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foscarnet and AIDS-Related Opportunistic Infections

foscarnet has been researched along with AIDS-Related Opportunistic Infections in 243 studies

Foscarnet: An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
phosphonoformic acid : Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

AIDS-Related Opportunistic Infections: Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.

Research Excerpts

ExcerptRelevanceReference
"The clinical significance of cytomegalovirus (CMV) foscarnet resistance was studied in patients with acquired immunodeficiency syndrome and CMV retinitis."9.10Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. ( Chou, S; Crumpacker, C; Forman, MS; Jabs, DA; Lurain, NS; Martin, BK; Weinberg, A, 2003)
"The efficacy and toxicity of foscarnet cream for the treatment of mucocutaneous herpes simplex virus lesions or lesions that were clinically unresponsive to systemic acyclovir treatment (median, 30."9.09Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study. ( Bryson, Y; Grafford, K; Hardy, WD; Javaly, K; Kalayjian, R; Klein, T; Martin-Munley, S; Wohlfeiler, M, 1999)
"A randomized open-label phase 2 trial compared the virological and clinical effects on cytomegalovirus (CMV) infection of a 14-day course of intravenous foscarnet (100 mg/[kg x 12 h]) or no treatment in 42 HIV-infected patients with < 100 CD4 cells/mm3 and persistent asymptomatic CMV viremia."9.09Effect of a 14-day course of foscarnet on cytomegalovirus (CMV) blood markers in a randomized study of human immunodeficiency virus-infected patients with persistent CMV viremia. Agence National de Recherche du SIDA 023 Study Group. ( Aboulker, JP; Brun-Vézinet, F; Carrière, I; Fillet, AM; Gérard, L; Houhou, N; Leport, C; Ostinelli, J; Salmon-Céron, D; Vildé, JL, 1999)
"Patients with symptomatic gastrointestinal disease due to cytomegalovirus (CMV) were randomized to receive open-label ganciclovir (22) or foscarnet (26)."9.08Treatment of AIDS-associated gastrointestinal cytomegalovirus infection with foscarnet and ganciclovir: a randomized comparison. ( Benhamou, Y; Blanshard, C; Dohin, E; Gazzard, BG; Katlama, C; Lernestedt, JO, 1995)
"The use of foscarnet and ganciclovir as a combination treatment for cytomegalovirus retinitis is increasing because of limitations associated with single agent therapy."9.08Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis. ( Aweeka, FT; Emrick, L; Gambertoglio, JG; Jacobson, MA; Jayewardene, A; Kramer, F; Lizak, P; Polsky, B; Tong, W; van der Horst, C, 1995)
"Neutropenia was more common in patients assigned to ganciclovir than to foscarnet (34% vs 14%; P = ."9.08Morbidity and toxic effects associated with ganciclovir or foscarnet therapy in a randomized cytomegalovirus retinitis trial. Studies of ocular complications of AIDS Research Group, in collaboration with the AIDS Clinical Trials Group. ( , 1995)
"Four intravenous dosages of foscarnet given for 10 days were compared with no therapy in persons with AIDS who had asymptomatic cytomegalovirus (CMV) viremia."9.08Effect of foscarnet on quantities of cytomegalovirus and human immunodeficiency virus in blood of persons with AIDS. ( Acosta, EP; Balfour, HH; Boivin, G; Crumpacker, CS; Eaton, CA; Erice, A; Fletcher, CV; Henry, WK; Holm, MA; Martin-Munley, SS; Shepp, DH; Smith, SA, 1996)
"Although several uncontrolled studies have shown that the response rate to ganciclovir and foscarnet for all forms of cytomegalovirus (CMV) infection in immunocompromised patients is almost similar, to date, no controlled clinical trial has been specifically designed to compare these two agents in the treatment of CMV esophagitis."9.08Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group. ( Bianchi Porro, G; Parente, F, 1998)
"AIDS patients with newly diagnosed cytomegalovirus (CMV) retinitis who had just completed a 14-day course of ganciclovir induction therapy were randomly assigned to an alternating or concurrent combination regimen of chronic ganciclovir-foscarnet therapy for CMV retinitis."9.07Randomized phase I trial of two different combination foscarnet and ganciclovir chronic maintenance therapy regimens for AIDS patients with cytomegalovirus retinitis: AIDS clinical Trials Group Protocol 151. ( Bassiakos, Y; Geheb, H; Hooton, T; Jacobson, MA; Korvick, JA; Kramer, F; O'Donnell, JJ; Polsky, B; van der Horst, C; Walker, JD, 1994)
" The Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial is a multicenter, randomized, controlled, unmasked, clinical trial that compared ganciclovir and foscarnet as treatments for CMV retinitis in patients with AIDS."9.07Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. 4. Visual outcomes. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. ( , 1994)
"The efficacy and tolerance of high dose intravitreal foscarnet for cytomegalovirus retinitis in patients with AIDS was studied."9.07High dose intravitreal foscarnet in the treatment of cytomegalovirus retinitis in AIDS. ( Cano, J; Chipont, E; Diaz-Llopis, M; España, E; Menezo, JL; Muñoz, G; Navea, A; Romero, FJ, 1994)
"The aim of this study was to investigate peripheral blood polymorphonuclear leukocytes and, whenever possible, aqueous humor from 65 AIDS patients with ophthalmoscopically diagnosed human cytomegalovirus (HCMV) retinitis to determine (i) whether patients consistently carry viral DNA and (ii) to what extent foscarnet induction treatment decreases viral DNA levels."9.07Effect of foscarnet induction treatment on quantitation of human cytomegalovirus (HCMV) DNA in peripheral blood polymorphonuclear leukocytes and aqueous humor of AIDS patients with HCMV retinitis. The Italian Foscarnet Study Group. ( Baldanti, F; Furione, M; Gerna, G; Percivalle, E; Revello, MG; Sarasini, A; Zella, D; Zipeto, D, 1994)
"Thirty-two patients with AIDS and previously untreated cytomegalovirus retinitis completed an induction course of foscarnet, 60 mg/kg every 8 h for 14 days, had retinitis stabilize, and were then randomly assigned to receive foscarnet maintenance as either a 90- or 120-mg/kg/day infusion administered over 2 h."9.07A dose-ranging study of daily maintenance intravenous foscarnet therapy for cytomegalovirus retinitis in AIDS. ( Causey, D; Chown, M; Davis, R; Hardy, D; Heinemann, MH; Holland, GN; Jacobson, MA; Kuppermann, BD; O'Donnell, JJ; Polsky, B, 1993)
"Acyclovir-resistant herpes simplex virus (HSV) infection is common in immunocompromised patients, but the course of such infection is little known."7.80Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection. ( Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D, 2014)
"To describe the chronic use of high doses of intravitreal ganciclovir, in combination with foscarnet, for the treatment of cytomegalovirus retinitis."7.71High-dose intravitreal ganciclovir and foscarnet for cytomegalovirus retinitis. ( Chan, CC; Robinson, MR; Roy, CE; Velez, G; Whitcup, SM, 2001)
"Sequential herpes simplex virus (HSV) isolates from AIDS patients receiving foscarnet therapy were evaluated for susceptibility to adefovir."7.71Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy. ( Bestman-Smith, J; Boivin, G, 2002)
"Three human immunodeficiency virus-infected subjects with progressive cytomegalovirus (CMV) retinitis despite prolonged antiviral therapy had buffy coat CMV isolates that were resistant to both ganciclovir and foscarnet."7.70Mutation in region III of the DNA polymerase gene conferring foscarnet resistance in cytomegalovirus isolates from 3 subjects receiving prolonged antiviral therapy. ( Chou, S; Drew, WL; Gordon, SM; LaVoy, AG; Marousek, G; Miner, RC; Parenti, DM; Ross, JG, 1998)
" In this report we describe the effects of foscarnet on HHV-8 viremia in an HIV-infected patient with disseminated Kaposi s sarcoma and a presumably HHV-8 associated hemophagocytic syndrome."7.70Suppression of HHV-8 viremia by foscarnet in an HIV-infected patient with Kaposi's sarcoma and HHV-8 associated hemophagocytic syndrome. ( Fleckenstein, B; Harrer, T; Kalden, JR; Löw, P; Manger, B; Neipel, F; Rascu, A; Steininger, H, 1998)
"Herpes simplex virus (HSV) isolates were characterized from 8 AIDS patients in whom acyclovir and foscarnet therapy sequentially failed."7.70Characterization of the DNA polymerase and thymidine kinase genesof herpes simplex virus isolates from AIDS patients in whom acyclovirand foscarnet therapy sequentially failed. ( Boivin, G; Schmit, I, 1999)
"We report on a 28-year-old AIDS patient who developed a rapidly progressive glomerulonephritis while being treated with foscarnet for cytomegalovirus retinitis."7.69Crescentic glomerulonephritis and crystals within glomerular capillaries in an AIDS patient treated with foscarnet. ( Cahen, R; Cotte, L; Dijoud, F; François, B; Patricot, LM; Trepo, C; Trolliet, P, 1995)
"Foscarnet-resistant cytomegalovirus (ID50 > 300 microM) was isolated from two patients, one of whom was being treated with foscarnet."7.69Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir. ( Apuzzo, L; Charache, P; Dunn, JP; Forman, MS; Jabs, DA; MacCumber, MW, 1995)
"CMV esophagitis has a favorable response to induction ganciclovir therapy, and a long-term remission may occur after induction therapy alone."7.69Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome. ( Schwartz, DA; Straub, RF; Wilcox, CM, 1995)
" One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to acyclovir and was intolerant of foscarnet."7.69Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). ( Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G, 1994)
"These results suggest that while ganciclovir therapy may clinically stabilize CMV retinitis in patients with AIDS, it does not appear to prevent the development of, or be effective in the treatment of, CMV encephalitis."7.69The development of cytomegalovirus encephalitis in AIDS patients receiving ganciclovir. ( Berman, SM; Kim, RC, 1994)
"We treated seven patients (nine eyes) who had cytomegalovirus retinitis with daily intravenous ganciclovir plus foscarnet."7.69Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis. ( Murphy, R; Naughton, K; Weinberg, DV, 1994)
"Four human cytomegalovirus (HCMV) isolates from four different AIDS patients treated with both ganciclovir and foscarnet and not responding clinically to antiviral treatment, were studied in order to verify the occurrence of double resistance to both drugs, and to define whether single or multiple HCMV strains could be responsible for the double resistance."7.69Double resistance to ganciclovir and foscarnet of four human cytomegalovirus strains recovered from AIDS patients. ( Baldanti, F; Barbi, M; Brerra, R; Furione, M; Gerna, G; Percivalle, E; Sarasini, A, 1995)
"Three human cytomegalovirus (HCMV) strains (VR4760, VR4955, and VR5120) showing double resistance to ganciclovir (GCV) and foscarnet (PFA) were isolated from three patients with AIDS who underwent multiple sequential courses of therapy with GCV and PFA (A."7.69Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered f ( Baldanti, F; Biron, KK; Chou, S; Gerna, G; Sarasini, A; Silini, E; Stanat, SC; Underwood, MR, 1996)
"To determine the efficacy of combined ganciclovir and foscarnet intravitreal injections in controlling clinically resistant cytomegalovirus retinitis in a 37-year-old man with the acquired immunodeficiency syndrome who refused systemic therapy."7.69Treatment of clinically resistant cytomegalovirus retinitis with combined intravitreal injections of ganciclovir and foscarnet. ( Desatnik, HR; Foster, RE; Lowder, CY, 1996)
