Page last updated: 2024-10-27

foscarnet and Amaurosis

foscarnet has been researched along with Amaurosis in 5 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Research Excerpts

ExcerptRelevanceReference
" Although he was given enough antiviral treatment against CMV and immunosuppression with high-dose methylprednisolone, the patient's vision showed no improvement, and he has almost total bilateral blindness."3.78Presumed cytomegalovirus-associated retrobulbar optic neuritis in a patient after allogeneic stem cell transplantation. ( Huang, Y; Pan, S; Wang, H; Wang, Z; Yan, H; Zheng, X, 2012)
"We report a case of pseudorabies virus encephalitis and endophthalmitis, diagnosed 89 days after onset, confirmed with intraocular fluid metagenomic next generation sequencing (mNGS) after the result of two cerebrospinal fluid (CSF) mNGS tests were negative."1.91A case report of long-delayed diagnosis of pseudorabies virus encephalitis with endophthalmitis: lessons from metagenomic next generation sequencing. ( Fang, L; Li, L; Liang, B; Yan, C; Zhang, Y; Zhou, Y, 2023)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Zhang, Y2
Fang, L1
Zhou, Y1
Liang, B1
Yan, C1
Li, L1
Nomura, JH1
Eichhorn, K1
Cao, TM1
Sahebi, F1
Zheng, X1
Huang, Y1
Wang, Z1
Yan, H1
Pan, S1
Wang, H1
Holbrook, JT1
Jabs, DA1
Weinberg, DV1
Lewis, RA1
Davis, MD1
Friedberg, D1
Benz, MS1
Glaser, JS1
Davis, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component[NCT00000665]240 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for foscarnet and Amaurosis

ArticleYear
Visual loss in patients with cytomegalovirus retinitis and acquired immunodeficiency syndrome before widespread availability of highly active antiretroviral therapy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Monoclonal; Antiretroviral Therapy, Highly

2003

Other Studies

4 other studies available for foscarnet and Amaurosis

ArticleYear
A case report of long-delayed diagnosis of pseudorabies virus encephalitis with endophthalmitis: lessons from metagenomic next generation sequencing.
    BMC neurology, 2023, May-16, Volume: 23, Issue:1

    Topics: Acyclovir; Antiviral Agents; Aqueous Humor; Blindness; Delayed Diagnosis; DNA, Viral; Encephalitis,

2023
Cytomegalovirus sinusitis complicated by orbital apex syndrome in an immunocompromised host.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:6

    Topics: Aged; Antiviral Agents; Biopsy; Blindness; Cytomegalovirus; Cytomegalovirus Infections; Diplopia; Ex

2016
Presumed cytomegalovirus-associated retrobulbar optic neuritis in a patient after allogeneic stem cell transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2012, Volume: 14, Issue:2

    Topics: Adult; Antiviral Agents; Blindness; Cytomegalovirus Infections; Foscarnet; Humans; Immunosuppressive

2012
Progressive outer retinal necrosis in immunocompetent patients treated initially for optic neuropathy with systemic corticosteroids.
    American journal of ophthalmology, 2003, Volume: 135, Issue:4

    Topics: Acyclovir; Aged; Antiviral Agents; Aqueous Humor; Blindness; DNA, Viral; Drug Therapy, Combination;

2003