formic acid has been researched along with Pregnancy in 23 studies
formic acid: RN given refers to parent cpd
formic acid : The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfasalazine has been identified as a candidate molecule to be investigated as an intervention to treat preterm pre-eclampsia during pregnancy." | 4.31 | An LC-MS/MS method for the simultaneous quantitation of sulfasalazine and sulfapyridine in human placenta. ( Brownfoot, F; Cluver, C; Decloedt, E; Kellermann, T; Louw, V, 2023) |
| " Methanol is teratogenic in rodents and, although the exact toxic species is not known, teratogenesis may result from the enzymatic biotransformation of H3COH to formaldehyde (CH2O) and formic acid causing increased biological reactivity and toxicity." | 1.32 | Glutathione depletion modulates methanol, formaldehyde and formate toxicity in cultured rat conceptuses. ( Dixon, M; Hansen, JM; Harris, C, 2004) |
| " MeOH has been shown to be developmentally toxic in mice and rats both in vivo and in vitro, but rodents neither accumulate formate nor develop acidosis after MeOH exposure." | 1.29 | Developmental toxicity of formate and formic acid in whole embryo culture: a comparative study with mouse and rat embryos. ( Andrews, JE; Ebron-McCoy, M; Kavlock, RJ; Rogers, JM, 1995) |
| "Mouse embryos develop exencephaly when dams are exposed by inhalation to high concentrations (> or = 10,000 ppm) of methanol on gestational day 8 (GD8; copulation plug = GD0)." | 1.29 | Role of formate in methanol-induced exencephaly in CD-1 mice. ( Bolon, B; Dorman, DC; Elswick, B; LaPerle, KM; Struve, MF; Welsch, F; Wong, BA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 5 (21.74) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, BI | 1 |
| Cady, SV | 1 |
| Aceto, HW | 1 |
| Louw, V | 1 |
| Brownfoot, F | 1 |
| Cluver, C | 1 |
| Decloedt, E | 1 |
| Kellermann, T | 1 |
| Strickland, AL | 1 |
| Blacketer, S | 1 |
| Molberg, K | 1 |
| Markantonis, J | 1 |
| Lucas, E | 1 |
| Brosnan, JT | 5 |
| Brosnan, ME | 5 |
| Tingley, G | 1 |
| MacMillan, L | 2 |
| Harnett, B | 2 |
| Pongnopparat, T | 3 |
| Marshall, JD | 1 |
| Luthra, G | 1 |
| Vuckovic, I | 1 |
| Bangdiwala, A | 1 |
| Gray, H | 1 |
| Redmon, JB | 1 |
| Barrett, ES | 1 |
| Sathyanarayana, S | 1 |
| Nguyen, RHN | 1 |
| Swan, SH | 1 |
| Zhang, S | 1 |
| Dzeja, P | 1 |
| Macura, SI | 1 |
| Nair, KS | 1 |
| Camperi, J | 1 |
| Pichon, V | 1 |
| Fournier, T | 1 |
| Delaunay, N | 1 |
| Plumptre, L | 1 |
| Masih, SP | 1 |
| Visentin, CE | 1 |
| Berger, H | 1 |
| Lamers, Y | 1 |
| Caudill, MA | 2 |
| Malysheva, OV | 1 |
| O'Connor, DL | 1 |
| Kim, YI | 1 |
| Washburn, SE | 1 |
| Malysheva, O | 1 |
| MacFarlane, AJ | 1 |
| Behan, NA | 1 |
| Vanderhaeghen, S | 1 |
| Lacroix, C | 1 |
| Schwab, C | 1 |
| Ema, M | 1 |
| Naya, M | 1 |
| Yoshida, K | 1 |
| Nagaosa, R | 1 |
| Wang, X | 1 |
| Vernikovskaya, DI | 1 |
| Abdelrahman, DR | 1 |
| Hankins, GD | 1 |
| Ahmed, MS | 1 |
| Nanovskaya, TN | 1 |
| Patel, H | 1 |
| Pietro, ED | 1 |
| MacKenzie, RE | 1 |
| Harris, C | 2 |
| Dixon, M | 1 |
| Hansen, JM | 2 |
| Contreras, KM | 1 |
| Shambaugh, GE | 1 |
| Angulo, MC | 1 |
| Koehler, RR | 1 |
| Andrews, JE | 2 |
| Ebron-McCoy, M | 2 |
| Kavlock, RJ | 1 |
| Rogers, JM | 1 |
| Schmid, K | 1 |
| Schaller, KH | 1 |
| Angerer, J | 1 |
| Lehnert, G | 1 |
| Dorman, DC | 1 |
| Bolon, B | 1 |
| Struve, MF | 1 |
| LaPerle, KM | 1 |
| Wong, BA | 1 |
| Elswick, B | 1 |
| Welsch, F | 1 |
| Brown-Woodman, PD | 1 |
| Huq, F | 1 |
| Hayes, L | 1 |
| Herlihy, C | 1 |
| Picker, K | 1 |
| Webster, WS | 1 |
| Schmid, JE | 1 |
| Svendsgaard, D | 1 |
| Brennecke, SP | 1 |
| Chen, S | 1 |
| King, RG | 1 |
| Boura, AL | 1 |
3 reviews available for formic acid and Pregnancy
| Article | Year |
|---|---|
Formate and its role in amino acid metabolism.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Female; Formates; Humans; Mice; Multienzyme Comple | 2020 |
Formate: The Neglected Member of One-Carbon Metabolism.