"Four human cytomegalovirus strains with double resistance to both ganciclovir and foscarnet were recovered from acquired immunodeficiency syndrome (AIDS) patients."7.69Four dually resistant human cytomegalovirus strains from AIDS patients: single mutations in UL97 and UL54 open reading frames are responsible for ganciclovir- and foscarnet-specific resistance, respectively. ( Baldanti, F; Barbi, M; Biron, KK; Gerna, G; Lazzarin, A; Sarasini, A; Silini, E, 1995)
" Administration of foscarnet during two years, recommended as suppressive therapy for a previous cytomegalovirus retinitis, might have caused a sustained reduction in plasma HIV-RNA, contributing to her long-term survival."7.69[Long term survival in an HIV-immunosuppressed patient treated with foscarnet]. ( Bravo, R; González-Lahoz, J; Mas, A; Moreno, V; Soriano, V, 1996)
"To assess the clinical response and patient tolerance to daily infusions of both ganciclovir sodium and foscarnet sodium for the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome."7.68Combination ganciclovir and foscarnet in the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. ( Flores-Aguilar, M; Freeman, WR; Kuppermann, BD; Quiceno, JI; Rickman, LS, 1993)
"Foscarnet (phosphonoformate) is a potent virustatic drug against herpes-like viruses and is widely used in the therapy of cytomegalovirus infections in immunosuppressed patients."7.68Foscarnet penetrates the blood-brain barrier: rationale for therapy of cytomegalovirus encephalitis. ( Brockmeyer, NH; Goos, M; Hengge, UR; Malessa, R; Ravens, U, 1993)
" There was no difference between the 2 groups in either serious adverse events or rise of creatinine to > or = 2."6.69Safety of oral versus intravenous hydration during induction therapy with intravenous foscarnet in AIDS patients with cytomegalovirus infections. ( Benson, P; Cheung, TW; Jayaweera, DT; Nahass, R; Olson, C; Pearce, D; Wool, GM, 2000)
"Patients were randomized to one of three therapeutic regimens: induction with foscarnet sodium at 90 mg/kg intravenously every 12 hours for 2 weeks, followed by maintenance at a dosage of 120 mg/kg per day (foscarnet group); induction with ganciclovir sodium at 5 mg/kg intravenously every 12 hours for 2 weeks followed by maintenance at 10 mg/kg per day (ganciclovir group); or continuation of previous maintenance therapy plus induction with the other drug (either ganciclovir or foscarnet) for 2 weeks followed by maintenance therapy with both drugs, ganciclovir sodium at 5 mg/kg per day and foscarnet sodium at 90 mg/kg per day (combination therapy group)."6.68Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The Cytomegalovirus Retreatment Trial. The Studies of Ocular Complications of AIDS Research Group in Collaboration ( , 1996)
"Retinal detachment was not associated with the type of anticytomegalovirus therapy (intravenous foscarnet or ganciclovir) to which the patient was assigned."6.68Rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis: the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS (SOCA) Research Group in Collaboration with the AIDS Clinical Trials Group ( , 1997)
" In both regimens the elimination half-life of foscarnet was 2-3 h."6.68Comparison of pharmacokinetics and dynamics of two dosage regimens of foscarnet in AIDS patients with Cytomegalovirus retinitis. ( Carosi, G; Castelli, F; Hedman, A; Suter, F; Tomasoni, L; Trespi, G; Zeroli, C, 1997)
"The DNA polymerase of human herpes viruses, including cytomegalovirus (CMV), and the reverse transcriptase of human immunodeficiency virus (HIV) are selectively inhibited in vitro by the pyrophosphate analogue foscarnet."6.17Foscarnet. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections. ( Bryson, HM; Wagstaff, AJ, 1994)
"A 41-year-old man with acquired immunodeficiency syndrome (AIDS) developed cytomegalovirus (CMV) retinitis."5.29[Foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome]. ( Fujino, Y; Kimura, S; Mochizuki, M; Mouri, H; Nagata, Y; Oka, S; Ono, A; Shimada, K, 1994)
" The dosing regimen for induction with the combined therapy was foscarnet (60 mg/kg every 8 hours) and ganciclovir (5 mg/kg daily for 3 weeks)."5.29Combined intravenous ganciclovir and foscarnet for children with recurrent cytomegalovirus retinitis. ( Lewis, LL; Mueller, BU; Nussenblatt, RB; Pizzo, PA; Walton, RC; Whitcup, SM, 1995)
"After withdrawal from maintenance treatment, a relapse of cytomegalovirus retinitis occurred, which was again successfully treated with ganciclovir."5.282.5 years survival with sequential ganciclovir/foscarnet treatment in a patient with acquired immune deficiency syndrome and cytomegalovirus retinitis. ( Geier, SA; Goebel, FD; Klauss, V; Kronawitter, U; Matuschke, A, 1992)
"The clinical significance of cytomegalovirus (CMV) foscarnet resistance was studied in patients with acquired immunodeficiency syndrome and CMV retinitis."5.10Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. ( Chou, S; Crumpacker, C; Forman, MS; Jabs, DA; Lurain, NS; Martin, BK; Weinberg, A, 2003)
"The efficacy and toxicity of foscarnet cream for the treatment of mucocutaneous herpes simplex virus lesions or lesions that were clinically unresponsive to systemic acyclovir treatment (median, 30."5.09Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study. ( Bryson, Y; Grafford, K; Hardy, WD; Javaly, K; Kalayjian, R; Klein, T; Martin-Munley, S; Wohlfeiler, M, 1999)
"To evaluate the efficacy and safety of the foscarnet-ganciclovir combination in induction therapy (IT) and maintenance therapy (MT) for cytomegalovirus (CMV) central neurological disorders in HIV-infected patients."5.09Induction and maintenance therapy of cytomegalovirus central nervous system infection in HIV-infected patients. ( Anduze-Faris, BM; Boukli, N; Caumes, E; Costagliola, D; Fillet, AM; Gasnault, J; Gozlan, J; Katlama, C; Lancar, R; Leport, C; Livartowsky, J; Matheron, S; Salmon, D, 2000)
"A randomized open-label phase 2 trial compared the virological and clinical effects on cytomegalovirus (CMV) infection of a 14-day course of intravenous foscarnet (100 mg/[kg x 12 h]) or no treatment in 42 HIV-infected patients with < 100 CD4 cells/mm3 and persistent asymptomatic CMV viremia."5.09Effect of a 14-day course of foscarnet on cytomegalovirus (CMV) blood markers in a randomized study of human immunodeficiency virus-infected patients with persistent CMV viremia. Agence National de Recherche du SIDA 023 Study Group. ( Aboulker, JP; Brun-Vézinet, F; Carrière, I; Fillet, AM; Gérard, L; Houhou, N; Leport, C; Ostinelli, J; Salmon-Céron, D; Vildé, JL, 1999)
"Patients with symptomatic gastrointestinal disease due to cytomegalovirus (CMV) were randomized to receive open-label ganciclovir (22) or foscarnet (26)."5.08Treatment of AIDS-associated gastrointestinal cytomegalovirus infection with foscarnet and ganciclovir: a randomized comparison. ( Benhamou, Y; Blanshard, C; Dohin, E; Gazzard, BG; Katlama, C; Lernestedt, JO, 1995)
"The use of foscarnet and ganciclovir as a combination treatment for cytomegalovirus retinitis is increasing because of limitations associated with single agent therapy."5.08Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis. ( Aweeka, FT; Emrick, L; Gambertoglio, JG; Jacobson, MA; Jayewardene, A; Kramer, F; Lizak, P; Polsky, B; Tong, W; van der Horst, C, 1995)
"Foscarnet inhibits human immunodeficiency virus (HIV) replication in vitro and decreases p24 antigenemia in patients with cytomegalovirus (CMV) retinitis."5.08Foscarnet decreases human immunodeficiency virus RNA. ( Furrer, H; Hirschel, B; Kaiser, L; Olmari, M; Perrin, L; Von Overbeck, J; Yerly, S, 1995)
"Neutropenia was more common in patients assigned to ganciclovir than to foscarnet (34% vs 14%; P = ."5.08Morbidity and toxic effects associated with ganciclovir or foscarnet therapy in a randomized cytomegalovirus retinitis trial. Studies of ocular complications of AIDS Research Group, in collaboration with the AIDS Clinical Trials Group. ( , 1995)
"Twenty-six subjects enrolled in a randomized trial that compared foscarnet and ganciclovir for the treatment of cytomegalovirus retinitis."5.08Measuring visual function and quality of life in patients with cytomegalovirus retinitis. Development of a questionnaire. Studies of Ocular Complication of AIDS Research Group. ( Coleson, LC; Holbrook, J; Jabs, DA; Wu, AW, 1996)
"Four intravenous dosages of foscarnet given for 10 days were compared with no therapy in persons with AIDS who had asymptomatic cytomegalovirus (CMV) viremia."5.08Effect of foscarnet on quantities of cytomegalovirus and human immunodeficiency virus in blood of persons with AIDS. ( Acosta, EP; Balfour, HH; Boivin, G; Crumpacker, CS; Eaton, CA; Erice, A; Fletcher, CV; Henry, WK; Holm, MA; Martin-Munley, SS; Shepp, DH; Smith, SA, 1996)
"Although several uncontrolled studies have shown that the response rate to ganciclovir and foscarnet for all forms of cytomegalovirus (CMV) infection in immunocompromised patients is almost similar, to date, no controlled clinical trial has been specifically designed to compare these two agents in the treatment of CMV esophagitis."5.08Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group. ( Bianchi Porro, G; Parente, F, 1998)
"To evaluate the efficacy of ganciclovir, foscarnet, or the combination of both for the treatment of cytomegalovirus polyradiculomyelopathy (CMV-PRAM), we reviewed the records of seven patients with AIDS, diagnosed with CMV-PRAM."5.08[Cytomegalovirus polyradiculomyelopathy in AIDS]. ( Cassetti, LI; Espinoza, L; Hansman-Whiteman, ML; Jayaweera, DT; Lopardo, GD; Scerpella, EG, 1998)
"AIDS patients with newly diagnosed cytomegalovirus (CMV) retinitis who had just completed a 14-day course of ganciclovir induction therapy were randomly assigned to an alternating or concurrent combination regimen of chronic ganciclovir-foscarnet therapy for CMV retinitis."5.07Randomized phase I trial of two different combination foscarnet and ganciclovir chronic maintenance therapy regimens for AIDS patients with cytomegalovirus retinitis: AIDS clinical Trials Group Protocol 151. ( Bassiakos, Y; Geheb, H; Hooton, T; Jacobson, MA; Korvick, JA; Kramer, F; O'Donnell, JJ; Polsky, B; van der Horst, C; Walker, JD, 1994)
" The Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial is a multicenter, randomized, controlled, unmasked, clinical trial that compared ganciclovir and foscarnet as treatments for CMV retinitis in patients with AIDS."5.07Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. 4. Visual outcomes. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. ( , 1994)
"The efficacy and tolerance of high dose intravitreal foscarnet for cytomegalovirus retinitis in patients with AIDS was studied."5.07High dose intravitreal foscarnet in the treatment of cytomegalovirus retinitis in AIDS. ( Cano, J; Chipont, E; Diaz-Llopis, M; España, E; Menezo, JL; Muñoz, G; Navea, A; Romero, FJ, 1994)
