formic acid has been researched along with Optic Nerve Diseases in 3 studies
formic acid: RN given refers to parent cpd
formic acid : The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methanol is an important public health and environmental concern because of the selective actions of its neurotoxic metabolite, formic acid, on the retina, optic nerve and central nervous system." | 2.41 | Development and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity. ( Eells, JT; Henry, MM; Lewandowski, MF; Murray, TG; Seme, MT, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Liberski, S | 1 |
| Kaluzny, BJ | 1 |
| Kocięcki, J | 1 |
| Sadun, A | 1 |
| Eells, JT | 1 |
| Henry, MM | 1 |
| Lewandowski, MF | 1 |
| Seme, MT | 1 |
| Murray, TG | 1 |
2 reviews available for formic acid and Optic Nerve Diseases
| Article | Year |
|---|---|
Methanol-induced optic neuropathy: a still-present problem.
Topics: Animals; Axons; Formates; Humans; Methanol; Mitochondria; Optic Nerve; Optic Nerve Diseases; Oxidati | 2022 |
Development and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity.
Topics: Animals; Disease Models, Animal; Folic Acid; Formates; Humans; Methanol; Optic Nerve; Optic Nerve Di | 2000 |
1 other study available for formic acid and Optic Nerve Diseases
| Article | Year |
|---|---|
Acquired mitochondrial impairment as a cause of optic nerve disease.
Topics: Adult; Aged; Animals; Cuba; Disease Outbreaks; Environmental Exposure; Female; Folic Acid; Formates; | 1998 |