Page last updated: 2024-10-27

foscarnet and Chickenpox

foscarnet has been researched along with Chickenpox in 10 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Chickenpox: A highly contagious infectious disease caused by the varicella-zoster virus (HERPESVIRUS 3, HUMAN). It usually affects children, is spread by direct contact or respiratory route via droplet nuclei, and is characterized by the appearance on the skin and mucous membranes of successive crops of typical pruritic vesicular lesions that are easily broken and become scabbed. Chickenpox is relatively benign in children, but may be complicated by pneumonia and encephalitis in adults. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" These questions concern appropriate routes of administration for antiviral compounds, optimal dosage regimens, risks of long-term prophylaxis, and the emergence of resistant organisms."2.66Antiviral chemotherapy and chemoprophylaxis. ( Dolin, R, 1985)
"There are no published data on varicella in HIV-infected adults, however, probably because most adults have already experienced varicella prior to HIV infection."2.41Prevention and treatment of VZV infections in patients with HIV. ( Gershon, AA, 2001)
"The alphaherpesvirus varicella-zoster virus (VZV) causes chickenpox and shingles."1.40β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism. ( Arnold, RD; Chavre, S; Chu, CK; De, C; Hagen, FK; Liu, D; Moffat, JF; Singh, US; White, C; Zheng, B, 2014)
"Among the atypical forms of chronic varicella, this eruption appears to be unique."1.29Chronic varicella presenting as disseminated pinpoint-sized papules in a man infected with the human immunodeficiency virus. ( Castanet, J; Durant, J; Lacour, JP; Ortonne, JP; Perrin, C; Rodot, S; Van Elslande, L, 1996)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's4 (40.00)18.2507
2000's4 (40.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De, C1
Liu, D1
Zheng, B1
Singh, US1
Chavre, S1
White, C1
Arnold, RD1
Hagen, FK1
Chu, CK1
Moffat, JF1
Brown, TJ1
McCrary, M1
Tyring, SK1
Hatchette, T1
Tipples, GA1
Peters, G1
Alsuwaidi, A1
Zhou, J1
Mailman, TL1
Sanz Moreno, J1
López-Rubio, M1
Calero-García, MA1
Ratia-Jiménez, T1
Arranz-Caso, A1
Martínez-Martínez, J1
Castanet, J1
Rodot, S1
Lacour, JP1
Van Elslande, L1
Perrin, C1
Durant, J1
Ortonne, JP1
Smith, NA1
Wood, C1
Asboe, D1
Bingham, JS1
Visse, B1
Huraux, JM1
Fillet, AM1
Crassard, N1
Souillet, AL1
Morfin, F1
Thouvenot, D1
Claudy, A1
Bertrand, Y1
Gershon, AA1
Dolin, R1

Reviews

3 reviews available for foscarnet and Chickenpox

ArticleYear
Antiviral agents: Non-antiretroviral [correction of Nonantiviral] drugs.
    Journal of the American Academy of Dermatology, 2002, Volume: 47, Issue:4

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Chickenpox; Cytomegalovirus Infections; Famciclovir; Fos

2002
Foscarnet salvage therapy for acyclovir-resistant varicella zoster: report of a novel thymidine kinase mutation and review of the literature.
    The Pediatric infectious disease journal, 2008, Volume: 27, Issue:1

    Topics: Acyclovir; Chickenpox; Child; Drug Resistance, Viral; Female; Foscarnet; Herpesvirus 3, Human; Human

2008
Prevention and treatment of VZV infections in patients with HIV.
    Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Chickenpox; Chickenpox Va

2001

Trials

1 trial available for foscarnet and Chickenpox

ArticleYear
Antiviral chemotherapy and chemoprophylaxis.
    Science (New York, N.Y.), 1985, Mar-15, Volume: 227, Issue:4692

    Topics: Acyclovir; Adult; Aged; Amantadine; Antiviral Agents; Chickenpox; Clinical Trials as Topic; Cytomega

1985

Other Studies

6 other studies available for foscarnet and Chickenpox

ArticleYear
β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.
    Antiviral research, 2014, Volume: 110

    Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chickenpox; Dioxolanes; Drug The

2014
Acute abdomen and intestinal necrosis produced by varicella-zoster virus in an immunocompromised host.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:5

    Topics: Abdomen, Acute; Aged; Antiviral Agents; Chickenpox; Fatal Outcome; Female; Foscarnet; Herpesvirus 3,

1996
Chronic varicella presenting as disseminated pinpoint-sized papules in a man infected with the human immunodeficiency virus.
    Dermatology (Basel, Switzerland), 1996, Volume: 192, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Chickenpox; Chronic Disea

1996
Topical foscarnet for aciclovir-resistant mucocutaneous herpes infections in AIDS.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Acyclovir; Administration, Topical; Antiviral Agents; Chickenpox; Drug Resistance, Microbial; Foscar

1997
Point mutations in the varicella-zoster virus DNA polymerase gene confers resistance to foscarnet and slow growth phenotype.
    Journal of medical virology, 1999, Volume: 59, Issue:1

    Topics: Amino Acid Sequence; Antiviral Agents; Chickenpox; Child; DNA-Directed DNA Polymerase; DNA, Viral; D

1999
Acyclovir-resistant varicella infection with atypical lesions in a non-HIV leukemic infant.
    Acta paediatrica (Oslo, Norway : 1992), 2000, Volume: 89, Issue:12

    Topics: Acyclovir; Antiviral Agents; Chickenpox; Drug Resistance; Foscarnet; Herpesvirus 3, Human; HIV Seron

2000