"The aim of this study was to investigate peripheral blood polymorphonuclear leukocytes and, whenever possible, aqueous humor from 65 AIDS patients with ophthalmoscopically diagnosed human cytomegalovirus (HCMV) retinitis to determine (i) whether patients consistently carry viral DNA and (ii) to what extent foscarnet induction treatment decreases viral DNA levels."5.07Effect of foscarnet induction treatment on quantitation of human cytomegalovirus (HCMV) DNA in peripheral blood polymorphonuclear leukocytes and aqueous humor of AIDS patients with HCMV retinitis. The Italian Foscarnet Study Group. ( Baldanti, F; Furione, M; Gerna, G; Percivalle, E; Revello, MG; Sarasini, A; Zella, D; Zipeto, D, 1994)
"Thirty-two patients with AIDS and previously untreated cytomegalovirus retinitis completed an induction course of foscarnet, 60 mg/kg every 8 h for 14 days, had retinitis stabilize, and were then randomly assigned to receive foscarnet maintenance as either a 90- or 120-mg/kg/day infusion administered over 2 h."5.07A dose-ranging study of daily maintenance intravenous foscarnet therapy for cytomegalovirus retinitis in AIDS. ( Causey, D; Chown, M; Davis, R; Hardy, D; Heinemann, MH; Holland, GN; Jacobson, MA; Kuppermann, BD; O'Donnell, JJ; Polsky, B, 1993)
" Herpes virus type 1 and rarely type 2 may lead to painful and resistant oral ulcers, and systemic treatment with acyclovir, valaciclovir or famciclovir is indicated."4.79Viral lesions of the mouth in HIV-infected patients. ( Itin, PH; Lautenschlager, S, 1997)
"The nucleoside analog acyclovir is remarkably effective and selective in herpes simplex virus (HSF) infections."4.78[Resistance of herpes simplex viruses to antiviral drugs]. ( Bianchi, A; Scieux, C, 1993)
"Acyclovir-resistant herpes simplex virus (HSV) infection is common in immunocompromised patients, but the course of such infection is little known."3.80Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection. ( Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D, 2014)
"To describe the chronic use of high doses of intravitreal ganciclovir, in combination with foscarnet, for the treatment of cytomegalovirus retinitis."3.71High-dose intravitreal ganciclovir and foscarnet for cytomegalovirus retinitis. ( Chan, CC; Robinson, MR; Roy, CE; Velez, G; Whitcup, SM, 2001)
"To determine the prevalence of the in vitro resistance rate of cytomegalovirus (CMV) to gancyclovir (GCV) and foscarnet (FOS) among patients with AIDS and chorioretinitis."3.71[Cytomegalovirus sensitivity to anti-retroviral agents in patients infected with the human immunodeficiency virus with chorioretinitis in Spain]. ( Cañizares, MA; Casado, JL; González, J; Guerrero, A; Losada, I; Pérez-Elías, MJ; Rubio, R, 2001)
"Sequential herpes simplex virus (HSV) isolates from AIDS patients receiving foscarnet therapy were evaluated for susceptibility to adefovir."3.71Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy. ( Bestman-Smith, J; Boivin, G, 2002)
"Three human immunodeficiency virus-infected subjects with progressive cytomegalovirus (CMV) retinitis despite prolonged antiviral therapy had buffy coat CMV isolates that were resistant to both ganciclovir and foscarnet."3.70Mutation in region III of the DNA polymerase gene conferring foscarnet resistance in cytomegalovirus isolates from 3 subjects receiving prolonged antiviral therapy. ( Chou, S; Drew, WL; Gordon, SM; LaVoy, AG; Marousek, G; Miner, RC; Parenti, DM; Ross, JG, 1998)
"Three acquired immune deficiency syndrome patients given foscarnet to treat cytomegalovirus retinitis developed renal failure with crystal deposits within the renal glomeruli."3.70Identification of crystals in kidneys of AIDS patients treated with foscarnet. ( Beaufils, H; Daudon, M; Jouanneau, C; Katlama, C; Lacour, B; Maurice-Estepa, L; Sazdovitch, V, 1998)
" In this report we describe the effects of foscarnet on HHV-8 viremia in an HIV-infected patient with disseminated Kaposi s sarcoma and a presumably HHV-8 associated hemophagocytic syndrome."3.70Suppression of HHV-8 viremia by foscarnet in an HIV-infected patient with Kaposi's sarcoma and HHV-8 associated hemophagocytic syndrome. ( Fleckenstein, B; Harrer, T; Kalden, JR; Löw, P; Manger, B; Neipel, F; Rascu, A; Steininger, H, 1998)
"Herpes simplex virus (HSV) isolates were characterized from 8 AIDS patients in whom acyclovir and foscarnet therapy sequentially failed."3.70Characterization of the DNA polymerase and thymidine kinase genesof herpes simplex virus isolates from AIDS patients in whom acyclovirand foscarnet therapy sequentially failed. ( Boivin, G; Schmit, I, 1999)
"We report on a 28-year-old AIDS patient who developed a rapidly progressive glomerulonephritis while being treated with foscarnet for cytomegalovirus retinitis."3.69Crescentic glomerulonephritis and crystals within glomerular capillaries in an AIDS patient treated with foscarnet. ( Cahen, R; Cotte, L; Dijoud, F; François, B; Patricot, LM; Trepo, C; Trolliet, P, 1995)
" We attempted to detect cytomegalovirus DNA in 19 vitreous samples from patients with the acquired immunodeficiency syndrome (AIDS) who had untreated cytomegalovirus retinitis and in 40 vitreous samples from patients with AIDS who had been treated with systemic ganciclovir or foscarnet, or both."3.69A sensitive and specific polymerase chain reaction-based assay for the diagnosis of cytomegalovirus retinitis. ( Ai, E; Irvine, AR; Kuppermann, BD; Luckie, AP; Margolis, TP; McCann, JD; Schwartz, DM; Wong, MG, 1995)
"Foscarnet-resistant cytomegalovirus (ID50 > 300 microM) was isolated from two patients, one of whom was being treated with foscarnet."3.69Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir. ( Apuzzo, L; Charache, P; Dunn, JP; Forman, MS; Jabs, DA; MacCumber, MW, 1995)
"CMV esophagitis has a favorable response to induction ganciclovir therapy, and a long-term remission may occur after induction therapy alone."3.69Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome. ( Schwartz, DA; Straub, RF; Wilcox, CM, 1995)
" One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to acyclovir and was intolerant of foscarnet."3.69Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). ( Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G, 1994)
"These results suggest that while ganciclovir therapy may clinically stabilize CMV retinitis in patients with AIDS, it does not appear to prevent the development of, or be effective in the treatment of, CMV encephalitis."3.69The development of cytomegalovirus encephalitis in AIDS patients receiving ganciclovir. ( Berman, SM; Kim, RC, 1994)
"We treated seven patients (nine eyes) who had cytomegalovirus retinitis with daily intravenous ganciclovir plus foscarnet."3.69Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis. ( Murphy, R; Naughton, K; Weinberg, DV, 1994)
"Four human cytomegalovirus (HCMV) isolates from four different AIDS patients treated with both ganciclovir and foscarnet and not responding clinically to antiviral treatment, were studied in order to verify the occurrence of double resistance to both drugs, and to define whether single or multiple HCMV strains could be responsible for the double resistance."3.69Double resistance to ganciclovir and foscarnet of four human cytomegalovirus strains recovered from AIDS patients. ( Baldanti, F; Barbi, M; Brerra, R; Furione, M; Gerna, G; Percivalle, E; Sarasini, A, 1995)
"Three human cytomegalovirus (HCMV) strains (VR4760, VR4955, and VR5120) showing double resistance to ganciclovir (GCV) and foscarnet (PFA) were isolated from three patients with AIDS who underwent multiple sequential courses of therapy with GCV and PFA (A."3.69Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered f ( Baldanti, F; Biron, KK; Chou, S; Gerna, G; Sarasini, A; Silini, E; Stanat, SC; Underwood, MR, 1996)
"To determine the efficacy of combined ganciclovir and foscarnet intravitreal injections in controlling clinically resistant cytomegalovirus retinitis in a 37-year-old man with the acquired immunodeficiency syndrome who refused systemic therapy."3.69Treatment of clinically resistant cytomegalovirus retinitis with combined intravitreal injections of ganciclovir and foscarnet. ( Desatnik, HR; Foster, RE; Lowder, CY, 1996)
"To determine the prevalence of cytomegalovirus (CMV) isolates resistant to ganciclovir sodium or foscarnet sodium at the time of diagnosis of CMV retinitis, prior to the initiation of therapy."3.69Cytomegalovirus retinitis and viral resistance. Prevalence of resistance at diagnosis, 1994. Cytomegalovirus Retinitis and Viral Resistance Study Group. ( Bressler, N; Charache, P; Dunn, JP; Enger, C; Forman, M; Jabs, DA, 1996)
"Four human cytomegalovirus strains with double resistance to both ganciclovir and foscarnet were recovered from acquired immunodeficiency syndrome (AIDS) patients."3.69Four dually resistant human cytomegalovirus strains from AIDS patients: single mutations in UL97 and UL54 open reading frames are responsible for ganciclovir- and foscarnet-specific resistance, respectively. ( Baldanti, F; Barbi, M; Biron, KK; Gerna, G; Lazzarin, A; Sarasini, A; Silini, E, 1995)
"We describe a 28-year-old HIV-infected woman with AIDS, defined by cerebral toxoplasmosis and a CD4-count of less than 10 x 10(6) cells/I, who, after several eruptions of genital herpes and typical dermatomal herpes zoster, all successfully treated with acyclovir, developed chronic cutaneous ulcerating lesions on a finger and on the tibia."3.69Chronic ulcerating acyclovir-resistant varicella zoster lesions in an AIDS patient. ( Bernhard, P; Obel, N, 1995)
" Administration of foscarnet during two years, recommended as suppressive therapy for a previous cytomegalovirus retinitis, might have caused a sustained reduction in plasma HIV-RNA, contributing to her long-term survival."3.69[Long term survival in an HIV-immunosuppressed patient treated with foscarnet]. ( Bravo, R; González-Lahoz, J; Mas, A; Moreno, V; Soriano, V, 1996)
"Antiviral susceptibilities to ganciclovir, foscarnet, and cidofovir and sequencing of UL97 and DNA polymerase were done on 23 cytomegalovirus (CMV) isolates from 10 immunocompromised persons with end-organ CMV disease who were treated with ganciclovir alone or ganciclovir followed by foscarnet."3.69Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients. ( Balfour, HH; Boivin, G; Chou, S; Erice, A; Gil-Roda, C; Hanson, MN; Pérez, JL; Sannerud, KJ, 1997)
"In a human immunodeficiency virus-infected subject, cytomegalovirus (CMV) isolated 9 months after the patient began oral ganciclovir prophylaxis was resistant to ganciclovir and cidofovir and contained mutations in both UL97 and Pol coding regions."3.69Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. ( Chou, S; Drew, WL; Follansbee, SE; Guentzel, S; Lalezari, JP; Marousek, G; Miner, RC; Poscher, ME, 1997)
"In order to assess the value of quantitative measurement of cytomegalovirus (CMV) antigenaemia as a marker for the guidance of antiviral chemotherapy in the AIDS setting, 33 patients with CMV complications and showing at least 20 pp65-positive polymorphonuclear leucocytes per 2 x 10(5) cells, received either ganciclovir or foscarnet as induction and maintenance therapy."3.69Quantitative cytomegalovirus (CMV) antigenaemia during antiviral treatment of AIDS-related CMV disease. ( Chiodo, F; Coronado, OV; Dal Monte, P; Lazzarotto, T; Manfredi, R; Mastroianni, A; Spezzacatena, P, 1997)
") are discussed, as is the use of imiquimod treatment for genital warts."3.69International Congress on Chemotherapy. ( Smart, T, 1995)
