foscarnet has been researched along with Cold Sore in 11 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aim of this post-marketing surveillance study was to generate further data on efficacy and tolerability of foscarnet sodium cream 2% in patients with recurrent herpes labialis in daily routine practice." | 9.12 | [Efficacy and tolerability of topical foscarnet sodium in treatment of herpes labialis. Results of post-marketing surveillance]. ( Braun, D; Gross, G, 2006) |
| "A topical 3% foscarnet cream formulation was evaluated for its ability to treat experimental UV radiation (UVR)-induced herpes labialis in a double-blind study." | 9.08 | Effect of foscarnet cream on experimental UV radiation-induced herpes labialis. ( Bernstein, DI; Blumberg, DA; Broberg, P; Bryson, Y; Evans, TG; Grafford, K; Martin-Munley, S; Schleupner, CJ; Spruance, SL, 1997) |
| "Aim of this post-marketing surveillance study was to generate further data on efficacy and tolerability of foscarnet sodium cream 2% in patients with recurrent herpes labialis in daily routine practice." | 5.12 | [Efficacy and tolerability of topical foscarnet sodium in treatment of herpes labialis. Results of post-marketing surveillance]. ( Braun, D; Gross, G, 2006) |
| "A topical 3% foscarnet cream formulation was evaluated for its ability to treat experimental UV radiation (UVR)-induced herpes labialis in a double-blind study." | 5.08 | Effect of foscarnet cream on experimental UV radiation-induced herpes labialis. ( Bernstein, DI; Blumberg, DA; Broberg, P; Bryson, Y; Evans, TG; Grafford, K; Martin-Munley, S; Schleupner, CJ; Spruance, SL, 1997) |
| " No significant difference in the incidence of local or systemic adverse effects was noted between the two groups." | 2.66 | Efficacy and safety of foscarnet for recurrent orolabial herpes: a multicentre randomized double-blind study. ( Aoki, FY; Lawee, D; Portnoy, J; Rosenthal, D, 1988) |
| "The mechanism of recurrence is yet not fully elucidated and therapy still remains a problem." | 2.36 | [Herpes simplex]. ( Fanta, D, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosen, T | 1 |
| Gross, G | 1 |
| Braun, D | 1 |
| Fanta, D | 1 |
| Oxford, J | 1 |
| Safrin, S | 1 |
| Kemmerly, S | 1 |
| Plotkin, B | 1 |
| Smith, T | 1 |
| Weissbach, N | 1 |
| De Veranez, D | 1 |
| Phan, LD | 1 |
| Cohn, D | 1 |
| Iino, T | 1 |
| Gondo, H | 1 |
| Ohno, Y | 1 |
| Minagawa, H | 1 |
| Iwasaki, H | 1 |
| Maruyama, T | 1 |
| Nakashima, H | 1 |
| Niho, Y | 1 |
| Slavkin, HC | 1 |
| Bernstein, DI | 1 |
| Schleupner, CJ | 1 |
| Evans, TG | 1 |
| Blumberg, DA | 1 |
| Bryson, Y | 1 |
| Grafford, K | 1 |
| Broberg, P | 1 |
| Martin-Munley, S | 1 |
| Spruance, SL | 1 |
| Ball, SC | 1 |
| Al-Samarai, A | 1 |
| Kinghorn, G | 1 |
| Potter, C | 1 |
| Lawee, D | 1 |
| Rosenthal, D | 1 |
| Aoki, FY | 1 |
| Portnoy, J | 1 |
2 reviews available for foscarnet and Cold Sore
| Article | Year |
|---|---|
[Herpes simplex].
Topics: Adolescent; Adult; Amantadine; Antigens, Viral; Cell Transformation, Viral; Female; Foscarnet; Herpe | 1981 |
Persistent herpes simplex virus infection.
Topics: Acyclovir; Adult; Female; Foscarnet; Herpes Labialis; HIV Infections; Humans; Immunocompromised Host | 2001 |
3 trials available for foscarnet and Cold Sore
| Article | Year |
|---|---|
[Efficacy and tolerability of topical foscarnet sodium in treatment of herpes labialis. Results of post-marketing surveillance].
Topics: Administration, Topical; Adolescent; Adult; Aged; Antiviral Agents; Child; Dermatologic Agents; Drug | 2006 |
Effect of foscarnet cream on experimental UV radiation-induced herpes labialis.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Double-Blind Method; Female; Foscarnet; Herpes Labialis; | 1997 |
Efficacy and safety of foscarnet for recurrent orolabial herpes: a multicentre randomized double-blind study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antiviral Agents; Clinical Trials as Topic; Double | 1988 |
6 other studies available for foscarnet and Cold Sore
| Article | Year |
|---|---|
Recurrent Herpes Labialis in Adults: New Tricks for an Old Dog.
Topics: Acyclovir; Administration, Oral; Administration, Topical; Adult; Antiviral Agents; Chronic Disease; | 2017 |
The potential of phosphonoformate for the treatment of herpex simplex labialis.
Topics: Antiviral Agents; Foscarnet; Herpes Labialis; Humans; Organophosphorus Compounds; Phosphonoacetic Ac | 1980 |
Foscarnet-resistant herpes simplex virus infection in patients with AIDS.
Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Drug Resistance, Microbial; Drug Therapy, C | 1994 |
Successful foscarnet therapy for mucocutaneous infection with herpes simplex virus in a recipient after unrelated bone marrow transplantation.
Topics: Acyclovir; Adult; Antiviral Agents; Bone Marrow Transplantation; Drug Resistance, Microbial; Foscarn | 1996 |
Infection and immunity.
Topics: Foscarnet; Herpes Labialis; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Virus Activation; Vi | 1996 |
Sensitivity of HSV clinical isolates to foscarnet and in vitro dual combination of foscarnet and acyclovir.
Topics: Acyclovir; Antiviral Agents; Drug Interactions; Foscarnet; Herpes Labialis; Humans; Microbial Sensit | 1987 |