formononetin has been researched along with Weight-Loss* in 1 studies
1 other study(ies) available for formononetin and Weight-Loss
| Article | Year |
|---|---|
Synthesis and biological evaluation of isoflavone fatty acid esters with potential weight loss and hypolipidemic activities.
A series of isoflavone fatty acid esters were designed on the basis of endogenous oleoyl-estrone using estrogen moiety modification strategy. Ten new compounds were synthesized, and their body weight loss and hypolipidemic bioactivities were assayed. Some of these novel compounds could effectively inhibit the differentiation of 3T3-L1 preadipocytes in vitro. The most potent compound 1a significantly decreased the body weight and white adipose tissue weight in a high-fat diet-induced rat model. Also, compound 1a showed good hypolipidemic activity and low toxicity. Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Cell Differentiation; Cell Line; Esters; Fatty Acids; Flavones; Hypolipidemic Agents; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Rats; Weight Loss | 2010 |