"Foscavir (foscarnet sodium) has been approved by the Food and Drug Administration (FDA) for use in combination with Cytovene (intravenous ganciclovir) for the treatment of recurrent AIDS-related cytomegalovirus retinitis that has been treated previously with either drug alone."3.69Foscavir receives new indication. ( , 1997)
"To assess the clinical response and patient tolerance to daily infusions of both ganciclovir sodium and foscarnet sodium for the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome."3.68Combination ganciclovir and foscarnet in the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. ( Flores-Aguilar, M; Freeman, WR; Kuppermann, BD; Quiceno, JI; Rickman, LS, 1993)
"Foscarnet (phosphonoformate) is a potent virustatic drug against herpes-like viruses and is widely used in the therapy of cytomegalovirus infections in immunosuppressed patients."3.68Foscarnet penetrates the blood-brain barrier: rationale for therapy of cytomegalovirus encephalitis. ( Brockmeyer, NH; Goos, M; Hengge, UR; Malessa, R; Ravens, U, 1993)
"Sequential visual field testing is an extremely helpful adjunct to ophthalmoscopy and fundus photography in the management of cytomegalovirus (CMV) retinitis with the antiviral agents ganciclovir or foscarnet in patients with the acquired immune deficiency syndrome (AIDS)."3.68Visual field testing in the management of cytomegalovirus retinitis. ( Bachman, DM; Bruni, LM; DiGioia, RA; Harris, PJ; McMackin, CM; Pistole, MC; Thomas, RM; Ward, DJ, 1992)
"ACTG 266 was designed as a randomized study to evaluate two doses of the human monoclonal antibody directed against CMV gH (MSL-109) versus placebo, each in combination with standard antiviral therapy for the treatment of newly diagnosed Cytomegalovirus (CMV) retinitis in AIDS patients."2.71A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus re ( Alston, B; Asmuth, DM; Aweeka, F; Borucki, MJ; Caliendo, A; Gnann, J; Hirsch, MS; Hubbard, L; Nadler, PI; Nevin, TT; Nokta, M; Owens, S; Pollard, RB; Sattler, F; Spritzler, J; Waterman, K, 2004)
" There was no difference between the 2 groups in either serious adverse events or rise of creatinine to > or = 2."2.69Safety of oral versus intravenous hydration during induction therapy with intravenous foscarnet in AIDS patients with cytomegalovirus infections. ( Benson, P; Cheung, TW; Jayaweera, DT; Nahass, R; Olson, C; Pearce, D; Wool, GM, 2000)
"Patients were randomized to one of three therapeutic regimens: induction with foscarnet sodium at 90 mg/kg intravenously every 12 hours for 2 weeks, followed by maintenance at a dosage of 120 mg/kg per day (foscarnet group); induction with ganciclovir sodium at 5 mg/kg intravenously every 12 hours for 2 weeks followed by maintenance at 10 mg/kg per day (ganciclovir group); or continuation of previous maintenance therapy plus induction with the other drug (either ganciclovir or foscarnet) for 2 weeks followed by maintenance therapy with both drugs, ganciclovir sodium at 5 mg/kg per day and foscarnet sodium at 90 mg/kg per day (combination therapy group)."2.68Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The Cytomegalovirus Retreatment Trial. The Studies of Ocular Complications of AIDS Research Group in Collaboration ( , 1996)
" Adverse events resulted in discontinuance of medication in the case of one patient."2.68Treatment of gastrointestinal cytomegalovirus infection with twice-daily foscarnet: a pilot study of safety, efficacy, and pharmacokinetics in patients with AIDS. ( Dieterich, DT; Faust, MJ; Johnson, J; Lew, EA; Martin-Munley, S; Nix, D; Poles, MA, 1997)
"Retinal detachment was not associated with the type of anticytomegalovirus therapy (intravenous foscarnet or ganciclovir) to which the patient was assigned."2.68Rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis: the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS (SOCA) Research Group in Collaboration with the AIDS Clinical Trials Group ( , 1997)
" In both regimens the elimination half-life of foscarnet was 2-3 h."2.68Comparison of pharmacokinetics and dynamics of two dosage regimens of foscarnet in AIDS patients with Cytomegalovirus retinitis. ( Carosi, G; Castelli, F; Hedman, A; Suter, F; Tomasoni, L; Trespi, G; Zeroli, C, 1997)
"There are no published data on varicella in HIV-infected adults, however, probably because most adults have already experienced varicella prior to HIV infection."2.41Prevention and treatment of VZV infections in patients with HIV. ( Gershon, AA, 2001)
"The first is the acute retinal necrosis syndrome, which also may be seen in immunocompetent hosts."2.41Aseptic meningitis and optic neuritis preceding varicella-zoster progressive outer retinal necrosis in a patient with AIDS. ( Bellehemeur, T; DiazGranados, C; Franco-Paredes, C; Merchant, A; Rimland, D; Sanghi, P, 2002)
" New modes of treatment have attempted to prolong intervals between dosing and reduce drug-related toxicity in an effort to improve quality of life."2.40Pharmacologic management of cytomegalovirus retinitis: review of current and future therapeutic modalities. ( Bright, DC, 1997)
" Their adverse effects mostly involve bone marrow depression (e."2.39Adverse effects and drug interactions of clinical importance with antiviral drugs. ( Morris, DJ, 1994)
"The median number of recurrences up to the observation of foveal-sparing retinitis was two (range one to eight), and five patients had active CMV retinitis despite treatment for at least two continuous months."2.39A foveal-sparing pattern of cytomegalovirus retinitis in the acquired immunodeficiency syndrome. ( Ai, E; Luckie, AP, 1996)
"The incidence of cytomegalovirus retinitis has decreased significantly since the advent of antiretroviral therapy."1.40Management of ganciclovir-resistant cytomegalovirus retinitis in HIV infection in the era of antiretroviral therapy. ( Acheson, RW; Adler, H; Brannigan, ET; De Gascun, CF; Duffy, M; Keegan, DJ; Lambert, JS; McSweeney, F, 2014)
"The foscarnet resistance was associated with an S725G mutation in a conserved region (region II) of the herpesvirus DNA pol gene."1.31Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient. ( Birch, C; Chibo, D; Doherty, R; Mijch, A, 2002)
"In one eye, the cystoid macular edema was worsened by formation of a dense juxtafoveal epiretinal membrane."1.30Cystoid macular edema associated with cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. ( Cunningham, ET; Jones, MR; Schwartz, D; Silverstein, BE; Smith, JH; Sykes, SO, 1998)
"A mild recurrence developed in one eye when ganciclovir and foscarnet were both tapered to a single daily dose."1.30The progressive outer retinal necrosis syndrome: successful treatment with combination antiviral therapy. ( Ciulla, TA; Duker, JS; Morley, MG; Rutledge, BK, 1998)
"The initial and maintenance treatment of CMV retinitis must be individualized based on the characteristics of the lesions, including location and extent, specific patient factors, and characteristics of available therapies among others."1.30Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA. ( Benson, CA; Deutsch, TA; Dieterich, DT; Drew, WL; Feinberg, J; Friedberg, DN; Griffiths, PD; Hardy, WD; Holland, GN; Jabs, DA; Jacobson, MA; Kessler, HA; Polis, MA; Powderly, WG; Spector, SA; Walmsley, S; Whitley, RJ, 1998)
"The acute lumbosacral polyradiculomyelitis (ALP) in patients with AIDS is a well defined nosologic entity and classically associated to CMV infection."1.30[Lumbosacral polyradiculomyelitis caused by herpes simplex virus (HSV) in a patient with AIDS]. ( Correa-Nazco, VJ; González, M; Laynez, P; Linares, M; Martínez, A; Miguélez, M, 1999)
"CMV viremia was present in 4 patients."1.29Cytomegalovirus ventriculoencephalitis in AIDS patients. ( Fernandez-Viladrich, P; Ferrer, I; Gudiol, F; Perez, JL; Podzamczer, D; Reñe, R; Salazar, A; Santin, M, 1995)
"Among the 861 patients with AIDS treated in our unit from 1991 to 1993, 7 cases involving cytomegalovirus infection of the conus medullaris and/or the cauda equina were studied retrospectively."1.29[Lesions of the conus medullaris and the cauda equina caused by cytomegalovirus in HIV infection. 7 cases]. ( el Amrani, M; Girard, PM; Gozlan, J; Jacomet, C; Lebrette, MG; Monfort, L; Rozenbaum, W, 1995)
"A 41-year-old man with acquired immunodeficiency syndrome (AIDS) developed cytomegalovirus (CMV) retinitis."1.29[Foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome]. ( Fujino, Y; Kimura, S; Mochizuki, M; Mouri, H; Nagata, Y; Oka, S; Ono, A; Shimada, K, 1994)
"Retinal detachment was seen in 14 patients (relative frequency, 19."1.29Retinal detachment in patients with acquired immunodeficiency syndrome. ( Bogner, JR; Geier, SA; Goebel, FD; Klauss, V; Sadri, I; Schmidt-Kittler, H, 1994)
"In four of the five patients, recurrences were temporally associated with a reduction in the amount of antiviral medication being received."1.29Recurrence of presumed varicella-zoster virus retinopathy in patients with acquired immunodeficiency syndrome. ( Engstrom, RE; Holland, GN; Johnston, WH; Rimmer, S, 1993)
"Furthermore, this patient had sclerosing cholangitis of the intra- and extrahepatic bile ducts as well as papillary stenosis."1.29Acalculous cholecystitis associated with cytomegalovirus and sclerosing cholangitis in a patient with acquired immunodeficiency syndrome. ( Baron, DL; Brunton, JL; Gallinger, S; Keshavjee, SH; Magee, LA; Mullen, BJ, 1993)
"Effective diagnosis and treatment of cytomegalovirus infection of the nervous system in AIDS patients has been limited by a lack of sensitive diagnostic measures."1.29Prognosis and response to therapy of cytomegalovirus encephalitis and meningomyelitis in AIDS. ( Cohen, BA, 1996)
"Among the atypical forms of chronic varicella, this eruption appears to be unique."1.29Chronic varicella presenting as disseminated pinpoint-sized papules in a man infected with the human immunodeficiency virus. ( Castanet, J; Durant, J; Lacour, JP; Ortonne, JP; Perrin, C; Rodot, S; Van Elslande, L, 1996)
" The dosing regimen for induction with the combined therapy was foscarnet (60 mg/kg every 8 hours) and ganciclovir (5 mg/kg daily for 3 weeks)."1.29Combined intravenous ganciclovir and foscarnet for children with recurrent cytomegalovirus retinitis. ( Lewis, LL; Mueller, BU; Nussenblatt, RB; Pizzo, PA; Walton, RC; Whitcup, SM, 1995)
"The P & T Committee at Trinity Lutheran Hospital, a 320-bed, community/teaching hospital in Kansas City, MO, has developed dosing and monitoring guidelines for foscarnet sodium (Foscavir) and trimetrexate glucuronate (Neutrexin)--two drugs used to treat patients with opportunistic infections associated with the human immunodeficiency virus (HIV)."1.29Dosing guidelines for foscarnet and trimetrexate. ( Chase, K; Henry, RB; O'Connor, MC; Wooten, JM, 1995)
"After withdrawal from maintenance treatment, a relapse of cytomegalovirus retinitis occurred, which was again successfully treated with ganciclovir."1.282.5 years survival with sequential ganciclovir/foscarnet treatment in a patient with acquired immune deficiency syndrome and cytomegalovirus retinitis. ( Geier, SA; Goebel, FD; Klauss, V; Kronawitter, U; Matuschke, A, 1992)
"Forty-four percent remained free of recurrences until they died (for up to 15 months); 56% had 1 to 4 recurrences, altogether 35 episodes, of which 14 occurred after withdrawal of therapy."1.28[Cytomegalovirus retinitis in AIDS. Effectiveness and complications of long-term therapy]. ( Fabricius, EM; Popescu, M; Schmitz, K, 1992)

