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foscarnet and ARC

foscarnet has been researched along with ARC in 3 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

Research Excerpts

ExcerptRelevanceReference
"The drug sensitivities of human immunodeficiency virus (HIV) isolates from a group of patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) who were receiving zidovudine (3'-azido-3'-deoythymidine, AZT) therapy were tested by means of a newly developed plaque assay in CD4+ HeLa cells."7.67HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. ( Darby, G; Larder, BA; Richman, DD, 1989)
"The drug sensitivities of human immunodeficiency virus (HIV) isolates from a group of patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) who were receiving zidovudine (3'-azido-3'-deoythymidine, AZT) therapy were tested by means of a newly developed plaque assay in CD4+ HeLa cells."3.67HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. ( Darby, G; Larder, BA; Richman, DD, 1989)
"Foscarnet is an RT inhibitor that is a product analogue, in contrast to the widely used nucleoside analogues."2.69Pronounced anti-HIV-1 activity of foscarnet in patients without cytomegalovirus infection. ( Bergdahl, S; Jacobsson, B; Moberg, L; Sönnerborg, A, 1998)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergdahl, S1
Jacobsson, B1
Moberg, L1
Sönnerborg, A1
Larder, BA1
Darby, G1
Richman, DD1
Farthing, CF1
Dalgleish, AG1
Clark, A1
McClure, M1
Chanas, A1
Gazzard, BG1

Trials

2 trials available for foscarnet and ARC

ArticleYear
Pronounced anti-HIV-1 activity of foscarnet in patients without cytomegalovirus infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, May-01, Volume: 18, Issue:1

    Topics: AIDS-Related Complex; Antiviral Agents; Foscarnet; HIV Reverse Transcriptase; HIV-1; Humans; Male; R

1998
Phosphonoformate (foscarnet): a pilot study in AIDS and AIDS related complex.
    AIDS (London, England), 1987, Volume: 1, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antigens, Viral; Clinical Trials as Topic;

1987

Other Studies

1 other study available for foscarnet and ARC

ArticleYear
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.
    Science (New York, N.Y.), 1989, Mar-31, Volume: 243, Issue:4899

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Fosca

1989