Topics: Animals; Dietary Supplements; DNA Methylation; Epigenesis, Genetic; Female; Fetal Development; Forma | 2016 |
Reproductive and developmental toxicity of degradation products of refrigerants in experimental animals.
Topics: Abnormalities, Drug-Induced; Aldehydes; Animals; Carbon Compounds, Inorganic; Carbon Dioxide; Carbon | 2010 |
1 trial available for formic acid and Pregnancy
| Article | Year |
|---|---|
Effect of formic acid treatment on colostrum quality, and on absorption and function of immunoglobulins: a randomized controlled trial in Holstein dairy calves.
Topics: Animals; Animals, Newborn; Cattle; Colostrum; Female; Formates; Immunoglobulin G; Pregnancy | 2022 |
19 other studies available for formic acid and Pregnancy
| Article | Year |
|---|---|
An LC-MS/MS method for the simultaneous quantitation of sulfasalazine and sulfapyridine in human placenta.
Topics: Chromatography, Liquid; Female; Humans; Infant, Newborn; Methanol; Placenta; Pre-Eclampsia; Pregnanc | 2023 |
Effects of Decalcifying Agents of Variable Duration on PD-L1 Immunohistochemistry.
Topics: B7-H1 Antigen; Calcium Chelating Agents; Edetic Acid; Female; Formates; Humans; Hydrochloric Acid; I | 2020 |
Plasma Formate Is Greater in Fetal and Neonatal Rats Compared with Their Mothers.
Topics: Aging; Animals; Animals, Newborn; Female; Fetus; Formates; Liver; Maternal-Fetal Exchange; Mothers; | 2020 |
First and second trimester urinary metabolic profiles and fetal growth restriction: an exploratory nested case-control study within the infant development and environment study.
Topics: Acetates; Adult; Case-Control Studies; Female; Fetal Growth Retardation; Formates; Gestational Age; | 2018 |
First profiling in hydrophilic interaction liquid chromatography of intact human chorionic gonadotropin isoforms.
Topics: Chorionic Gonadotropin; Chromatography, Liquid; Female; Formates; Glycoproteins; Glycosylation; Huma | 2019 |
Formate concentrations in maternal plasma during pregnancy and in cord blood in a cohort of pregnant Canadian women: relations to genetic polymorphisms and plasma metabolites.
Topics: Adult; Amino Acids; Cohort Studies; Female; Fetal Blood; Formates; Genotype; Humans; Methylenetetrah | 2019 |
Formate metabolism in fetal and neonatal sheep.
Topics: Amniotic Fluid; Animals; Animals, Newborn; Female; Fetus; Folic Acid; Formates; Homocysteine; Postpa | 2015 |
Methanogen communities in stools of humans of different age and health status and co-occurrence with bacteria.
Topics: Adolescent; Adult; Age Factors; Aged; Bacteria; Carbohydrate Metabolism; Child; Euryarchaeota; Feces | 2015 |
Simultaneous quantitative determination of bupropion and its three major metabolites in human umbilical cord plasma and placental tissue using high-performance liquid chromatography-tandem mass spectrometry.
Topics: Acetonitriles; Biotransformation; Buffers; Bupropion; Calibration; Chemical Precipitation; Chromatog | 2012 |
Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs.
Topics: Aminohydrolases; Animals; Blotting, Northern; Blotting, Southern; Carbon Radioisotopes; Cell Divisio | 2003 |
Glutathione depletion modulates methanol, formaldehyde and formate toxicity in cultured rat conceptuses.
Topics: Animals; Buthionine Sulfoximine; Cysteine; Embryo, Mammalian; Female; Formaldehyde; Formates; Glutat | 2004 |
Methanol, formaldehyde, and sodium formate exposure in rat and mouse conceptuses: a potential role of the visceral yolk sac in embryotoxicity.
Topics: Animals; Dose-Response Relationship, Drug; Embryo Loss; Female; Formaldehyde; Formates; Maternal Exp | 2005 |
Fetal fuels. VII. Ketone bodies inhibit synthesis of purines in fetal rat brain.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenine; Animals; Brain; Carbon Radioisotopes; Cycloheximide; | 1984 |
Developmental toxicity of formate and formic acid in whole embryo culture: a comparative study with mouse and rat embryos.
Topics: Abnormalities, Drug-Induced; Animals; Culture Techniques; DNA; Dose-Response Relationship, Drug; Emb | 1995 |
[The importance of formic acid excretion in the urine for environmental and occupational medicine questions].
Topics: Administration, Inhalation; Adult; Air Pollution; Child; Circadian Rhythm; Creatinine; Environmental | 1994 |
Role of formate in methanol-induced exencephaly in CD-1 mice.
Topics: Animals; Decidua; Embryonic and Fetal Development; Erythrocyte Count; Female; Fomepizole; Formates; | 1995 |
In vitro assessment of the effect of methanol and the metabolite, formic acid, on embryonic development of the rat.
Topics: Animals; Drug Combinations; Embryonic and Fetal Development; Female; Formates; Humans; Hydrogen-Ion | 1995 |
Effects of combinations of methanol and formic acid on rat embryos in culture.
Topics: Abnormalities, Drug-Induced; Animals; Culture Techniques; Dose-Response Relationship, Drug; Drug Int | 1998 |
Human placental acetylcholine content and release at parturition.
Topics: Acetone; Acetylcholine; Female; Formates; Humans; Labor, Induced; Labor, Obstetric; Placenta; Pregna | 1988 |