Research

Studies (243)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's205 (84.36)18.2507
2000's32 (13.17)29.6817
2010's6 (2.47)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adler, H1
De Gascun, CF1
McSweeney, F1
Acheson, RW1
Brannigan, ET1
Duffy, M1
Keegan, DJ1
Lambert, JS1
Seang, S1
Boutolleau, D1
Burrel, S1
Regnier, S1
Epelboin, L1
Voujon, D1
Valantin, MA1
Katlama, C7
Agut, H2
Caumes, E4
Churgin, D1
Relhan, N1
Davis, JL2
Albini, TA1
Timperley, A1
Taha, H1
Das, S1
Yudin, MH1
Kaul, R1
Sohal, A1
Riordan, A1
Mallewa, M1
Solomon, T1
Kneen, R1
Jabs, DA12
Martin, BK3
Forman, MS3
Di Lucca-Christment, J1
Jacobelli, S1
Gressier, L1
Plantier, F1
Laude, H1
Rozenberg, F1
Rosenberg, F1
Morini, JP1
Dallot, A1
Avril, MF1
Dupin, N1
Kimberlin, DW1
Scott, IU1
Luu, KM1
Chibo, D1
Mijch, A1
Doherty, R1
Birch, C1
Leśnikowski, ZJ1
Paradowska, E1
Przepiórkiewicz, M1
Olejniczak, A1
Emery, VC1
Holbrook, JT3
Weinberg, DV4
Lewis, RA1
Davis, MD2
Friedberg, D1
Weinberg, A1
Chou, S5
Lurain, NS1
Crumpacker, C1
Rapp, P1
Pilon, F1
Chiambaretta, F1
Ménérath, JM1
Jacomet, C2
Borucki, MJ1
Spritzler, J1
Asmuth, DM1
Gnann, J1
Hirsch, MS1
Nokta, M1
Aweeka, F1
Nadler, PI1
Sattler, F1
Alston, B1
Nevin, TT1
Owens, S2
Waterman, K1
Hubbard, L2
Caliendo, A1
Pollard, RB1
Demols, P1
Claes, CA1
Farber, CM1
Rasquin, F1
Nakamoto, BK1
Dorotheo, EU1
Biousse, V1
Tang, RA1
Schiffman, JS1
Newman, NJ1
Ausayakhun, S1
Watananikorn, S1
Ngamtiphakorn, S1
Prasitsilp, J1
Kitajima, N1
Luckie, AP3
Wagstaff, AJ1
Bryson, HM1
Trolliet, P1
Dijoud, F1
Cotte, L1
Cahen, R1
François, B1
Trepo, C1
Patricot, LM1
McCann, JD1
Margolis, TP1
Wong, MG1
Kuppermann, BD5
Schwartz, DM1
Irvine, AR2
Ai, E2
Blanshard, C1
Benhamou, Y1
Dohin, E1
Lernestedt, JO2
Gazzard, BG4
Costagliola, D2
Mary-Krause, M1
Salazar, A1
Podzamczer, D1
Reñe, R1
Santin, M1
Perez, JL2
Ferrer, I1
Fernandez-Viladrich, P1
Gudiol, F1
Engstrom, RE2
Holland, GN6
Thimons, JJ1
Aweeka, FT1
Gambertoglio, JG2
Kramer, F2
van der Horst, C2
Polsky, B3
Jayewardene, A1
Lizak, P1
Emrick, L1
Tong, W1
Jacobson, MA11
Polis, MA2
Masur, H1
Dunn, JP3
MacCumber, MW1
Charache, P2
Apuzzo, L1
Levinson, RD1
Raffi, F1
Lebrette, MG1
el Amrani, M1
Monfort, L1
Gozlan, J2
Girard, PM1
Rozenbaum, W1
Aguirrebengoa, K1
González, R1
Oñate, J1
Ibáñez de Maeztu, JC1
Ruiz-Irastorza, G1
Montejo, M1
Kaiser, L1
Perrin, L1
Hirschel, B1
Furrer, H1
Von Overbeck, J1
Olmari, M1
Yerly, S1
Balfour, HH3
Wilcox, CM1
Straub, RF1
Schwartz, DA1
Jones, JL2
Hanson, DL2
Chu, SY1
Ward, JW1
Jaffe, HW2
Colucciello, M1
Moyle, G2
Hamprecht, K1
Jahn, G1
Albrecht, H1
Stellbrink, HJ1
Brewster, D1
Greten, H1
Colebunders, R1
Van den Abbeele, K1
Fleerackers, Y1
Bols, K1
Lachenal, M1
Van Damme, L1
Wulfsohn, M1
Feinberg, JE1
Davis, R2
Power, M1
Causey, D2
Heath-Chiozzi, ME1
Murphy, RL1
Cheung, TW3
Bassiakos, Y1
Hooton, T1
Geheb, H1
O'Donnell, JJ2
Walker, JD1
Korvick, JA1
Morris, DJ1
Stamminger, T1
Fleckenstein, B2
Snoeck, R1
Andrei, G1
Gérard, M1
Silverman, A1
Hedderman, A1
Balzarini, J1
Sadzot-Delvaux, C1
Tricot, G1
Clumeck, N1
De Clercq, E1
Karmochkine, M1
Molina, JM1
Scieux, C2
Welker, Y1
Morinet, F1
Decazes, JM1
Lagrange, P1
Schnell, L1
Modai, J1
Nagata, Y1
Fujino, Y1
Ono, A1
Mochizuki, M1
Mouri, H1
Oka, S1
Kimura, S1
Shimada, K1
Poles, MA4
McMeeking, AA1
Scholes, JV1
Dieterich, DT5
Domingo, P1
Puig, M1
Iranzo, A1
Lopez-Contreras, J1
Ris, J1
Freeman, WR6
Stanley, HD1
Charlebois, E1
Harb, G1
Lieberman, RM1
Orellana, J1
Melton, RC1
Diaz-Llopis, M1
España, E1
Muñoz, G1
Navea, A1
Chipont, E1
Cano, J1
Menezo, JL1
Romero, FJ1
Gerna, G7
Baldanti, F6
Sarasini, A6
Furione, M3
Percivalle, E4
Revello, MG3
Zipeto, D1
Zella, D2
Geier, SA3
Klauss, V2
Bogner, JR3
Schmidt-Kittler, H1
Sadri, I2
Goebel, FD4
Peters, M2
Schürmann, D3
Bergmann, F2
Grünewald, T1
Timm, H2
Pohle, HD2
Ruf, B2
Berman, SM1
Kim, RC1
Murphy, R2
Naughton, K2
Flores-Aguilar, M3
Quiceno, JI4
Rickman, LS1
Ricart Olmos, C1
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Klein, T1
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Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component[NCT00000665]240 participants InterventionalCompleted
A Phase II, Double-Masked, Randomized, Placebo-Controlled Evaluation of Standard Therapy vs. Standard Therapy Combined With Human Monoclonal Anti-Cytomegalovirus Antibody (MSL 109) in the Therapy of AIDS Patients With Cytomegalovirus (CMV) Retinitis[NCT00001061]Phase 2167 participants InterventionalCompleted
Foscarnet-Ganciclovir CMV Retinitis Trial[NCT00000136]Phase 3234 participants (Actual)Interventional1990-03-31Completed
A Phase I Open-Labeled Study of Long Term Combined or Alternating Foscarnet/Ganciclovir Maintenance Therapy for AIDS Patients With CMV Retinitis After Ganciclovir Induction Therapy[NCT00000970]Phase 130 participants InterventionalCompleted
A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure[NCT00000691]Phase 2156 participants InterventionalCompleted
[NCT00005228]0 participants Observational1988-07-31Completed
Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome[NCT00000726]Phase 153 participants InterventionalCompleted
Cytomegalovirus Retinitis Retreatment Trial[NCT00000134]Phase 3279 participants (Actual)Interventional1992-12-31Completed
Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease[NCT00002145]Phase 3145 participants InterventionalCompleted
A Multi-centered, Randomized Study to Evaluate the Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection Compared to Intravenous Acyclovir in Patients With Herpes Zoster From China[NCT02151240]Phase 494 participants (Actual)Interventional2014-05-31Completed
A Randomized, Controlled Study of the Safety and Preventive Efficacy of Oral Ganciclovir When Used in Conjunction With An Intravitreal Ganciclovir Implant in the Treatment of Cytomegalovirus Retinitis[NCT00002134]450 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mortality

(NCT00000136)
Timeframe: All patients enrolled will be followed until a common study closing date, which was chosen to provide a minimum of 1 year of follow-up for all patients enrolled in the trial.

Interventionparticipants (Number)
Foscarnet107
Ganciclovir127

Morbidity

To determine the best therapeutic regimen, using currently approved drugs, for treatment of relapsed cytomegalovirus (CMV) retinitis. (NCT00000134)
Timeframe: Patients will be seen at baseline, monthly for six months, and then every three months until death or termination of the trial

Interventionparticipants (Number)
Intravenous Foscarnet88
Intravenous Ganciclovir93
Combination Therapy93

Reviews

44 reviews available for foscarnet and AIDS-Related Opportunistic Infections

ArticleYear
[Drugs against human cytomegalovirus].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 13, Issue:75

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infec

2002
Progressive outer retinal necrosis presenting with isolated optic neuropathy.
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infection

2004
[Therapy for cytomegalovirus infection].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Ganc

2006
Cytomegalovirus retinitis in patients with AIDS: current status.
    The Medical journal of Australia, 1995, Nov-06, Volume: 163, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Ganci

1995
Foscarnet. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections.
    Drugs, 1994, Volume: 48, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus; Drug Administration Schedule; Drug Interacti

1994
Local therapy for cytomegalovirus retinopathy.
    American journal of ophthalmology, 1995, Volume: 120, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents, Local; Cytomegalovirus Retinitis; Dela

1995
CMV retinitis treatment.
    Optometry and vision science : official publication of the American Academy of Optometry, 1995, Volume: 72, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Humans

1995
Promising new treatments for cytomegalovirus retinitis.
    JAMA, 1995, May-10, Volume: 273, Issue:18

    Topics: AIDS-Related Opportunistic Infections; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants

1995
[Cytomegalovirus infections in AIDS].
    La Revue du praticien, 1995, Mar-15, Volume: 45, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cytomegalovirus Infection

1995
Current management of cytomegalovirus disease in patients with AIDS.
    AIDS research and human retroviruses, 1994, Volume: 10, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Therapy, Combination; Foscarn

1994
Cytomegalovirus retinitis in persons with AIDS. Selecting therapy for a sight-threatening disease.
    Postgraduate medicine, 1995, Volume: 97, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Humans; Mu

1995
Adverse effects and drug interactions of clinical importance with antiviral drugs.
    Drug safety, 1994, Volume: 10, Issue:4

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Amantadine; Antiviral Agents; Didanosine; Drug Int

1994
Retinal disease associated with AIDS.
    Australian and New Zealand journal of ophthalmology, 1993, Volume: 21, Issue:2

    Topics: AIDS-Related Opportunistic Infections; CD4-Positive T-Lymphocytes; Cytomegalovirus Infections; Eye I

1993
Oral CMV lesions and the HIV infected. Early recognition can help prevent morbidity.
    Journal of the American Dental Association (1939), 1993, Volume: 124, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Ganciclovir; HIV Infec

1993
[Resistance of herpes simplex viruses to antiviral drugs].
    Pathologie-biologie, 1993, Volume: 41, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; AIDS-Related Opportunistic Infections; DNA-Directed D

1993
Controversies in the treatment of cytomegalovirus retinitis: foscarnet versus ganciclovir.
    Infectious agents and disease, 1995, Volume: 4, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus R

1995
Nephrogenic diabetes insipidus and renal tubular acidosis secondary to foscarnet therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1996, Volume: 27, Issue:3

    Topics: Acidosis, Renal Tubular; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalov

1996
A foveal-sparing pattern of cytomegalovirus retinitis in the acquired immunodeficiency syndrome.
    Australian and New Zealand journal of ophthalmology, 1996, Volume: 24, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease P

1996
Cytomegalovirus polyradiculopathy treated successfully with foscarnet.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Foscarne

1996
Current management of cytomegalovirus retinitis in AIDS update on ganciclovir and foscarnet for CMV infections.
    Advances in experimental medicine and biology, 1996, Volume: 394

    Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cytomegalovirus Retinitis; Foscarn

1996
Viral lesions of the mouth in HIV-infected patients.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:1

    Topics: 2-Aminopurine; Acyclovir; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cytomegalovirus In

1997
[Treatment of cytomegalovirus infections in HIV infection].
    Presse medicale (Paris, France : 1983), 1996, Dec-14, Volume: 25, Issue:39

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Cytomegalovirus

1996
Pharmacologic management of cytomegalovirus retinitis: review of current and future therapeutic modalities.
    Journal of the American Optometric Association, 1997, Volume: 68, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Ganci

1997
Cytomegalovirus retinitis: diagnosis and status of systemic therapy.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Diagnosis, Diffe

1997
Management strategies for patients with cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalo

1997
Therapeutic options for resistant cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus

1997
Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
    The New England journal of medicine, 1997, Jul-10, Volume: 337, Issue:2

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalo

1997
Combination antiviral therapy for cytomegalovirus disease in patients with AIDS.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, C

1997
Management of CMV retinitis in HIV infected patients.
    Genitourinary medicine, 1997, Volume: 73, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytome

1997
New treatment options for CMV retinitis in AIDS.
    Advance for nurse practitioners, 1997, Volume: 5, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Co

1997
[Cytomegalovirus retinitis].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retin

1998
Local therapy for cytomegalovirus retinitis.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:2

    Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; C

1998
Ganciclovir and foscarnet efficacy in AIDS-related CMV polyradiculopathy.
    The Journal of infection, 1998, Volume: 36, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Inf

1998
Cytomegalovirus infection in patients with HIV infection.
    The Mount Sinai journal of medicine, New York, 1999, Volume: 66, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto

1999
Clinically resistant cytomegalovirus retinitis.
    Seminars in ophthalmology, 1995, Volume: 10, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis;

1995
Cytomegalovirus: disease syndromes and treatment.
    Current clinical topics in infectious diseases, 1999, Volume: 19

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Central Nervous System Diseases; Chorioreti

1999
Management of CMV infections in HIV-infected patients.
    Advances in experimental medicine and biology, 1999, Volume: 458

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytos

1999
Economic evaluation of systemic treatments for cytomegalovirus retinitis in patients with AIDS.
    PharmacoEconomics, 2001, Volume: 19, Issue:5 Pt 2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis

2001
Cytomegalovirus infection: the point in 2001.
    HIV medicine, 2001, Volume: 2, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiv

2001
Management of genital herpes in HIV-infected patients.
    Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:2

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral A

2001
Prevention and treatment of VZV infections in patients with HIV.
    Herpes : the journal of the IHMF, 2001, Volume: 8, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Chickenpox; Chickenpox Va

2001
Aseptic meningitis and optic neuritis preceding varicella-zoster progressive outer retinal necrosis in a patient with AIDS.
    AIDS (London, England), 2002, May-03, Volume: 16, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Ant

2002
Management of CMV disease in HIV infection.
    International journal of STD & AIDS, 1999, Volume: 10, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto

