formic acid has been researched along with Vitamin B 12 Deficiency in 7 studies
formic acid: RN given refers to parent cpd
formic acid : The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.
Vitamin B 12 Deficiency: A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration." | 7.78 | Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration. ( Brosnan, JT; Brosnan, ME; Lamarre, SG; Molloy, AM; Reinke, SN; Sykes, BD, 2012) |
| "Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration." | 3.78 | Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration. ( Brosnan, JT; Brosnan, ME; Lamarre, SG; Molloy, AM; Reinke, SN; Sykes, BD, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MacMillan, L | 1 |
| Tingley, G | 1 |
| Young, SK | 1 |
| Clow, KA | 1 |
| Randell, EW | 1 |
| Brosnan, ME | 2 |
| Brosnan, JT | 2 |
| Lamarre, SG | 1 |
| Molloy, AM | 1 |
| Reinke, SN | 1 |
| Sykes, BD | 1 |
| NORONHA, JM | 1 |
| SREENIVASAN, A | 1 |
| Chanarin, I | 2 |
| Dow, JL | 1 |
| Green, T | 1 |
| Deacon, R | 1 |
| Lumb, M | 1 |
| Perry, J | 1 |
| Shane, B | 1 |
| Stokstad, EL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Folic Acid Clinical Trial (FACT): Biomarker Subgroup Analysis[NCT03981029] | 51 participants (Actual) | Observational | 2011-12-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for formic acid and Vitamin B 12 Deficiency
| Article | Year |
|---|---|
Cobalamin-folate interrelations.
Topics: Anemia, Megaloblastic; Animals; Central Nervous System Diseases; Coenzymes; Folic Acid; Folic Acid D | 1989 |
Vitamin B12-folate interrelationships.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bone Marrow; Folic | 1985 |
5 other studies available for formic acid and Vitamin B 12 Deficiency
| Article | Year |
|---|---|
Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.
Topics: Animals; Carbon; Carbon Dioxide; Cytosol; Folic Acid; Formates; Glycine; Liver; Male; Mitochondria, | 2018 |
Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration.
Topics: Animals; Biomarkers; Brain; Folic Acid Deficiency; Formates; Homocysteine; Hyperhomocysteinemia; Liv | 2012 |
Formate metabolism in the vitamin B12-deficient rat.
Topics: Animals; Formates; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1959 |
The deoxyuridine suppression test and cobalamin-folate interrelations.
Topics: Deoxyuridine; Formates; Formyltetrahydrofolates; Humans; Vitamin B 12 Deficiency | 1993 |
Trichloroethylene induced vitamin B(12) and folate deficiency leads to increased formic acid excretion in the rat.
Topics: Anesthetics, Inhalation; Animals; Bacteria; Biotransformation; Catalase; Folic Acid Deficiency; Form | 2000 |