formocresol and Osteonecrosis

Accidental injection or leakages of various chemical disinfectants used during root canal preparation into adjacent tissues have been shown to have deleterious effects on surrounding tissue. Formocresol (FC) is an effective intracanal disinfectant used in endodontic procedures. However, it is known to have harmful effects into adjacent tissues. The aim of this article is to present an unusual case in which a 28-year-old male patient developed gingival and bone necrosis after the accidental injection of FC instead of local anesthetic solution for tooth extraction and to review cases in the literature where complications have occurred due to the use of FC.

Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics; Formocresols; Gingiva; Humans; Injections; Male; Maxilla; Medication Errors; Necrosis; Osteonecrosis; Reoperation; Root Canal Preparation; Tooth Extraction; Turkey

A 68-year-old woman received a formocresol pulpectomy of the right lower lateral incisor. The temporary restoration was lost within hours. The next day, the patient suffered continuous pain, the gingiva sloughed, and the alveolar bone was exposed. Four days after treatment, the patient complained of moderate pain. Six days after the pulpectomy, the tooth spontaneously exfoliated. At this time she was referred to our hospital. The clinical diagnosis was chronic alveolitis. Treatment consisted of irrigation of the area. Three weeks after the pulpectomy, the dull pain had subsided, but the alveolar bone of the area showed increased mobility. Five weeks after the pulpectomy, the mobility of the alveolar bone was more significant and a sequestrectomy was performed with the patient under local anesthesia. The sequestrum of necrotic bone was approximately 10 x 5 x 5 mm in size. The patient has been symptom-free for 2 years since the sequestrectomy.

Topics: Aged; Alveolar Process; Dry Socket; Female; Follow-Up Studies; Formocresols; Gingival Diseases; Humans; Osteonecrosis; Pulpectomy; Root Canal Irrigants; Tooth Exfoliation

Topics: Female; Formocresols; Humans; Mandibular Diseases; Middle Aged; Osteomyelitis; Osteonecrosis; Root Canal Irrigants