1999
[Clinical aspects and therapy of infection with cytomegalovirus].
    Der Internist, 1992, Volume: 33, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Ganc

1992

Trials

43 trials available for foscarnet and AIDS-Related Opportunistic Infections

ArticleYear
Visual loss in patients with cytomegalovirus retinitis and acquired immunodeficiency syndrome before widespread availability of highly active antiretroviral therapy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Monoclonal; Antiretroviral Therapy, Highly

2003
Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis.
    The Journal of infectious diseases, 2003, Mar-01, Volume: 187, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cohort Studies; Cytomegalovirus; Cyt

2003
A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus re
    Antiviral research, 2004, Volume: 64, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Monoclonal; Antiviral Agents; Cytomegalovi

2004
Foscarnet. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections.
    Drugs, 1994, Volume: 48, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus; Drug Administration Schedule; Drug Interacti

1994
Antiviral effects of foscarnet and ganciclovir therapy on human immunodeficiency virus p24 antigen in patients with AIDS and cytomegalovirus retinitis. Studies of Ocular Complications of AIDS Research Group in collaboration with AIDS Clinical Trials Group
    The Journal of infectious diseases, 1995, Volume: 172, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antigen-Antibody Complex; Cytomegalovirus Retinitis; Female;

1995
Treatment of AIDS-associated gastrointestinal cytomegalovirus infection with foscarnet and ganciclovir: a randomized comparison.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antigens, Viral; Cytomegalovirus; Cytomegalovirus Infe

1995
Foscarnet and ganciclovir pharmacokinetics during concomitant or alternating maintenance therapy for AIDS-related cytomegalovirus retinitis.
    Clinical pharmacology and therapeutics, 1995, Volume: 57, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Administration Schedul

1995
Dose-related difference in progression rates of cytomegalovirus retinopathy during foscarnet maintenance therapy. AIDS Clinical Trials Group Protocol 915 Team.
    American journal of ophthalmology, 1995, Volume: 119, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Re

1995
Foscarnet decreases human immunodeficiency virus RNA.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Cyt

1995
Morbidity and toxic effects associated with ganciclovir or foscarnet therapy in a randomized cytomegalovirus retinitis trial. Studies of ocular complications of AIDS Research Group, in collaboration with the AIDS Clinical Trials Group.
    Archives of internal medicine, 1995, Jan-09, Volume: 155, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retin

1995
Foscarnet or ganciclovir for treatment of AIDS and CMV retinitis.
    The American journal of medicine, 1995, Volume: 98, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Clinical Trials as Topic; Cytomegalovirus Retinitis; Foscarne

1995
Phase II dose-ranging trial of foscarnet salvage therapy for cytomegalovirus retinitis in AIDS patients intolerant of or resistant to ganciclovir (ACTG protocol 093). AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases.
    AIDS (London, England), 1994, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Resi

1994
Randomized phase I trial of two different combination foscarnet and ganciclovir chronic maintenance therapy regimens for AIDS patients with cytomegalovirus retinitis: AIDS clinical Trials Group Protocol 151.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:1

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Cells, Cultured; Clinical Protocols; Cytom

1994
Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. 4. Visual outcomes. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group.
    Ophthalmology, 1994, Volume: 101, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Female; Foscarnet; Fundus O

1994
High dose intravitreal foscarnet in the treatment of cytomegalovirus retinitis in AIDS.
    The British journal of ophthalmology, 1994, Volume: 78, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Female; Foscarnet; Humans;

1994
Effect of foscarnet induction treatment on quantitation of human cytomegalovirus (HCMV) DNA in peripheral blood polymorphonuclear leukocytes and aqueous humor of AIDS patients with HCMV retinitis. The Italian Foscarnet Study Group.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Aqueous Humor; Cytomegalovirus; Cytomegalovirus Retini

1994
Safety of alternating ganciclovir and foscarnet maintenance therapy in human immunodeficiency virus (HIV)-related cytomegalovirus infections. An open-labeled pilot study.
    Scandinavian journal of infectious diseases, 1994, Volume: 26, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Drug Administration Schedu

1994
Foscarnet treatment of cytomegalovirus gastrointestinal infections in acquired immunodeficiency syndrome patients who have failed ganciclovir induction.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Drug Resistance; Foscarnet

1993
A dose-ranging study of daily maintenance intravenous foscarnet therapy for cytomegalovirus retinitis in AIDS.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:2

    Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarne

1993
Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The Cytomegalovirus Retreatment Trial. The Studies of Ocular Complications of AIDS Research Group in Collaboration
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Ther

1996
Controversies in the treatment of cytomegalovirus retinitis: foscarnet versus ganciclovir.
    Infectious agents and disease, 1995, Volume: 4, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus R

1995
Use of antiherpes drugs and the risk of Kaposi's sarcoma: data from the Multicenter AIDS Cohort Study.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:6

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Bisexuality; Case-Control Studie

1996
Assessment of cytomegalovirus retinitis. Clinical evaluation vs centralized grading of fundus photographs. Studies of Ocular Complications of AIDS Research Group, AIDS Clinical Trials Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease P

1996
Measuring visual function and quality of life in patients with cytomegalovirus retinitis. Development of a questionnaire. Studies of Ocular Complication of AIDS Research Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cross-Sectional Studies; Cytomegalov

1996
Clinical vs photographic assessment of treatment of cytomegalovirus retinitis. Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial Report 8. Studies of Ocular Complications of AIDS Research Group, AIDS Clinical Trials Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet

1996
Convenient twice daily foscarnet in induction therapy of AIDS-associated cytomegalovirus retinitis. The Foscarnet Italian Study Group.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Admi

1997
[Prophylaxis secondary to retinitis by CMV in patients with AIDS: the efficacy of an intermittent schedule of 3 days/week].
    Enfermedades infecciosas y microbiologia clinica, 1997, Volume: 15, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Admi

1997
Effect of foscarnet on quantities of cytomegalovirus and human immunodeficiency virus in blood of persons with AIDS.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1996
Treatment of gastrointestinal cytomegalovirus infection with twice-daily foscarnet: a pilot study of safety, efficacy, and pharmacokinetics in patients with AIDS.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Animals; Antiviral

1997
Cytomegalovirus (CMV) culture results, drug resistance, and clinical outcome in patients with AIDS and CMV retinitis treated with foscarnet or ganciclovir. Studies of Ocular Complications of AIDS (SOCA) in collaboration with the AIDS Clinical Trial Group.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections

1997
Rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis: the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS (SOCA) Research Group in Collaboration with the AIDS Clinical Trials Group
    American journal of ophthalmology, 1997, Volume: 124, Issue:1

    Topics: Adolescent; Adult; Age Factors; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphoc

1997
Comparison of pharmacokinetics and dynamics of two dosage regimens of foscarnet in AIDS patients with Cytomegalovirus retinitis.
    European journal of clinical pharmacology, 1997, Volume: 52, Issue:5

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Calcium; Cytomegalovirus

1997
Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Biopsy; Cytomegalovirus Infections; Esophagitis; Foscarnet; G

1998
Renal tolerance of combined treatment with foscarnet and indinavir.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Drug The

1998
[Cytomegalovirus polyradiculomyelopathy in AIDS].
    Medicina, 1998, Volume: 58, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Drug The

1998
Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study.
    Journal of acquired immune deficiency syndromes (1999), 1999, Aug-01, Volume: 21, Issue:4

    Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1999
Cytomegalovirus retinitis in advanced HIV-infected patients treated with protease inhibitors: incidence and outcome over 2 years.
    Journal of acquired immune deficiency syndromes (1999), 1999, Nov-01, Volume: 22, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Drug

1999
Induction and maintenance therapy of cytomegalovirus central nervous system infection in HIV-infected patients.
    AIDS (London, England), 2000, Mar-31, Volume: 14, Issue:5

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovir

2000
Effect of a 14-day course of foscarnet on cytomegalovirus (CMV) blood markers in a randomized study of human immunodeficiency virus-infected patients with persistent CMV viremia. Agence National de Recherche du SIDA 023 Study Group.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 28, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antigens, Viral; Antiviral Agents; Biomarkers; Cytomegaloviru

1999
A double-blind placebo-controlled crossover trial of intravenous magnesium sulfate for foscarnet-induced ionized hypocalcemia and hypomagnesemia in patients with AIDS and cytomegalovirus infection.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Calcium; Cross-Ove

2000
Risk factors for advancement of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. Studies of Ocular Complications of AIDS Research Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2000, Volume: 118, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD8-Positive T-Lymphocytes; Cytomegalovirus

2000
Safety of oral versus intravenous hydration during induction therapy with intravenous foscarnet in AIDS patients with cytomegalovirus infections.
    International journal of STD & AIDS, 2000, Volume: 11, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; AIDS-Related Opportunistic Infectio

2000
Foscarnet administered by portable infusion device in AIDS patients with CMV infection.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Dose-Res

1997

Other Studies

158 other studies available for foscarnet and AIDS-Related Opportunistic Infections

ArticleYear
Management of ganciclovir-resistant cytomegalovirus retinitis in HIV infection in the era of antiretroviral therapy.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:11

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; HIV I

2014
Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:9

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug

2014
Perivascular hypofluorescence in frosted branch angiitis.
    Ophthalmic surgery, lasers & imaging retina, 2015, Volume: 46, Issue:3

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count;

2015
Management of cytomegalovirus retinitis in HIV infection in the era of highly active antiretroviral therapy.
    International journal of STD & AIDS, 2015, Volume: 26, Issue:10

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Human

2015
Progressive hypertrophic genital herpes in an HIV-infected woman despite immune recovery on antiretroviral therapy.
    Infectious diseases in obstetrics and gynecology, 2008, Volume: 2008

    Topics: Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Aminoquinolines; Antineoplast

2008
Successful treatment of cytomegalovirus polyradiculopathy in a 9-year-old child with congenital human immunodeficiency virus infection.
    Journal of child neurology, 2009, Volume: 24, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Brain; Child; Cytomegalovirus Infections; D

2009
Mortality associated with resistant cytomegalovirus among patients with cytomegalovirus retinitis and AIDS.
    Ophthalmology, 2010, Volume: 117, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agent

2010
Anogenital pseudotumoral herpes and HIV infection: a new challenge for diagnosis and treatment.
    AIDS (London, England), 2012, Feb-20, Volume: 26, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Carcinoma, Squamous Cell; Cidofovir;

2012
Antiviral therapy for cytomegalovirus infections in pediatric patients.
    Seminars in pediatric infectious diseases, 2002, Volume: 13, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adolescent; Adult; AIDS-Related Opportunis

2002
Intravitreal antivirals in the management of patients with acquired immunodeficiency syndrome with progressive outer retinal necrosis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2002, Volume: 120, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Drug Therapy, Combination; Female; F

2002
Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2002, Volume: 25, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; DNA-Directed DNA Polymera

2002
[Bilateral uveitis with definitive hypotony caused by systemic cidofovir].
    Journal francais d'ophtalmologie, 2003, Volume: 26, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Cidofovir; Ciliary Body; Cytomegalovirus Retinitis; Cytosine;

2003
Macular CMV retinitis: a case report.
    Bulletin de la Societe belge d'ophtalmologie, 2004, Issue:293

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Fatal Out

2004
Intravitreal foscarnet for cytomegalovirus retinitis in patients with AIDS.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88, Issue:1

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Fem

2005
FDA notifications. FDA approves generic foscarnet sodium injection.
    AIDS alert, 2005, Volume: 20, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Approval; F

2005
Drugs for AIDS and associated infections.
    The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga

1995
Crescentic glomerulonephritis and crystals within glomerular capillaries in an AIDS patient treated with foscarnet.
    American journal of nephrology, 1995, Volume: 15, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Crystallization; Cytomegalovirus Retinitis; Foscarnet;

1995
A sensitive and specific polymerase chain reaction-based assay for the diagnosis of cytomegalovirus retinitis.
    American journal of ophthalmology, 1995, Volume: 120, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Base Sequence; Cytomegalovirus; Cytomegalovirus Retinitis; DN

1995
Can antiviral agents decrease the occurrence of Kaposi's sarcoma? Clinical Epidemiology Group from Centres d'Information et de Soins de l'Immunodéficience Humaine.
    Lancet (London, England), 1995, Aug-26, Volume: 346, Issue:8974

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Bias; Female; Follow-Up Studies;

