic bone marrow].
    Nouvelle revue francaise d'hematologie, 1987, Volume: 29, Issue:1

    Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Cytomegalovirus Infections; Foscarnet; Gan

1987