formic acid has been researched along with Parkinson Disease in 4 studies
formic acid: RN given refers to parent cpd
formic acid : The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rotenone treatment caused an acute reduction in alpha-synuclein-immunoreactivity, but this was followed 6 months later by a robust increase in aggregate pathology and cytoplasmic inclusions that were similar in appearance to enteric Lewy-bodies in idiopathic PD." | 1.35 | Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology. ( Cannon, JR; Drolet, RE; Greenamyre, JT; Montero, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christensen, LFB | 1 |
| Alijanvand, SH | 1 |
| Burdukiewicz, M | 1 |
| Herbst, FA | 1 |
| Kjeldal, H | 1 |
| Dueholm, MS | 1 |
| Otzen, DE | 1 |
| Drolet, RE | 1 |
| Cannon, JR | 1 |
| Montero, L | 1 |
| Greenamyre, JT | 1 |
| Dizdar, N | 1 |
| Arstrand, K | 1 |
| Kågedal, B | 1 |
| Takeda, A | 1 |
| Hashimoto, M | 1 |
| Mallory, M | 1 |
| Sundsumo, M | 1 |
| Hansen, L | 1 |
| Sisk, A | 1 |
| Masliah, E | 1 |
4 other studies available for formic acid and Parkinson Disease
| Article | Year |
|---|---|
Identification of amyloidogenic proteins in the microbiomes of a rat Parkinson's disease model and wild-type rats.
Topics: alpha-Synuclein; Amino Acid Sequence; Amyloid; Amyloidogenic Proteins; Animals; Bacterial Proteins; | 2021 |
Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology.
Topics: alpha-Synuclein; Animals; Body Weight; Cell Death; Disease Models, Animal; Dose-Response Relationshi | 2009 |
Analysis of L-dopa in human serum.
Topics: Antiparkinson Agents; Chromatography, Affinity; Edetic Acid; Formates; Humans; Hydrogen-Ion Concentr | 2002 |
Abnormal distribution of the non-Abeta component of Alzheimer's disease amyloid precursor/alpha-synuclein in Lewy body disease as revealed by proteinase K and formic acid pretreatment.
Topics: alpha-Synuclein; Cadaver; Cerebral Cortex; Endopeptidase K; Formates; Humans; Immunohistochemistry; | 1998 |