1995
Cytomegalovirus ventriculoencephalitis in AIDS patients.
    Scandinavian journal of infectious diseases, 1995, Volume: 27, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Autopsy; Brain; Cerebral Ventricles; Cerebrospinal Flu

1995
Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir.
    American journal of ophthalmology, 1995, Volume: 119, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus; Cytomegalovirus Retinitis; Disease Pr

1995
[Lesions of the conus medullaris and the cauda equina caused by cytomegalovirus in HIV infection. 7 cases].
    Presse medicale (Paris, France : 1983), 1995, Mar-18, Volume: 24, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Cauda Equina; Cyto

1995
[Foscarnet related vulvar ulcers. Description of 2 AIDS patients].
    Enfermedades infecciosas y microbiologia clinica, 1995, Volume: 13, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Female; Foscarnet; Humans; Ulcer; Vulvar Diseases

1995
Intraocular sustained drug release devices.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Delayed-Action Preparations; Drug

1995
Cytomegalovirus esophagitis in AIDS: a prospective evaluation of clinical response to ganciclovir therapy, relapse rate, and long-term outcome.
    The American journal of medicine, 1995, Volume: 98, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Drug Administration Schedu

1995
AIDS-associated Kaposi's sarcoma.
    Science (New York, N.Y.), 1995, Feb-24, Volume: 267, Issue:5201

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; AIDS-Related Opportunistic Infections; Female; Foscar

1995
Phosphonoformate for CMV retinitis in AIDS.
    The American journal of medicine, 1995, Volume: 98, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Administration Schedule; Fosc

1995
[Cytomegaloviruses--clinical aspects and therapy].
    Therapeutische Umschau. Revue therapeutique, 1994, Volume: 51, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Humans

1994
Resolution of oral hairy leukoplakia during treatment with foscarnet.
    AIDS (London, England), 1994, Volume: 8, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Herpesviridae In

1994
Two AIDS patients with life-threatening pancreatitis successfully treated, one with ganciclovir the other with foscarnet.
    Acta clinica Belgica, 1994, Volume: 49, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Female; Foscarnet; Gancicl

1994
[Current developments in antiviral chemotherapy. Part 4: Foscarnet, zidovudine, didanosine].
    Fortschritte der Medizin, 1994, May-10, Volume: 112, Issue:13

    Topics: AIDS-Related Opportunistic Infections; Didanosine; Dose-Response Relationship, Drug; Drug Administra

1994
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4

    Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1994
Combined therapy with ganciclovir and foscarnet for cytomegalovirus polyradiculomyelitis in patients with AIDS.
    The American journal of medicine, 1994, Volume: 97, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Drug Therapy, Combination;

1994
[Foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome].
    Nippon Ganka Gakkai zasshi, 1994, Volume: 98, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Re

1994
Actinomyces infection of a cytomegalovirus esophageal ulcer in two patients with acquired immunodeficiency syndrome.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:9

    Topics: Actinomycosis; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Esophageal

1994
Polyradiculopathy due to cytomegalovirus infection: report of a case in which an AIDS patient responded to foscarnet therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus; C

1994
Central venous catheter infections in AIDS patients receiving treatment for cytomegalovirus disease.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Bacterial Infections; Catheterization, Central Venous; Cathet

1994
Efficacy of intravitreal foscarnet in a patient with AIDS.
    The New England journal of medicine, 1994, Mar-24, Volume: 330, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Humans; Injections; Mal

1994
Retinal detachment in patients with acquired immunodeficiency syndrome.
    German journal of ophthalmology, 1994, Volume: 3, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Follow-Up Studie

1994
The development of cytomegalovirus encephalitis in AIDS patients receiving ganciclovir.
    The American journal of medicine, 1994, Volume: 96, Issue:5

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Cerebral Ventricles; Confusion; Cytomegalovirus

1994
Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis.
    American journal of ophthalmology, 1994, Jun-15, Volume: 117, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Administration Schedul

1994
Combination ganciclovir and foscarnet in the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Drug Resistance, Microbial;

1993
[Herpes zoster during foscarnet treatment in an AIDS patient].
    Medicina clinica, 1993, Oct-16, Volume: 101, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis

1993
Long-term visual morbidity of cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
    Ophthalmology, 1993, Volume: 100, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Foscarnet; Ganciclovir; Hum

1993
Risk factors for development of rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis.
    American journal of ophthalmology, 1993, Dec-15, Volume: 116, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis; Follow-Up Studies; Foscarnet; Ganc

1993
Foscarnet-resistant herpes simplex virus infection in patients with AIDS.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Drug Resistance, Microbial; Drug Therapy, C

1994
Ganciclovir intraocular device and patient survival.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1994, Volume: 112, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis

1994
Ganciclovir intraocular device and patient survival.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1994, Volume: 112, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cytomegalovirus Retinitis

1994
[Acyclovir-resistant Herpes simplex viruses in HIV-infected patients].
    Schweizerische medizinische Wochenschrift, 1993, Dec-28, Volume: 123, Issue:51-52

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Drug Resistance, Microbial; Female; Foscarn

1993
Recurrence of presumed varicella-zoster virus retinopathy in patients with acquired immunodeficiency syndrome.
    American journal of ophthalmology, 1993, Jul-15, Volume: 116, Issue:1

    Topics: Acyclovir; Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Foscarnet; Fundus Ocu

1993
Penile ulceration with foscarnet therapy.
    AIDS (London, England), 1993, Volume: 7, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Humans; Male; Penile D

1993
Reversible cardiac dysfunction associated with foscarnet therapy for cytomegalovirus esophagitis in an AIDS patient.
    American heart journal, 1993, Volume: 125, Issue:5 Pt 1

    Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; AIDS-Related Opportunistic Infections; Cyt

1993
Concurrent use of ganciclovir and foscarnet to treat cytomegalovirus infection in AIDS patients.
    The Journal of infectious diseases, 1993, Volume: 167, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Demography; Drug Therapy,

1993
Intravitreal foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome.
    American journal of ophthalmology, 1993, May-15, Volume: 115, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Eye Infections, Viral; Foscarnet;

1993
[Foscarnet and genital lesions].
    Medicina clinica, 1993, May-08, Volume: 100, Issue:18

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Humans; Male; P

1993
Foscarnet penetrates the blood-brain barrier: rationale for therapy of cytomegalovirus encephalitis.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Blood-Brain Barrier; Cytomegalovirus Infections; Encep

1993
Pathophysiology and treatment of clinically resistant cytomegalovirus retinitis.
    Ophthalmology, 1993, Volume: 100, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus; Cytomegalovirus Infections; Drug Resi

1993
Acalculous cholecystitis associated with cytomegalovirus and sclerosing cholangitis in a patient with acquired immunodeficiency syndrome.
    Canadian journal of surgery. Journal canadien de chirurgie, 1993, Volume: 36, Issue:4

    Topics: Abdominal Pain; Acute Disease; Adult; AIDS-Related Opportunistic Infections; Ampulla of Vater; Biops

1993
Therapy for cytomegalovirus retinitis: still no silver lining.
    JAMA, 1996, Jan-10, Volume: 275, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus R

1996
Double resistance to ganciclovir and foscarnet of four human cytomegalovirus strains recovered from AIDS patients.
    Journal of medical virology, 1995, Volume: 47, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cell Line; Cytomegalovirus; Cytomega

1995
[Clinical manifestations and course of cytomegalovirus colitis in AIDS patients].
    Schweizerische medizinische Wochenschrift, 1995, Dec-16, Volume: 125, Issue:50

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cohort Studies; Colitis; Colonoscopy

1995
[Ulcer in the urethral meatus and HIV infection].
    Enfermedades infecciosas y microbiologia clinica, 1995, Volume: 13, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Drug Eru

1995
Foscarnet-resistant multidermatomal zoster in a patient with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:5

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Drug Resistance, Microbia

1995
Prognosis and response to therapy of cytomegalovirus encephalitis and meningomyelitis in AIDS.
    Neurology, 1996, Volume: 46, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Base Sequence; Cerebrospi

1996
Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered f
    Journal of virology, 1996, Volume: 70, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Amino Acid Sequence; Base Sequence; Cytomegalovirus; Cytomega

1996
Treatment of clinically resistant cytomegalovirus retinitis with combined intravitreal injections of ganciclovir and foscarnet.
    American journal of ophthalmology, 1996, Volume: 122, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Ret

1996
Cytomegalovirus retinitis and viral resistance. Prevalence of resistance at diagnosis, 1994. Cytomegalovirus Retinitis and Viral Resistance Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Cytomegalovirus; Cytomega

1996
Occurrence of cytomegalovirus retinitis after human immunodeficiency virus immunosuppression.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lympho

1996
Serous retinal detachments in a patient with clinically resistant cytomegalovirus retinitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:7

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomega

1996
Four dually resistant human cytomegalovirus strains from AIDS patients: single mutations in UL97 and UL54 open reading frames are responsible for ganciclovir- and foscarnet-specific resistance, respectively.
    Scandinavian journal of infectious diseases. Supplementum, 1995, Volume: 99

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections

1995
Treatment of cytomegalovirus retinitis in patients with AIDS.
    Annals of internal medicine, 1996, Jul-15, Volume: 125, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto

1996
New developments in the treatment of CMV retinitis.
    Ophthalmology, 1996, Volume: 103, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytos

1996
Chronic ulcerating acyclovir-resistant varicella zoster lesions in an AIDS patient.
    Scandinavian journal of infectious diseases, 1995, Volume: 27, Issue:6

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Chronic Disease; Drug Res

1995
Chronic varicella presenting as disseminated pinpoint-sized papules in a man infected with the human immunodeficiency virus.
    Dermatology (Basel, Switzerland), 1996, Volume: 192, Issue:1

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Chickenpox; Chronic Disea

1996
Nephrogenic diabetes insipidus associated with foscarnet--a case report.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1996
Rapid development of renal insufficiency with the simultaneous administration of amphotericin B and foscarnet.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiviral Agents; C

1996
Cytomegalovirus papillitis in patients with acquired immune deficiency syndrome. Visual prognosis of patients treated with ganciclovir and/or foscarnet.
    Ophthalmology, 1996, Volume: 103, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Cytomega

1996
Cytomegalovirus pneumonia manifesting as a focal mass in acquired immunodeficiency syndrome.
    Southern medical journal, 1996, Volume: 89, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Biopsy, Needle; Cytomegalovirus Infe

1996
[Long term survival in an HIV-immunosuppressed patient treated with foscarnet].
    Anales de medicina interna (Madrid, Spain : 1984), 1996, Volume: 13, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cytomegaloviru

1996
[Early diagnosis and treatment of cytomegalovirus polyradiculoneuritis in a child infected by HIV].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1996, Volume: 3, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Child; Cytomegalovirus Infections; Drug Therapy, Combination;

1996
Repair of retinal detachments due to herpes varicella-zoster virus retinitis in patients with acquired immune deficiency syndrome.
    Ophthalmology, 1997, Volume: 104, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Foscarnet; Ganciclovir; Herpes Zoste

1997
Early foscarnet failure in herpes simplex virus infection in a patient with AIDS.
    AIDS (London, England), 1997, Mar-15, Volume: 11, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Foscarnet; Herpes Simplex; Humans; M

1997
Combined intravenous ganciclovir and foscarnet for children with recurrent cytomegalovirus retinitis.
    Ophthalmology, 1995, Volume: 102, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Cytomegalovirus Re

1995
Quantitative systemic and local evaluation of the antiviral effect of ganciclovir and foscarnet induction treatment on human cytomegalovirus gastrointestinal disease of patients with AIDS. Italian Foscarnet GID Study Group.
    Antiviral research, 1997, Volume: 34, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections

1997
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
    The Western journal of medicine, 1997, Volume: 166, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cyto

1997
Central venous line infections in AIDS.
    The Journal of infection, 1997, Volume: 34, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1997
Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients.
    The Journal of infectious diseases, 1997, Volume: 175, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Base Sequence; Cytomegalovirus; Cytomegalov

1997
Management of varicella zoster virus retinitis in AIDS.
    The British journal of ophthalmology, 1997, Volume: 81, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; AIDS-Related Opportunistic Infections; Analysi

1997
Re-evaluation of time to progression of foscarnet salvage therapy for cytomegalovirus retinitis in AIDS patients clinically resistant to ganciclovir.
    AIDS (London, England), 1997, Volume: 11, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease Progress

