formycin and Cell-Transformation--Viral

formycin has been researched along with Cell-Transformation--Viral* in 1 studies

Other Studies

1 other study(ies) available for formycin and Cell-Transformation--Viral

Article	Year
Inhibition of Rous sarcoma virus production by formycin. Virology, 1985, Volume: 145, Issue:1 The effect of formycin, an adenosine analog, on the growth of chick embryo fibroblasts and on Rous sarcoma virus (RSV) production was studied. An adverse effect on cell proliferation was observed in the presence of 10 microM formycin. Treatment with 5 microM formycin for 24 hr reduced by a factor of about 1000 the yield of infections progeny whereas the cell growth remained unaltered. Moreover the few particles released in the presence of formycin showed a markedly decreased ability to synthesize viral cDNA. This impairment was shown to be related to a nonfunctional primer tRNA. Topics: Animals; Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; DNA; DNA, Viral; Formycins; RNA; RNA, Transfer; RNA, Viral	1985

Article

Year

Inhibition of Rous sarcoma virus production by formycin.

Virology, 1985, Volume: 145, Issue:1

The effect of formycin, an adenosine analog, on the growth of chick embryo fibroblasts and on Rous sarcoma virus (RSV) production was studied. An adverse effect on cell proliferation was observed in the presence of 10 microM formycin. Treatment with 5 microM formycin for 24 hr reduced by a factor of about 1000 the yield of infections progeny whereas the cell growth remained unaltered. Moreover the few particles released in the presence of formycin showed a markedly decreased ability to synthesize viral cDNA. This impairment was shown to be related to a nonfunctional primer tRNA.

Topics: Animals; Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Division; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; DNA; DNA, Viral; Formycins; RNA; RNA, Transfer; RNA, Viral

1985