foscarnet has been researched along with ARC in 3 studies
Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Excerpt | Relevance | Reference |
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"The drug sensitivities of human immunodeficiency virus (HIV) isolates from a group of patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) who were receiving zidovudine (3'-azido-3'-deoythymidine, AZT) therapy were tested by means of a newly developed plaque assay in CD4+ HeLa cells." | 7.67 | HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. ( Darby, G; Larder, BA; Richman, DD, 1989) |
"The drug sensitivities of human immunodeficiency virus (HIV) isolates from a group of patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) who were receiving zidovudine (3'-azido-3'-deoythymidine, AZT) therapy were tested by means of a newly developed plaque assay in CD4+ HeLa cells." | 3.67 | HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. ( Darby, G; Larder, BA; Richman, DD, 1989) |
"Foscarnet is an RT inhibitor that is a product analogue, in contrast to the widely used nucleoside analogues." | 2.69 | Pronounced anti-HIV-1 activity of foscarnet in patients without cytomegalovirus infection. ( Bergdahl, S; Jacobsson, B; Moberg, L; Sönnerborg, A, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (66.67) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bergdahl, S | 1 |
Jacobsson, B | 1 |
Moberg, L | 1 |
Sönnerborg, A | 1 |
Larder, BA | 1 |
Darby, G | 1 |
Richman, DD | 1 |
Farthing, CF | 1 |
Dalgleish, AG | 1 |
Clark, A | 1 |
McClure, M | 1 |
Chanas, A | 1 |
Gazzard, BG | 1 |
2 trials available for foscarnet and ARC
Article | Year |
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Pronounced anti-HIV-1 activity of foscarnet in patients without cytomegalovirus infection.
Topics: AIDS-Related Complex; Antiviral Agents; Foscarnet; HIV Reverse Transcriptase; HIV-1; Humans; Male; R | 1998 |
Phosphonoformate (foscarnet): a pilot study in AIDS and AIDS related complex.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antigens, Viral; Clinical Trials as Topic; | 1987 |
1 other study available for foscarnet and ARC
Article | Year |
---|---|
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Fosca | 1989 |