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formic acid and Metabolic Acidosis

formic acid has been researched along with Metabolic Acidosis in 18 studies

formic acid: RN given refers to parent cpd
formic acid : The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.

Research Excerpts

ExcerptRelevanceReference
"Methanol poisoning may result in metabolic acidosis, blindness, and death."9.09Fomepizole for the treatment of methanol poisoning. ( Aaron, C; Brent, J; Kulig, K; McMartin, K; Phillips, S, 2001)
"The aim of this study is a preliminary assessment of usefulness of formic acid detection by gas chromatography in the daily practice of clinical toxicology department in methanol poisoning confirmed by the designation of this alcohol in the blood."7.80[Usefulness of blood formic acid detection in the methanol poisoning in the practice of clinical toxicology department-preliminary assessment]. ( Adamek, R; Kapala, M; Lukasik-Głębocka, M; Panieński, P; Samborski, W; Sommerfeld, K; Zielińska-Psuja, B, 2014)
"To evaluate anion and osmolal gaps as diagnostic tools in methanol poisoning."7.72Anion and osmolal gaps in the diagnosis of methanol poisoning: clinical study in 28 patients. ( Froyshov, S; Hovda, KE; Hunderi, OH; Jacobsen, D; Rudberg, N, 2004)
"Methanol poisoning may result in metabolic acidosis, blindness, and death."5.09Fomepizole for the treatment of methanol poisoning. ( Aaron, C; Brent, J; Kulig, K; McMartin, K; Phillips, S, 2001)
"The aim of this study is a preliminary assessment of usefulness of formic acid detection by gas chromatography in the daily practice of clinical toxicology department in methanol poisoning confirmed by the designation of this alcohol in the blood."3.80[Usefulness of blood formic acid detection in the methanol poisoning in the practice of clinical toxicology department-preliminary assessment]. ( Adamek, R; Kapala, M; Lukasik-Głębocka, M; Panieński, P; Samborski, W; Sommerfeld, K; Zielińska-Psuja, B, 2014)
"To evaluate anion and osmolal gaps as diagnostic tools in methanol poisoning."3.72Anion and osmolal gaps in the diagnosis of methanol poisoning: clinical study in 28 patients. ( Froyshov, S; Hovda, KE; Hunderi, OH; Jacobsen, D; Rudberg, N, 2004)
"Human methanol poisoning is characterized by formic acidemia, metabolic acidosis and blindness or serious visual impairment."3.68Methanol-induced visual toxicity in the rat. ( Eells, JT, 1991)
"A case of fatal oral poisoning with formic acid resulting in shock, metabolic acidosis, and hemolysis is reported."3.67Formic acid poisoning: case report and in vitro study of the hemolytic activity. ( Ackerman, CM; Buylaert, WA; Colardyn, FA; van den Bogaerde, JF; Verstraete, AG; Vogelaers, DP, 1989)
"Formic acid is a weaker inhibitor than cyanide and hydrosulphide anions."2.38Methanol and formic acid toxicity: biochemical mechanisms. ( Liesivuori, J; Savolainen, H, 1991)
"Formic acid levels were determined in blood samples at admission and ranged from 302 to 680 mg/L."1.31Determination of formic acid tissue and fluid concentrations in three fatalities due to methanol poisoning. ( Hantson, P; Haufroid, V; Mahieu, P, 2000)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's4 (22.22)18.2507
2000's5 (27.78)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Drangsholt, E1
Vangstad, M1
Zakharov, S1
Hovda, KE2
Jacobsen, D2
Lukasik-Głębocka, M1
Sommerfeld, K1
Kapala, M1
Adamek, R1
Panieński, P1
Zielińska-Psuja, B1
Samborski, W1
Hložek, T1
Bursová, M1
Coufal, P1
Čabala, R1
Dalus, D1
Mathew, AJ1
Somarajan Pillai, S1
Carpentieri, DF1
Wherli, S1
Pawel, B1
Henretig, FM1
Drott, HR1
Hunderi, OH1
Rudberg, N1
Froyshov, S1
Röe, O1
Chan, TC1
Williams, SR1
Clark, RF1
Stebleva, TF1
Voĭtovich, AV1
Mamaeva, EG1
Lapshangskaia, EE1
Semigolovskiĭ, NIu1
Lebedinskiĭ, KM1
Hantson, P1
Haufroid, V1
Mahieu, P2
Brent, J1
McMartin, K1
Phillips, S1
Aaron, C1
Kulig, K1
Liesivuori, J2
Savolainen, H2
Eells, JT1
van der Meer, YG1
Haasbroek, WM1
Bax, GM1
Hassoun, A1
Lauwerys, R1
Verstraete, AG1
Vogelaers, DP1
van den Bogaerde, JF1
Colardyn, FA1
Ackerman, CM1
Buylaert, WA1
Kosma, VM1
Naukkarinen, A1
Osterloh, JD1
Pond, SM1
Grady, S1
Becker, CE1

Reviews

2 reviews available for formic acid and Metabolic Acidosis

ArticleYear
Species differences in methanol poisoning.
    Critical reviews in toxicology, 1982, Volume: 10, Issue:4

    Topics: Acidosis; Animals; Blindness; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Formal

