foscarnet has been researched along with Cholera Infantum in 11 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with symptomatic gastrointestinal disease due to cytomegalovirus (CMV) were randomized to receive open-label ganciclovir (22) or foscarnet (26)." | 9.08 | Treatment of AIDS-associated gastrointestinal cytomegalovirus infection with foscarnet and ganciclovir: a randomized comparison. ( Benhamou, Y; Blanshard, C; Dohin, E; Gazzard, BG; Katlama, C; Lernestedt, JO, 1995) |
| "Patients with symptomatic gastrointestinal disease due to cytomegalovirus (CMV) were randomized to receive open-label ganciclovir (22) or foscarnet (26)." | 5.08 | Treatment of AIDS-associated gastrointestinal cytomegalovirus infection with foscarnet and ganciclovir: a randomized comparison. ( Benhamou, Y; Blanshard, C; Dohin, E; Gazzard, BG; Katlama, C; Lernestedt, JO, 1995) |
| " Adverse events resulted in discontinuance of medication in the case of one patient." | 2.68 | Treatment of gastrointestinal cytomegalovirus infection with twice-daily foscarnet: a pilot study of safety, efficacy, and pharmacokinetics in patients with AIDS. ( Dieterich, DT; Faust, MJ; Johnson, J; Lew, EA; Martin-Munley, S; Nix, D; Poles, MA, 1997) |
| "Foscarnet was administered as a continuous infusion of 200 mg/kg (prior to 1988) or as an intermittent infusion of 60 mg/kg t." | 2.67 | Treatment of HIV-related cytomegalovirus disease of the gastrointestinal tract with foscarnet. ( Blanshard, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (81.82) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Péter, A | 1 |
| Telkes, G | 1 |
| Varga, M | 1 |
| Járay, J | 1 |
| Fica, A | 1 |
| Cervera, C | 1 |
| Pérez, N | 1 |
| Marcos, MA | 1 |
| Ramírez, J | 1 |
| Linares, L | 1 |
| Soto, G | 1 |
| Navasa, M | 1 |
| Cofan, F | 1 |
| Ricart, MJ | 1 |
| Pérez-Villa, F | 1 |
| Pumarola, T | 1 |
| Moreno, A | 1 |
| Blanshard, C | 2 |
| Benhamou, Y | 1 |
| Dohin, E | 1 |
| Lernestedt, JO | 1 |
| Gazzard, BG | 1 |
| Katlama, C | 1 |
| Poles, MA | 3 |
| Lew, EA | 2 |
| Dieterich, DT | 3 |
| Dicker, M | 1 |
| Tepper, R | 1 |
| Lew, E | 1 |
| Gerna, G | 1 |
| Sarasini, A | 1 |
| Baldanti, F | 1 |
| Percivalle, E | 1 |
| Zella, D | 1 |
| Revello, MG | 1 |
| Martin-Munley, S | 1 |
| Johnson, J | 1 |
| Nix, D | 1 |
| Faust, MJ | 1 |
| Goodgame, RW | 1 |
| Drew, WL | 1 |
| Lalezari, JP | 1 |
| Williams, IG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease[NCT00002145] | Phase 3 | 145 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for foscarnet and Cholera Infantum
| Article | Year |
|---|---|
[Gastrointestinal cytomegalovirus infections in organ transplant patients].
Topics: Acyclovir; Antiviral Agents; Biopsy; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosin | 2008 |
Cytomegalovirus: disease syndromes and treatment.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Central Nervous System Diseases; Chorioreti | 1999 |
Management of CMV disease in HIV infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto | 1999 |
4 trials available for foscarnet and Cholera Infantum
| Article | Year |
|---|---|
Treatment of AIDS-associated gastrointestinal cytomegalovirus infection with foscarnet and ganciclovir: a randomized comparison.
Topics: Adult; AIDS-Related Opportunistic Infections; Antigens, Viral; Cytomegalovirus; Cytomegalovirus Infe | 1995 |
Foscarnet treatment of cytomegalovirus gastrointestinal infections in acquired immunodeficiency syndrome patients who have failed ganciclovir induction.
Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Drug Resistance; Foscarnet | 1993 |
Treatment of gastrointestinal cytomegalovirus infection with twice-daily foscarnet: a pilot study of safety, efficacy, and pharmacokinetics in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Animals; Antiviral | 1997 |
Treatment of HIV-related cytomegalovirus disease of the gastrointestinal tract with foscarnet.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Female; Foscarnet; | 1992 |
4 other studies available for foscarnet and Cholera Infantum
| Article | Year |
|---|---|
Immunohistochemically proven cytomegalovirus end-organ disease in solid organ transplant patients: clinical features and usefulness of conventional diagnostic tests.
Topics: Adult; Aged; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Disease Progression; DNA | 2007 |
Predisposition to cytomegalovirus infection of the gastrointestinal tract.
Topics: Cytomegalovirus Infections; Drug Therapy, Combination; Foscarnet; Ganciclovir; Gastrointestinal Dise | 1994 |
Quantitative systemic and local evaluation of the antiviral effect of ganciclovir and foscarnet induction treatment on human cytomegalovirus gastrointestinal disease of patients with AIDS. Italian Foscarnet GID Study Group.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections | 1997 |
How to treat the cytomegalovirus troll.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; DNA, Viral; Fos | 1998 |