1997
Concurrent ganciclovir and foscarnet treatment for cytomegalovirus encephalitis and retinitis in an infant with acquired immunodeficiency syndrome: case report and review.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, C

1997
Identification and treatment of cytomegalovirus retinitis in patients with AIDS.
    Journal of the American Academy of Nurse Practitioners, 1997, Volume: 9, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retin

1997
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomega

1997
Quantitative cytomegalovirus (CMV) antigenaemia during antiviral treatment of AIDS-related CMV disease.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antigens, Viral; Antiviral Agents; Biomarkers; Cytomeg

1997
Intravitreal ganciclovir treatment in progressive outer retinal necrosis.
    American journal of ophthalmology, 1997, Volume: 124, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease P

1997
Therapy with a combination of intravitreal foscarnet and intravenous ganciclovir in clinically resistant cytomegalovirus retinitis and patients with acquired immunodeficiency syndrome.
    German journal of ophthalmology, 1996, Volume: 5, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus R

1996
Varicella zoster virus retrobulbar optic neuritis preceding retinitis in patients with acquired immune deficiency syndrome.
    Ophthalmology, 1998, Volume: 105, Issue:3

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cerebrospinal Fluid; Fema

1998
AIDS-related herpes simplex virus encephalitis during maintenance foscarnet therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cell Line; Chlorocebus aeth

1998
New issues in the management of cytomegalovirus retinitis in AIDS patients.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Feb-15, Volume: 55, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytos

1998
Cystoid macular edema associated with cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
    American journal of ophthalmology, 1998, Volume: 125, Issue:3

    Topics: Acetazolamide; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents, Non-Steroidal

1998
How to treat the cytomegalovirus troll.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; DNA, Viral; Fos

1998
Therapy for genital herpes in immunocompromised patients: a national survey. The Herpes Simplex Advisory Panel.
    Genitourinary medicine, 1997, Volume: 73, Issue:5

    Topics: 2-Aminopurine; Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Drug Resistance,

1997
Long-lasting remission of cytomegalovirus retinitis without maintenance therapy in human immunodeficiency virus-infected patients.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cytomegalovirus

1998
Optic neuritis heralding varicella zoster virus retinitis in a patient with acquired immunodeficiency syndrome.
    Annals of neurology, 1998, Volume: 43, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antivir

1998
The progressive outer retinal necrosis syndrome: successful treatment with combination antiviral therapy.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:3

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis

1998
Measurement of viral sequences in cerebrospinal fluid of AIDS patients with cerebral white-matter lesions using polymerase chain reaction.
    AIDS (London, England), 1998, Apr-16, Volume: 12, Issue:6

    Topics: Adolescent; Adult; AIDS Dementia Complex; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Br

1998
Lack of efficacy of cidofovir in treating AIDS-related cytomegalovirus retinitis after long-term treatment with ganciclovir.
    AIDS (London, England), 1998, Apr-16, Volume: 12, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytomegalovirus Retinitis;

1998
Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA.
    Archives of internal medicine, 1998, May-11, Volume: 158, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus

1998
Prophylactic argon laser coagulation for rhegmatogenous retinal detachment in AIDS patients with cytomegalovirus retinitis.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1998, Volume: 236, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Foscarnet; Fundu

1998
Immunohistochemical localization of ganciclovir in the human retina.
    Current eye research, 1998, Volume: 17, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Delayed-A

1998
Evaluation of cytomegalovirus retinitis management. Outcome of four years of cytomegalovirus therapy.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1998, Volume: 212, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Body Fluids; CD4 Lymphocyte Count; Cytomega

1998
Mutation in region III of the DNA polymerase gene conferring foscarnet resistance in cytomegalovirus isolates from 3 subjects receiving prolonged antiviral therapy.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Alanine; Antiviral Agents; Cytomegalovirus; Cytomegalo

1998
Diagnostic significance and clinical impact of quantitative assays for diagnosis of human cytomegalovirus infection/disease in immunocompromised patients.
    The new microbiologica, 1998, Volume: 21, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antibodies, Monoclonal; Antigens, Viral; Antiviral Agents; Ce

1998
Identification of crystals in kidneys of AIDS patients treated with foscarnet.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 32, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents;

1998
Foscarnet crystal deposition and renal failure.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 32, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Crystallization; Cytomegalovirus Retinitis;

1998
Suppression of HHV-8 viremia by foscarnet in an HIV-infected patient with Kaposi's sarcoma and HHV-8 associated hemophagocytic syndrome.
    European journal of medical research, 1998, Oct-14, Volume: 3, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; DNA, Viral; Foscarnet; Herpesvirus 8

1998
Cytomegalovirus retinitis and viral resistance: 3. Culture results. CMV Retinitis and Viral Resistance Study Group.
    American journal of ophthalmology, 1998, Volume: 126, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Blood; Cidofovir; Cytomeg

1998
Transient foscarnet-induced hypercalcaemia.
    AIDS (London, England), 1998, Oct-01, Volume: 12, Issue:14

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Female; F

1998
Single amino acid change in DNA polymerase is associated with foscarnet resistance in a varicella-zoster virus strain recovered from a patient with AIDS.
    The Journal of infectious diseases, 1998, Volume: 178 Suppl 1

    Topics: Adult; AIDS-Related Opportunistic Infections; Amino Acid Sequence; Amino Acid Substitution; Antivira

1998
Acyclovir-resistant herpes zoster in human immunodeficiency virus-infected patients: results of foscarnet therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:6

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Drug Res

1998
Risk of developing CMV retinitis following non-ocular CMV end organ disease in AIDS patients.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Biopsy; Cytomegalovirus Infections;

1998
Human herpesvirus 8 DNA load in leukocytes of human immunodeficiency virus-infected subjects: correlation with the presence of Kaposi's sarcoma and response to anticytomegalovirus therapy.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Ganc

1999
[Treatment of CMV retinitis with intravitreal foscarnet].
    Journal francais d'ophtalmologie, 1998, Volume: 21, Issue:10

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Disease Progress

1998
[Cytomegalovirus (CMV) retinitis in AIDS. Gancilovir implantation in comparison with systemic therapy].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1999, Volume: 96, Issue:1

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cyto

1999
Dosing guidelines for foscarnet and trimetrexate.
    Formulary (Cleveland, Ohio), 1995, Volume: 30, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Clinical Protocols; Dose-Response Relationship, Drug; Foscarn

1995
Expression of the late cytomegalovirus (CMV) pp150 transcript in leukocytes of AIDS patients is associated with a high viral DNA load in leukocytes and presence of CMV DNA in plasma.
    The Journal of infectious diseases, 1999, Volume: 179, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections

1999
Images in clinical medicine. Severe herpes simplex infection.
    The New England journal of medicine, 1999, Apr-22, Volume: 340, Issue:16

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Face; Foscarnet; Herpes Simplex; Hum

1999
Impact of cerebrospinal fluid PCR on the management of HIV-infected patients with varicella-zoster virus infection of the central nervous system.
    Journal of neurovirology, 1999, Volume: 5, Issue:2

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Central Nervous System In

1999
Characterization of the DNA polymerase and thymidine kinase genesof herpes simplex virus isolates from AIDS patients in whom acyclovirand foscarnet therapy sequentially failed.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:2

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; DNA-Directed DNA Polymerase; Dru

1999
Kaposi's sarcoma and non-Hodgkin's lymphoma incidence trends in AIDS Clinical Trial Group study participants.
    Journal of acquired immune deficiency syndromes (1999), 1999, Aug-01, Volume: 21 Suppl 1

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Clinical Trials as Topic;

1999
[Lumbosacral polyradiculomyelitis caused by herpes simplex virus (HSV) in a patient with AIDS].
    Anales de medicina interna (Madrid, Spain : 1984), 1999, Volume: 16, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; DNA, Viral; Foscarnet; Herpes Simple

1999
[Lumbosacral and meningeal polyradicular disease in a patient with HIV infection].
    Anales de medicina interna (Madrid, Spain : 1984), 1999, Volume: 16, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Antiviral Agents; Brain; Cytome

1999
Survival differences associated with treatment of cytomegalovirus retinitis in Maryland patients with AIDS, 1987-1994.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Jul-01, Volume: 56, Issue:13

    Topics: Adult; Age Factors; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cytome

1999
[Severe cytomegalovirus enteritis in AIDS. Favorable outcome of medical treatment].
    Presse medicale (Paris, France : 1983), 2000, Mar-25, Volume: 29, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Celiac Disease; Cytomegalovirus Infec

2000
Outcome of AIDS-associated cytomegalovirus colitis in the era of potent antiretroviral therapy.
    Journal of clinical gastroenterology, 2000, Volume: 30, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cohort Studies; Colitis; Cytomegalov

2000
Incidence and trends in Kaposi's sarcoma in the era of effective antiretroviral therapy.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jul-01, Volume: 24, Issue:3

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Therapy, Combination;

2000
[Stopping secondary prevention in AIDS patients with inactive CMV retinitis treated with HAART (highly active antiretroviral therapy)].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2000, Volume: 97, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cido

2000
Acyclovir-resistant bilateral keratitis associated with mutations in the HSV-1 thymidine kinase gene.
    Experimental eye research, 2000, Volume: 71, Issue:4

    Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Amino Acid Sequence; Antiviral Agents; Base

2000
High-dose intravitreal ganciclovir and foscarnet for cytomegalovirus retinitis.
    American journal of ophthalmology, 2001, Volume: 131, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Ther

2001
CMV retinitis: a clinical management update.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Algorithms; Antiviral Agents; Cidofovir; Clinical Protocols;

1996
Support for new foscarnet indication for AIDS-related CMV retinitis is mixed.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Combination

1997
Advances in the treatment of CMV.
    PI perspective, 1995, Issue:no 16

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topi

1995
New drug applications sought.
    AIDS alert, 1995, Volume: 10, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Clarithromycin; Cytomegalovirus Retinitis; Drug Approval; Dru

1995
International Congress on Chemotherapy.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:9

    Topics: Adjuvants, Immunologic; AIDS-Related Opportunistic Infections; Aminoquinolines; Anti-Bacterial Agent

1995
CMV: the other virus.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:3

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retin

1996
Guide to CMV management.
    PI perspective, 1996, Issue:no 18

    Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infec

1996
Two-drug treatment effective against recurrent CMV retinitis.
    NIAID AIDS agenda, 1996

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Co

1996
Foscavir receives new indication.
    AIDS alert, 1997, Volume: 12, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; Drug Therapy, Co

1997
Fomivirsen.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytome

1998
[Cytomegalovirus sensitivity to anti-retroviral agents in patients infected with the human immunodeficiency virus with chorioretinitis in Spain].
    Enfermedades infecciosas y microbiologia clinica, 2001, Volume: 19, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Chorioretinitis; Cytomegalovirus; Cy

2001
Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy.
    Journal of medical virology, 2002, Volume: 67, Issue:1

    Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Foscarnet; Herpes Genitalis; Herpes

2002
Atypical healing of cytomegalovirus retinitis. Significance of persistent border opacification.
    Ophthalmology, 1992, Volume: 99, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections

1992
Visual field testing in the management of cytomegalovirus retinitis.
    Ophthalmology, 1992, Volume: 99, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Infections; Eye Infe

1992
When you give foscarnet to patients at home.
    RN, 1992, Volume: 55, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Community Health Nursing; Cytomegalovirus Infections; Foscarn

1992
2.5 years survival with sequential ganciclovir/foscarnet treatment in a patient with acquired immune deficiency syndrome and cytomegalovirus retinitis.
    German journal of ophthalmology, 1992, Volume: 1, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Cataract Extraction; Cytomegalovirus Infections; Drug Adminis

1992
Opportunistic intraocular infections in AIDS.
    Transactions of the American Ophthalmological Society, 1992, Volume: 90

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Choroiditis; Cyto

1992
[Cytomegalovirus retinitis in AIDS. Effectiveness and complications of long-term therapy].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1992, Volume: 89, Issue:5

    Topics: AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Humans; L

1992
Uvula and oesophageal ulcerations with foscarnet.
    Lancet (London, England), 1992, Oct-17, Volume: 340, Issue:8825

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Esophagus; Foscarnet; Huma

1992
Combined and alternating ganciclovir/foscarnet in HIV-related cytomegalovirus encephalitis.
    Lancet (London, England), 1992, Oct-17, Volume: 340, Issue:8825

    Topics: Adult; AIDS-Related Opportunistic Infections; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Ho

1992