1982
Methanol and formic acid toxicity: biochemical mechanisms.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:3

    Topics: Acidosis; Animals; Electron Transport Complex IV; Formates; Humans; Hydrogen-Ion Concentration; Meth

1991

Trials

1 trial available for formic acid and Metabolic Acidosis

ArticleYear
Fomepizole for the treatment of methanol poisoning.
    The New England journal of medicine, 2001, Feb-08, Volume: 344, Issue:6

    Topics: Acidosis; Adolescent; Adult; Alcohol Dehydrogenase; Antidotes; Enzyme Inhibitors; Female; Fomepizole

2001

Other Studies

15 other studies available for formic acid and Metabolic Acidosis

ArticleYear
The Hypothesis of Circulus Hypoxicus and Its Clinical Relevance in Patients With Methanol Poisoning - An Observational Study of 35 Patients.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:6

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Adolescent; Adult; Aged; Blood Gas Analysis; F

2018
[Usefulness of blood formic acid detection in the methanol poisoning in the practice of clinical toxicology department-preliminary assessment].
    Przeglad lekarski, 2014, Volume: 71, Issue:9

    Topics: Acidosis; Alcoholism; Biomarkers; Chromatography, Gas; Ethanol; Formates; Humans; Male; Methanol; Mi

2014
Identification and quantification of acidosis inducing metabolites in cases of alcohols intoxication by GC-MS for emergency toxicology.
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: Acetates; Acidosis; Alcoholic Intoxication; Blood Chemical Analysis; Calibration; Chemistry Techniqu

2015
Formic acid poisoning in a tertiary care center in South India: A 2-year retrospective analysis of clinical profile and predictors of mortality.
    The Journal of emergency medicine, 2013, Volume: 44, Issue:2

    Topics: Acidosis; Acute Kidney Injury; Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Chemi

2013
Potential applications of proton nuclear magnetic resonance spectroscopy in the diagnosis and management of methanol intoxication in the pediatric population.
    Pediatric emergency care, 2003, Volume: 19, Issue:3

    Topics: Accidents, Home; Acidosis; Blood Chemical Analysis; Dyspnea; Emergencies; Formates; Humans; Infant;

2003
Anion and osmolal gaps in the diagnosis of methanol poisoning: clinical study in 28 patients.
    Intensive care medicine, 2004, Volume: 30, Issue:9

    Topics: Acid-Base Equilibrium; Acidosis; Chromatography, Gas; Formates; Humans; Linear Models; Methanol; Obs

2004
Formic acid skin burns resulting in systemic toxicity.
    Annals of emergency medicine, 1995, Volume: 26, Issue:3

    Topics: Acidosis; Burns, Chemical; Child, Preschool; Female; Formates; Humans; Renal Dialysis; Sodium Bicarb

1995
[Mechanisms of the optimization of oxygen metabolism under the effects of mafusol and mildronate during emergency implantation of hip prosthesis].
    Vestnik khirurgii imeni I. I. Grekova, 2000, Volume: 159, Issue:1

    Topics: Acid-Base Equilibrium; Acidosis; Adjuvants, Immunologic; Aged; Aged, 80 and over; Arthroplasty, Repl

2000
Determination of formic acid tissue and fluid concentrations in three fatalities due to methanol poisoning.
    The American journal of forensic medicine and pathology, 2000, Volume: 21, Issue:4

    Topics: Acidosis; Adult; Chromatography, Gas; Ethanol; Fatal Outcome; Female; Formates; Humans; Male; Methan

2000
Methanol-induced visual toxicity in the rat.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: Acidosis; Animals; Electroretinography; Evoked Potentials; Formates; Male; Methanol; Rats; Rats, Inb

1991
[Poisoning with ammonium tetraformiate--a substance used in silage formation].
    Nederlands tijdschrift voor geneeskunde, 1990, Jun-30, Volume: 134, Issue:26

    Topics: Acidosis; Adult; Agricultural Workers' Diseases; Formates; Hemoglobinuria; Hemolysis; Humans; Male;

1990
Predictors of methanol intoxication with unfavourable outcome.
    Human toxicology, 1989, Volume: 8, Issue:2

    Topics: Acidosis; Adult; Carbon Dioxide; Female; Formates; Humans; Male; Methanol

1989
Formic acid poisoning: case report and in vitro study of the hemolytic activity.
    The American journal of emergency medicine, 1989, Volume: 7, Issue:3

    Topics: Acidosis; Adult; Blood Chemical Analysis; Critical Care; Female; Formates; Half-Life; Hemolysis; Hum

1989
Kinetics and toxic effects of repeated intravenous dosage of formic acid in rabbits.
    British journal of experimental pathology, 1987, Volume: 68, Issue:6

    Topics: Acidosis; Animals; Brain; Calcium; Formates; Histocytochemistry; Hypoxia; Injections, Intravenous; K

1987
Serum formate concentrations in methanol intoxication as a criterion for hemodialysis.
    Annals of internal medicine, 1986, Volume: 104, Issue:2

    Topics: Acidosis; Adult; Bicarbonates; Ethanol; Eye Diseases; Folic Acid; Formates; Humans; Male; Methanol;

1986